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Towards Attacks and Defenses of Anonymous Communication Systems
Tianbo Lu,Puxin Yao1,Lingling Zhao,Yang Li,Feng Xie,Yamei Xia 보안공학연구지원센터 2015 International Journal of Security and Its Applicat Vol.9 No.1
Anonymous communication system has been hot topic in the field of information security, and attack techniques against anonymous systems are endless. This paper first classifies and summarizes the study of attacks against anonymous communication system in recent years, then analyzes the trend of the research on different attack technologies; secondly, it provides a comparative analysis of defense capability the mainstream anonymous communication system to the various attacks; Finally, combining the advantages and disadvantages of different systems, the authors propose an improved node selection and router forwarding algorithms for anonymous communication systems, and design an architecture of anonymous communications software based on the algorithm.
Qin, Li-Li,Wang, Qin-Rong,Wang, Qian,Yao, Hong,Wen, Li-Jun,Wu, Li-Li,Ping, Na-Na,Xie, Jun-Dan,Chen, Mei-Yu,Chen, Su-Ning Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.12
The diagnosis of latent Mycobacterium tuberculosis infection (LTBI) is recommended in hematological malignancy patients and before hematopoietic stem cell transplantation (Guidelines for the prevention and management of infectious complications of solid organ transplantation, 2004). Compared to traditional methods such as tuberculin skin test (TST), T-SPOT.TB has been shown to be more specific. In the present study we enrolled 536 patients for whom T-SPOT.TB was performed, among which 295 patients also received the TST test. The agreement (79%) between T-SPOT.TB and TST was poor (x=0.274, P<0.001). The patients with positive T-SPOT.TB results numbered 62 (11.6%), in which only 20 (48.8%) of the 41 receiving the TST test had positive results. A majority of the patients with T-SPOT.TB positive results had some other evidence ofTB, such as TB history, clinical symptoms and an abnormal chest CT scan. Active TB was found in 9 patients, in which 2 had negative TST results. We followed up the patients and no one developed active TB. Our study suggested that the T-SPOT.TB may be more useful for screening LTBI and active TB in hematological malignancy patients and hematopoietic stem cell transplant recipients than the TST test.
Li Yao,Yongqun Zhu,Wenzhi Xu,Hong Wang,Xie Wang,Jianhua Zhang,Haitao Liu,Chaowen Lin 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.72 No.-
In this study, the combination of dispersive solid phase extraction (DSPE) with dispersive liquid–liquidmicroextraction (DLLME) was proposed as a novel sequential speciation method for Cr determination bygraphite furnace atomic absorption spectrometry. In thefirst step, the selective extraction of Cr(III) byDSPE was achieved using graphene oxide (GO) nanoparticles as the adsorbent. The difficulty of separationand collection of GO in analytical performance was solved by the introduction of the syringe nanofilter. Then Cr(VI) was enriched by DLLME using [Omim] [PF6] as the extraction solvent. The experimentalparameters affecting the performance of both preconcentration methods were investigated andoptimized. Under the optimal conditions including the initial pH value of 7, 150 mg GO, 2 min ultrasoundtime, 210 mL elution solvent (first step), secondary pH value of 4, 0.15% (m/v) Aliquat-336, 120 mL of[Omim] [PF6] and 3 min ultrasound time (second step), the linear range of 0.06–5 ng/mL (R > 0.997), thelimits of detection of 0.015 and 0.02 ng/mL were achieved for Cr(III) and Cr(VI), respectively. The relativestandard deviations (n = 5) of 0.6 ng/mL Cr(III) and Cr(VI) were 3.2% and 4.6%, respectively. Finally, thisnewly developed method was applied for the speciation and determination of Cr species in differentwater samples and satisfactory results were obtained.
Li Yao,Xie Wang,Haitao Liu,Chaowen Lin,Liangyu Pang,Junwei Yang,Qingbin Zeng 한국공업화학회 2017 Journal of Industrial and Engineering Chemistry Vol.56 No.-
A simple and efficient method for the determination of Cd and Pb in water samples was developed byultrasound-assisted magnetic retrieval-linked ionic liquid dispersive liquid–liquid microextraction (UA-MR-IL-DLLME) preconcentration and graphite furnace atomic absorption spectrometry (GFAAS)detection. Ionic liquid (IL) [Hmim] [PF6] was used as the extractant, ammonium pyrrolidinedithiocarbamate (APDC) as the complexing agent and Fe3O4 nanoparticles as the sorbent, whileultrasound was applied to assist the dispersion of the extractant and accelerate the mass transfer process. The effect of different factors on the extraction efficiency including pH, IL volume, APDC amount,ultrasound extraction time, ultrasound desorption time and Fe3O4 amount was studied by a fractionalfactorial design to screen for the most important factors. Then a central composite design was used tooptimize the significant factors. Under the optimal conditions, the method has linear calibration curvesover the range of 0.3–20 ng/mL for Cd and 0.5–40 ng/mL for Pb, with correlation coefficients (R) of0.9990 and 0.9986 for Cd and Pb, respectively. The limits of detection were 0.1 ng/mL and 0.15 ng/mL withrelative standard deviations of 3.4% and 2.8% for Cd and Pb, respectively. Finally, the method wassuccessfully applied for the determination of Cd and Pb in the real water samples and satisfactoryrecoveries were achieved.
Li, Chen-Long,Chang, Liang,Guo, Lin,Zhao, Dan,Liu, Hui-Bin,Wang, Qiu-Shi,Zhang, Ping,Du, Wen-Zhong,Liu, Xing,Zhang, Hai-Tao,Liu, Yang,Zhang, Yao,Xie, Jing-Hong,Ming, Jian-Guang,Cui, Yu-Qiong,Sun, Ying Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.23
Background: ${\beta}$-elemene, extracted from herb medicine Curcuma wenyujin has potent anti-tumor effects in various cancer cell lines. However, the activity of ${\beta}$-elemene against glioma cells remains unclear. In the present study, we assessed effects of ${\beta}$-elemene on human glioma cells and explored the underlying mechanism. Materials and Methods: Human glioma U87 cells were used. Cell proliferation was determined with MTT assay and colony formation assay to detect the effect of ${\beta}$-elemene at different doses and times. Fluorescence microscopy was used to observe cell apoptosis with Hoechst 33258 staining and change of glioma apoptosis and cell cycling were analyzed by flow cytometry. Real-time quantitative PCR and Western-blotting assay were performed to investigated the influence of ${\beta}$-elemene on expression levels of Fas/FasL, caspase-3, Bcl-2 and Bax. The experiment was divided into two groups: the blank control group and ${\beta}$-elemne treatment group. Results: With increase in the concentration of ${\beta}$-elemene, cytotoxic effects were enhanced in the glioma cell line and the concentration of inhibited cell viability ($IC_{50}$) was $48.5{\mu}g/mL$ for 24h. ${\beta}$-elemene could induce cell cycle arrest in the G0/G1 phase. With Hoechst 33258 staining, apoptotic nuclear morphological changes were observed. Activation of caspase-3,-8 and -9 was increased and the pro-apoptotic factors Fas/FasL and Bax were upregulated, while the anti-apoptotic Bcl-2 was downregulated after treatment with ${\beta}$-elemene at both mRNA and protein levels. Furthermore, proliferation and colony formation by U87 cells were inhibited by ${\beta}$-elemene in a time and does-dependent manner. Conclusions: Our results indicate that ${\beta}$-elemene inhibits growth and induces apoptosis of human glioma cells in vitro. The induction of apoptosis appears to be related with the upregulation of Fas/FasL and Bax, activation of caspase-3,-8 and -9 and downregulation of Bcl-2, which then trigger major apoptotic cascades.
A strategy to overcome the limits of carbon-based materials as lithium-ion battery anodes
Yao, F.,Li, B.,So, K.,Chang, J.,Ly, T.H.,Vu, A.Q.,Mun, H.,Cojocaru, C.S.,Yue, H.,Xie, S.,Lee, Y.H. Pergamon Press ; Elsevier Science Ltd 2014 Carbon Vol.79 No.-
The free-standing Si-coated carbon nanofiber (Si/CNF) mat was fabricated for the anode of lithium ion battery through combining electrospun CNF mat with electrodeposited Si layer. Spaghetti or granule-like Si was obtained by varying the deposition conditions. This Si/CNF mat was directly used as an active material and a current collector as well, which involves neither binders nor additional metal substrate. The best performance was achieved in spaghetti-like Si due to its highly porous nature which can accommodate volume expansion and large surface area which benefit the efficient charge transfer both at Si/CNF interface and at the electrode/electrolyte interface. The optimized Si/CNF mat after annealing at 1000<SUP>o</SUP>C delivered a capacity of 870mAhg<SUP>-1</SUP> at 1st discharge and 730mAhg<SUP>-1</SUP> at 50th discharge with a capacity retention of 84%, improving the capacity of pure CNF (280mAhg<SUP>-1</SUP> at the 50th discharge) by almost three times. In addition, corrosion of the current collector no longer exists in our approach. Our X-ray photoemission spectroscopy and electrochemical analysis revealed that the formation of Si-C bond through high temperature annealing can enhance the adhesion between silicon and carbon at the interface which benefits the cyclic performance of anode ultimately.
Routing Protocol for Wireless Sensor Networks Based on Virtual Force Disturbing Mobile Sink Node
Yindi Yao,Dangyuan Xie,Chen Wang,Ying Li,Yangli Li 한국인터넷정보학회 2022 KSII Transactions on Internet and Information Syst Vol.16 No.4
One of the main goals of wireless sensor networks (WSNs) is to utilize the energy of sensor nodes effectively and maximize the network lifetime. Thus, this paper proposed a routing protocol for WSNs based on virtual force disturbing mobile Sink node (VFMSR). According to the number of sensor nodes in the cluster, the average energy and the centroid factor of the cluster, a new cluster head (CH) election fitness function was designed. At the same time, a hexagonal fixed-point moving trajectory model with the best radius was constructed, and the virtual force was introduced to interfere with it, so as to avoid the frequent propagation of sink node position information, and reduce the energy consumption of CH. Combined with the improved ant colony algorithm (ACA), the shortest transmission path to Sink node was constructed to reduce the energy consumption of long-distance data transmission of CHs. The simulation results showed that, compared with LEACH, EIP-LEACH, ANT-LEACH and MECA protocols, VFMSR protocol was superior to the existing routing protocols in terms of network energy consumption and network lifetime, and compared with LEACH protocol, the network lifetime was increased by more than three times.
Xi-sheng Xie,Fei-yan Li,Heng-chuan Liu,Yao Deng,Zi Li,Jun-ming Fan 대한약학회 2010 Archives of Pharmacal Research Vol.33 No.2
The effects of LSKL, the peptide antagonist of thrombospondin-1 (TSP-1), on renal interstitial fibrosis in rats subjected to unilateral ureteral obstruction (UUO) were investigated. Rats were divided randomly into three groups (n = 20 each): UUO group, sham-operation group and UUO plus LSKL treatment group. Collagen deposition was studied using histopathology and reverse transcription polymerase chain reaction analysis (RT-PCR). TSP-1, transforming growth factor beta 1 (TGF-β1), phosphorylated Smad2 (pSsmad2) and α-smooth muscle actin (α-SMA) in the kidney were measured using immunocytochemistry, western blotting analysis, RT-PCR and enzyme-linked immunosorbent assay. Biochemical analyses in the serum and urine were made. Histopathology showed severe tubular dilatation and atrophy, interstitial inflammation and collagen accumulation after surgery and LSKL significantly inhibited interstitial fibrosis including tubular injury as well as collagen deposition. The protein and mRNA levels of TSP-1 increased notably at different time point and significantly decreased in the presence of LSKL. The expression of TGF-β1 and pSmad2 were upregulated in the obstructed kidney and substantially suppressed by LSKL treatment. Myofibroblast accumulation could be alleviated after administration of LSKL. Biochemical parameters did not show differences among the three groups. As TSP-1 is the major activator of TGF-β1, we demonstrate that LSKL can attenuate renal interstitial fibrosis in vivo by preventing TSP-1-mediated TGF-β1 activation.