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Yibo Han,Takanori Kida,Masami Ikeda,Masayuki Hagiwara,Jozef Streˇcka,Zentaro Honda 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12
A powder and field-aligned samples of the 3d-4f bimetallic polymeric chain[Dy(NO3)(DMSO)2Cu(opba)(DMSO)2, DMSO: Dimethyl-sulfoxide, opba: ortho-phenylenebis(oxalato)] built from alternating dysprosium(3+) and copper(2+) ions are magnetic investigatedin detail. The magnetic alignment for the powder is successful indicated by the remarkablemagnetic anisotropy at low temperature. The high-field magnetization of the powder sample wasmeasured at the temperatures down to 1.3 K and in magnetic fields up to 52 T. The high-fieldmagnetization of the powder sample is in reasonably accordance with theoretical predictions for aspin-1/2 chain of alternating Ising and Heisenberg spins. The present study thus provides the firsthigh-field investigation of a new type of Ising-Heisenberg spin alternating chain.
Schultz, Bruce T.,Teigler, Jeffrey E.,Pissani, F.,Oster, Alexander F.,Kranias, G.,Alter, G.,Marovich, M.,Eller, Michael A.,Dittmer, U.,Robb, Merlin L.,Kim, Jerome H.,Michael, Nelson L.,Bolton, D.,Stre Cell Press 2016 Immunity Vol.44 No.1
<P>A central effort in HIV vaccine development is to generate protective broadly neutralizing antibodies, a process dependent on T follicular helper (Tfh) cells. The feasibility of using peripheral blood counterparts of lymph node Tfh cells to assess the immune response and the influence of viral and vaccine antigens on their helper functions remain obscure. We assessed circulating HIV-specific IL-21(+) CD4(+) T cells and showed transcriptional and phenotypic similarities to lymphoid Tfh cells, and hence representing peripheral Tfh (pTfh) cells. pTfh cells were functionally active and B cell helper quality differed depending on antigen specificity. Furthermore, we found higher frequency of pTfh cells in peripheral blood mononuclear cell specimens from the ALVAC+AIDSVAX (RV144) HIV vaccine trial associated with protective antibody responses compared to the non-protective DNA+Ad5 vaccine trial. Together, we identify IL-21(+) CD4(+) T cells as pTfh cells, implicating them as key populations in the generation of vaccine-evoked antibody responses.</P>