http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : Xiaoxin Zhu (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
Model-free predictive current control for IPMSMs with multiple current difference updating technique
Wu, Xiaoxin,Zhu, Zhihao,Liu, Xing,Yu, Feng The Korean Institute of Power Electronics 2021 JOURNAL OF POWER ELECTRONICS Vol.21 No.3
This paper proposes a model-free predictive current control (MFPCC) for interior permanent magnet synchronous motors (IPMSMs) with a multiple current difference updating (MCDU) technique. Firstly, to improve robustness against machine parameter variations and reduce the computational burden, current difference-based prediction that only requires accumulation operation is implemented, which avoids the model-based complex calculations in traditional model predictive current control (MPCC). Secondly, a MCDU technique is conducted with the characteristic of updating the current differences associated with voltage vectors in opposite directions. Thus, the updating frequency of the current difference can be significantly increased. Finally, the effectiveness of the proposed method is verified by simulation and experimental results.
-
Zuo, Chaohui,Xia, Man,Liu, Jingshi,Qiu, Xiaoxin,Lei, Xiong,Xu, Ruocai,Liu, Hanchun,Li, Jianliang,Li, Yongguo,Li, Qinglong,Xiao, Hua,Hong, Yuan,Wang, Xiaohong,Zhu, Haizhen,Wu, Qunfeng,Burns, Michael,Li Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.1
Objectives: Intrahepatic recurrence is the major cause of death among patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) after curative surgical resection. Several approaches have been reported to decrease the recurrence rate. The objective of our study was to compare the clinical effects of transcatheter arterial chemoembolization (TACE) combined with interferon-alpha (IFN-${\alpha}$) therapy on recurrence after hepatic resection in patients with HBV-related HCC with that of TACE chemotherapy alone. Methods: We retrospectively analyzed the data from 228 patients who were diagnosed with HBV-related HCC and underwent curative resection between January 2001 to December 2008. The patients were divided into TACE (n = 126) and TACE-IFN-${\alpha}$ (n = 102) groups for postoperative chemotherapy. The TACE regimen consisted of 5-fluorouracil (5-FU), cisplatin (DDP), and the emulsion mixed with mitomycin C (MMC) and lipiodol. The recurrence rates, disease-free survival (DFS), overall survival (OS), and risk of recurrence were evaluated. Results: The clinicopathological parameters and adverse effects were similar between the 2 groups (P > 0.05). The median OS for the TACE-IFN-${\alpha}$ group (36.3 months) was significantly longer than that of the TACE group (24.5 months, P < 0.05). The 3-and 5-year OS for the TACE-IFN-${\alpha}$ group were significantly longer than those of the TACE group (P < 0.05) and the recurrence rate was significantly lower (P < 0.05). The TACE and IFN-${\alpha}$ combination therapy, active hepatitis HBV infection, the number of tumor nodules, microvascular invasion, liver cirrhosis, and the BCLC stage were independent predictors of OS and DFS. Conclusions: The use of the TACE and IFN-${\alpha}$ combination chemotherapy after curative hepatic resection safely and effectively improves OS and decreases recurrence in patients with HBV-related HCC who are at high risk. Our findings can serve as a guide for the selection of postoperative adjuvant chemotherapy for patients with HBV-related HCC who are at high risk of recurrence.
-
Zipeng Gong,Ying Chen,Ruijie Zhang,Qing Yang,Yajie Wang,Yan Guo,Bingbing Zhou,Xiaogang Weng,Xuchen Liu,Yujie Li,Xiaoxin Zhu,Yu Dong 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.10
Berberine is one of active alkaloids from Rhizomacoptidis in traditional Chinese medicine. The pharmacokineticsof berberine in rat plasma were compared betweennormal and chronic visceral hypersensitivity irritable bowelsyndrome rats (CVH-IBS) established by mechanical colonirritation using angioplasty balloons for 2 weeks after oraladministration of berberine hydrochloride (25 mg/kg) withthe equivalent dose of 22 mg/kg for berberine according tobody weight. Immunohistochemical analysis of c-fos andmyosin light chain kinase (MLCK) and immunofluorescenceanalysis of MLCK in rat colon were conducted. Quantificationof berberine in rat plasma was achieved by using a sensitiveand rapidUPLC-MS/MSmethod. Plasma samples werecollected at 15 different points in time and the pharmacokineticparameters were analyzed by WinNonlin software. Thegreat different pharmacokinetic behavior of berberine wasobserved between normal and CVH-IBS model rats. Compared with normal group, T1/2 and AUC(0–t) of berberinein the model group were significantly increased, respectively(573.21 ± 127.53 vs 948.22 ± 388.57 min; 8,657.19 ±1,562.54 vs 11,415.12 ± 1,670.72 min.ng/ml). Cl/F of berberinein the model group significantly decreased, respectively(13.89 ± 1.69 vs 9.19 ± 2.91 L/h/kg). Additionally,the expressions of c-fos and MLCK in model group werehigher than those in normal group. The pharmacokinetic behaviorof berberine was significantly altered in CVH-IBSpathological conditions, which indicated the dosage modificationof berberine hydrochloride in CVH-IBS were necessary. Especially, improved exposure to berberine in ratplasma inCVH-IBSmodel rats was attributed to increased theexpression of MLCK.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
