Safety Management Documentation Models for the Maritime Labour Convention, 2006

Wen-jen WU,Don Jyh-Fu JENG 한국해운물류학회 2012 The Asian journal of shipping and Logistics Vol.28 No.1

The Maritime Labour Convention, 2006 (MLC, 2006), which will enter into force in 2012 or 2013, focuses on seafarers’ rights, safety and health in order to promote a better shipping environment. A Declaration of Maritime Labour Compliance Part II (DMLC II) is required to state the measures taken to ensure the quality of seafarers’ living and working conditions on-board a ship. It is a challenge for ship owners to establish such a document and fit it into the existing safety management systems, International Safety Management Code (ISM). This paper proposes four possible documentation models of the ship owners’ management system to cover the DMLC II with pros and cons. An appropriate documentation model not only benefits owners with regard to enforcement of the MLC, 2006, but also helps the flag and port state administrations to perform effective and efficient inspections.

Enhancement of Aggregation-Induced Emission in Dye-Encapsulating Polymeric Micelles for Bioimaging

Wu, Wen-Chung,Chen, Ching-Yi,Tian, Yanqing,Jang, Sei-Hum,Hong, Yuning,Liu, Yang,Hu, Rongrong,Tang, Ben Zhong,Lee, Yi-Ting,Chen, Chin-Ti,Chen, Wen-Chang,Jen, Alex K.-Y. WILEY-VCH Verlag 2010 Advanced Functional Materials Vol.20 No.9

<P>Three amphiphilic block copolymers are employed to form polymeric micelles and function as nanocarriers to disperse hydrophobic aggregation-induced emission (AIE) dyes, 1,1,2,3,4,5-hexaphenylsilole (HPS) and/or bis(4-(N-(1-naphthyl) phenylamino)-phenyl)fumaronitrile (NPAFN), into aqueous solution for biological studies. Compared to their virtually non-emissive properties in organic solutions, the fluorescence intensity of these AIE dyes has increased significantly due to the spatial confinement that restricts intramolecular rotation of these dyes and their better compatibility in the hydrophobic core of polymeric micelles. The effect of the chemical structure of micelle cores on the photophysical properties of AIE dyes are investigated, and the fluorescence resonance energy transfer (FRET) from the green-emitting donor (HPS) to the red-emitting acceptor (NPAFN) is explored by co-encapsulating this FRET pair in the same micelle core. The highest fluorescence quantum yield (∼62%) could be achieved by encapsulating HPS aggregates in the micelles. Efficient energy transfer (>99%) and high amplification of emission (as high as 8 times) from the NPAFN acceptor could also be achieved by spatially confining the HPS/NPAFN FRET pair in the hydrophobic core of polymeric micelles. These micelles could be successfully internalized into the RAW 264.7 cells to demonstrate high-quality fluorescent images and cell viability due to improved quantum yield and reduced cytotoxicity.</P> <B>Graphic Abstract</B> <P>Highly efficient fluorescence probes are achieved through the encapsulation of aggregation-induced emission molecules, 1,1,2,3,4,5-hexaphenylsilole (HPS) and/or bis(4-(N-(1-naphthyl) phenylamino)-phenyl)fumaronitrile (NPAFN) in the core of polymeric micelles. Bright fluorescence cell images are shown with tunable colors of green directly from HPS aggregates and red through efficient fluorescence resonance energy transfer (FRET) from HPS aggregates to NPAFN aggregates. <img src='wiley_img_2010/1616301X-2010-20-9-ADFM200902043-content.gif' alt='wiley_img_2010/1616301X-2010-20-9-ADFM200902043-content'> </P>

Comparison of Short- and Long-term Hearing Outcomes of Successful Inlay Cartilage Tympanoplasty Between Small and Large Eardrum Perforations

Pei-Wen Wu,Wen-Hung Wang,Chi-Che Huang,Ta-Jen Lee,Chien-Chia Huang 대한이비인후과학회 2015 Clinical and Experimental Otorhinolaryngology Vol.8 No.4

Objectives. To compare the short- and long-term hearing outcomes after successful inlay cartilage tympanoplasty between patients with small (≤25%) and large (≥50%) eardrums perforations. Methods. This is a retrospective case series study conducted in a tertiary referral center. Twenty-five patients who underwent 27 procedures were enrolled. Their mean age was 60.26 years (range, 42 to 76 years). The mean follow-up time was 18.86 months (range, 12.30 to 35.83 months). The preoperative, initial postoperative, and long-term hearing results in patients with total repair of the eardrum were analyzed. Results. In the small size group, the average (±standard deviation) air-bone gap (ABG) closure was 1.08±7.53 dB in the short-term and 2.33±11.56 dB in the long-term hearing examinations. There was no difference between short- and long-term ABG closure (P=0.689). In the large size group, the average ABG closure was 9.77±9.40 dB in the short-term and 16.25±6.01 dB in the long-term hearing examinations. There was a significant difference between short- and long-term ABG closure (P=0.029). Conclusion. Patients with large perforations have continuous hearing improvement and ABG closure for more than one year. In contrast, the short- and long-term postoperative ABGs are almost the same in patients with small perforations. More long-term postoperative follow-up of hearing results is necessary for large perforations.

On-line Robust Control of a System with Dead Time

Wen-Teng Wu,Yu-Jen Jang 제어로봇시스템학회 1990 제어로봇시스템학회 국내학술대회 논문집 Vol.1990 No.10

On-Line Robust Control of a System with Dead Time

Wen Teng Wu,Yu Jen Jang 대한전자공학회 1990 대한전자공학회 학술대회 Vol.1990 No.01

Meta-analysis of genome-wide association studies in East Asian-ancestry populations identifies four new loci for body mass index

Wen, Wanqing,Zheng, Wei,Okada, Yukinori,Takeuchi, Fumihiko,Tabara, Yasuharu,Hwang, Joo-Yeon,Dorajoo, Rajkumar,Li, Huaixing,Tsai, Fuu-Jen,Yang, Xiaobo,He, Jiang,Wu, Ying,He, Meian,Zhang, Yi,Liang, Jun IRL Press 2014 Human molecular genetics Vol.23 No.20

<P>Recent genetic association studies have identified 55 genetic loci associated with obesity or body mass index (BMI). The vast majority, 51 loci, however, were identified in European-ancestry populations. We conducted a meta-analysis of associations between BMI and ∼2.5 million genotyped or imputed single nucleotide polymorphisms among 86 757 individuals of Asian ancestry, followed by <I>in silico</I> and <I>de novo</I> replication among 7488–47 352 additional Asian-ancestry individuals. We identified four novel BMI-associated loci near the <I>KCNQ1</I> (rs2237892, <I>P</I> = 9.29 × 10<SUP>−13</SUP>), <I>ALDH2/MYL2</I> (rs671, <I>P</I> = 3.40 × 10<SUP>−11</SUP>; rs12229654, <I>P</I> = 4.56 × 10<SUP>−9</SUP>), <I>ITIH4</I> (rs2535633, <I>P</I> = 1.77 × 10<SUP>−10</SUP>) and <I>NT5C2</I> (rs11191580, <I>P</I> = 3.83 × 10<SUP>−8</SUP>) genes. The association of BMI with rs2237892, rs671 and rs12229654 was significantly stronger among men than among women. Of the 51 BMI-associated loci initially identified in European-ancestry populations, we confirmed eight loci at the genome-wide significance level (<I>P</I> < 5.0 × 10<SUP>−8</SUP>) and an additional 14 at <I>P</I> < 1.0 × 10<SUP>−3</SUP> with the same direction of effect as reported previously. Findings from this analysis expand our knowledge of the genetic basis of obesity.</P>

Light-Emitting Diode-Assisted Narrow Band Imaging Video Endoscopy System in Head and Neck Cancer

Hsin-Jen Chang,Wen-Hung Wang,Yen-Liang Chang,Tzuan-Ren Jeng,Chun-Te Wu,Ludovic Angot,Chun-Hsing Lee,Pa-Chun Wang 대한소화기내시경학회 2015 Clinical Endoscopy Vol.48 No.2

Background/Aims: To validate the effectiveness of a newly developed light-emitting diode (LED)-narrow band imaging (NBI) system for detecting early malignant tumors in the oral cavity. Methods: Six men (mean age, 51.5 years) with early oral mucosa lesions were screened using both the conventional white light and LED-NBI systems. Results: Small elevated or ulcerative lesions were found under the white light view, and typical scattered brown spots were identified after shifting to the LED-NBI view for all six patients. Histopathological examination confirmed squamous cell carcinoma. The clinical stage was early malignant lesions (T1), and the patients underwent wide excision for primary cancer. This is the pilot study documenting the utility of a new LED-NBI system as an adjunctive technique to detect early oral cancer using the diagnostic criterion of the presence of typical scattered brown spots in six high-risk patients. Conclusions: Although large-scale screening programs should be established to further verify the accuracy of this technology, its lower power consumption, lower heat emission, and higher luminous efficiency appear promising for future clinical applications.

Increasing the Lifetime of Ad Hoc Networks Using Hierarchical Cluster-based Power Management

( Tin-yu Wu ),( Kai-hua Kuo ),( Hua-pu Cheng ),( Jen-wen Ding ),( Wei-tsong Lee ) 한국인터넷정보학회 2011 KSII Transactions on Internet and Information Syst Vol.5 No.1

One inevitable problem in Ad Hoc networks is the limited battery capacity, which explains why portable devices might shut down suddenly when the power of hardware is depleted. Hence, how to decrease the power consumption is an important issue in ad hoc networks. With the development of wireless technology, mobile devices can transmit voices, surf the Internet, download entertaining stuffs, and even support some P2P applications, like sharing real-time streaming. In order to keep the quality stable, the transmission must be continuous and it is thus necessary to select some managers to coordinate all nodes in a P2P community. In addition to assigning jobs to the staffs (children) when needed, these managers (ancestors) are able to reappoint jobs in advance when employees retire. This paper proposed a mechanism called Cluster-based Power Management (CPM) to stabilize the transmissions and increase Time to Live (TTL) of mobile hosts. In our new proposed method, we establish the clusters according to every node`s joining order and capability, and adjust their sleep time dynamically through three different mathematical models. Our simulation results reveal that this proposed scheme not only reduces the power consumption efficiently, but also increases the total TTLs evidently.

Clinical Features of Patients with Esophageal and Second Primary Cancers

Tsai, Huang-Wen,Chang, Chih-Chun,Sun, Jen-Tang,Liou, Ching-Biau,Lin, Hsiu-Chen,Lin, I-Hsin,Yu, Yun-Chieh,Weng, Wei-Ling,Leong, Ka-I,Yen, Tzung-Hai,Wu, Jiann-Ming Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: The prevalence of esophageal cancer (EC) with second primary cancers (SPC) is increasing worldwide. This study was aimed to understand the clinical features of EC patients with SPC in the Taiwanese population. Materials and Methods: Clinical and laboratory data for 180 EC patients with or without SPC were collected between January 2009 and December 2013. Information on treatment approaches, location of SPCs and ABO blood type were also collected and stratified. Results: The most common SPC in EC patients was hypopharyngeal cancer, followed by laryngeal cancer and hepatocellular carcinoma in our study. Malignancies of colon, prostate and lung were also found. There was a significant higher portion of blood type A in the EC patients with SPC compared with those without (42.4% vs 19.5%, P=0.006). Conclusions: The frequency and SPC site distribution and blood type A should be considered in clinical evaluation of EC patients with a high risk of developing SPC in the Taiwanese population.

NEW RESULTS ON THE PSEUDOREDUNDANCY

Greferath, Marcus,Liu, Zihui,Wu, Xin-Wen,Zumbragel, Jens Korean Mathematical Society 2019 대한수학회보 Vol.56 No.1

The concepts of pseudocodeword and pseudoweight play a fundamental role in the finite-length analysis of LDPC codes. The pseudoredundancy of a binary linear code is defined as the minimum number of rows in a parity-check matrix such that the corresponding minimum pseudoweight equals its minimum Hamming distance. By using the value assignment of Chen and Kløve we present new results on the pseudocodeword redundancy of binary linear codes. In particular, we give several upper bounds on the pseudoredundancies of certain codes with repeated and added coordinates and of certain shortened subcodes. We also investigate several kinds of k-dimensional binary codes and compute their exact pseudocodeword redundancy.