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Dimension reduction and classification in ECG signal interpretation using FA & PCA: A comparison
VARUN GUPTA,MONIKA MITTAL 장전수학회 2018 Proceedings of the Jangjeon mathematical society Vol.21 No.4
Electrocardiogram (ECG) is the electrical activity of the heart. It consists of P-wave, QRS complex and T-wave. Each beat shows electrical impulse propagation in the heart of the body. Due to higher dimension of ECG signal, its analysis needs dimension reduction tech- niques for pre-processing of the data. In this paper, authors proposed Factor Analysis (FA) and Principal Component Analysis (PCA) for re- ducing dimension of the ECG signal. The choice of its usage depends on problem which is clearly known and specied. Physionet ECG data- base (MIT-BIH long term ECG database, Ventricular Tachyarrhythmia, AHA(American Heart Association) Database) and real time ECG data- base has been used in this paper for checking detector performance using FA and PCA. PCA gave better results than FA. SNR (Signal to Noise Ratio) is also checked and calculated that is 93.25 dB and 91.25 dB for PCA and FA respectively. Dierent work proposed by dierent authors on ECG signal classification has been compared.
Varun Katiyar,Ankit Gupta,Abdelouahed Tounsi 국제구조공학회 2022 Steel and Composite Structures, An International J Vol.45 No.5
In the present article, the vibration response of a geometrically imperfect bi-directional functionally graded plate (2D-FGP) with geometric discontinuities and micro-structural defects (porosities) has been investigated. A porosity model has been developed to incorporate the effective material properties of the bi-directional FGP which varies in two directions i.e. along the axial and transverse direction. The geometric discontinuity is also introduced in the plate in the form of a circular cut-out at the center of the plate. The structural kinematic formulation is based on the non-polynomial trigonometric higher-order shear deformation theory (HSDT). Finite element formulation is done using C° continuous Lagrangian quadrilateral four-noded element with seven degrees of freedom per node. The equations of motion have been derived using a variational approach. Convergence and validation studies have been documented to confirm the accuracy and efficiency of the present formulation. A detailed investigation study has been done to evaluate the influence of the circular cut-out, geometric imperfection, porosity inclusions, partial supports, volume fraction indexes (along with the thickness and length), and geometrical configurations on the vibration response of 2D-FGP. It is concluded that after a particular cut-out dimension, the vibration response of the 2D FGP exhibits non-monotonic behavior.
Clinical spectrum of elderly-onset inflammatory bowel disease in India
Yogesh Kumar Gupta,Arshdeep Singh,Vikram Narang,Vandana Midha,Ramit Mahajan,Varun Mehta,Dharmatma Singh,Namita Bansal,Madeline Vithya Barnaba Durairaj,Amit Kumar Dutta,Ajit Sood 대한장연구학회 2023 Intestinal Research Vol.21 No.2
Background/Aims: Inflammatory bowel disease (IBD) is increasingly being recognized in elderly patients. Data on clinical spectrum of elderly-onset IBD patients is lacking from India. Methods: A cross-sectional retrospective analysis of a prospectively maintained database of patients diagnosed with IBD was conducted at 2 centers in India. The clinical spectrum of elderly-onset IBD including demographic profile (age and sex), clinical presentation, disease characteristics (disease behavior and severity, extent of disease), and treatment were recorded and compared with adult-onset IBD. Results: During the study period, 3,922 (3,172 ulcerative colitis [UC] and 750 Crohn’s disease [CD]) patients with IBD were recorded in the database. A total of 186 patients (4.74%; 116 males [62.36%]) had elderly-onset IBD (69.35% UC and 30.64% CD). Diarrhea, blood in stools, nocturnal frequency and pain abdomen were the commonest presentations for UC, whereas pain abdomen, weight loss and diarrhea were the most frequent symptoms in CD. For both elderly onset UC and CD, majority of the patients had moderately severe disease. Left-sided colitis was the commonest disease location in UC. Isolated ileal disease and inflammatory behavior were the most common disease location and behavior, respectively in CD. 5-Aminosalicylates were the commonest prescribed drug for both elderly onset UC and CD. Thiopurines and biologics were used infrequently. Prevalence of colorectal cancer was higher in elderly onset IBD. Conclusions: Elderly onset IBD is not uncommon in India. Both the elderly onset UC and CD were milder, with no significant differences in disease characteristics (disease extent, location and behavior) when compared to adult-onset IBD. Colorectal cancer was more common in elderly onset IBD.
Clinical profile and outcomes of opioid abuse gastroenteropathy: an underdiagnosed disease entity
( Ramit Mahajan ),( Yogesh Gupta ),( Arshdeep Singh ),( Pulkit Dhiman ),( Vandana Midha ),( Chandan Kakkar ),( Vikram Narang ),( Varun Mehta ),( Kavita Saggar ),( Ajit Sood ) 대한장연구학회 2020 Intestinal Research Vol.18 No.2
Background/Aims: Opioid-induced bowel dysfunction includes nausea, vomiting, constipation and abdominal distension. We describe patients presenting with gastrointestinal (GI) ulcers and ulcerated strictures secondary to opioid abuse, an entity not well described in literature. Methods: This retrospective observational study included patients with opioid abuse gastroenteropathy presenting to Dayanand Medical College and Hospital, Ludhiana, India between January 2013 and December 2018. Opioid abuse gastroenteropathy was defined as gastric or small bowel ulcers and ulcerated strictures in patients abusing opioids, where all other possible etiologies of GI ulcers/strictures were excluded. Clinical, biochemical, endoscopic, radiological and histological parameters as well as response to treatment were assessed. Results: During the study period, 20 patients (mean age, 38.5±14.2 years; 100% males) were diagnosed to have opioid induced GI ulcers and/or ulcerated strictures. The mean duration of opioid consumption was 6.2±3.4 years. The mean duration of symptoms at presentation was 222.1±392.3 days. Thirteen patients (65%) had gastroduodenal involvement, 6 (30%) had a jejunoileal disease and 1 (5%) had an ileocecal stricture. Two patients (10%) presented with upper GI bleeding, 11 (55%) had features of gastric outlet obstruction and 7 (35%) presented with small bowel obstruction. Abdominal pain and iron deficiency anemia were the most common presentations. Only 1 patient (5%) responded to proton pump inhibitors, 3 (15%) had a lasting response to endoscopic balloon dilatation, while all other (80%) required surgical intervention. Conclusions: Opioid abuse gastroenteropathy presents as ulcers and ulcerated strictures which respond poorly to medical management and endoscopic balloon dilatation. A majority of these cases need surgical intervention. (Intest Res 2020;18:238-244)
Liton Balo,Himani Gupta,Shishir Kumar Singh,Varun Kumar Singh,Shalu Kataria,Rajendra Kumar Singh 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.65 No.-
Flexible gel polymer electrolytes based on polymer polyethylene oxide, salt lithium bis(fluorosulfonyl)imide and ionic liquid 1-ethyl-3-methylimidazolium bis(fluorosulfonyl)imide are synthesized. Prepared samples show high thermal stability, high ionic conductivity at room temperature and an electrochemical stability window of ∼3.51 V vs. Li/Li+. Lithium deposition-striping voltage profiles show the formation of a stable solid electrolyte interface. A Li/GPE/LiFePO4 cell was assembled by low cost thermal lamination technique. This cell can deliver 143 mAh g−1 capacity at room temperature at C/20 rate with good discharge efficiency. Use of micro grid mesh type Al current collector in cathode exhibits significant improvement in capacity retention.
( Arshdeep Singh ),( Yogesh Kumar Gupta ),( Ashvin Singh Dhaliwal ),( Bhavjeet Kaur Kahlon ),( Vasu Bansal ),( Ramit Mahajan ),( Varun Mehta ),( Dharmatma Singh ),( Ramandeep Kaur ),( Namita Bansal ) 대한장연구학회 2023 Intestinal Research Vol.21 No.3
Background/Aims: The inflammatory bowel disease (IBD)-disk is a validated, visual, 10-item, self-administered questionnaire used to evaluate IBD-related disability. The present study aimed to evaluate IBD-disk in assessment of IBD daily life burden and its relation with disease activity. Methods: A cross-sectional study was conducted between June 2021 and December 2021. Patients with IBD were asked to complete the IBD-disk and a visual analogue scale of IBD daily-life burden (scored from 0-10, score >5 indicative of high burden). The internal consistency of IBD-disk, correlation with IBD daily life burden and disease activity (assessed by partial Mayo score and Harvey Bradshaw Index in patients with ulcerative colitis [UC] and Crohn’s disease [CD], respectively) and diagnostic performance of IBD-disk to detect high burden were analyzed. Results: Out of the 546 patients (mean age 40.33±13.74 years, 282 [51.6%] males) who completed the IBD-disk, 464 (84.98%) had UC and the remaining (n=82, 15.02%) had CD. A total of 311 patients (291 UC and 20 CD; 56.95%) had active disease. The mean IBD-disk total score and IBD daily life burden were 18.39±15.23 and 2.45±2.02, respectively. The IBD-disk total score correlated strongly with the IBD daily life burden (ρ=0.94, P< 0.001), moderately with partial Mayo score (ρ=0.50) and weakly with Harvey Bradshaw Index (ρ=0.34). The IBD-disk total score >30 predicted high IBD daily-life burden. Conclusions: The IBD-disk accurately predicts the daily life burden and parallels disease activity in patients with IBD and can be applied in clinical practice. (Intest Res 2023;21:375-384)
ROOM TEMPERATURE DEPOSITION OF SINGLE-WALLED CARBON NANOTUBE THIN FILMS
SEUNG YOL JEONG,BHARVIN PAREKH,VARUN GUPTA,GIOVANNI FANCHINI,MANISH CHHOWALLA 성균관대학교(자연과학캠퍼스) 성균나노과학기술원 2010 NANO Vol.5 No.5
A simple method for direct deposition of single-walled carbon nanotube (SWNT) networks on flexible substrates at room temperature is reported. Deposition of thin films was carried out using a two-zone tube furnace where the nucleation and growth of SWNTs occur in vapor phase in the hot zone and condense onto substrates in the cold zone. Raman spectroscopy and scanning electron microscopy reveal individual, uniformly distributed SWNTs over large areas (several cm2). The coverage density of the SWNTs on flexible substrates can be controlled by the location of the substrates within the cold zone. The opto-electronic properties of the thin films indicated that they can be transparent and conducting with sheet resistances ranging from 4 to 21 kΩ/sq at corresponding transparencies of 51 to 87%, respectively.
Incidental benefits after fecal microbiota transplant for ulcerative colitis
( Ramit Mahajan ),( Vandana Midha ),( Arshdeep Singh ),( Varun Mehta ),( Yogesh Gupta ),( Kirandeep Kaur ),( Ritu Sudhakar ),( Anmol Singh Pannu ),( Dharmatma Singh ),( Ajit Sood ) 대한장연구학회 2020 Intestinal Research Vol.18 No.3
Gut dysbiosis can result in several diseases, including infections (Clostridium difficile infection and infectious gastroenteritis), autoimmune diseases (inflammatory bowel disease, diabetes, and allergic disorders), behavioral disorders and other conditions like metabolic syndrome and functional gastrointestinal disorders. Amongst various therapies targeting gut microbiome, fecal microbiota transplantation (FMT) is becoming a focus in the public media and peer reviewed literature. We have been using FMT for induction of remission in patients with moderate to severe active ulcerative colitis (UC) and also for subsequent maintenance of remission. Four cases reported incidental benefits while being treated with FMT for UC. These included weight loss (n = 1), improvement in hair loss (n = 1), amelioration of axial arthritis (n = 1) and improvement in allergic rhinitis (n = 1), thereby suggesting potential clinical applications of FMT in treating extraintestinal diseases associated with gut dysbiosis. (Intest Res 2020;18:337-340)