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3차원 탄소성 유한요소법을 통한 금속복합재료와 지르코니아 접합체의 잔류응력해석
주재황,선동주,최영택,박세만,박명균 明知大學校 産業技術硏究所 1996 産業技術硏究所論文集 Vol.15 No.-
Employing a three dimensional finite element method a thermal elasto-plastic stress analysis was conducted to investigate residual stress distributions on the joining area between a ceramic(ZrO₂) and a SiC whisker-reinforced aluminum (Al composite). For purposes of comparisons, residual stresses at the interfaces on the joining area were first analyzed for varying volume fractions of SiC whiskers utilizing two dimensional elasto-plastic models. The results from the 2-D models were compared with those from 3-D models to understand the Practical nature of residual stresses produced during industrial joining processes for ceramics and metal matrix composites. Additionally, the same procedures were applied to compute stress variations along a line passing through the joining area to obtain a physical insight and to offer a plausible explanations for fracture patterns occuring at the interfaces during bending.
Korean Cancer Study Group,Ji, J.H.,Yun, T.,Kim, S.B.,Kang, J.H.,Park, J.C.,Cho, I.S.,Sohn, C.H.,Heo, D.S.,Jang, J.S.,Shin, S.W.,Hwang, D.W.,Sun, J.M.,Park, K.,Ahn, M.J. Pergamon Press 2012 European journal of cancer Vol.48 No.17
Background: The purpose of this phase II study was to determine the efficacy and toxicity of cisplatin and weekly docetaxel combination chemotherapy as a first-line treatment in patients with recurrent or metastatic nasopharyngeal cancer. Patients and Methods: Recurrent or metastatic nasopharyngeal cancer patients were enrolled and received a combination of weekly docetaxel (35mg/m<SUP>2</SUP> on Day1 and Day8) and cisplatin (70mg/m<SUP>2</SUP> D1) every 21days, for up to a maximum of 6 cycles. The primary endpoint was objective response rate, and the secondary endpoints included toxicity of combination chemotherapy, progression-free survival, overall survival and 1-year survival rate. Results: In total, 47 patients were enrolled and analysed, and 46 patients (97.9%) completed the planned protocol. In an intent-to-treat analysis, 6 patients (12.8%) achieved complete response (CR) and 27 patients (57.4%) showed partial response (PR), with an objective response rate of 70.2%. The median progression-free survival and overall survival were 9.6months (95% C.I. 5.7-13.5months) and 28.5months (95% C.I. 16.9-40.1months), respectively, and the 1-year survival rate was 89.9%. The common grade 3 adverse events were stomatitis (1.2%), neutropenia (0.8%), anaemia (0.8%), infection (0.8%) and diarrhoea (0.8%). Grade 4 adverse events were not observed in this study. Conclusions: The combination chemotherapy of cisplatin and weekly docetaxel is highly effective and shows favourable toxicity as a first-line chemotherapy in patients with recurrent or metastatic nasopharyngeal cancer.
원발성 간암에서 PIVKA-II 및 Lens Culinaris Agglutinin-A 반응성 Alpha-fetoprotein(AFP-L3)의 임상적 유용성
배시현,박두호,양진모,박영민,차상복,최종영,성광용,조세현,정규원,선희식,김부성,최상욱,변병훈,한남익 대한간학회 2000 Clinical and Molecular Hepatology(대한간학회지) Vol.6 No.2
Background/Aims: Des-γ-carboxy prothrombin(DCP), a protein induced by vitamin K absence or antagonist-II(PIVKA-II), and Lens culinaris agglutinin-A reactive AFP-L3 have been reported to be useful markers for the diagnosis of hepatocellular carcinoma (HCC). In the present study, both the PIVKA-II and AFP-L3 were analyzed and compared with a conventional AFP to determine its usefulness, specificity and sensitivity in the diagnosis of HCC. Methods: Sera were collected from 108 patients consisting of 17 patients with chronic hepatitis, 22 patients with liver cirrhosis and 69 patients with HCC. The AFP-L3 was determined by an lectin affinity electrophoresis coupled with an antibody-affinity blotting. Level of DCP was measured by an enzyme immunoassay with an anti-DCP monoclonal antibody. Results: The sensitivity and specificity of PIVKA-II and AFP L3 were 49.3% and 89.5%, and 32.5% and 85.7%, respectively. No significant correlation was found between the PIVKA-II or AFP L3 and serum AFP. No correlation was found etween the PIVKA-II or AFP L3 and the characteristics of HCC. Conclusion: The determination of plasma DCP and AFP L3 levels combined with AFP levels may be useful especially for the differential diagnosis between HCC and chronic liver diseases without HCC.(Korean J HepatoBackground/Aims: Des-γ-carboxy prothrombin(DCP), a protein induced by vitamin K absence or antagonist-II(PIVKA-II), and Lens culinaris agglutinin-A reactive AFP-L3 have been reported to be useful markers for the diagnosis of hepatocellular carcinoma (HCC). In the present study, both the PIVKA-II and AFP-L3 were analyzed and compared with a conventional AFP to determine its usefulness, specificity and sensitivity in the diagnosis of HCC. Methods: Sera were collected from 108 patients consisting of 17 patients with chronic hepatitis, 22 patients with liver cirrhosis and 69 patients with HCC. The AFP-L3 was determined by an lectin affinity electrophoresis coupled with an antibody-affinity blotting. Level of DCP was measured by an enzyme immunoassay with an anti-DCP monoclonal antibody. Results: The sensitivity and specificity of PIVKA-II and AFP-L3 were 49.3% and 89.5%, and 32.5% and 85.7%, respectively. No significant correlation was found between the PIVKA-II or AFP-L3 and serum AFP. No correlation was found etween the PIVKA-II or AFP L3 and the characteristics of HCC. Conclusion: The determination of plasma DCP and AFP-L3 levels combined with AFP levels may be useful especially for the differential diagnosis between HCC and chronic liver diseases without HCC.(Korean J Hepatol 2000;6:205-214)l 2000;6:205-214)
有限要素法을 이용한 열사이클 荷重壯態에서의 세라믹 /金屬 接合材의 强度 平價
최영택,박명균,박세만,선동주 明知大學校 産業技術硏究所 1998 産業技術硏究所論文集 Vol.17 No.-
In this work, variations of residual stresses are investigated by varying thicknesses of copper interlayers inserted for stress relaxations. Futhermore, various modes of stress distributions are evaluated under different assumptions of physical situations. departing from the simple assumption and adopting new assumption is judiciously made to study variations of residual stresses under the simple and new assumption, respectively. The simple assumption dictates that temperature distributions in the ceramic/metal joints are uniform, which amounts to longer cooling time (slow cooling), while the new assumption relaxes the condition of uniform temperature distributions allowing variations of temperatures in the ceramic/metal joints. Especially, the thermal cycles are applied to ceramic/metal joints retaining residual stresses developed during joining processes. Changes in distributions of residual stresses under the applied thermal cycles and the behavior of ceramic/ metal joints formed at elevated temperatures are evaluated from finite element analysis to produce results in good agreement with the existing experimental data.
KMT-2017-BLG-0165Lb: A Super-Neptune-mass Planet Orbiting a Sun-like Host Star
Kil Jung, Youn,Gould, Andrew,Zang, Weicheng,Hwang, Kyu-Ha,Ryu, Yoon-Hyun,Han, Cheongho,Yee, Jennifer C.,Albrow, Michael D.,Chung, Sun-Ju,Shin, In-Gu,Shvartzvald, Yossi,Zhu, Wei,Cha, Sang-Mok,Kim, Dong American Astronomical Society 2019 The Astronomical journal Vol.157 No.2
유한요소법을 이용한 금속재료의 탄소성파괴인성치 결정에 관한 연구
박명균,최영택,박세만,선동주 明知大學校 産業技術硏究所 1998 産業技術硏究所論文集 Vol.17 No.-
In oder to predict the elastic-plastic fracture toughness for metallic materials, Finite element Method(FEM) was used for analysis of compact tension specimen. ASTM E399 test procedure was adopted for simulation of FEM. The Load-Crack Mouth Opening Displacement curve obtained from this analysis was used to detect the crack initiation point and determine the elastic-plastic fracture toughness Jic. In order to prove the results, they were compared with the results from previous experiments and they agree with experimental results.
Alahakoon, Amali U.,Jayasena, Dinesh D.,Jung, Samooel,Kim, Hyun Joo,Kim, Sun Hyo,Jo, Cheorun Korean Society for Food Science of Animal Resource 2014 한국축산식품학회지 Vol.34 No.2
Chicken breast meat was injected with calcium chloride alone and in combination with lactic acid (0.01% and 0.002%, respectively). The inhibitory effects of the treatments on microbial growth were determined in the injected chicken breast meat stored at $4^{\circ}C$ under aerobic packaging condition for 0, 3, and 7 d. Calcium chloride combined with 0.002% and 0.01% lactic acid reduced microbial counts by 0.14 and 1.08 Log CFU/g, respectively, however, calcium chloride alone was unable to inhibit microbial growth. Calcium chloride combined with 0.01% lactic acid was the most effective antimicrobial treatment and resulted in the highest initial redness value. Calcium chloride alone and combined with lactic acid suppressed changes in pH and the Hunter color values during storage. However, injection of calcium chloride and lactic acid had adverse effects on lipid oxidation and sensory characteristics. The higher TBARS values were observed in samples treated with calcium chloride and lactic acid when compared to control over the storage period. Addition of calcium chloride and lactic acid resulted in lower sensory scores for parameters tested, except odor and color, compared to control samples. Therefore, the formulation should be improved in order to overcome such defects prior to industrial application.
기관식도루·우심증·우측폐형성부전을 동반한 식도폐쇄증 1례
한창규,이강일,김춘동,배선익 순천향대학교 1988 논문집 Vol.11 No.1
Esophageal atresia associated with tracheoesophageal fistula is a congenital anomaly of primitive foregut development, which induces the respiratory distress in the early newborn period. There are many reports about development on treatment of this abnormality in foreign countries, but in this country its survival rate is very low until now. Authers have experienced a case of the esophageal atresia which is associated with dextrocardia. right pulmonary aplasia and tracheoesphageal fistula. We present the case and review the related literatures briefly.
Brazing 과 Metallizing 에 의한 세라믹/금속 접합재 잔류응력의 유한요소 해석
최영택,박명균,박세만,선동주 명지대학교 대학원 1997 대학원논문집 Vol.1 No.-
In this study finite element method(FEM) is utilized to determine residual stress distributions induced by heat generated during joining processes of ceramics and metals. The finite element analysis is focused on the joining area, that comprises the interfacial area between a metal and a insert-layer, the insert-layer itself and adjoining area between the insert-layer and a ceramic. The residual stress distributions on the joining area are analyzed as function of thicknesses and yield stresses of the insert-layer(Brazing Filler Metal), and for different kinds of metals including SUS304 and SM45C. Two typical joining processes are considered in this investigation ; Active Metal Brazing and Metallizing. Stress distributions on the joining areas are computed for both processes and are compared with one another. This comparison can lead to the better joining method in reducing the residual stresses and consequently provide improved joining technologies.