http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
An Enhanced Dynamic Multilayer Routing for Networks with Protection Requirements
Urra, Anna,Calle, Eusebi,Marzo, Jose L.,Vila, Pere The Korea Institute of Information and Commucation 2007 Journal of communications and networks Vol.9 No.4
This paper presents a new enhanced dynamic and multilayer protection(DMP) routing scheme that considers cooperation between packet and wavelength switching domain in order to minimize the resource consumption. The paper describes the architecture of the multilayer network scenario and compares the proposed algorithm with other routing mechanisms applying protection at the IP/multi-protocol label switching(MPLS) layer or at the optical layer. Simulation results show that DMP reduces the number of optical-electrical-optical(o-e-o) operations and makes an efficient use of the network resources compared to non-multilayer proposals.
L. Garcés,C. Vásquez,E. Contreras,J. Urra,M.C. Diez,L. Guerrero,C. Palma 한국생물공학회 2012 Biotechnology and Bioprocess Engineering Vol.17 No.5
Recycling industrial wastes is one of the major goals of bioengineering research. Agricultural wastes are often rich in natural sources of organic and inorganic compounds. The present study investigates the use of banana peel waste as a non-conventional alternative to nitrogen-enriched glucose media for a white rot fungus (WRF), Inonotus sp. SP2, recently isolated in southern Chile. WRF are known to produce biodegrading enzymes,such as peroxidases, that can have industrial and biotechnological applications. To that end, the metabolic characteristics and catalytic properties of peroxidases produced by Inonotus sp. SP2 were compared between glucose and banana peel-based growth mediums. The results establish that this strain of WRF produces high concentrations of a Mn+2-dependent peroxidase, with greater enzymatic activity in extracellular fluid and crude enzyme extracted from fungus grown in banana peel and glucose media,respectively. H2O2 has an inhibiting effect that is greater for enzymes produced in glucose media, and greater biomass can be obtained in banana-peel based media. This demonstrates that banana peel is a suitable and more cost-effective alternative to conventional glucose-based media for the production of biodegradative enzymes, such as peroxidase. Unlike other strains of WRF, the metabolic characteristics of Inonotus sp. SP2 demonstrate that it enters secondary metabolism with the production oxidative enzymes after both carbon and nitrogen sources are depleted. This suggests that with further investigation, this strain of WRF may be useful in industrial applications that require the biodegradation of nitrogen and carbon-based wastes and recalcitrant compounds.
Larissa Akemi Kido,Isabela Maria Urra Rossetto,Andressa Mara Baseggio,Gabriela Bortolanza Chiarotto,Letícia Ferreira Alves,Felipe Rabelo Santos,Celina de Almeida Lamas,Mário Roberto Maróstica Jr,Valér 대한암예방학회 2022 Journal of cancer prevention Vol.27 No.3
Jaboticaba is a Brazilian berry, which is rich in fibers and bioactive compounds and shows high antioxidant and antiproliferative activities. Prostate cancer (PCa) is the second most common type of cancer among men and its progression is influenced by androgens and inflammation. Previous studies reported the ability of the jaboticaba to modulate pathways involved in prostate diseases. The main objective of this study was to provide significant data about molecular targets of the jaboticaba peel extract (JPE) and its mechanisms of action in PCa cell lines with different androgenic status (LNCaP and PC-3). The results showed that JPE was able to decrease cell viability in both cell lines. LNCaP showed more sensitivity to JPE exposure, indicating the efficacy of the JPE treatment in terms of androgen responsiveness. JPE showed a distinct hormone dependent effect on the NF-κB signaling, with reduced NF-κB levels for LNCaP and increased NF-κB levels in PC-3 cells. Mechanisms related to cell death by apoptosis were stimulated after the JPE treatment, modulating B-cell lymphoma 2 and BAX for LNCaP and PC-3. Particularly for PC-3, the JPE treatment resulted in cytokine-cytokine receptor interaction activation mostly by up regulating pro-inflammatory, pro-angiogenic, immunostimulatory and immunosuppressive genes. Also, a set of genes related to angiogenesis and metastasis were down-regulated by JPE. In conclusion, JPE exerted an antitumor effect on PCa for both cell lines which can be enhanced if androgenic reliance is considered.