Co-utilization of Maltose and Sodium Acetate via Engineered Corynebacterium glutamicum for Improved Itaconic Acid Production

Taghreed Elkasaby,Dao Duy Hanh,Hideo Kawaguchi,Masakazu Toyoshima,Akihiko Kondo,Chiaki Ogino 한국생물공학회 2023 Biotechnology and Bioprocess Engineering Vol.28 No.5

For growth and energy, Corynebacterium glutamicum has the ability to assimilate numerous carbon sources in the form of either single or combined substrates. During the growth of C. glutamicum on substrate mixtures, it has shown the ability to co-metabolize the majority of these carbon sources and displays monophasic growth, unlike other microorganisms such as Escherichia coli and Bacillus subtilis, which exhibit either diauxic or biphasic growth. Here, a recombinant strain of C. glutamicum ATCC 13032 was selected for the use in the production of itaconic acid (IA), which is a promising biochemical building block that could be an alternative material for polymer synthesis. For this purpose, an engineered C. glutamicum ATCC 13032 pCH-cadAopt was constructed by introducing the plasmid pCH-cadAopt, which expressed a cis-aconitate dehydrogenase gene (cadA) that originated from Aspergillus terreus. The production of IA was evaluated using a combined mixture of maltose and sodium acetate. The monophasic growth of C. glutamicum in the presence of maltose and sodium acetate was observed and showed final IA titer of 12.63 g/L, and a molar yield of 0.38 mol/mol after 240 h of cultivation. The present study suggests the possibility of utilizing a mixture of carbon sources by C. glutamicum to improve IA production.

A Simple Proposal For Ain Makkah Almukkarmah An Application Using Augmented Reality Technology

Taghreed Alotaibi,Laila Alkabkabi,Rana Alzahrani,Eman Almalki,Ghosson Banjar,Kholod Alshareef,Olfat M. Mirza International Journal of Computer ScienceNetwork S 2023 International journal of computer science and netw Vol.23 No.12

Makkah Al-Mukarramah is the capital of Islamic world. It receives special attention from the Saudi government's rulers to transform it into a smart city for the benefit of millions of pilgrims. One of the 2030 vision objectives is to transform specific cities to smart ones with advanced technological facilitation, Makkah is one of these cities. The history of Makkah is not well known for some Muslims. As a result, we built the concepts of our application "Ain Makkah" to enable visitors of Makkah to know the history of Makkah by using technology. In particular "Ain Makkah" uses Augmented Reality to view the history of Al-Kaaba. A 3D model will overlay Al-Kaaba to show it in the last years. Our project will use Augmented Reality to build a 3D model to overlay Al-Kaaba. Future work will expand the number of historical landmarks of Makkah.

Healthcare Security based on Blockchain

Almalki, Taghreed,Alzahrani, Shahad,Alhakami, Wajdi International Journal of Computer ScienceNetwork S 2021 International journal of computer science and netw Vol.21 No.8

One of the most important inventions and developments in the digital world today is the healthcare system based on blockchain technology. Healthcare is an important field that requires the application of security mechanisms due to the sensitivity of patient data. The association of blockchain with healthcare contributed to achieving better security mechanisms than the traditional approach. The new approach operates in a decentralized system, which in turn, improves security in the healthcare environment. Consequently, blockchain technology has emerged as one of the most crucial solutions to security violations and challenges in the healthcare industry. This paper provides a comprehensive review of several experts' recent protection and detection approaches in this domain. It is also imperative to note that the paper focuses only on the recent techniques that have been published during 2017-2020. The sophisticated procedures have been investigated and discussed in terms of similarities and differences to highlight the significance of the protection needed to secure the healthcare environment.

A Review: Synthesis and characterization of metals complexes with paracetamol drug

Salam R AL-Ayash,Taghreed H AL-Noor 한국분석과학회 2022 분석과학 Vol.35 No.4

In this review, previous studies on the synthesis and characterization of the metal Complexes with paracetamol by elemental analysis, thermal analysis, (IR, NMR and UV-Vis (spectroscopy and conductivity. In reviewing these studies, the authors found that paracetamol can be coordinated through the pair of electrons on the hydroxyl O-atom, carbonyl O-atom, and N-atom of the amide group. If the paracetamol was a monodentate ligand, it will be coordinated by one of the following atoms O-hydroxyl, O-carbonyl or N-amide. But if the paracetamol was bidentate, it is coordinated by atoms (O-carbonyl and N-amide), (O-hydroxyl and N-amide) or (O-carbonyl and O-hydroxyl). The authors also found that free paracetamol and its complexes have antimicrobial activity.

Adversarial Machine Learning: A Survey on the Influence Axis

Alzahrani, Shahad,Almalki, Taghreed,Alsuwat, Hatim,Alsuwat, Emad International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.5

After the everyday use of systems and applications of artificial intelligence in our world. Consequently, machine learning technologies have become characterized by exceptional capabilities and unique and distinguished performance in many areas. However, these applications and systems are vulnerable to adversaries who can be a reason to confer the wrong classification by introducing distorted samples. Precisely, it has been perceived that adversarial examples designed throughout the training and test phases can include industrious Ruin the performance of the machine learning. This paper provides a comprehensive review of the recent research on adversarial machine learning. It's also worth noting that the paper only examines recent techniques that were released between 2018 and 2021. The diverse systems models have been investigated and discussed regarding the type of attacks, and some possible security suggestions for these attacks to highlight the risks of adversarial machine learning.

Metal complexes of alizarin and their biological and industrial applications: A literature review

Laith Jumaah Al-Gburi,Taghreed H. Al-Noor 한국분석과학회 2023 분석과학 Vol.36 No.2

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The use of a single-piece bone flap for cranial reshaping in anterior craniosynostosis patients: clinical experience and a description of a novel technique

Hatan Mortada,Ikhlas Altuawijri,Taghreed Alhumsi 대한악안면성형재건외과학회 2022 Maxillofacial Plastic Reconstructive Surgery Vol.44 No.-

Background: Craniosynostosis is known as premature closure of one or more of the cranial sutures. Anteriorcraniosynostosis involves anterior plagiocephaly and trigonocephaly. One of the issues in anterior craniosynostosisskull reshaping is maintaining an aesthetically pleasing forehead curve. Therefore, in this article, we demonstrate ournovel technique to use a single-piece bone flap for cranial reshaping of the anterior mold in patients diagnosedwith anterior craniosynostosis. A retrospective record review of patients who underwent single piece bone flapcranial reshaping for correction of unicoronal synostosis (UCS) and metopic synostosis (MS) at an Academic Institutein Riyadh, Saudi Arabia, between 2018 and 2020, was conducted. Results: Six non-syndromic consecutive patients were included. Three of the patients had MS. The mean age atsurgery was 11.16 months (range, 6?19 months). The average OR time was 315 min (range, 263?368 min). Theaverage intraoperative blood loss was 225 ml (range, 100?400 ml). All patients had achieved acceptable functionaland aesthetic results. Conclusion: Our novel technique is an innovative and efficient reconstructive technique to simultaneously addressMS and UCS and minimize intraoperative bleeding and surgery time. However, more studies with more cases arerequired.

Impact of COVID-19 on Entrepreneurship and Consumer Behaviour: A Case Study in Saudi Arabia

Adlah A,ALESSA,Taghreed M,ALOTAIBIE,Zaabi ELMOEZ,Haton E,ALHAMAD 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.5

COVID-19 presented the world with a severe loss of life and impact, which has no geographical bounds or expected time to when its effects will subside. It has affected countries across the globe, disrupting economic levels and businesses in every industry while also altering individuals’ everyday lives. The current research aims to examine the impact of coronavirus pandemic on entrepreneur’s business activities and their perceptions on the difference in consumer behavior during this time. The findings reveal the pandemic negatively impacted business productivity and profits, forcing many businesses to physically close permanently. Surprisingly, female entrepreneurs do not perceive a change in consumer behavior compared to pre-COVID-19 times. Interestingly, the results indicate there is a negative impact on employees’ efficiency to conduct work in which almost no research has conveyed such a finding. For this purpose, a survey was conducted with 445 responses from male and female entrepreneurs in the capital city of Riyadh, Saudi Arabia, using a simple random sample over the period of four months. Ultimately, this research will help entrepreneurs gain more knowledge and a deeper understanding of this new environment necessary to undertaking certain measures and adaptability in order to sustain their businesses during unprecedented times.

A career in academia? Determinants of academic career aspirations among PhD students in one research university in the US

김은영,Stefanie Benson,Taghreed A. Alhaddab 서울대학교 교육연구소 2018 Asia Pacific Education Review Vol.19 No.2

In the declining academic job market—with fewer tenured and tenure-track posts and an increased use of part-time faculty coupled with constant high attrition rates in doctoral education in the United States—the quality and value of graduate education have recently come under scrutiny. Most of the literature on graduate education focuses on doctoral training and socialization experiences, identifies factors that contribute to students’ degree completion, and illuminates what demographic characteristics may complicate the process of graduate education. While a growing body of research has documented the variations in graduate student socialization by department, academic discipline, and institutional and organizational contexts—and critiqued a monolithic treatment of doctoral education—few studies look at the relationship between doctoral training and career development. This study integrates doctoral socialization, role identity, and competence development into a conceptual model for examining factors that influence doctoral students’ intent to choose an academic career. Based on the data analysis of a sample of 316 doctoral students in a public, research-oriented U.S. university, we provide a discussion of key factors identified as important to doctoral students’ career aspirations and conclude with implications for practice and future research.

The Effectiveness of the Use of Distance-Evaluation Tools and Methods among Students with Learning-Difficulties from the Teachers' Point of View

Almaleki, Deyab A.,Khayat, Wejdan W.,Yally, Taghreed F.,Al-hajjaji, Aysha A. International Journal of Computer ScienceNetwork S 2021 International journal of computer science and netw Vol.21 No.5

This study aimed to identify the effectiveness of the use of distance-evaluation tools and methods among students with learning difficulties from the teachers' point of view, to achieve this goal. A scale was built, and the psychometric characteristics were validated. It consisted, in its final form, of 17 items distributed on four axes, in addition to three open questions. It was applied to a random sample of (149) teachers of students with learning difficulties in Makkah Region. The results showed that teachers' keenness to encourage students with learning difficulties, so that they would not feel frustrated with the distance learning process. It was also evident that teachers did not use achievement portfolios in the evaluation process. In connection with the appropriate evaluation methods, the majority indicated the use of work sheets and visual evaluation methods that rely on audio and visual skills, such as presenting videos, pictures, audio and games, and applying short objective tests. Among the proposals to improve evaluation methods and tools: Individual evaluation, attention to individual treatment, obligating personal attendance of students to school, splitting the required tasks, and not increasing the skills required to be mastered. As for the obstacles that teachers face: Lack of time, difficulty in communicating with students with distance learning difficulties and problems related to the Internet such as interruption, weakness, or lack of availability.