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Protective activities of probiotics in letrozole-induced polycystic ovarian syndrome (PCOS) rats
Xinyu Li,Chenyang Xie,Qiuping Huang,Eun Mi Hwang,Bin Jin,Zhewen Dong,Zhen Zeng,Wen He,Qi Qi Pang,Jia-Le Song 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
To investigate the effect of Bifidobacterium, C. butyricum and L. plantarum on the letrozole induced PCOS rats. All female SD rats were randomly divided into five groups, modeling PCOS rats, and respectively given intragastric administration of Bifidobacterium, C. butyricum, and L. plantarum solution (1×10<SUP>9</SUP> CFU/mL) for 30 days, and observed body weight (BW). The serum levels of testosterone (T), LH, E2, FSH, INS, TG, TC, LDL, HDL were determined by ELISA kits. The levels of TGF-β1, smad4, smad3, p-smad3, p-smad2, smad2 were detected by Western Blotting. Compared with normal group, the BW, T, LH, INS, TG, TC LDL-C in PCOS rats were significantly increased, and the levels of E2, FSH and HDL-C were significantly decreased. Administrated with different probiotics can decrease the BW, T, LH, INS, TG, TC,LDL-C, and the levels of E2, FSH and HDL-C increased in PCOS rats. All probiotics significantly decreased the expression of p-smad2, p-smad3, smad4, TGF-β1. Our results showed that Bifidobacterium, C. butyricum and L. plantarum were all effective in regulating hormone levels, improving IR and dyslipidemia, and improving ovarian fibrosis in PCOS rats.
Huang, Chuanzhen,Zhu, Hongtao,Lu, Xinyu,Li, Quanlai,Che, Cuilian Korean Society for Precision Engineering 2008 International Journal of Precision Engineering and Vol.9 No.2
Critical erosion kinetic energy models for radial/median cracks and lateral cracks in a workpiece are established in this study. We used experimental results to demonstrate that the fracture erosion resistance and erosion machining number could be used to evaluate the brittle fracture resistance and machinability of a workpiece. Erosion kinetic energy models were developed to predict brittle fracture and ductile shear, and a critical erosion kinetic energy model was developed to predict the transition from brittle fracture to ductile shear. These models were verified experimentally.
양황 ( Huang Yang ),신상범 ( Sangbum Shin ),리신위 ( Xinyu Li ) 한국유라시아학회 2023 세계와 유라시아 Vol.2 No.1
Using the China Innovation Talent Index indicators as a benchmark for talent innovation, this study comprehensively analyzed the evolving characteristics of innovative talent in China over the past two years. Using data from the top 50 cities ranked by the China Innovation Talent Index in 2021, we employed multivariate linear regression analysis to investigate the potential impact of each factor on China's economy. The findings reveal a polarization in the distribution of innovative talent in China during this period, with a substantial concentration of such talent in the southeast and coastal regions. Our analysis indicates that talent concentration, patent grants, and technology market transaction volumes exert a favorable influence on the economic growth of these regions. In contrast, other facets of the innovation drive do not have a significant impact. Furthermore, our findings indicate the positive effect of the interaction between talent concentration and innovation on economic growth, whereas local government intervention has a detrimental impact. Consequently, the intricate relationship between talent concentration, innovation drive, and economic growth warrants further investigation.
Sensorless Control of the Switched Reluctance Motor Based on the Sliding-Mode Observer
Li Xinyu,Liu Jiayu,Ge Lefei,Zhong Jixi,Huang Jiale,Zhao Yuchen,Song Shoujun 대한전기학회 2023 Journal of Electrical Engineering & Technology Vol.18 No.2
To upgrade the application of switched reluctance motors (SRMs) for more electric aircraft, this paper presents a method with sensorless control based on the flux-linkage data from the finite element method. First, a calibration strategy is employed to obtain the flux-linkage characteristics. Then, a sliding-mode observer is used to realize the sensorless control of the SRM. The proposed method only requires the flux-linkage of the SRM at aligned and unaligned rotor positions from the experiment which takes a low-measurement effort to get the rotor position and has better accuracy in position and speed estimation than the FEM. Experimental results verify the accuracy and effectiveness of the proposed method.
HUI HUANG,JIN-GANG YU,Wei Liu,XINYU JIANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2015 NANO Vol.10 No.5
In this study, amino-functionalized multi-walled carbon nanotubes (MWCNTs-NH2) were successfully synthesized via an improved method and used for removal of organic dyes in aqueous solution. The synthesized MWCNTs-NH 2 were characterized by Fourier transform infrared (FTIR) spectroscopy, thermogravimetric analysis (TGA), scanning electron microscope (SEM), etc. The adsorption capacity and selectivity of MWCNTs-NH 2 for organic dyes was evaluated using rhodamine B (RhB), malachite green (MG), methyl orange (MO) and congo red (CR) as models. The selective adsorption toward anionic dyes was found for the MWCNTs-NH2 , and MO was selected as a typical anionic dye to deeply investigate the adsorption kinetics, equilibrium isotherms and thermodynamic parameters of the adsorption process. The adsorption kinetics and equilibrium isotherms data fitted well with the pseudo-second-order kinetic equation and Langmuir isotherm model. The thermodynamics study revealed that the adsorption of MO onto MWCNTs-NH2 was spontaneous, exothermic and physisorptive in nature. The results indicated that MWCNTs-NH2 are promising nanomaterials for removal of anionic dyes from industrial wastewater.
Qiuping Huang,Chenyang Xie,Xinyu Li,Bin Jin,Qi Pang,Jia-Le Song 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10
To explore the effect of LTA on clinical symptoms in letrozole-induced PCOS rats. Female SD rats were given letrozole for 28 consecutive days to induce the PCOS model. The PCOS rats were given LTA intervention(50 and 200 mg/kg) for 30 days. Changes in body weight and estrous cycle were observed. Serum levels of hormones and lipids were measured by ELISA assay. Protein levels of α-SMA, p-smad2, smad2, p-smad3, smad3 and smad4 were detected by Western Blotting assay. Compared with the normal group, the relative mass of abdominal fat, T, LH, INS, TG, TC and LDL-C were significantly increased, and the levels of E2, FSH and HDL-C were significantly decreased in PCOS rats. The protein levels of p-smad2, p-smad3, smad4 and α-SMA were significantly upregulated in the ovaries of PCOS rats(P<0.05). While the levels of T, LH, INS, TG, TC, LDL-C were decreased and E2, FSH and HDL-C level were increased by LTA treatment. Meanwhile, LTA reduced the protein levels of p-smad2, p-smad3, smad4, and α-SMA in the ovaries. The results suggested LTA was effective in regulating the hormone levels, improving metabolism, and alleviating ovarian fibrosis in PCOS rats.
Chuanzhen Huang,Hongtao Zhu,Xinyu Lu,Quanlai Li,Cuilian Che 한국정밀공학회 2008 International Journal of Precision Engineering and Vol.9 No.2
Critical erosion kinetic energy models for radial/median cracks and lateral cracks in a workpiece are established in this study. We used experimental results to demonstrate that the fracture erosion resistance and erosion machining number could be used to evaluate the brittle fracture resistance and machinability of a workpiece. Erosion kinetic energy models were developed to predict brittle fracture and ductile shear, and a critical erosion kinetic energy model was developed to predict the transition from brittle fracture to ductile shear. These models were verified experimentally.
HUI HUANG,JIN-GANG YU,XINYU JIANG 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2014 NANO Vol.9 No.8
A facile and effective approach based on magnetic separation was developed for the adsorption of Rhodamine B (RhB) from aqueous solution using magnetic oxidized multi-walled carbon nanotubes (magnetic o-MWCNTs) as adsorbent. The magnetic o-MWCNTs were simply synthesized by assembling magnetic nanoparticles onto the oxidized MWCNTs. Adsorption conditions such as pH values, the dosage of adsorbent added and adsorption time were investigated and optimized to achieve the best removal value. In addition, kinetics, adsorption isotherms and adsorption thermodynamics were studied to understand the mechanism by which the magnetic o-MWCNTs adsorbed RhB. The results indicated that the proposed method based on magnetic o-MWCNTs as magnetic absorbent was rapid and e±cient for the removal of RhB. Furthermore, the magnetic o-MWCNTs could be easily removed after adsorption process and regenerated through desorption by ethanol.
Energy-saving Design Method for Hydraulic Press Drive System with Multi Motor-Pumps
Haihong Huang,Xiang Zou,Lei Li,Xinyu Li,Zhifeng Liu 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.6 No.2
Large energy consumption caused by the pump unloading, as well as the low energy efficiency of the motor, is a serious problem for hydraulic presses especially for the press with multi motor-pumps. By analyzing the energy dissipation characteristic of hydraulic press drive system which is composed of several motor-pumps used to provide energy, an energy-saving design method is developed to reduce the energy loss of the drive system. In this method, pumps are selected from the pump set by minimizing the proposed idling index to reduce the energy loss of motor-pumps in the unloading state. The index is defined as the sum of the product of the unloaded flow and the unloaded time for each stage in a working cycle of the hydraulic press. Then, the motors are selected from the motor set to drive the selected pumps correspondingly by ensuring that the load rate of all the motors is within a setting range for high energy efficiency in as many stages as possible. The method was applied to a 2000-ton rapid sheet tension hydraulic press, and results indicate that 26.97% of energy can be saved in a working cycle.
Model-Free Adaptive Integral Backstepping Control for PMSM Drive Systems
Hongmei Li,Xinyu Li,Zhiwei Chen,Jingkui Mao,Jiandong Huang 전력전자학회 2019 JOURNAL OF POWER ELECTRONICS Vol.19 No.5
A SMPMSM drive system is a typical nonlinear system with time-varying parameters and unmodeled dynamics. The speed outer loop and current inner loop control structures are coupled and coexist with various disturbances, which makes the speed control of SMPMSM drive systems challenging. First, an ultra-local model of a PMSM driving system is established online based on the algebraic estimation method of model-free control. Second, based on the backstepping control framework, modelfree adaptive integral backstepping (MF-AIB) control is proposed. This scheme is applied to the permanent magnet synchronous motor (PMSM) drive system of an electric vehicle for the first time. The validity of the proposed control scheme is verified by system simulations and experimental results obtained from a SMPMSM drive system bench test.