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      • 간호대학생의 이론・실습 성적과 임상수행능력의 관련성 : 성인간호학 교과목을 중심으로

        권현진,김다영,김민정,김소현,박예담,박지원,왕서현,유영주,이재현,주가은,신수진 이화여자대학교간호학회 2020 이화간호학회지 Vol.- No.54

        Purpose: This study aimed to explore the relationship among score of theory course, score of practicum course and clinical practice ability by the course, Adult Health Nursing. Methods: A descriptive research was conducted using questionaries. Data were collected from September 25 to October 2, 2019. Participants were 67 nursing students at one university in Seoul on their junior year who have experienced clinical settings. The collected data were analyzed by t-test, ANOVA, Cohen’s Kappa, and Scheffe’s test using SPSS 25.0 version program. Results: Participants were given a quartile number from 1 to 4 respectively according to their scores of theory course those of practicum course. The total mean score of clinical practice ability was 3.61, with a perfect score of 5. The scores of theory course and practicum course showed slight correlation(Cohen’s Kappa=.168). However, significant correlation did not existed among score of theory course, score of practicum course and clinical practice ability. Conclusion: The result showed that score of theory course, score of practicum course and clinical practice ability have no significant correlation. However, its finding suggests the necessity of further research about various approach and new evaluation methods needed in order to improve nursing students’ competency.

      • SCIESCOPUSKCI등재

        The Expression of Porcine Adiponectin and Stearoyl Coenzyme a Desaturase Genes in Differentiating Adipocytes

        Wang, P.H.,Ko, Y.H.,Liu, B.H.,Peng, H.M.,Lee, M.Y.,Chen, C.Y.,Li, Y.C.,Ding, S.T. Asian Australasian Association of Animal Productio 2004 Animal Bioscience Vol.17 No.5

        The gene expression of porcine adiponectin and stearoyl coenzyme A desaturase (SCD) was investigated in this study. The partial gene sequences for adiponectin and SCD were amplified by RT-PCR from subcutaneous adipose tissue and cloned by TA cloning techniques. Sequences of these genes were determined and found to be highly homologous to that of other species, suggesting similar function of these genes as in other species. The transcripts of these adipocyte-related genes in pig tissues were measured by Northern analysis. The transcripts for adiponectin and SCD were highly expressed in porcine subcutaneous adipose tissue; the transcripts for SCD were also barely detected in the liver, but the greatest concentrations were in the adipose tissue. In porcine stromalvascular cells (S/V cells) cultured in vitro, transcripts for adiponectin and SCD increased gradually during adipocyte differentiation. The level of adipocyte adiponectin mRNA was associated with late adipocyte differentiation, indicating the gene may not be involved in adipocyte differentiation but has great importance in porcine adipocyte functions. The SCD transcripts were not detectable until 2 d after induction of adipocyte differentiation. It was highly expressed in differentiating porcine adipocytes (2 to 10 d after the induction of adipocyte differentiation), indicating a significant role of SCD in adipocytes.

      • 대학생의 외모에 대한 사회문화적 태도, 외모 스트레스와 섭식장애의 관계

        김민지,박민정,박예진,안슬기,왕소여,이소정,이지수,정은기,하효정,김건희 이화여자대학교간호학회 2020 이화간호학회지 Vol.- No.54

        Purpose: The purpose of this study is to verify the relationship between sociocultural attitudes towards appearance, appearance stress and eating disorders. Method: Sociocultural Attitudes Towards Appearance Questionnaire-4 revised which was translated to Korean measured sociocultural attitudes towards appearance and appearance stress measurement examined appearance stress. Korean Version of Eating Attitude Test-26 was used to measure eating disorders. 120 university students in a city took surveys from September 20 to October 8, 2019. Of the 120 questionnaires, 4 has insincere or incomplete responses and 116 questionnaires resulted in data. The questionnaires were investigated using statistical process of t-test, ANOVA, and Pearson's correlation coefficients using SPSS/Win 25.0 software package. Results: The average of KEAT-26 scores was 7.45 and the prevalence of eating disorders was 6.89% in the study. In eating disorders, there were significant differences according to subjective body image and diet experience. Eating disorders were positively correlated to sociocultural attitudes towards appearance (r=.21, p=.018) and appearance stress (r=.23, p=.006). Conclusion: This study verified the relationship between sociocultural attitudes towards appearance, appearance stress and eating disorders of university students, and expected to be supporting documents to develop programs for helping university students with eating disorders.

      • SCIESCOPUSKCI등재

        Cloning of Chicken Microsomal Glutathione S-transferase 1 Gene (MGST1) and Identification of Its Different Splice Variants

        Wang, X.-T.,Zhang, H.,Zhao, C.-J.,Li, J.-Y.,Xu, G.-Y.,Lian, L.-S.,Wu, C.-X.,Deng, Xuemei Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.2

        Mammal microsomal glutathione transferase 1 (MGST1) can conjugate many toxic or carcinogenic substances and depress oxidative stress. In this study, Chicken MGST1 and its variants were cloned for the first time and were composed of 956 or 944 nucleotides. The 12 nt deletion in the exon 2 did not alter the GT-AG rule and the ORFs for the two MGST1 variants were the same, which both comprised 465 nucletides and encoded a peptide with 155 amino acids. It was found that the two different splice variants identified using RT-PCR expressed in all three organs investigated of Dwarf Brown Chicken, namely liver, spleen and shell gland. Moreover, the expression level of MGST1 mRNA in the liver of Dwarf Brown chickens was the highest (p<0.01), and there were no significant differences between the spleen and the shell gland. These results provide a base for studying the biological function of Chicken MGST1.

      • 의학 비의학 전공 학생들의 Social Communication Network 분석 : 소집단 활동별 성분 측정

        김수연,김혜숙,왕영미,정미라,조미형,황승옥 이화여자대학교 의과대학 1979 梨花醫學誌 Vol.- No.11

        This study analyzed the Social Communication Network between medical students and non-medical students. The aim of this study is to help medical students to be better equipped to overcome hardship by understanding other students' relations. The results may be summurized as follows. (1) Opinion Leader. Non-medical students group had more opinion leaders on the part of Friends and Study than medical students group. Therefore, We could find that non-medical students group was more sociable and its association group work was stronger than medical students group But there was little difference in the part of Fashion. (2) Isolation As the result from investigating the ratio of students whose communication matrix were zero, we came to find that the ratio of medical students group was higher than that of nonmedical students group. So, medical students were more selfish and isolated particularly in the part of Fashion and Study there were wide difference. (3) Connectedness By the study of connectedness index, we found that non-medical students group's cohesiveness was very strong. (4) Integrativeness Intergrativeness index of non-medical students group was also high. In other words, medical students were more selfish and poor in forming group It was proved that there was evident difference in Social Communication Network between medical students group and non-medical students group, regarding to each of parts.

      • Two S-wave gap symmetry for single crystals of the superconductor BaFe<sub>1.8</sub>Co<sub>0.2</sub>As<sub>2</sub>

        Choi, K.Y.,Kim, S.H.,Choi, C.,Jung, M.H.,Wang, X.F.,Chen, X.H.,Noh, J.D.,Lee, S.I. North-Holland 2010 Physica. C, Superconductivity Vol.470 No.suppl1

        To clarify the gap structure of the iron-pnictide superconductors, we synthesized optimally doped single crystals of BaFe<SUB>1.8</SUB>Co<SUB>0.2</SUB>As<SUB>2</SUB>, which had a critical temperature, T<SUB>c</SUB>, of 23.6K. The initial M-H curve was used to find the lower critical field, H<SUB>c1</SUB>. The full range of the temperature dependence of H<SUB>c1</SUB> was explained by using a two S-wave gap symmetry. We estimate the two gap as Δ<SUB>1</SUB>(0)=1.64+/-0.2meV for the small gap and Δ<SUB>2</SUB>(0)=6.20+/-0.2meV for the large gap.

      • 고환종양 : 21례에 대한 임상 및 병리조직학적 고찰 Analysis of 21 Cases and Review of Literatures

        조정실,노재윤,김지환,이유복,김동식,최승강,이진무,왕종순 中央醫學社 1973 中央醫學 Vol.24 No.3

        Clinicopathological study was made on 21 testis tumors that were obtained during a period of 12 years, from 1960 to 1971, at the Department of Pathology and Urology, Yonsei University. The 21 cases of testis tumor are consisted of 18 malignant and 3 benign tumors and are classified histologically into 7 seminomas, 8 embryonal carcinomas, 3 teratomas, 1 reticulum cell sarcoma, 1 rhabdomyosarcoma, and I gonadoblastoma. The mean age is 24.7 years, and 36.4 years in seminoma, 15 years in embryonal carcinoma, 17.7 years in teratoma, and 33 years in miscellaneous. The tumors occurred more frequently in the right than the left. There's no bilateral occurrence. The most frequent clinical complaint was painful palpable mass which were present in 6 cases out of 10 cases. One case of seminoma is arisen from intraabdominal testis which seems frequently to precipitate tumor occurrence. The other notable case is gonadoblastoma arisen in dysgenetic testis of true hermaphroditism.

      • SCISCIESCOPUS

        Disruption of a regulatory loop between DUSP1 and p53 contributes to hepatocellular carcinoma development and progression

        Hao, P.P.,Li, H.,Lee, M.J.,Wang, Y.P.,Kim, J.H.,Yu, G.R.,Lee, S.Y.,Leem, S.H.,Jang, K.Y.,Kim, D.G. Elsevier Science Publishers 2015 Journal of hepatology Vol.62 No.6

        Background & Aims: Altered expression of dual specificity phosphatase 1 (DUSP1) is common in tumors including hepatocellular carcinoma (HCC), and is predictive of tumor progression and poor prognosis. However, the tumor suppressive role of DUSP1 has yet to be clearly elucidated. Methods: The molecular mechanisms of tumor suppression that were investigated were induction of apoptosis, cell cycle inhibition, and regulation of p53. Additionally, the antitumor effect of DUSP1 was assessed using a mouse model. Associated signaling pathways in HCC cells and tissues were examined. Results: Downregulation of DUSP1 expression was significantly correlated with poor differentiation (p<0.001) and advanced HCC stage (p=0.023). DUSP1 expression resulted in HCC suppression and longer survival (p=0.0002) in a xenoplant mice model. DUSP1 inhibited p38 MAPK phosphorylation and subsequently suppressed HSP27 activation, resulting in enhanced p53 phosphorylation at sites S15, S20, and S46 in HCC cells. Enhanced p53 activation induced the expression of target genes p21 and p27, which are linked to cell cycle arrest and apoptosis. Thus, DUSP1 was potentially linked to p53 activation via the p38 MAPK/HSP27 pathway. Wild-type but not mutant p53 transcriptionally upregulated DUSP1 via its DNA-binding domain. DUSP1 and p53 might collaborate to suppress tumors in hepatocarcinogenesis via a positive regulatory loop. Conclusions: Our results revealed that disruption of a positive regulatory loop between DUSP1 and p53 promoted HCC development and progression, providing a rationale for a therapeutic agent that restores DUSP1 in HCC.

      • KCI등재SCOPUS
      • 工業系高等學校의 視聽覺敎育 實態分析과 그 改善方案에 關한 硏究

        王鎭錫,吳承燁,朴東徹,林在鳳 충남대학교 공업교육연구소 1979 論文集 Vol.2 No.2

        From the investigation of the records regarding audiovisual education and answers to questionnaires received, it appears urgent to improve the problem on audio-visual education in technical high schools as follows: 1. The provincial boards of education should give added financial suppart to technical high schools for audio-visual education. 2. Audio-visual committees should be formed for audio -visual education in each technical high school. 3. Each teachnical high school should have an A-V center and a teacher in charge of A-V equipment. 4. All teachers including the teachers in charge should have qualified training in the use of A-V equipment. 5. An organization producing audio-visual materials suitable to technical high school should be composed.

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