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      • 근이영양증(muscular dystrophy) 환자의 전신마취 하 치과치료 : 증례보고

        채종균(Jong Kyun Chae),송지수(Ji-Soo Song),신터전(Teo Jeon Shin),현홍근(Hong-Keun Hyun),김정욱(Jung-Wook Kim),장기택(Ki-Taeg Jang),이상훈(Sang-Hoon Lee),김영재(Young-Jae Kim) Asia association of Disability and Oral health 2019 International Journal of Disability and Oral Healt Vol.15 No.1

        본 증례는 다수의 치아우식증을 주소로 내원한 근이영양증 환자의 전신마취 하 치과치료에 대한 보고이다. 근이영양증 환자들은 진행성 근육 약화로 인해 구강위생 관리하기가 힘들고 치아우식이 호발할 수 있다. 따라서 정기적으로 치과를 내원하고 올바른 구강 위생 습관을 확립할 수 있도록 환자 및 보호자교육을 실시하여야 한다. 치과치료 시에는 흡인으로 인한 호흡기 합병증이 발생하지 않도록 액체의 흡입을 주의 깊게 하여야 한다. 비협조적이거나 매우 어린 근이영양증 환자에서는 전신마취가 필요할 수 있다. 전신마취 시에는 악성 고열증의 위험 때문에 휘발성 마취제를 피해야 한다. Muscular dystrophy (MD) is a heterogeneous group of inherited neuromuscular disorders, characterized by progressive muscle weakness. Severity of the disease ranges from mild to severe, and the disease is mostly caused by mutations in a number of genes. These genetic mutations cause lack of proteins which are essential for muscle cell stability. Muscle fibers are gradually replaced by fat and fibrous tissue. The muscles of the head and neck are affected in several types of MD that manifest as altered craniofacial morphology and dental malocclusion. A 3-year-10-month old, 15.0 kg boy with MD presented to Seoul National University Dental Hospital, Seoul, South Korea because of extensive carious teeth. A number of dental caries in primary dentition were identified during clinical oral examination. Due to dental anxiety and underlying systemic disease, general anesthesia was considered. General anesthesia was induced and maintained with intravenous anesthetics, propofol and remifentanil. Caries treatments - resin restoration, pulpectomy, zirconia crown restoration, stainless steel crown restoration - were performed. Under general anesthesia, successful dental procedure was done. Total intravenous anesthesia (TIVA) was performed instead of inhalation anesthesia in order to avoid risk of complications such as malignant hyperthermia and life-threatening rhabdomyolysis. With decreasing muscle function, plaque control becomes more difficult and leads to gingivitis. Especially, the open-mouth posture worsens gingivitis and can leads to malocclusions and problems in swallowing. Regular and periodic dental care is essential for maintaining oral health for patients with MD.

      • Cu-Sn 소결 마찰재에 C와 Cu 함량이 마찰특성에 미치는 영향

        함효균(Hyo Kyun HAM),최석의(Seok Eui CHOI),오용택(Yong Taeg OH),최희범(Hee Bum CHOI),김향래(Hang Rae KIM),최형기(Hyung Gi CHOI),이현규(Hyun Kyu LEE),신동찬(Dong Chan SHIN) 한국트라이볼로지학회 2009 한국트라이볼로지학회 학술대회 Vol.2009 No.11

        We have investigated the effects of graphite and cupper contents on the tribological properties of Cu-Sn sintered friction materials. The base materials used was Cu-Sn alloy. We varied graphite contents from 20 to 30 vol% with an interval of 5% and Cu contents of 25 and 35 vol%. All the specimens were sintered for 30 min at 750℃, nitrogen atmosphere by hot press method. Their friction and abrasive characteristics was evaluated by 1/5 Scale dynamometer. When the Cu content is decreased, we can get higher friction coefficient and less abrasion. The lowest abrasion was obtained at the condition of 30 vol% graphite. The highest friction coefficient was obtained in the specimen of 20 vol% graphite.

      • Physical Properties of Carbon Prepared from a Coconut Shell by Steam Activation and Chemical Activation and the Influence of Prepared and Activated Carbon on the Delivery of Mainstream Smoke

        Ko, Dong-Kyun,Shin, Chang-Ho,Jang, Hang-Hyun,Lee, Young-Taeg,Rhee, Moon-Soo The Korean Society of Tobacco Science 2008 한국연초학회지 Vol.30 No.1

        Several activated carbon in different specific surface area was prepared by steam and chemical activation of coconut shell. Products were characterized by BET ($N_2$) at 77K, and probed to be highly specific surface area of $1580m^2/g$ and pore volume that had increased with activating conditions. And also we have analyzed the adsorption efficiency of vapor phase components in cigarette mainstream smoke in order to evaluate the relationship between thesmoke components and the physicochemical properties of activated carbons. As a result of this study, the delivery of mainstream smoke was directly affected by the specific surface area and the pore size of activated carbon. The activated carbon prepared by steam activation exhibited better adsorption efficiency on the vapor phase components in mainstream smoke compared with activated carbon prepared by $ZnCl_2$, due to the higher micro-pore area of 66%. But the adsorption efficiency of semi-volatile matters such as phenolic components in a main stream smoke by the activated mesoporous carbon prepared by $ZnCl_2$ is more effective. From the these results, we can conclude that specific surface area by the micropore area increased the adsorption efficiency of activated carbon on vapour phase components, but semi-volatiles or particulate matter was affected by the ratio of mesopore area in total specific surface area.

      • 모야모야병(moyamoya disease) 환자의 전신마취 하 치과치료: 증례보고

        채종균(Jong Kyun Chae),송지수(Ji-Soo Song),신터전(Teo Jeon Shin),현홍근(Hong-Keun Hyun),김정욱(Jung-Wook Kim),장기택(Ki-Taeg Jang),이상훈(Sang-Hoon Lee),김영재(Young-Jae Kim) Asia association of Disability and Oral health 2019 International Journal of Disability and Oral Healt Vol.15 No.1

        본 증례는 다수의 치아우식증을 주소로 내원한 모야모야병 환자의 전신마취 하 치과치료에 대한 보고이다. 모야모야병은 치과치료 동안 상당히 주의를 필요로 하는 다양한 전신질환과 관련이 있다. 여러 과의 의사들과 협진이 필요하고, 치과 예방치료에 초점을 맞추면서 적절한 시기에 치료하는 것이 중요하다. 모야모야 환자에서 울음과 과호흡은 저칼륨혈증을 일으킬 수 있고, 대뇌 혈관 수축 효과를 일으킬 수 있다. 치과치료 시뇌졸중 발생을 예방하기 위해서 통증과 불안을 조절하는 것이 매우 중요하다. 비협조적이거나 매우 어린 모야모야병 환자에게 치과치료를 하기 위해서는 전신마취가 필요할 수 있다. Moyamoya disease (MMD) is a chronic, occlusive cerebrovascular disease of unknown etiology characterized by progressive stenosis at the terminal portion of the internal carotid artery and an abnormal vascular network at the base of the brain. The clinical presentations of MMD include transient ischemic attacks (TIA), ischemic stroke, hemorrhagic stroke, seizures, headache, and cognitive impairment. MMD is the most important cause of stroke or TIA in children in East Asian countries. A 5-year-3-month old boy with MMD experienced cerebral infarctions five times. Cerebrovascular anastomosis surgery was performed on him four years ago. He had dysphagia, developmental delay, hemiplegia, and strabismus. Besides, a number of dental caries in primary dentition were identified during clinical oral examination. Dental treatment under general anesthesia using sevoflurane was performed due to his lack of cooperation and underlying systemic disease. MMD is associated with various medical diseases requiring thoughtful consideration during dental treatment. Crying and hyperventilation in MMD patients may cause hypocapnia and have a cerebral vasoconstrictive effect. If dental treatment is required, control of pain and anxiety is very important. General anesthesia may be considered for dental treatment in uncooperative or very young patients with MMD.

      • Multi-Carbohydrase Addition Into a Corn-Soybean Meal Diet Containing Wheat and Wheat By Products to Improve Growth Performance and Nutrient Digestibility of Broiler Chickens

        Wickramasuriya, SamiruS.,Kim, Eunjoo,Shin, Taeg Kyun,Cho, Hyun Min,Kim, Beomgyu,Patterson, Rob,Yi, Young-Joo,Park, Sungkwon,Balasubramanian, Balamuralikrishnan,Heo, Jung Min Elsevier 2019 The Journal of applied poultry research Vol.28 No.2

        <P><B>SUMMARY</B></P> <P>Feed enzymes are used in poultry diets to enhance nutrient availability and thereby improve growth performances of the birds. The objective of the present study was to investigate the effect of dietary Multi-Carbohydrase (<B>MC</B>) supplementation on growth performance, blood metabolites, visceral organ weights, gut morphology, and nutrient digestibility in broiler chickens. A total of 168 one-day-old broiler chicks (47.5 ± 0.20 g) were randomly allocated into one of four dietary treatments in a 2 × 2 factorial arrangement with 6 replications per treatment. Dietary treatments were as follows: (1) positive control (<B>PC</B>; energy sufficient, 3,200 ME, kcal/kg); (2) negative control (<B>NC</B>; energy deficient, 3,100 ME, kcal/kg); (3) PC with MC (MC; Superzyme-CS™; 0.05%); (4) NC with MC. Greater ADG (<I>P</I> = 0.022) was observed with the birds fed MC for the entire period (1–35 d) compared to birds fed a diet without MC. Birds fed the NC diet supplemented with MC showed improved FCR (<I>P</I> = 0.037) compared to birds fed the NC diet during the starter period (1–21 d). MC supplementation increased dry matter (<I>P</I> = 0.029), crude protein (<I>P</I> = 0.015), and energy digestibility (<I>P</I> = 0.015) of the birds compared to those fed a diet without MC on day 21. Moreover, birds fed a diet with MC had increased (<I>P</I> = 0.037) dry matter digestibility on day 35 compared to its counterpart, regardless of dietary energy level. Therefore, our study indicated that MC improved growth performance along with nutrient digestibility in broiler chickens fed corn soybean-meal-based diets containing wheat and wheat by-products from hatch to 35 d of age, regardless of dietary energy level.</P>

      • KCI우수등재

        Estimating total lysine requirement for optimised egg production of broiler breeder hens during the early-laying period

        ( Eunjoo Kim ),( Samiru Sudharaka Wickramasuriya ),( Taeg Kyun Shin ),( Hyun Min Cho ),( Hyeun Bum Kim ),( Jung Min Heo ) 한국축산학회(구 한국동물자원과학회) 2020 한국축산학회지 Vol.62 No.4

        The production performance of broiler breeder hens in response to different levels of total lysine during the early laying period was investigated. A total of 126 Ross 308 parent stock hens were offered one of seven dietary treatments formulating elevated contents of total lysine ranging from 0.55% to 0.79% (0.04 scale; 133 g of feed) from 23 to 29 weeks of age. Each treatment had six replicates with three birds per pen. Body weight was recorded triweekly and eggs were collected and weighted at 9:00 am daily. One hen from each pen was euthanized to collect blood samples and visceral organs were harvested and weighed. Egg production, egg weight and egg mass were lower (p < 0.05) in hens offered a diet containing 0.55% total lysine compared to those fed the diet containing higher total lysine. Hens offered a diet containing 0.71%, 0.75%, and 0.79% total lysine had greater (p = 0.008) egg production rate compared to those offered a diet containing lysine less than 0.71%. The number of total eggs produced tended to be greater (p = 0.083) in hens offered a diet containing 0.71 and 0.75% total lysine compared to the other treatments. The number of settable egg production was higher (p < 0.001) in hens offered a diet contacting 0.79% total lysine compared to those fed the diet containing lower levels of total lysine. The relative weights of oviduct and ovary were lower (p < 0.05) in hens offered a diet containing 0.59% total lysine compared to the other treatments. No difference found in body weight, the number of total eggs, double- yolk eggs and abnormal shell eggs among the treatments. The urea nitrogen, estradiol-17 beta and progesterone in plasma were not affected by treatments. Based on linear- and quadratic- plateau models, total lysine requirements for egg production, settable egg production and egg mass at the early laying period were to be 0.73%, 0.77%, and 0.71%, respectively. Modern broiler breeder hens likely require higher total lysine than NRC recommendation in a diet for enhancing productivity during the early-laying period.

      • KCI등재

        Moderate dietary boron supplementation improved growth performance, crude protein digestibility and diarrhea index in weaner pigs regardless of the sanitary condition

        조현민,Macelline Shemil Priyan,Wickramasuriya Samiru Sudharaka,Shin Taeg Kyun,Kim Eunjoo,Son Hong Cheol,허정민 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.3

        Objective: The study was conducted to investigate the impact of boron supplementation on nutrient digestibility, inflammatory responses, blood metabolites and diarrhea index, and their relevance to growth performance in weaned pigs housed in good and poor sanitary environments for 14 days after weaning. Methods: A total of 108 male pigs (Duroc×[Yorkshire×Landrace]) weaned at 21 days of age were used in a randomized complete block design with 2×3 factorial arrangement. Pigs were assigned to three boron treatments (0, 5, and 10 mg/kg) under two environments (good and poor sanitary) to give six replicates per treatment (3 pigs per replicate). On 0, 7, and 14 days, one pig per replicate was euthanized to collect, ileum tissue samples, and rectal fecal samples. Results: Boron supplementation quadratically influenced (p<0.001) feed intake and weight gain in pigs housed in good sanitary conditions from 1 to 14 days post-weaning where pigs offered 5 mg/kg boron optimized weight gain and feed intake. There is a quadratic interaction (p = 0.019) on feed intake for 1 to 14 days post-weaning where 5 mg/kg boron increased feed intake in good sanitary conditions. Pigs housed in the poor sanitary environment decreased (p<0.001) villus height and crypt depth in ileum at days 7 and 14. On day 7 and 14, crude protein digestibility was quadratically influenced (p<0.05) by boron supplementation. Boron supplementation linearly increased (p<0.05) plasma calcium and cholesterol levels whilst linearly (p = 0.005) reducing plasma triglyceride concentrations. Diarrhea index was quadratically influenced (p<0.05) by boron supplementations regardless of sanitary conditions where 5 mg/kg boron inclusion achieved the lowest diarrhea index. Conclusion: Pigs offered 5 mg/kg of boron increased weight gain which may be deduced by improved dry matter, crude protein, and energy digestibility regardless of the sanitary conditions. Objective: The study was conducted to investigate the impact of boron supplementation on nutrient digestibility, inflammatory responses, blood metabolites and diarrhea index, and their relevance to growth performance in weaned pigs housed in good and poor sanitary environments for 14 days after weaning.Methods: A total of 108 male pigs (Duroc×[Yorkshire×Landrace]) weaned at 21 days of age were used in a randomized complete block design with 2×3 factorial arrangement. Pigs were assigned to three boron treatments (0, 5, and 10 mg/kg) under two environments (good and poor sanitary) to give six replicates per treatment (3 pigs per replicate). On 0, 7, and 14 days, one pig per replicate was euthanized to collect, ileum tissue samples, and rectal fecal samples.Results: Boron supplementation quadratically influenced (p<0.001) feed intake and weight gain in pigs housed in good sanitary conditions from 1 to 14 days post-weaning where pigs offered 5 mg/kg boron optimized weight gain and feed intake. There is a quadratic interaction (p = 0.019) on feed intake for 1 to 14 days post-weaning where 5 mg/kg boron increased feed intake in good sanitary conditions. Pigs housed in the poor sanitary environment decreased (p<0.001) villus height and crypt depth in ileum at days 7 and 14. On day 7 and 14, crude protein digestibility was quadratically influenced (p<0.05) by boron supplementation. Boron supplementation linearly increased (p<0.05) plasma calcium and cholesterol levels whilst linearly (p = 0.005) reducing plasma triglyceride concentrations. Diarrhea index was quadratically influenced (p<0.05) by boron supplementations regardless of sanitary conditions where 5 mg/kg boron inclusion achieved the lowest diarrhea index.Conclusion: Pigs offered 5 mg/kg of boron increased weight gain which may be deduced by improved dry matter, crude protein, and energy digestibility regardless of the sanitary conditions.

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