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Eda Ayse Aksoy,Betul Suyumbike Yagci,Gulseher Manap,Ipek Eroglu,Sukru Ozturk,Melike Ekizoglu,Kezban Ulubayram 한국섬유공학회 2019 Fibers and polymers Vol.20 No.11
In this study, it was aimed to develop drug eluting biodegradable and biocompatible bone supportive fibers andfilms, which can locally be applicable on the infected bone defect area for osteomyelitis treatment. For this purpose,vancomycin (Vm) loaded gelatin (G) microspheres were prepared and dispersed into poly(ε-caprolactone) (PCL) solutionand then the suspension was processed as films and fibers by solvent casting and wet spinning techniques, respectively. Themean particle size distribution and morphology of Vm loaded G microspheres were characterized by laser diffraction methodand scanning electron microscopy, respectively. In vitro Vm release profiles and release kinetics from microsphere, fiber andfilm formulations were investigated. In vitro biodegradation properties of fiber and film formulations were examined in bothhydrolytic and enzymatic media during 25 days period. The cytotoxicity of Vm eluting films and fibers were tested on L929cells by MTT assay. Presence of PCL in film and fiber formulations retarded the release of Vm from microspheres andprovided long term sustained release. Vm eluting films and fibers exhibited strong antibacterial properties againstStaphylococcus aureus and Staphylococcus epidermidis.
Nuri Karadurmus,Selmin Ataergin,Gokhan Erdem,Mustafa Cakar,Ozdes Emer,Sukru Ozaydin,Mustafa Ozturk,Mukerrem Safali,Fikret Arpaci 대한암학회 2013 Cancer Research and Treatment Vol.45 No.3
The central nervous system (CNS) is an important area of involvement for both highgrade,aggressive primary and secondary lymphomas. Although follicular lymphoma represents a low-grade histology, it may rarely present with CNS involvement. Here,we describe a patient diagnosed with follicular lymphoma who was presented with cerebellar involvement.
Eyelid Tumors: Clinical Data from an Eye Center in Ankara, Turkey
Gundogan, Fatih Cakir,Yolcu, Umit,Tas, Ahmet,Sahin, Omer Faruk,Uzun, Salih,Cermik, Hakan,Ozaydin, Sukru,Ilhan, Abdullah,Altun, Salih,Ozturk, Mustafa,Sahin, Fahri,Erdem, Uzeyir Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10
Introduction: The aim of the study was to explore the distribution of eyelid tumors in Ankara, the capital city of Turkey, from a histopathological point of view. Materials and Methods: Medical records of 1,502 patients who had eyelid surgery because of tumoral lesions were retrospectively reviewed after obtaining institutional review board approval. A total of 1,541 lesions with histopathologic diagnosis were included. Inflammatory tumoral lesions were excluded. The lesions were categorized into three groups according to the origin: epidermal, adnexal tumors and 'others', including melanocytic, neural and vascular lesions. Results: Of the total of 1,541, 908 lesions were epidermal in origin. Only 22 (1.5%) were malignant, and 6.0% was premalignant lesions such as actinic keratosis and Bowen's disease. Twenty-one of 22 malignant lesions were basal cell carcinoma. There was only one patient with squamous cell carcinoma and no sebaceous cell carcinoma. Among the benign tumors (92.5%), squamous papilloma was the most frequent (21.8% of all lesions). The other frequent lesions were nevus (17.6%), seborrheic keratosis (17.3%), hydrocystomas (10.6%), xanthelasma (7.6%) and epidermal cysts (7.2%). Conclusions: The results of this study are in accordance with published literature. The absence of sebaceous cell carcinomas needs to be stressed.