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        Analysis of Undrained Shear Characteristics and Structural Damage of Granite Residual Soil

        Song Yin,Pengfei Liu,Pan Yan,Xianwei Zhang,Xinming Li 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.9

        Three-dimensional consolidation testing, scanning electron microscopy, and undrained triaxial testing of granite residual soil (GRS) in Shenzhen, China, were conducted. The effect of the structural strength of GRS was quantitatively analyzed using the method of comprehensive structure potential parameter description. The failure strength ratio of the soil decreases with increasing confining pressure, and it is approximately 1 when the confining pressure is higher than the yield stress (σs). The undrained shear strength (Su) of the undisturbed soil varies in stages with confining pressure σ3. The relationship between Su and σ3 for the reconstituted soil is approximated as a straight line through the origin. The soil’s comprehensive structure potential parameters (the structural contribution rates of the tangential shear modulus, mE, and the deviatoric stress, md) decrease linearly with increasing σ3. The mE and md sample values are similar under the same confining pressure. It is reasonable to use structure potential parameters to quantitatively evaluate the structure contribution rate of GRS. The microstructure is constantly adjusted, and the soil microstructure form for different confining pressures strongly correlates with its shear characteristics.

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        Alterations in Spontaneous Brain Activity in Drug-Naïve First-Episode Schizophrenia: An Anatomical/Activation Likelihood Estimation Meta-Analysis

        Xiaolei Qiu,Rongrong Zhang,Lu Wen,Fuli Jiang,Hongjun Mao,Wei Yan,Shiping Xie,Xinming Pan 대한신경정신의학회 2022 PSYCHIATRY INVESTIGATION Vol.19 No.8

        Objective The etiology of schizophrenia is unknown and is associated with abnormal spontaneous brain activity. There are no consistent results regarding the change in spontaneous brain activity of people with schizophrenia. In this study, we determined the specific changes in the amplitude of low-frequency fluctuation/fractional amplitude of low-frequency fluctuation (ALFF/fALFF) and regional homogeneity (ReHo) in patients with drug-naïve first-episode schizophrenia (Dn-FES). Methods A comprehensive search of databases such as PubMed, Web of Science, and Embase was conducted to find articles on resting-state functional magnetic resonance imaging using ALFF/fALFF and ReHo in schizophrenia patients compared to healthy controls (HCs) and then, anatomical/activation likelihood estimation was performed. Results Eighteen eligible studies were included in this meta-analysis. Compared to the spontaneous brain activity of HCs, we found changes in spontaneous brain activity in Dn-FES based on these two methods, mainly including the frontal lobe, putamen, lateral globus pallidus, insula, cerebellum, and posterior cingulate cortex. Conclusion We found that widespread abnormalities of spontaneous brain activity occur in the early stages of the onset of schizophrenia and may provide a reference for the early intervention of schizophrenia

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