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New Prognostic Scoring System for Incurable Stage IV Colorectal Cancer
Kishiki, Tomokazu,Masaki, Tadahiko,Mastuoka, Hiroyoshi,Abe, Nobustugu,Mori, Toshiyuki,Sugiyama, Masanori Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.2
Background: Components of the systemic inflammatory response, combined to form inflammation-based prognostic scores (mGPS, NLR, PLR, PI, PNI) have been associated with overall survival. The aim of the present study was to compare various prognostic factors including many previously established parameters and such systemic inflammation-based prognostic scores in a series of incurable stage IV colorectal cancer (CRC) patients. Materials and Methods: Patients (n=167) with stage IV CRC undergoing surgical procedures between 2005 and 2013 were enrolled. Preoperatively (7-30 days before surgery), routine laboratory examinations were performed on the same day. We calculated scores using these data and analyzed the association with cancer specific survival (CSS) statistically. Results: Univariate analysis revealed significant associations between CSS and WBC, albumin, CRP, CEA values, mGPS, PNI, and PI values among preoperative factors. On multivariate analysis, high mGPS and high CEA independently predicted shorter CSS (p=0.001 and p=0.018). A new scoring system was constructed using mGPS and CEA. When patients were separated into three categorized using this system, the new score accurately predicted CSS (p < 0.001). Conclusions: The present study indicates that a new scoring system, consisting of mGPS and CEA, is a simple and useful tool in predicting the survival of patients with incurable stage IV CRC, and should be included in the routine assessment of these patients for decision making of appropriate treatment.
Study of Winding Method to Reduce Stray Loss and Stator Core Vibration of Synchronous Machine
Hiramatsu, Daisuke,Sutrisna, Kadek Fendy,Ishizuka, Hiroaki,Okubo, Masashi,Tsujikawa, Kazuma,Ueda, Takashi,Hachiya, Hideyuki,Mori, Junji,Aso, Toshiyuki,Otaka, Toru Journal of International Conference on Electrical 2013 Journal of international Conference on Electrical Vol.2 No.3
The fractional slot windings are widely used in rotating machine in order to increase the flexibility of design and improve the voltage waveform. However, the MMF wave of fractional-slot windings are found to contain unique harmonic component, which are designated as even order space flux harmonics, fractional number flux harmonics, or both. They may cause stray loss and stator core vibration. This paper proposes new winding methods "novel interspersed windings" and "expanded group windings" to reduce these harmonics. The advantages of two proposed windings are verified by using numerical analysis and measurement test of winding model.
Hatanaka, Takaaki,Ohzono, Shinji,Park, Mirae,Sakamoto, Kotaro,Tsukamoto, Shogo,Sugita, Ryohei,Ishitobi, Hiroyuki,Mori, Toshiyuki,Ito, Osamu,Sorajo, Koichi,Sugimura, Kazuhisa,Ham, Sihyun,Ito, Yuji American Society for Biochemistry and Molecular Bi 2012 The Journal of biological chemistry Vol.287 No.51