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Mocklinter : Linting Mutual Exclusive Deadlocks with Lock Allocation Graphs
Zhen Yu,Xiaohong Su,Tiantian Wang,Peijun Ma 보안공학연구지원센터 2016 International Journal of Hybrid Information Techno Vol.9 No.3
Deadlocks are serious runtime bugs and are difficult to expose, reproduce and diagnose. Once suffering from them, programs may be afflicted with increasing response time, decreasing throughputs, or even crashes. We present Mocklinter, a dynamic deadlock detection tool to capture a deadlock as soon as it happens and spit out enough information to support source-level debugging. Mocklinter tracks the synchronization state of the target program by dynamically constructing and maintaining a lock allocation graph. Mocklinter uses this graph to decide whether a deadlock is confronted or not. Mocklinter handles all types of pthread mutexes and can detect any number of deadlocks at a time. Each deadlock captured by Mocklinter can involve any number of threads. We implemented Mocklinter in Linux-3.2.0 and evaluated it with ten applications, including Dining-Philosophers, Sshfs, SQLite, OpenLDAP, MySQL and so on, whose sizes varies from 0.1K to 1021.0K in terms of LOC. The results demonstrate effectiveness against real or artificial deadlock bugs, while incurring modest performance overhead and scaling to more than one thousand of threads.
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Qingxiao Zhou,Yongliang Yong,Weiwei Ju,Xiangying Su,Xiaohong Li,Chaoyang Wang,Zhibing Fu 한국물리학회 2018 Current Applied Physics Vol.18 No.1
Dioxins are highly toxic to humans and environment, and developing the effective methods to control and detect the organic pollutant is particular important. Here we performed a density functional theory (DFT) study on the adsorption of 2, 3, 7, 8-tetrachlorodibenzofuran (TCDF) molecules on the modified graphene substrates. The results indicated that the introducing of vacancy-defect and dopants (Mn and Fe) significantly improves the sensitivity toward TCDF molecules. The impurity played a crucial role for interacting with TCDF molecules. Furthermore, the adsorption of TCDF induced band-gap open in defected graphene substrates, which could be seen as electric signal to detect TCDF pollutant. The present study is expected to be useful to explore effective materials to detect and remove dioxin pollutants based on graphene.
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Qingna Xu,Tongchao Ji,Qingfeng Tian,Yuhang Su,Liyong Niu,Xiaohong Li,Zhijun Zhang 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2018 NANO Vol.13 No.12
A series of silica surface-capped with hexamethyldisilazane (denoted as H-SiO2) were prepared by liquid-phase in-situ surface-modification method. The as-obtained H-SiO2 was incorporated into acrylic amino (AA) baking paint to obtain AA/H-SiO2 composite extinction paints and/or coatings. N2 adsorption–desorption tests were conducted to determine the specific surface area as well as pore size and pore volume of H-SiO2. Moreover, the effects of H-SiO2 matting agents on the physical properties of AA paint as well as the gloss and transmittance of AA-based composite extinction coatings were investigated. Results show that H-SiO2 matting agents possess a large specific surface area and pore volume than previously reported silica obtained by liquid-phase method. Besides, they have better dispersibility in AA baking paint than the unmodified silica. Particularly, H-SiO2 with a silica particle size of 6.7 μm and the dosage of 4% (mass fraction) provides an extinction rate of 95.2% and a transmittance of 79.3% for the AA-based composite extinction coating, showing advantages over OK520, a conventional silica matting agent. Along with the increase in the silica particle size, H-SiO2 matting agents cause a certain degree of increase in the viscosity of AA paint as well as a noticeable decrease in the gloss of the AA-based composite extinction coating, but they have insignificant effects on the hardness and adhesion to substrate of the AA-based composite coatings. This means that H-SiO2 matting agents could be well applicable to preparing low-viscosity and low-gloss AA-based matte coatings.
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Tian, Fengyuan,Huang, Shuo,Xu, Wangda,Chen, Lan,Su, Jianming,Ni, Haixiang,Feng, Xiaohong,Chen, Jie,Wang, Xi,Huang, Qi The Korean Society of Ginseng 2022 Journal of Ginseng Research Vol.46 No.6
Background: Incretin impairment, characterized by insufficient secretion of L-cell-derived glucagon-like peptide-1 (GLP-1), is a defining step of type 2 diabetes mellitus (T2DM). Ginsenoside compound K (CK) can stimulate GLP-1 secretion; however, the potential mechanism underlying this effect has not been established. Methods: CK (40 mg/kg) was administered orally to male db/db mice for 4 weeks. The body weight, oral glucose tolerance, GLP-1 secretion, gut microbiota sequencing, bile acid (BA) profiles, and BA synthesis markers of each subject were then analyzed. Moreover, TGR5 expression was evaluated by immunoblotting and immunofluorescence, and L-cell lineage markers involved in L-cell abundance were analyzed. Results: CK ameliorated obesity and impaired glucose tolerance in db/db mice by altering the gut microbiota, especially Ruminococcaceae family, and this changed microbe was positively correlated with secondary BA synthesis. Additionally, CK treatment resulted in the up-regulation of CYP7B1 and CYP27A1 and the down-regulation of CYP8B1, thereby shifting BA biosynthesis from the classical pathway to the alternative pathway. CK altered the BA pool by mainly increasing LCA and DCA. Furthermore, CK induced L-cell number expansion leading to enhanced GLP-1 release through TGR5 activation. These increases were supported by the upregulation of genes governing GLP-1 secretion and L-cell differentiation. Conclusions: The results indicate that CK improves glucose homeostasis by increasing L-cell numbers, which enhances GLP-1 release through a mechanism partially mediated by the gut microbiota-BA-TGR5 pathway. Therefore, that therapeutic attempts with CK might be useful for patients with T2DM.
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