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Structural Behavior of KSTAR CS Magnet During Plasma Operation
Ahn, Hee-Jae,Park, Hyun-Ki,Kim, Jinsub,Kim, YoungOk,Kim, Kwang Pyo,Chu, Yong,Kim, Hyun-Seok,Park, Kaprai,Oh, Yeong-Kook,Lee, Sudo,Kim, Yong Hwan Institute of Electrical and Electronics Engineers 2018 IEEE transactions on applied superconductivity Vol.28 No.3
<P>The finite element model of KSTAR central solenoid (CS) magnet has been developed with new smeared orthotropic material properties of CS coils and the effective coefficient of thermal expansion of the magnet structures. The accuracy of structural analysis for assembly and cool-down processes is higher than in previous studies. Electromagnetic analysis was performed to evaluate Lorentz forces of poloidal field (PF) coils during a long pulse discharge. The analyzed structural behavior of the CS magnet was clearly consistent with the measured data and calculated Electromagnetic (EM) forces during the plasma operation. The current of PF4 coil had a significant effect on axial compression and the minimum preloading was maintained at 2.0 MN in the end of plasma. Equivalent EM force can easily predict the axial compression of CS magnet without complicated structural analysis. The study on the structural behavior of CS magnet is expected to provide the optimal combination of PF coil current limits for large plasma current and long pulse discharges.</P>
M-LEANING SYSTEM BASED ON CC/PP FOR MMS ADAPTATION
Sudo Kim,Mangon Park 한국멀티미디어학회 2007 한국멀티미디어학회 국제학술대회 Vol.2007 No.-
It becomes enabled to provide variety of multimedia contents through mobile service with the development of high-speed 3rd generation mobile communication and terminal units. MMS (Multimedia Messaging Service) can be displayed in the presentation format which is unified the various multimedia contents such as text, audio, image, video, etc. It is applicable as a new type of ubiquitous learning. This paper proposes m-learning system which can provides MMS learning contents that can be adapted to heterogeneous environments of learners. By providing profiles which meets the standard of CC/PP, it generates MMS based on SMIL language through the adaptation steps according to the learning environment, the content type, and the device property of learners.
Kanaya, Y.,Irie, H.,Takashima, H.,Iwabuchi, H.,Akimoto, H.,Sudo, K.,Gu, M.,Chong, J.,Kim, Y. J.,Lee, H.,Li, A.,Si, F.,Xu, J.,Xie, P.-H.,Liu, W.-Q.,Dzhola, A.,Postylyakov, O.,Ivanov, V.,Grechko, E.,Ter Copernicus GmbH 2014 Atmospheric Chemistry and Physics Vol.14 No.15
<P>Abstract. We conducted long-term network observations using standardized Multi-Axis Differential optical absorption spectroscopy (MAX-DOAS) instruments in Russia and ASia (MADRAS) from 2007 onwards and made the first synthetic data analysis. At seven locations (Cape Hedo, Fukue and Yokosuka in Japan, Hefei in China, Gwangju in Korea, and Tomsk and Zvenigorod in Russia) with different levels of pollution, we obtained 80 927 retrievals of tropospheric NO2 vertical column density (TropoNO2VCD) and aerosol optical depth (AOD). In the technique, the optimal estimation of the TropoNO2VCD and its profile was performed using aerosol information derived from O4 absorbances simultaneously observed at 460-490 nm. This large data set was used to analyze NO2 climatology systematically, including temporal variations from the seasonal to the diurnal scale. The results were compared with Ozone Monitoring Instrument (OMI) satellite observations and global model simulations. Two NO2 retrievals of OMI satellite data (NASA ver. 2.1 and Dutch OMI NO2 (DOMINO) ver. 2.0) generally showed close correlations with those derived from MAX-DOAS observations, but had low biases of up to ~50%. The bias was distinct when NO2 was abundantly present near the surface and when the AOD was high, suggesting a possibility of incomplete accounting of NO2 near the surface under relatively high aerosol conditions for the satellite observations. Except for constant biases, the satellite observations showed nearly perfect seasonal agreement with MAX-DOAS observations, suggesting that the analysis of seasonal features of the satellite data were robust. Weekend reduction in the TropoNO2VCD found at Yokosuka and Gwangju was absent at Hefei, implying that the major sources had different weekly variation patterns. While the TropoNO2VCD generally decreased during the midday hours, it increased exceptionally at urban/suburban locations (Yokosuka, Gwangju, and Hefei) during winter. A global chemical transport model, MIROC-ESM-CHEM (Model for Interdisciplinary Research on Climate-Earth System Model-Chemistry), was validated for the first time with respect to background NO2 column densities during summer at Cape Hedo and Fukue in the clean marine atmosphere. </P>
Yoon, Jeong-Hwan,Jung, Su Myung,Park, Seok Hee,Kato, Mitsuyasu,Yamashita, Tadashi,Lee, In-Kyu,Sudo, Katsuko,Nakae, Susumu,Han, Jin Soo,Kim, Ok-Hee,Oh, Byung-Chul,Sumida, Takayuki,Kuroda, Masahiko,Ju, Blackwell Publishing Ltd 2013 EMBO molecular medicine Vol.5 No.11
<P>Varieties of transforming growth factor-β (TGF-β) antagonists have been developed to intervene with excessive TGF-β signalling activity in cancer. Activin receptor-like kinase5 (ALK5) inhibitors antagonize TGF-β signalling by blocking TGF-β receptor-activated Smad (R-Smad) phosphorylation. Here we report the novel mechanisms how ALK5 inhibitors exert a therapeutic effect on a mouse B16 melanoma model. Oral treatment with a novel ALK5 inhibitor, EW-7197 (2.5 mg/kg daily) or a representative ALK5 inhibitor, LY-2157299 (75 mg/kg bid) suppressed the progression of melanoma with enhanced cytotoxic T-lymphocyte (CTL) responses. Notably, ALK5 inhibitors not only blocked R-Smad phosphorylation, but also induced ubiquitin-mediated degradation of the common Smad, Smad4 mainly in CD8<SUP>+</SUP> T cells in melanoma-bearing mice. Accordingly, T-cell-specific deletion of Smad4 was sufficient to suppress the progression of melanoma. We further identified eomesodermin (Eomes), the T-box transcription factor regulating CTL functions, as a specific target repressed by TGF-β via Smad4 and Smad3 in CD8<SUP>+</SUP> T cells. Thus, ALK5 inhibition enhances anti-melanoma CTL responses through ubiquitin-mediated degradation of Smad4 in addition to the direct inhibitory effect on R-Smad phosphorylation.</P>