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      • Dynamical evolution of public perceptions of technological innovation in supernetwork

        Xiaoyue Qiu,Xiaqun Liu,Yaming Zhuang 제어로봇시스템학회 2022 제어로봇시스템학회 국제학술대회 논문집 Vol.2022 No.11

        This paper studies the evolution of public perceptions of technological innovation based on the supernetwork involving social subnetwork, information subnetwork, and knowledge subnetwork. The interaction rules of nodes with different attributes among all the subnetworks are designed by using the multi-agent modeling method. By simulations, we find that with the increase of the public knowledge level or the expansion of the information dissemination range, the public perceptions have gradually improved, but the improvement of public perceptions has a marginal diminishing effect. Besides, the impact of information professionalism on public perceptions will be affected by the range of information dissemination, when the range of information dissemination is small, reducing the professionalism of information can improve the public perceptions; but when the range of information dissemination is large, the professionalism of information has little effect on the evolution of public perceptions. Meanwhile, the trust threshold caused by different knowledge level and the social network structure will affect the convergence of public perceptions.

      • KCI등재

        Heterologous prime-boost immunization with live SPY1 and DnaJ protein of Streptococcus pneumoniae induces strong Th1 and Th17 cellular immune responses in mice

        Yulan Qiu,XueMei Zhang,Hong Wang,Xinyuan Zhang,Yunjun Mo,Xiaoyu Sun,Jichao Wang,YiBing Yin,WenChun Xu 한국미생물학회 2017 The journal of microbiology Vol.55 No.10

        diseases in children under 5-year-old. Vaccine has been used as an indispensable strategy to prevent S. pneumoniae infection for more than 30 years. Our previous studies confirmed that mucosal immunization with live attenuated strain SPY1 can protect mice against nasopharyngeal colonization of S. pneumoniae and lethal pneumococcal infection, and the protective effects are comparable with those induced by commercially available 23-valent polysaccharide vaccine. However, live attenuated vaccine SPY1 needs four inoculations to get satisfactory protective effect, which may increase the risk of virulence recovery. It is reported that heterologous primeboost approach is more effective than homologous primeboost approach. In the present study, to decrease the doses of live SPY1 and improve the safety of SPY1 vaccine, we immunized mice with SPY1 and DnaJ protein alternately. Our results showed that heterologous prime-boost immunization with SPY1 and DnaJ protein could significantly reduce the colonization of S. pneumoniae in the respiratory tract of mice, and induce stronger Th1 and Th17 cellular immune responses than SPY1 alone. These results indicate heterologous prime-boost immunization method not only elicits better protective effect than SPY1 alone, but also reduces the doses of live SPY1 and decreases the risk of SPY1 vaccine. This work is the first time to study the protective efficiency with two different forms of S. pneumoniae candidate vaccine, and provides a new strategy for the development of S. pneumoniae vaccine.

      • KCI등재후보

        AN ECONOMICAL VELOCITY PLANNING ALGORITHM FOR INTELLIGENT CONNECTED EVS BASED ON REAL-TIME TRAFFIC INFORMATION

        Mingming Qiu,Lei Wang,Xiaoyu Mu,Wei Yu,Kang Huang 한국자동차공학회 2024 International journal of automotive technology Vol.25 No.2

        The energy effi ciency of intelligent networked connected electric vehicle (EV) is directly related to its velocity. Aiming atthe infl uence of real-time traffi c fl ow information on road speed interval, a two-layer speed planning method is proposed. The upper layer extracts the road speed interval according to the traffi c fl ow information, and based on cellular automata andconfi dence interval theory, traffi c information rules are introduced, and a road speed interval extraction method consideringtraffi c density information is established. The lower layer is used to obtain energy-optimal cruising velocity profi le. Takingthe road speed interval as the variable boundary constraint, a dynamic programming algorithm that changes the state quantityboundary in real time is designed, which realizes the effi cient acquisition of the energy-optimized velocity trajectory. To verify the eff ectiveness of proposed approach, the simulation model is formulated based on using collected real traffi cinformation. The simulation results demonstrate that, compared with the conventional constant speed cruising strategy anddynamic programming (DP) strategy based on road speed interval, the strategy proposed in this study not only improvesenergy effi ciency and reduces computing time signifi cantly, but also can predict the traffi c conditions ahead to avoid largefl uctuations in velocity. Besides, the biggest signifi cance of this study is the designed economic velocity planning algorithmbased on real-time traffi c density information improves the adaptability of intelligent networked connected EV controlstrategy to actual traffi c conditions, and extends the optimization dimension of eco-driving.

      • KCI등재

        Synthesis and Characterization of Ag@polycarbazole Coaxial Nanocables and their Enhanced Dispersion Behavior

        Ahmad Zahoor,Qiu Teng,Haiqiao Wang,M. A Choudhry,Xiaoyu Li 대한금속·재료학회 2011 METALS AND MATERIALS International Vol.17 No.3

        Ag@polycarbazole coaxial nanocables (CNCs) have been successfully fabricated by the oxidative polymerization of carbazole over Ag nanowires (NWs) in acetonitrile. The morphology of Ag NWs and CNCs was studied by employing a transmission electron microscope (TEM) and a scanning electron microscope (SEM), which showed them to be a monodisperse material. The thickness of the polymer sheath was found to be 5 nm to 8 nm by observation under a high-resolution transmission electron microscope (HR-TEM). Energy dispersive X-ray spectroscopy (EDS), FT-IR and Raman measurements were used to characterize the polymer sheath, which demonstrated it to be a carbon material in polycarbazole form. X-ray photoelectron spectroscopy (XPS) was used for an interfacial study, which revealed that Ag surface atoms remained intact during polymer growth. In the end, zeta potential showed that the dispersion stability of Ag NWs increased due to polymer encapsulation, which is significant to obtain a particular alignment for anisotropic measurement of electrical conductivity.

      • KCI등재후보

        Shear bond failure in composite slabs– a detailed experimental study

        Shiming Chen,Xiaoyu Shi,Zihao Qiu 국제구조공학회 2011 Steel and Composite Structures, An International J Vol.11 No.3

        An experimental study has been carried out to reveal the shear-bond failure mechanism of composite deck slabs. Thirteen full scale simply supported composite slabs are studied experimentally, with the influence parameters like span length, slab depth, shear span length and end anchorage provided by steel headed studs. A dozen of strain gauges and LVDTs are monitored to capture the strain distribution and variation of the composite slabs. Before the onset of shear-bond slip, the longitudinal shear forces along the span are deduced and found to be proportional to the vertical shear force in terms of the shear-bond strength in the m-k method. The test results are appraised using the current design procedures. Based on the partial shear-bond connection at the ultimate state, an improved method is proposed by introducing two reduction factors to assess the moment resistance of a composite deck slab. The new method has been validated and the results predicted by the revised method agree well with the test results.

      • KCI등재

        Identification of differentially expressed miRNAs after Lactobacillus reuteri treatment in the ileum mucosa of piglets

        Qi Wang,Qian Sun,Jing Wang,Xiaoyu Qiu,Renli Qi,Jinxiu Huang 한국유전학회 2020 Genes & Genomics Vol.42 No.11

        Background Lactobacillus reuteri I5007 possesses many excellent probiotic characteristics in piglets. miRNA plays importantrole in host-microbiota interactions, but the mechanism by which L. reuteri I5007 regulates intestinal function throughits influence on miRNA expression is unknown. Objective This study analyzed the miRNA expression patterns in the ileum mucosa tissue of piglets by L. reuteri I5007treatment, aim to clarify its molecular mechanism for regulating intestinal function through miRNA. Methods Neonatal piglets were orally administered L. reuteri I5007 or a placebo daily starting on day 1, and differentialexpression of ileal miRNAs was analyzed at 10 and 20 days of age by small RNA sequencing. Results 361 known porcine miRNAs were identified, and ten miRNAs were highly expressed in the ileum mucosa in bothtreatments. Nineteen differentially expressed (DE) miRNAs were identified in response to L. reuteri treatment, and four DEmiRNAs (ssc-miR-196a, -196b-5p, -1285 and -10386) were differentially expressed at both time points. The KEGG pathwayanalyses showed the targets of 19 DE miRNAs were involved in 63 significantly enriched pathways, including the PI3KAktand MAPK pathways, which were confirmed to play important roles in probiotic-host communication. L. reuteri I5007exerted anti-inflammatory effects by influencing the levels of inflammatory cytokines. Suppressor of cytokine signalling 4gene was the target gene of ssc-miR-196a/-196b-5p, overexpression of ssc-miR-196a/-196b-5p downregulated the mRNAexpression of IL-1β and TNFα in IPEC-J2 cells. Conclusion Our study provides new insight into the role of miRNAs in the intestinal function of piglets after L. reuteriI5007 treatment.

      • KCI등재

        Three-dimensional thermal-hydraulics/neutronics coupling analysis on the full-scale module of helium-cooled tritium-breeding blanket

        Lian Qiang,Tang Simiao,Zhu Longxiang,Zhang Luteng,Sun Wan,Bu Shanshan,Pan Liangming,Tian Wenxi,Qiu Suizheng,Su G.H.,Wu Xinghua,Wang Xiaoyu 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.11

        Blanket is of vital importance for engineering application of the fusion reactor. Nuclear heat deposition in materials is the main heat source in blanket structure. In this paper, the three-dimensional method for thermalhydraulics/ neutronics coupling analysis is developed and applied for the full-scale module of the helium-cooled ceramic breeder tritium breeding blanket (HCCB TBB) designed for China Fusion Engineering Test Reactor (CFETR). The explicit coupling scheme is used to support data transfer for coupling analysis based on cell-to-cell mapping method. The coupling algorithm is realized by the user-defined function compiled in Fluent. The threedimensional model is established, and then the coupling analysis is performed using the paralleled Coupling Analysis of Thermal-hydraulics and Neutronics Interface Code (CATNIC). The results reveal the relatively small influence of the coupling analysis compared to the traditional method using the radial fitting function of internal heat source. However, the coupling analysis method is quite important considering the nonuniform distribution of the neutron wall loading (NWL) along the poloidal direction. Finally, the structure optimization of the blanket is carried out using the coupling method to satisfy the thermal requirement of all materials. The nonlinear effect between thermal-hydraulics and neutronics is found during the blanket structure optimization, and the tritium production performance is slightly reduced after optimization. Such an adverse effect should be thoroughly evaluated in the future work.

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