백혈병환자에서 Liposomal Amphotericin B로 치료된 파종성 Fusarium 감염 1예

이지연,김성범,박대원,신성희,김용현,윤소영,엄중식,최철원,정희진,김우주,김준석,김장수,이갑노 대한감염학회 2003 감염과 화학요법 Vol.35 No.5

Fusarium spp.는 사람에서 드물게 각막염, 조갑진균증, 상처나 화상부위감염 등을 유발하는 것으로 알려져 있으나 최근에는 면역저하자에서 기회감염의 원인균으로 증가하고 있는 추세이다. 면역저하자에서 파종성 감염이 있는 경우에 예후는 치명적이나, 증례가 많지 않고 진단방법이 제한되어 있어 조기 진단과 신속한 치료가 쉽지 않다. 그러나 특징적으로 피부병변의 동반이 흔하여 면역저하자에서는 피부 병변의 면밀한 관찰과 함께 Fusarium 감염을 조기에 의심하여 피부생검이나 배양을 하는 것이 진단에 도움이 되리라 생각된다. 파종성 Fusarium 감염의 치료로는 감염 부위의 국소적 외과적 절제와 전신적 항진균제의 사용이 필요하고 현재까지는 amphotericin B가 비교적 효율적인 항진균제로 알려져 있으나 면역저하자에서 이에 반응을 하지 않는 경우가 많다. 저자들은 급성골수성백혈병 환자에서 관해유도화학요법 시행 후 호중구감소상태에서 피부병변과 폐침윤이 발견되었고 피부의 중심부 궤양을 동반한 구진성 병변에서 배양검사를 통해 파종성 Fusarium 감염을 진단하였으며 liposomal amphotericin B (AmBisome )를 사용하여 성공적으로 치료한 예를 경험하여 보고하는 바이다. Fusarium spp., basically a superficial pathogen, is a newly emerging fungal pathogen of opportunistic infections in immunocompromised patients. At present, although Fusarium spp. are relatively resistant to amphotericin B, the combination of amphotericin B and surgical debridement appear to be optimal treatment for disseminated infection. Recently we experienced a 32-year-old neutropenic patient after induction chemotherapy for acute myelocytic leukemia presented with skin lesions and infiltrations in both lungs. We diagnosed with disseminated fusariosis by skin culture and successfully treated the patient with liposomal amphotericin B. We emphasize a high index of suspicion for skin lesions especially in immunocopromised patients.

Fly Ash를 사용한 수중 불분리 콘크리트의 배합 방법에 따른 콘크리트의 성질에 관한 연구

김우중,권중현 진주산업대학교 1997 論文集 Vol.36 No.-

This study investigates the effect of mixing method on the antiwashout underwater concrete containing Fly Ash. On the experimental condition, the unit weight of used materials was fixed and a new the mixing method different from the traditional method in its prolonged mixing time and the order of material inputs was used. In this experiment, the mixing time was prolonged to 10 minutes, and the order of material input was changed to make the admixture homogeneous. That method of mixing improved the fluidty, the unit weight and compressive strength of fresh concrete.

溫室保溫커튼의 材料特性에 따른 保溫效果分析

金榮福,金容換,李昇揆,金成泰,羅又禎,閔永鳳,朴重春,崔東烈 慶尙大學校 1991 論文集 Vol.30 No.2

The effects of the material properties of thermal curtains upon reduction of the greenhouse heat loss were studied. A theoretical analysis procedure with equations and computer programs was developed to estimate them by using energy balance principles. Curtain effectiveness for every three kinds pf value level of the material properties were studied and compared. The results of this study would be useful for the developent and management of greenhouse thermal curtains.

역순사전의 효용성

金祐重 대구효성가톨릭대학교 외국어문학연구소 1990 語文學硏究 Vol.3 No.-

국내 주요 호수의 육수학적 조사(4): 주암호

김범철,박주현,허우명,임병진,황길순,최광순,최종수 江原大學校 附設 環境硏究所 2001 環境硏究 Vol.18 No.-

In this study limnological characteristics of Lake Juam was surveyed from June 1993 to May 1994 in order to provides important information regarding water resources. Seschi disc transparency, epilimnetic chlorophyll a(chl-a), tatal nitrogen(TN), total phosphorus(TP) concentration and primary productivity were in the range of 2.0~4.5 m, 0.9~13.6 mgChl/㎥, 0.78~2.32N/l, 11~56 mgP/㎥, 270~2,160mgCm^(-2)day^(-1), respectively. On the basis of TP, Chl-a and Secchi disc depth, the trophic state of Lake Juam can be classified as mesotrophic lake. The phosphorus inputs from non-point sources are concentrated in heavy rain episodes during the monsoon season. As a result, phosphorus concentration are higher in summer than in winter. TP loading from the watershed were estimated to be 0.9 gPm^(-2)yr(-1), which correspond to a boundary of the critical loading (1.0 gPm^(-2)yr(-1), which correspond to a boundary of the critical loading (1.0 gPm^(-2)yr(-1)) for eutrophication. From the results of the algal assay, both phosphous and nitrogen act as limiting nutrients in algal growth. The seasonal succession of phytoplankton community structure in Lake Juam was similar to that observed in other temperate lakes. Diatoms(Asterionella formosa and Aulacoseira granulata var. angustissima) were dominant in spring and winter, cyanobacteria (Microcystis aeruginosa, M. sp. and M. viridis) were dominant in warm season. The organic carbon, nitrogen and phosphorus content of lake sediment were 9.5~14.0 mgC/g, 1.01~1.82 mgN/g, and 0.51~0.65 mgP/g, respectively. The allochthonous organic carbon loading from the watershed and autochthonous organic carbon loading by primary production of phytoplankton were determined to be 1,122 tC/yr and 6,718 tC/yr, respectively. To prevent eutrophication of Lake Juam, nutrient management of watershed should be focus on reduction of fertilizer application, proper treatment of manure, and conservation of topsoil as well as point source.

임상가검물과 파라핀 포매 조직에서 PCR법을 이용한 결핵균의 검출

김은중,최우순,황석연 대한의생명과학회 2000 Journal of biomedical laboratory sciences Vol.6 No.1

PCR을 이용한 임상가검물 중에서 보편화된 객담 이외에 미량의 각종 체액과 임상에서 많이 실시하지 않는 파라핀 포매 조직에서의 결핵균 검출을 실험하여 그 활용 가능성을 규명하고자 하였다. 임상가검물인 체액 65예는 항산성 염색과 배양검사, PCR을 실시하였고, 파라핀 포매 조직 50예는 항산성 염색과 병리조직학적 진단, PCR을 실시하여 다음과 같은 결론을 얻었다. 본 실험 검체 중 임상가검물인 체액에서 항산성 염색 음성인 검체 중 12.1%,배양검사에서 음성인 검체 중 3.7%에서 PCR양성의 결과를 보였고, 파라핀 포매 조직에서는 항산성 염색 음성인 검체 중 20.0%에서 PCR양성의 결과를 얻어 PCR이 민감도와 특이도가 높음을 확인할 수 있었다. This study has been carried out to investigate the sensitivity of polymerase chain reaction (PCR) method over conventional acid-fast bacilli (AFB) staining and/culture methods for the detection of Mycobacterium tuberculosis from trace body fluid and paraffin-embedded tissues (PET) specimens. A total of 65 cases were employed for the AFB staining and culture test, and a total of 50 cases were subjected to PCR and histopathological analysis. Among the specimen showing negative reaction to AFB staining, 12.1% were positive to PCR and 3.7% of the specimen representing negative result to culture test showed positive reaction to PCR. In addition, 20.0% of the specimen with AFB negative showed positive reaction to PCR. From these results, it could be concluded that PCR method overwhelms AFB staining and culture tests in sensitivity and specificity to .M. specificity to tuberculosis detection.

生理的 運動强度 設定에 關한 理論的 考察

金海中,尹宇相 慶熙大學校 體育科學大學 1990 體育科學論叢 Vol.- No.3

1. Optimum training intensity standardizing % VO₂max. In case of exercising with the object of improving physical fitness, 50% VO₂max level intensity is very effective and exercising with a few minute of training duration 70∼80% VO₂max level intensity is suitable. To get training effect, above 60% VO₂max level intensity must be done, aerobic capacity improve at 75% VO₂max level. Generally, 75∼85% VO₂max level is used in athletic events, and 85∼95% VO₂max level is used for long distance running. 2. Optimum training intensity standardizing % HRmax. Age differences must be taken into consideration in order to set up training intensity with % H. Rmax as it was and relative heart rate must be used. Teh range of training intenstity is 60 to 90% HRmax level. In general, the standard intensity is 70 to 90% HRmax level. 3. Optimum training intensity standardizing metabolic alternation. There are significant changes of VO₂max and AT???at AT level and above AT level, but no change in LT, AT at below AT level.

멕시코 문화 이해 교육 프로젝트 : 멕시코 진출업체 임직원용 연수 자료

김우중 대구효성가톨릭대학교 외국어문학연구소 1997 語文學硏究 Vol.9 No.-

직접강도법에 의한 축대칭 원추형 쉘의 단순화 해석

김우중,권중현,이관희 진주산업대학교 1997 論文集 Vol.36 No.-

The stress analysis concerned with axisymmetrically loaded axisymmetrical structures, such as pressure vessels, rockets, cooling towers, roof domes and storage tanks, has been researched with a lot of difficulties. The elements of revolution using the finite element method enable these problems to be analyzed with a high degree of confidence. This research focuses on the efficient conduct of the thin axisymmetric shells subject to axisymmetrical load which was idealized by a series of conical frustum-shaped elements that was suggested by Grafton and Strome and later extended by Percy. In this study, this research mentioned above is extended to the conical shell whose end is fixed to simplify the methodology of the analysis of any kinds of axisymmetrically loaded axisymmetrical shell structures. To demonstrate the validity and simplicity, the results of the proposed method were compared with the numerical solution SAP90 and got agreeable results.

Maxico 市 敎養 階層의 使用 語彙 調査 : 身體 및 家族 關聯 語彙를 中心으로 Sobre el cuerpo humano y la familia

金祐重 대구효성가톨릭대학교 외국어문학연구소 1988 語文學硏究 Vol.1 No.-

본 조사 자료는 1964년 8월 2일부터 8월 8일까지 Bloomington에서 개최된 중남미 언어학 및 언어 교육 기획단 산하 중남미 언어학 위원회의 제2차 심포지움에서 결정한 바 있는 "중남미 주요 도시의 교식 계층의 언어 사용 행태 연구 계획"의 일환으로 상기 위원회의 계획 집행 소위원회가 Mexico시에서 1972년~1973년에 걸쳐 행한 설문 조사의 결과이다.