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      • KCI등재

        Revascularization of Concurrent Renal and Cerebral Artery Stenosis in a 14-Year-Old Girl with Takayasu Arteritis and Moyamoya Syndrome

        Meng-Luen Lee,Ming-Yuh Chang,Tung-Ming Chang,Rei-Cheng Yang,Ming-Che Chang,Albert D. Yang 대한의학회 2018 Journal of Korean medical science Vol.33 No.10

        Concurrent involvement of bilateral renal and cerebral arteries, usually incurred as stenosis is rare in childhood-onset Takayasu arteritis (c-TA). We report the case of a 14-year-old girl, with c-TA, presenting with transient ischemic attack after endovascular revascularization for renal artery stenosis and cerebrovascular stroke after surgical revascularization for cerebral artery stenosis associated with childhood-onset moyamoya syndrome. We deem th decrease of blood pressure by endovascular revascularization and improvement of cerebral perfusion by surgical revascularization may have jeopardized the cerebral deep watershed zone to cerebral ischemia followed by cerebral hyperperfusion syndrome and caused transient ischemic attack and cerebrovascular stroke in our patient. Revascularization could be a double-edge sword for c-TA patients presenting with concomitant renal artery stenosis and cerebral artery stenosis, and should be performed with caution. Quantitative analysis of cerebral blood flow by brain magnetic resonance imaging and angiography should be performed within 48 hours after surgical revascularization in c-TA.

      • KCI등재

        Dark current suppression of amorphous selenium based photosensors by the ZnO hole blocking layer

        Tung-Yuan Yu,Fu-Ming Pan,Cheng-Yi Chang,Tien Hu,Jenn-Fang Chen,Jia-Feng Wang,Jia-Feng Wang,Cheng-Lu Lin,Te-Ming Chen 한국물리학회 2014 Current Applied Physics Vol.14 No.5

        To study the influence of defects in the hole blocking layer (HBL) on the dark current of amorphous selenium (a-Se) based photosensors, we prepared ZnO thin films by reactive sputter deposition (RSD) for the use as the HBL of the photosensors. The ZnO HBL layers prepared with different oxygen flow rates were characterized by X-ray photoelectron spectroscopy, Raman scattering analysis and photoluminescence, indicating that the density of oxygen vacancies in the ZnO thin films is significantly affected by the oxygen flow rate. The deep level transient spectroscopy measurement reveals two hole trap levels present in the RSD deposited ZnO thin films; one is at 0.94 eV and the other at 0.24 eV above the valence band edge. The electrical performance of the a-Se photosensor is largely influenced by the amount of oxygen vacancies in the ZnO thin film. The a-Se photosensor with the ZnO HBL of the most oxygen vacancies has the lowest dark current and demonstrates the highest breakdown field.

      • SCIESCOPUSKCI등재

        Stability Analysis of Perforated Plate Type Single Stage Suspension Fluidized Bed Without Downcomer

        Lu, Wei Ming,Ju, Sheau Pyng,Tung, Kuo Lun,Lu, Yu Chang 한국화학공학회 1999 Korean Journal of Chemical Engineering Vol.16 No.6

        The stability of operation of a perforated plate type suspension bed without downcomer was analyzed experimentally and numerically. The effects of the feed rate, the gas flowrate and the opening ratio and hole diameter of the perforated plates on the operating stability of the fluidized bed were examined. A full three-dimensional discrete particle simulation method proposed by Tsuji [1993] was performed to study the formation of a stable suspension fluidized bed. The course and behavior of particles that formed a dense and stable fluidized bed are discussed. Both the experimental and simulation results of this study show that the process of forming a suspension bed can be categorized into (i) an induced stage, (ii) a growing stage, and (iii) a stable stage. The velocity of gas through the orifice directly controls the formation of the bed while the solid flow rate over a considerable range maintains a balanced hold-up in the suspension bed system without downcomers. The existence of a multiplicity of steady states corresponding to different gas flow rates, for the same feed rate and perforated plate type, was observed. Results show that the design of the plate, the particle feed rate and the gas velocity distribution through the hole affect the stability of the fluidized bed. The simulated results agree qualitatively well with experimental observations.

      • KCI등재

        Epidemiological trend in inflammatory bowel disease in Taiwan from 2001 to 2015: a nationwide population-based study

        Hsu-Heng Yen,Meng-Tzu Weng,Chien-Chih Tung,Yu-Ting Wang,Yuan Ting Chang,Chin-Hao Chang,Ming-Jium Shieh,Jau-Min Wong,Shu-Chen Wei 대한장연구학회 2019 Intestinal Research Vol.17 No.1

        Background/Aims: Incidences of inflammatory bowel disease (IBD), ulcerative colitis (UC), and Crohn’s disease (CD), havebeen increasing in Asia. In this study, we report the relevant clinical characteristics and determined the epidemiological trend ofIBD in Taiwan from 2001 to 2015. Methods: A retrospective study was conducted to analyze data recorded from January 2001through December 2015 in the registered database compiled by the National Health Insurance and provided by the Ministry ofHealth and Welfare, Taiwan. Results: A total of 3,806 patients with catastrophic IBD illness were registered from 2001 to 2015 inTaiwan (CD, 919; UC, 2,887). The crude incidence of CD increased from 0.17/100,000 in 2001 to 0.47/100,000 in 2015, whereasthat of UC increased from 0.54/100,000 in 2001 to 0.95/100,000 in 2015. The prevalence of CD increased from 0.6/100,000 in2001 to 3.9/100,000 in 2015, whereas that of UC increased from 2.1/100,000 in 2001 to 12.8/100,000 in 2015. The male-to-femaleratio in the study sample was 2.19 for CD and 1.62 for UC. The median age of those registered with CD was lower than that ofthose registered for UC: 38.86 and 44.86 years, respectively. A significantly greater increase in CD incidence rate was identifiedamong 20 to 39-year-old compared with other age groups. Conclusions: Using Taiwan’s nationwide insurance database, we determinedthat the number of patients with CD increased more rapidly during the study period than the number of patients withUC, especially among age 20 to 39-year-old, resulting in a decreased UC-to-CD ratio. (Intest Res 2019;17:54-62)

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