Removal of Cs+, Sr2+, and Co2+ Ions from the Mixture of Organics and Suspended Solids Aqueous Solutions by Zeolites

Xiang-Hong Fang,Fang Fang,Chun-Hai Lu,Lei Zheng 한국원자력학회 2017 Nuclear Engineering and Technology Vol.49 No.3

Serving as an excellent adsorbent and inorganic ion exchanger in the water purification field, zeolite 4A has in this work presented a strong capability for purifying radioactive waste, such as Sr2+, Csþ, and Co2+ in water. During the processes of decontamination and decommissioning of suspended solids and organics in low-level radioactive wastewater, the purification performance of zeolite 4A has been studied. Under ambient temperature and neutral condition, zeolite 4A absorbed simulated radionuclides such as Sr2+, Csþ, and Co2+ with an absorption rate of almost 90%. Additionally, in alkaline condition, the adsorption percentage even approached 98.7%. After conducting research on suspended solids and organics of zeolite 4A for the treatment of radionuclides, it was found that the suspended clay was conducive to absorption, whereas the absorption of organics in solution was determined by the species of radionuclides and organics. Therefore, zeolite 4A has considerable potential in the treatment of radioactive wastewater.

Forming a thick CdZnTe epitaxial film by sublimating closely spaced

Xiang-Xiang Luoa,Cheng-Fang Qiao,Simon R Hall,Chun-Sheng Zhou 한양대학교 청정에너지연구소 2023 Journal of Ceramic Processing Research Vol.24 No.6

Thick Cadmium zinc telluride epitaxial films were grown on (100)GaAs substrate by Close-Spaced Sublimation. The growthrate was around 1 μm/min. SEM observations and XRD θ-2θ scan and ф scan revealed well-defined epitaxial features ofthe films. The films were found to be polycrystalline at the early stage of growth. As growth progressed, the films graduallybecame oriented until an epitaxial layer was formed. The polycrystalline to monocrystalline transition was achieved bypreferential lateral growth of the grains and with the aid of migration of atoms in the film. This growth mode differs fromthe well-established epitaxy where a suitable lattice fit is expected from the early stages of film growth. This mode can betterguide the growth mode of CZT thick films, and can grow large volume and high-quality thick films. High quality thick filmscan be better applied in fields such as solar cells, infrared and ultraviolet detection, and X-ray detection.

Genistein Improves the Major Depression through Suppressing the Expression of miR-221/222 by Targeting Connexin 43

Fang Shen,Wan-li Huang,Bao-ping Xing,Xiang Fang,Mei Feng,Chun-ming Jiang 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.10

Objective: Recent studies have indicated the possibility that genistein may improve depression via regulating the expression of miR-221/222. This study is to explore whether genistein could improve depression by altering miR-221/222 levels and investigate the possible mechanisms involved in the improvement effect of genistein. Methods: The animal model of depression was established through unpredictable chronic mild stress. Nest building test and splash test were adapted to evaluate the effects of genistein on depressive symptoms in mice. qRT-PCR and western blot analysis were used to detect the expression of miR-221/222 and connexin 43 (Cx43) in the prefrontal cortex of the mice. In vitro, U87-MG astrocytes were treated with genistein and the expression of miR-221/222 and Cx43 was measured. The dual-luciferase reporter assay was used to verify whether Cx43 was a direct target of miR-221/222. Results: The behavioral tests showed that genistein could significantly reduce depression symptoms of mice, and this remission was not affected by gender. Genistein in vivo and in vitro could reduce increased levels of miR-221 and miR-222 in the prefrontal cortex of depressed mice, while upregulate Cx43 expression. Dual-luciferase reporter assay suggested Cx43 was directly regulated by miR-221/222 in astrocytes. Conclusion: Genistein can play its antidepressant effect through down-regulating miR-221/222 by targeting Cx43.

Hydrothermal Synthesis, Crystal Structure and EPR Property of Tetranuclear Copper(II) Cluster [Cu4OCl6(C14H12N2)4]

Fang-fang Jian*,Pu-su Zhao,Huan-xiang Wang,Lu-de Lu 대한화학회 2004 Bulletin of the Korean Chemical Society Vol.25 No.5

은(I)화합물:비스(디프로필디싸이오포스페이토)비스(1,10-펜안트로린)이온(I);Ag₂[Phen]₂[S₂P(OPr)₂]₂

Fang Fang Jian,Hai Lian Xiao,Huan Xiang Wang,Kui Jiao Korean Chemical Society 2003 대한화학회지 Vol.47 No.1

이핵 화합물, $Ag_2$[Phen]_2[S_2P(OPr)_2]_2$(Phen=1,10-phenanthroline; Pr=propyl)은 비스(디프로필디싸이오포스페이토) 은(|)화합물과 1,10 펜안트로린 리간드 반응에 의하여 합성되었고, 그 화합물 구조는 X-ray에 의하여 규명되었다. 두 디프로필디싸이오포스페이토 리간드는 두 개의 은 원자를 연결하여 팔각형 $Ag_2S_4P_2$ 고리를 형성하였고, 1,10-펜안트로린 리간드는 은 이온과 결합하여 사면체구조를 이루었다. Ag-S 결합거리는 2.471(1)와 2.567(1) ${\AA}$이었고, Ag-N 결합 거리는 2.3666(3)와 2.471(3) ${\AA}$이었다. The dinuclear $Ag_2[Phen]_2[S_2P(OPr)_2]_2$(phen=1,10-phenanthroline; Pr=propyl), was prepared by the reaction of bis(dipropyldithiophosphato) silver(I) complex with 1,10-phenanthroline ligand, and its structure was determined by X-ray crystallography. The two dipropyldithiophosphato ligands each bridge two silver atoms to form an eight-membered $Ag_2S_4P_2$ ring, while the 1,10-phenanthroline molecule coordinates to a silver atom to complete the local tetrahedral geometry for the metal ion. The Ag-S bond distances are 2.559(1) and 2.567(1)${\AA}$, and the Ag-N bond distances are 2.366(3) and 2.471(3)${\AA}$.

Genistein Improves the Major Depression through Suppressing the Expression of miR-221/222 by Targeting Connexin 43

Fang Shen,Wan-li Huang,Bao-ping Xing,Xiang Fang,Mei Feng,Chun-ming Jiang 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.11

Objective Recent studies have indicated the possibility that genistein may improve depression via regulating the expression of miR- 221/222. This study is to explore whether genistein could improve depression by altering miR-221/222 levels and investigate the possible mechanisms involved in the improvement effect of genistein. Methods The animal model of depression was established through unpredictable chronic mild stress. Nest building test and splash test were adapted to evaluate the effects of genistein on depressive symptoms in mice. qRT-PCR and western blot analysis were used to detect the expression of miR-221/222 and connexin 43 (Cx43) in the prefrontal cortex of the mice. In vitro, U87-MG astrocytes were treated with genistein and the expression of miR-221/222 and Cx43 was measured. The dual-luciferase reporter assay was used to verify whether Cx43 was a direct target of miR-221/222. Results The behavioral tests showed that genistein could significantly reduce depression symptoms of mice, and this remission was not affected by gender. Genistein in vivo and in vitro could reduce increased levels of miR-221 and miR-222 in the prefrontal cortex of depressed mice, while upregulate Cx43 expression. Dual-luciferase reporter assay suggested Cx43 was directly regulated by miR-221/222 in astrocytes. Conclusion Genistein can play its antidepressant effect through down-regulating miR-221/222 by targeting Cx43.

Development of a Molecular Marker for Fruiting Body Pattern in Auricularia auricula-judae

( Fang-jie Yao ),( Li-xin Lu ),( Peng Wang ),( Ming Fang ),( You-min Zhang ),( Ying Chen ),( Wei-tong Zhang ),( Xiang-hui Kong ),( Jia Lu ),( Yoichi Honda ) 한국균학회 2018 Mycobiology Vol.46 No.1

The fruiting body pattern is an important agronomic trait of the edible fungus Auricularia auricula-judae, and an important breeding target. There are two types of fruiting body pattern: the cluster type and the chrysanthemum type. We identified the fruiting body pattern of 26 test strains, and then constructed two different near-isogenic pools. Then, we developed sequence characterized amplified region (SCAR) molecular markers associated with the fruiting body pattern based on sequence-related amplified polymorphism (SRAP) markers. Ten different bands (189-522 bp) were amplified using 153 pairs of SRAP primers. The SCAR marker “SCL-18” consisted of a single 522-bp band amplified from the cluster-type strains, but not the chrysanthemum strains. This SCAR marker was closely associated with the cluster- type fruiting body trait of A. auricula-judae. These results lay the foundation for further research to locate and clone genes controlling the fruiting body pattern of A. auricula-judae.

Acute Flaccid Myelitis: Current Status and Diagnostic Challenges

Xiang Fang,Ruksana Huda 대한신경과학회 2020 Journal of Clinical Neurology Vol.16 No.3

Acute flaccid myelitis (AFM) is a sudden-onset polio-like neuromuscular disability found commonly in young children. There is an increasing incidence of confirmed AFM cases in the USA and other countries in recent years, and in association with nonpolio enterovirus infection. This represents a significant challenge to clinicians and causes significant concern to the general public. Acute flaccid paralysis (AFP) is the long-known limb paralytic syndrome caused by a viral pathogen. AFM is a subset of AFP that is also characterized by a limb paralytic condition, but it has certain distinct features such as lesions in magnetic resonance imaging of the spinal cord gray matter. AFM leads to spinal cord, brainstem, or motor neuron dysfunction. The clinical phenotypes, pathology, and patient presentation of AFM closely mimic AFP. This article provides a concise overview of our current understanding of AFM and the clinical features that distinguish AFM from AFP and similar other neurological infectious and autoimmune diseases or disorders. We also discuss the diagnosis, clinical pathology, possible pathogenetic mechanisms, and currently available therapies.

일반논문 : 중국인 한국어 학습자를 위한 종성 /ㅇ/의 발음 교육 방안

방향옥 ( Xiang Yu Fang ) 조선대학교 인문학연구원 2009 인문학연구 Vol.37 No.-

본 연구는 중국어 화자들이 한국어의 학습에서 종성 /ㅇ/을 발음하는 데 있어서 오류를 보이는 현상을 바탕으로 연구가 이루어진 것이다. 연구에서는 외국어로서의 한국어 교재에서 종성 /ㅇ/ 발음의 교육 내용을 검토하고, 한국어 초급 학습자를 대상으로 종성 /ㅇ/의 발음을 네 가지 유형별로 나누어 실현율을 조사하며, 조사 결과를 토대로 오류분석을 펼치고 있다. 마지막으로 결론에서는 오류를 피할 수 있는 효과적인 /ㅇ/ 발음 교육 방안을 제시하고 있다. This essay is based on the Chinese students` pronunciation mistakes when they are enunciating Korean fulcrum /ㅇ/. The second chapter is a discussion about the fulcrum /ㅇ/ contents in Korean language text books for Chinese learners. In the fourth chapter, I analyzed the error, which the senior Korean learners made, by 4 types of fulcrum /ㅇ/. At last I found a program to avoid the error to the Chinese learners with effect.

Proteomic analysis of novel targets associated with TrkA-mediated tyrosine phosphorylation signaling pathways in SK-N-MC neuroblastoma cells

Wu, Fang-Xiang,Ressom, Habtom,Dunn, Michael J Blackwell Publishing Inc 2013 Proteomics Vol.13 No.2

<P>Tropomyosin-related kinase A (TrkA) is a receptor-type protein tyrosine kinase and exploits pleiotypic roles via nerve growth factor (NGF)-dependent or NGF-independent mechanisms in various cell types. Here, we showed that the inhibition of TrkA activity by GW441756 resulted in the suppression of tyrosine phosphorylation of cellular proteins including extracellular signal-regulated protein kinase (ERK) and c-Jun N-terminal kinase (JNK). To find novel targets associated with TrkA-mediated tyrosine phosphorylation signaling pathways, we investigated GW441756 effects on TrkA-dependent targets in SK-N-MC neuroblastoma cells by proteomic analysis. The major TrkA-dependent protein spots controlled by GW441756 were determined by PDQuest image analysis, identified by MALDI-TOF MS and MALDI-TOF/TOF MS/MS, and verified by 2DE/Western blot analysis. Thus, we found that most of the identified protein spots were modified forms in a normal condition, and their modifications were regulated by TrkA activity. Especially, our results demonstrated that the modifications of α-tubulin and heterogeneous nuclear ribonucleoproteins C1/C2 (hnRNP C1/C2) were significantly upregulated by TrkA, whereas α-enolase modification was downregulated by TrkA, and it was suppressed by GW441756, indicating that TrkA activity is required for their modifications. Taken together, we suggest here that the major novel TrkA-dependent targets such as α-tubulin, hnRNP C1/C2, and α-enolase could play an essential role in TrkA-mediated tyrosine phosphorylation signaling pathways via regulation of their posttranslational modifications.</P>