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Effect of Compression Overload on Fatigue Strength Improved by ICR Treatment
Toshiyuki Ishikawa,Masaru Shimizu,Hajime Tomo,Hirotaka Kawano,Kentaro Yamada 한국강구조학회 2013 International Journal of Steel Structures Vol.13 No.1
ICR (Impact Crack-closure Retrofit) treatment was developed for extending fatigue life of cracked steel structures by closing the fatigue crack opening. By applying the ICR treatment to as-welded condition, compressive stress remains at weld toe. Therefore, ICR treatment can be used for the improvement of fatigue strength of welded joint at the same level of the other fatigue strength improved techniques. If a compression overload is subjected after ICR treatment, however, the residual compressive stress at weld toe will shift the tensile stress region. Accordingly, improved fatigue strength of welded joints by ICR treatment will be reduced after the compression overloaded. In order to investigate the effect of the compression overload on fatigue strength improved by ICR treatment, fatigue tests of out-of-plane gusset specimens were carried out. As the results,fatigue strength improved by ICR treatment was hardly reduced under the compression overload condition of nominal stress of −190 MPa.
Suguru Odajima,Toshiyuki Seki,Sayako Kato,Keisuke Tomita,Yuichi Shoburu,Eitaro Suzuki,Masataka Takenaka,Motoaki Saito,Hirokuni Takano,Kyosuke Yamada,Aikou Okamoto 대한부인종양학회 2022 Journal of Gynecologic Oncology Vol.33 No.5
Objective: Direct oral anticoagulants (DOACs) are increasingly being used for the treatment of cancer-associated venous thromboembolism (CAT). However, there is limited evidence of the efficacy of DOACs for the treatment of gynecological CAT. Thus, this study aimed to investigate the efficacy and safety of edoxaban for the treatment of gynecological CAT using Japanese real-world data. Methods: We reviewed the medical records of patients with 371 gynecological cancer who received edoxaban or vitamin K antagonist (VKA) between January 2011 and December 2018. Results: Altogether, 211 and 160 patients were treated with edoxaban and VKA, respectively. Fourteen patients (6.8%) in the edoxaban group and 22 (13.8%) in the VKA group showed recurrence of venous thromboembolism (VTE). Cumulative VTE recurrence was not significantly different between the 2 groups (p=0.340). Adverse events occurred in 15 (7.1%) and 11 (6.9%) patients in the edoxaban and VKA groups, respectively (p=0.697). Subgroup analysis of the edoxaban and VKA groups according to different tumor types, including ovarian, endometrial, and cervical cancer, showed equivalent outcomes in terms of VTE recurrence and adverse events. Patients without pulmonary embolism (PE) were mostly omitted from initial unfractionated heparin (UFH) therapy prior to administration of edoxaban. However, this did not increase the recurrence of VTE. Conclusion: This study confirmed that edoxaban is effective and safe for the treatment of gynecological CAT. This finding was consistent for different types of gynecological cancer. Additionally, initial UFH therapy prior to the administration of edoxaban may be unnecessary for patients without PE.
Fatigue Strength of Fillet Welded Joint subjected to Plate Bending
Biehn Baik,Kentaro Yamada,Toshiyuki Ishikawa 한국강구조학회 2008 International Journal of Steel Structures Vol.8 No.3
Fatigue tests have been carried out on three types of non load-carrying fillet welded joint subjected plate bending, such as single-side fillet welded joint, T-shaped fillet welded joint and cruciform fillet welded joint. Fatigue failure of each welded joint has been demonstrated. The test results show that fatigue crack forms flat semi-ellipse during crack propagation and propagates to about 80% of plate thickness before failure. The fatigue strength and life recorded under bending test have been examined and compared with the previous results obtained by tension test. The fatigue strength of the fillet welded joint under bending is higher than that of the welded joint under tension. Fatigue tests have been carried out on three types of non load-carrying fillet welded joint subjected plate bending, such as single-side fillet welded joint, T-shaped fillet welded joint and cruciform fillet welded joint. Fatigue failure of each welded joint has been demonstrated. The test results show that fatigue crack forms flat semi-ellipse during crack propagation and propagates to about 80% of plate thickness before failure. The fatigue strength and life recorded under bending test have been examined and compared with the previous results obtained by tension test. The fatigue strength of the fillet welded joint under bending is higher than that of the welded joint under tension.
Fault Analysis of Interconnect Opens in 90nm CMOS ICs with Device Simulator
Masaki Hashizume,Yuichi Yamada,Hiroyuki Yotsuyanagi,Toshiyuki Tsutsumi,Koji Yamazaki,Yoshinobu Higami,Hiroshi Takahashi,Yuzo Takamatsu 대한전자공학회 2008 ITC-CSCC :International Technical Conference on Ci Vol.2008 No.7
In this paper, faulty effects of interconnect opens in logic ICs fabricated with a 90㎚ CMOS process are analyzed by device simulation. In the analysis, it is examined whether a logical error can be caused at an opened input signal line by logic signals of the neighboring signal lines. The simulation results suggest us that a logical error may occur at an interconnect surrounding by 8 interconnects if the interconnects are longer than 5㎛ and the width of an open defect is greater than 2.0㎚.