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      • 韓國産 자작나무科의 系統分類學的 硏究(序論)

        李相泰,蘇雄永,田寬培,李愚喆 全北大學校 生物學硏究所 1981 生物學硏究年報 Vol.2 No.-

        The present paper is an introduction to the whole project of "The systematic studies on Korean Betulaceae". Three studies under the project were performed this year and presented in this report : a review of taxonomic literatures and the construction of distribution maps by Woo-Tchul Lee, pollen morphology by Sang-Tae Lee and Moo-Yeol Kim, and wood anatomy by Woong-Young Soh and Kwan-Bae Jeon.

      • KCI등재후보

        Toluene, Xylene, Trichloroethylene 투여가 흰쥐의 시상하부와 뇌하수체의 GnRH, GnRH Receptor, Pit-1 유전자 발현에 미치는 영향

        기노석,이종태,강대성,김대환,이채관,이헌,전진호,김정호,이채언 大韓産業醫學會 1998 대한직업환경의학회지 Vol.10 No.2

        The workplace exposure of chemicals has steadily increased, therefore the concern for subsequent effect on reproductive outcome has been an important issue in occupational medicine. In previous studies, higher rates of spontaneous abortion, reduced fertility and menstrual disorder among women, and an impairement of sperm quantity and quality among men have been associated with a wide variety of chemical agents. This study was conducted to evaluate the effects of toluene, xylene and trichloroethylene(TCE) injection on the mRNA levels of GnRH, GnRH receptor and Pit-1 genes in male rats hypothalamus and pituitary and the effects on the plasma levels of FSH, LH, prolactin and testosterone. Sprague-Dawley male rats were divided into five groups of five each according to concentration of toluene, xylene and TCE. The rats were injected subcutaneously to 0, 50, 100, 200, 400 mg/kg body weight/day of toluene, xylene and TCE, respectively for 6 days. Rat brains were excised and hypothalamus and pituitary were separated. Reverse transcription-polymerase chain reaction (RT-PCR) and RNase protection assay(RPA) were used to evaluate the GnRH, GnRH receptor and Pit-1 mRNA levels. Plasma concentrations of FSH, LH, prolactin and testosterone were assayed by radioimmunoassay(RIA). The results were as follows; 1. GnRH, GnRH receptor and Pit-1 mRNA levels in toluene and xylene injected groups, and GnRH receptor mRNA levels in TCE injected group were lowered dose-dependently. Especially, GnRH receptor and Pit-1 mRNA levels in 200mg/kg of toluene injected group, and GnRH, GnRH receptor and Pit-1 mRNA levels in 400mg/kg of toluene injected group were significantly lower than control group (p<0.05). GnRH receptor and Pit-1 mRNA levels in 400mg/kg of xylene injected group, and GnRH receptor mRNA levels in 400mg/kg of TCE injected group were significantly lower than control group(p<0.05). 2. The plasma levels of prolactin and testosterone in 400mg/kg of toluene injected group, and LH in 100, 200 and 400mg/kg of xylene injected group, and testosterone in 400 mg/kg of TCE injected group were significantly lower than control group(p<0.05). In conclusion, we speculated that toluene and xylene affected reproductive system secondarily through hypothalamus-pituitary axis, and TCE affected directly through steroidogenesis. And we recommended that further study for assessment of the reproductive toxicity of mixed organic solvent exposures should be conducted.

      • KCI등재후보

        Discordance in Spirometric Interpretations Based on Korean and Non-Korean Reference Equations

        Nami Kim,Mi-Hee Park,Se-yeong Kim,Chunhui Suh,Sangyoon Lee,Kun-Hyung Kim,Chae-Kwan Lee,Dae-Hwan Kim,Jong-Tae Lee 대한직업환경의학회 2013 대한직업환경의학회지 Vol.25 No.-

        Objectives: Korean regression models for spirometric reference values are different from those of other ethnic groups. The purpose of this study was to evaluate discordance in spirometric interpretations based on using Korean reference equations versus non-Korean reference equations. Methods: Spirometry was performed on 825 Korean male workers from April 2009 to November 2011. The spirometric patterns and disease severity were evaluated using two Korean equations (Choi’s and Lee’s) and three equations for Caucasians (NHANES III, Morris’s, and Knudson’s), and the results of Choi’s equation were compared with the non-Korean equations. The spirometric patterns were defined as normal, restrictive, and mild and moderate obstructive. Results: The mean differences in the FEV1% and FVC% between the two Korean equations were 2.0 ± 1.3% and 3.5 ± 2.2%, respectively. Morris’s equation had the greatest difference in the FEV1% from Choi’s equation: 32.9 ± 8.5%. Knudson’s equation had the greatest difference in the FVC% from Choi’s equation: 10.5 ± 6.5%. Conclusions: The two Korean equations shared similar characteristics of spirometric interpretation. The spirometric interpretations of Choi’s equation were significantly different from those of Morris’s equation and Knudson’s equation.

      • 체육교사의 자기수업장학이 교수행동에 미치는 영향

        이병익,김관현,김진표,김기환,김윤태 龍仁大學校 2001 용인대학교 논문집 Vol.19 No.-

        This study was to analyze the effect of psical teacher's self-directed super- vision on teaching behavior. The prpose of this study is to identify the effect of pysical teacher's self director supervision of their teaching trough other teacher's teaching and all of physical education methods. Therefore research models and hypothesis were established on previous research and theories. Background variable was physical teacher's personal factor and Independent variable was physical teacher's sect-directed supervision. Dependent variable was teaching behavior of physical teacher. The data were collected by using simple random sampling of 360 physical teacher's in Seoul , Kyung-gi-Do, and In-chun. To survey the data question paper was used. T-test and one-way ANOVA were used to test hypothesis. Multiple-Regression Analysis was used to know effect of physical teacher's self-directed supervision on teaching behavior. Each hypothesis was tested at the significance level of 0.5 The conclusions were drawn as the followings First. influence of self- directed supervision by physical teacher's personal factor was following. According to sender there was no difference in teaching behavior. There was a significant influence in understanding students according to school's situation(girls, boys, and co-ed). There was a significant influence in class managing, understanding students, class preparing, teaching method according to class reflection. Second. influence of teaching behavior by physical teacher's personal factor was following influence. The gender had influence on dynamism and creativity. School situation(boys, girls, co-ed) had influence on individuality and creativity. Class reflection had influence on dynamism, creativity, obviousness and individuality. Third. effect of physical teacher's self-directed supervision on teaching behavior was followings. In dynamism, it had influence on teaching method, class managing, understanding students, sequentially. But not on preparation. In Individuality, it had influence on preparation, understanding students. Class managing sequentially. But not on teaching method. In obviousness. It had influence on class managing and Preparation. sequentially. but not on understanding students. and teaching method. In creativity, it had influence on understanding students, preparation, class manacling sequentially, but not on teaching method.

      • 전달행렬에 의한 탄성지반에 놓인 축대칭 원추-원통형 탱크 해석

        이관희,정성태,박준용,남문희 慶尙大學校生産技術硏究所 1997 生産技術硏究所論文集 Vol.13 No.-

        Even though there are many analysis methods of circular tanks on elastic foundation, the finite element method requires a number of memory spaces computation time to solve large stiffness equations, In this study many the simplified methods are applied to analyze a cone-cylinder tank on elastic foundation. By the given analysis methods, direct stiffness method and foundation matrix method, the con-cylinder tank was transformed into the skeletonized frame structure. The frame structure was drivided into several finite elements. The stiffness matrix of a finite element is related with the transfer matrix of the element. Thus, the transfer matrix of each finite element utilized the transfer matrix method to simplify the analysis of the tank. There were no significant difference in the results of two methods, the finite element method and the transfer matrix method. The transfer matrix method applied to a circular tank on elastic foundation resulted in four simultaneous equations to solve completely

      • SCOPUSKCI등재

        고정상세포분리기의 개발 및 Cyclosporin A 생산을 위한 고정화 연속배양공정에의 적용

        이태호,박성관,장용근,전계택 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.6

        균사형성 미생물인 고정상곰팡이의 연속배양공정에 필수적인 효율적인 고정상세포분리기를 개발하고 이를 실제로 면역억제제인 cyclosporin A(CyA) 연속생산공정에 적용하였다. 점성이 큰 고분자인 carboxymethyl cellulose 용액을 이용한 실험에서 개발된 고정상 세포분리기는 분리능이 우수하여 고점도·고유속의 경우에도 고정성담체가 거의 유실되지 않았다. 이는 고정상세포분리기내에 설치된 공기유출관과 분리관의 역할에 기인하는 것으로 보인다. 또한 실제 곰팡이 세포를 이용한 고정상 연속배양(IPRS)의 경우 고정상세포분리기를 설치함으로써 담체밀도의 감소와 배양액내의 고농도(10g/l) 현탁 곰팡이 세포의 존재에도 불구하고 안정한 조업가능성을 보였다. 고정상 연속배양의 높은 희석속도에도 불구하고 균체 및 CyA의 생산성이 높게 나타났으며, 담체가 반응기 밖으로 거의 유출되지 않은 점으로 보아 고정상세포분리기의 우수한 성능 및 조업안정성을 확인할 수 있었다. We have developed an efficient immobilized cell separator for continuous operation of immobilized fungal cell cultures, and applied this separator to actual fermentation process for the production of cyclosporin A (CyA), a powerful immunosuppressant. In the experiments employing highly viscous polymer (carboxymethyl cellulose) solution, the decantor showed good separating performances at high solution viscosites and fast dilution rates. Air duct and cylindrical separator installed inside the decantor turned out to play key roles for the efficient separation of the immobilized cells. By installing the decantor in an immobilized perfusion reactor system (IPRS), continuous immobilized culture was stably carried out even at high dilution rate for a long period, leading to high productivities of free cells and CyA. Almost no immobilized biomass existed in effuluent stream of the IPRS, demonstrating the effectiveness of the decantor system for a long-term continuous fermentation. It was noteworthy that we could obtain these results despite of the unfavorable fermentation conditions, i.e., reduced density of the biosupports caused by overgrowth of cells inside the bead particles and existence of high density of suspended fungal ells (10 g/l) in the fermentation broth.

      • SCOPUSSCIEKCI등재

        두개저 골절 환자의 임상적 고찰

        이용성,송시헌,김성호,김관태,김윤 대한신경외과학회 1994 Journal of Korean neurosurgical society Vol.23 No.9

        The authors analyzed 147 cases of basal skull fracture which were treated in the Department of Neurosurgery, Chungnam National University Hospital from Janwuy 1989 to December 1992. These fractures are difficult to diagnose by ordinary X-ray examination and are freguently inferred by clinical signs. The clinical features and radiological findings were reviewed. The results of the analysis are summarized as follows 1) The basal skull fractures were more common in men than women-the ratio being 6 1 1. 2) In decreasing order of cause of basal skull fractures were traffic accident~(77%), fall down, assault and slipping. 3) The minor head injury, Glasgow Coma Scale Score(GCS) of 13 to 15, was 79 cases(54%), the moderate head injury 40 cases(27%) and the severe head injury 18 cases(1996). 4) In decreasing order of clinical features were otorrhea(71 I) rhinorrhea(4856) and raccoon eye(33%) etc. 5) In decreasing order of the combined pathologies were skull fracture(55I 1, subdural hema-toma(l7%), epidural hematoma(l6%) and intraerebral hematoma(l2I) etc. 6) The facial nerve, vestibulocochlear nerve and optic nerve were the most commonly injured cranial nerve. 7) CSF leakage was noted in 139 cases and among them immediate type was far more common(%%) than the delayed type. 8) The incidence of meningitis was 5.4% and most of them associated with CSF leakage and the prophylatic antibiotic treatment has no effect to decrease infection rate. 9) In decreasing order of the frequency associated injuries were facial bone fracture (47%), clavicle fracture(19%), lower extremitics fracture(9%) and upper extremcties fracture(7%) etc.

      • SCOPUSSCIEKCI등재

        천측두동맥에 발생한 가성동맥류 1예

        이광태,김성호,송시헌,김관태,김윤 대한신경외과학회 1992 Journal of Korean neurosurgical society Vol.21 No.4

        The authors report a case of false aneurysm of the superficial temporal artery which manifested after operation for FCCD. An aneurysm of the superficial temporal artery is a rare disease. In collected literature, the incidence of superficial temporal artery aneurysms ranged from 0.5 to 2.5 percent of all aneurysms for which surgery was performed. False aneurysm should be suspected when a mass, which may or may not be pulsatile, appears in the scalp region after recent trauma. Troublesome(but not life-threatening) bleeding may occur if the lesion is unrecognized, and an attempt is made to "shell it out" as though it were an epidermal inclusion cyst.

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