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Empty nose syndrome treated by autologous auricular cartilage turbinate augmentation: a case report
Wu Tzu-I,Hao Chung-Yu,Chiu Yu-Hsun 대한미용의학회 2021 대한미용의학회지 Vol.5 No.2
Empty nose syndrome (ENS), once viewed as a psychological issue, is now a recognized complication of turbinate surgery. It is most frequently associated with total turbinate excision. Its symptoms include chronic dryness of the nose and pharynx, paradoxical obstruction of the nose, feeling of suffocation, lack of airflow sensation, and even neuropathic pain. It may cause severe stress upon the patient resulting in mood instability issues. Surgical treatment to augment turbinate volume has been reported to be an effective treatment method. We would like to report a case of ENS treated by autologous auricular cartilage turbinate augmentation.
Hsin-I LEE,Tzu-Yu LIN,Silin WU,Sheng-Hsiung CHIU 한국유통과학회 2018 KODISA ICBE (International Conference on Business Vol.2018 No.-
China is the largest international students exporting country in the world. Base on the economic globalization and trade liberalization, the international talents cultivation, and how to assure their quality of higher education are important to China. This paper aims at finding out the dimensions influencing the quality of studying abroad. To obtain the weight and influential degree of the dimensions, we identify four criteria and sub-criteria mainly from the literatures related to learning quality in higher education and cross-cultural communication. To handle the inter-relations among the identified criteria and sub-criteria, we proposed a multi-criteria decision-making (MCDM) approach based on Decision Making Trial and Evaluation Laboratory based Analytic Network Process (DANP). This paper established how the obtained results will help the teachers in higher education system and Ministry of Education to optimize their improvement plans.
Chyong-Huey Lai,Elizabeth Vallikad,Hao Lin,Lan-Yan Yang,Shih-Ming Jung,Hsueh-Erh Liu,Yu-Che Ou,Hung-Hsueh Chou,Cheng-Tao Lin,Huei-Jean Huang,Kuan-Gen Huang,Jiantai Qiu,Yao-Ching Hung,Tzu-I Wu,Wei-Yang 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.1
Objectives: An Asian Gynecologic Oncology Group phase III randomized trial was conducted to determine whether maintenance chemotherapy could improve progression-free survival (PFS) in stages III/IV ovarian cancer. Methods: Between 2007 and 2014, 45 newly-diagnosed ovarian cancer patients were enrolled after complete remission and randomized (1:1) to arm A (4-weekly carboplatin area under the curve 4 and pegylated liposomal doxorubicin [PLD] 30 mg/m2, n=24) for 6 cycles or arm B (observation, n=21). The primary end-point was PFS. A post hoc translational study was conducted to deep sequence BRCA/homologous recombination deficiency (HRD) genes, because BRCA/HRD mutations (BRCA/HRDm) are known to be associated with better prognosis. Results: Enrollment was slow, accrual was closed when 7+ years had passed. With a median follow-up of 88.9 months, the median PFS was significantly better in arm A (55.5 months) than arm B (9.2 months) (hazard ratio [HR]=0.40; 95% confidence interval [CI]=0.19–0.87; p=0.020), yet the median overall survival was not significantly different in arm A (not reached) than arm B (95.1 months) (p=0.148). Overall grade 3/4 adverse events were more frequent in arm A than arm B (60.9% vs 0.0%) (p<0.001). Quality of life was generally not significantly different. Distribution of BRCA1/2m or BRCA/HRDm was not significantly biased between the two arms. Wild-type BRCA/non-HRD subgroup seemed to fare better with maintenance therapy (HR=0.35; 95% CI=0.11–1.18; p=0.091). Conclusions: Despite limitations in small sample size, it suggests that maintenance carboplatin-PLD chemotherapy could improve PFS in advanced ovarian cancer.