http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Endoscopic management of ampullary neoplasm
Sunguk Jang 소화기인터벤션의학회 2019 International journal of gastrointestinal interven Vol.8 No.3
Neoplastic lesions of ampulla, although infrequent, represent a significant portion of precancerous lesions arising within duodenum. Occurring either as sporadic, solitary lesion, or as a part of multiple adenomas within duodenum, due to its potential for malignant transformation, ampullary adeno-ma warrants a careful evaluation with the intention of curative resection when possible. The removal of ampullary lesion can be accomplished either surgically, or endoscopically if feasible. Here, we provide a brief review of endoscopic management of ampullary neoplasm.
Endoscopic management of ampullary neoplasm
Sunguk Jang 소화기인터벤션의학회 2019 Gastrointestinal Intervention Vol.8 No.3
Neoplastic lesions of ampulla, although infrequent, represent a significant portion of precancerous lesions arising within duodenum. Occurring either as sporadic, solitary lesion, or as a part of multiple adenomas within duodenum, due to its potential for malignant transformation, ampullary adeno-ma warrants a careful evaluation with the intention of curative resection when possible. The removal of ampullary lesion can be accomplished either surgically, or endoscopically if feasible. Here, we provide a brief review of endoscopic management of ampullary neoplasm.
Novel Therapeutic Strategies in the Management of Non-Variceal Upper Gastrointestinal Bleeding
Ari Garber,Sunguk Jang 대한소화기내시경학회 2016 Clinical Endoscopy Vol.49 No.5
Non-variceal upper gastrointestinal bleeding, the most common etiology of which is peptic ulcer disease, remains a persistent challenge despite a reduction in both its incidence and mortality. Both pharmacologic and endoscopic techniques have been developed to achieve hemostasis, with varying degrees of success. Among the pharmacologic therapies, proton pump inhibitors remain the mainstay of treatment, as they reduce the risk of rebleeding and requirement for recurrent endoscopic evaluation. Tranexamic acid, a derivative of the amino acid lysine, is an antifibrinolytic agent whose role requires further investigation before application. Endoscopically delivered pharmacotherapy, including Hemospray (Cook Medical), EndoClot (EndoClot Plus Inc.), and Ankaferd Blood Stopper (Ankaferd Health Products), in addition to standard epinephrine, show promise in this regard, although their mechanisms of action require further investigation. Non-pharmacologic endoscopic techniques use one of the following two methods to achieve hemostasis: ablation or mechanical tamponade, which may involve using endoscopic clips, cautery, argon plasma coagulation, over-the-scope clipping devices, radiofrequency ablation, and cryotherapy. This review aimed to highlight these novel and fundamental hemostatic strategies and the research supporting their efficacy.
Single Use (Disposable) Duodenoscope: Recent Development and Future
Kihyun Ryu,Sunguk Jang 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.2
Unlike simple forward-viewing endoscopes such as gastroscope or colonoscope, duodenoscope houses much more complex designto fulfil its function. This design differences leave duodenoscopes more prone to contamination from inadequate disinfection processand potential dissemination of pathogens. Recent reports on dissemination of infection through the duodenoscope mandated anoverhaul of duodenoscope utilization including development of a disposable duodenoscope. This article reviews the current state ofdisposable duodenoscope development, including reported early efficacy as well as its future direction and utilization.
Endoscopic Hemostasis for Non-Variceal Upper Gastrointestinal Bleeding: New Frontiers
Adam Kichler,Sunguk Jang 대한소화기내시경학회 2019 Clinical Endoscopy Vol.52 No.5
Non-variceal upper gastrointestinal bleeding (NVUGIB) refers to blood loss from the gastrointestinal tract proximal to the ligamentof Treitz due to lesions that are non-variceal in origin. The distinction of the bleeding source as non-variceal is important in numerousaspects, but none more so than endoscopic approaches for successful hemostasis. When a patient presents with acute overt bloodloss, NVUGIB is a medical emergency, which requires immediate intervention. There have been major strides in pharmacologic andendoscopic interventions for successful induction and remission of hemostasis in the last two decades. Despite achieving tangibleimprovements, the burden of the disease and the consequent mortality remain high. To address endoscopic outcomes better, severalnew technologies have emerged and have been subsequently incorporated to the armamentarium of hemostatic tools. This study aimsto provide a succinct review on novel technologies for endoscopic hemostasis.
Future Perspectives on Endoscopic Ultrasonography-Guided Therapy for Pancreatic Neoplasm
Woo Hyun Paik,이상협,Sunguk Jang 대한소화기내시경학회 2018 Clinical Endoscopy Vol.51 No.3
Endoscopic ultrasonography (EUS)-guided therapy with ethanol injection or catheter-based radiofrequency ablation for pancreaticneoplasm has been conducted as a potential alternate treatment modality for patients who are not eligible for surgery. On the basis ofthe limited number of studies available, EUS-guided ablation therapy with the aforementioned methods for small pancreatic neoplasmshas demonstrated promising technical feasibility and safety profiles. To be considered as a legitimate alternative option to surgery,however, EUS-guided ablation therapy must provide a long-term efficacy profile along with the consensus among experts regarding itstreatment parameter. This review focuses on the clinical issues and future perspectives of EUS-guided therapy for pancreatic neoplasm.
Matheus Cavalcante Franco,Sunguk Jang,Bruno da Costa Martins,Tyler Stevens,Vipul Jairath,Rocio Lopez,John J. Vargo,Alan Barkun,Fauze Maluf-Filho 대한소화기내시경학회 2022 Clinical Endoscopy Vol.55 No.2
Background/Aims: Few studies have measured the accuracy of prognostic scores for upper gastrointestinal bleeding (UGIB)among cancer patients. Thereby, we compared the prognostic scores for predicting major outcomes in cancer patients with UGIB. Secondarily, we developed a new model to detect patients who might require hemostatic care. Methods: A prospective research was performed in a tertiary hospital by enrolling cancer patients admitted with UGIB. Clinical andendoscopic findings were obtained through a prospective database. Multiple logistic regression analysis was performed to gauge thepower of each score. Results: From April 2015 to May 2016, 243 patients met the inclusion criteria. The AIMS65 (area under the curve [AUC] 0.85) bestpredicted intensive care unit admission, while the Glasgow-Blatchford score best predicted blood transfusion (AUC 0.82) and thelow-risk group (AUC 0.92). All scores failed to predict hemostatic therapy and rebleeding. The new score was superior (AUC 0.74)in predicting hemostatic therapy. The AIMS65 (AUC 0.84) best predicted in-hospital mortality. Conclusions: The scoring systems for prognostication were validated in the group of cancer patients with UGIB. A new score wasdeveloped to predict hemostatic therapy. Following this result, future prospective research should be performed to validate the newscore.