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Ariane Leite Rozza,Thiago de Mello Moraes,Hélio Kushima,Domingos Sávio Nunes,Clélia Akiko Hiruma-Lima,Cla´udia Helena Pellizzon 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.9
This study aimed to evaluate the gastroprotective mechanism of action of the essential oil of Croton cajucara Benth. (Euphorbiaceae) stem bark in ethanol-induced gastric ulcers and its in vitro anti–Helicobacter pylori activity. The involvement of heat-shock protein-70, vasoactive intestinal peptide, glutathione, nitric oxide, and nonprotein sulfhydryl compounds in the gastroprotective effect was determined in male Wistar rats. The minimum inhibitory concentration against H. pylori was determined in vitro. The results were analyzed by analysis of variance followed by the Dunnett test, and a P value less than 0.05 was considered to represent a statistically significant difference. C. cajucara decreased ethanol-induced ulcer area in 100% of ulcers and decreased the histologic lesions. In the C. cajucara group, the area marked by heat-shock protein-70 was significantly higher than the area in the control group; this finding was not seen for vasoactive intestinal peptide. C. cajucara could not maintain glutathione levels close to those in the sham group. The gastric ulcer area of rats treated with the sulfhydryl compound blocker was decreased, but the ulcer area of rats treated with nitric oxide synthase inhibitor showed no alteration. The minimum inhibitory concentration obtained for C. cajucara was 125 μg/mL. These findings suggest that sulfhydryl compounds and heat-shock protein-70, but not nitric oxide, glutathione, or vasoactive intestinal peptide, are involved in the C. cajucara gastroprotective effect against ethanol-induced gastric ulcers.
Gustavo Batista de Castro Souza,Flávio Henrique Teles Vieira,Cláudio Ribeiro Lima,Getúlio Antero de Deus Júnior,Marcelo Stehling de Castro,Sérgio Granato de Araujo,Thiago Lara Vasques 한국전자통신연구원 2016 ETRI Journal Vol.38 No.1
Smart metering systems have become widespread around the world. RF mesh communication systems have contributed to the creation of smarter and more reliable power systems. This paper presents an algorithm for positioning GPRS concentrators to attain delay constraints for a ZigBee-based mesh network. The proposed algorithm determines the number and placement of concentrators using integer linear programming and a queueing model for the given mesh network. The solutions given by the proposed algorithm are validated by verifying the communication network performance through simulations.
Adilson V. Rodrigues,Thiago S. Lima,Talita A. Vida,Crystopher Brito,Amauri Garcia,Noé Cheung 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.5
Al–Cu–Ni alloys are of scientifi c and technological interest due to high strength/high temperature applications, based on thereinforcement originated from the interaction between the Al-rich phase and intermetallic composites. The nature, morphology,size, volume fraction and dispersion of IMCs particles throughout the Al-rich matrix are important factors determiningthe resulting mechanical and chemical properties. The present work aims to evaluate the effect of the addition of 1wt%Ni intoAl–5wt%Cu and Al–15wt%Cu alloys on the solidification rate, macrosegregation, microstructure features and the interrelationsof such characteristics on tensile and corrosion properties. A directional solidification technique is used permitting awide range of microstructural scales to be examined. Experimental growth laws relating the primary and secondary dendriticspacings to growth rate and solidification cooling rate are proposed, and Hall–Petch type equations are derived relating theultimate tensile strength and elongation to the primary dendritic spacing. Considering a compromise between ultimate tensilestrength and corrosion resistance of the examined alloys samples from both alloys castings it is shown that the sampleshaving more refined microstructures are associated with the highest values of such properties.
Talita A. Vida,Crystopher Brito,Thiago S. Lima,José E. Spinelli,Noé Cheung,Amauri Garcia 한국물리학회 2019 Current Applied Physics Vol.19 No.4
Zn-Mg alloys are considered to have potential application in bone implants, since both metals are biocompatible and have biodegradable characteristics. Adding Mg to Zn can boost mechanical and corrosion resistances. However, the literature is very limited on quantifying the interrelation of solidification parameters, microstructural features and mechanical/corrosion properties of Zn-Mg alloys. The present study examines the interrelations of alloy Mg content, macrosegregation effects, morphology and scale of the matrix and eutectic phases, nature of intermetallics and tensile and corrosion properties of near-eutectic Zn-Mg alloys. The alloys samples are obtained by unsteady-state directional solidification resulting in a wide range of solidification thermal parameters and microstructures. We examine microstructural features of both dendritic and complex regular eutectic phases. It is shown that the eutectic exhibits a bimodal pattern with neighboring areas of coarse and fine lamellae. Experimental growth laws relating the primary, secondary and eutectic spacings to the solidification cooling rate and growth rate are proposed. Hall-Petch type equations are derived expressing tensile strength and elongation to dendritic and eutectic spacings. Electrochemical parameters determined by polarization curves during corrosion tests and SEM analyses of corroded areas have shown that the alloy having an essentially eutectic microstructure is associated with better corrosion resistance.