Sensory Science for New Healthy and Palatable Tailor-Made Meal Solutions for Individuals Suffering from Taste Alterations

Sara Spinelli 한국식품영양과학회 2022 한국식품영양과학회 학술대회발표집 Vol.2022 No.10

Food Preferences and Obesity

Sara Spinelli,Erminio Monteleone 대한내분비학회 2021 Endocrinology and metabolism Vol.36 No.2

Obesity is a multifactorial disease with several potential causes that remain incompletely understood. Recent changes in the environment, which has become increasingly obesogenic, have been found to interact with individual factors. Evidence of the role of tasteresponsiveness and food preference in obesity has been reported, pointing to a lower taste sensitivity and a higher preference and intake of fat and, to a lesser extent, sweet foods in obese people. Studies in the last decades have also suggested that individual differences in the neurophysiology of food reward may lead to overeating, contributing to obesity. However, further studies are needed toconfirm these findings. In fact, only a limited number of studies has been conducted on large samples, and several studies were conducted only on women. Larger balanced studies in terms of sex/gender and age are required in order to control the confounding effect of these variables. As many factors are intertwined in obesity, a multidisciplinary approach is needed. This will allow a betterunderstanding of taste alteration and food behaviours in obese people in order to design more effective strategies to promote healthier eating and to prevent obesity and the related chronic disease risks.

Discovery of a trans-sellar vascular supply for the pituitary gland

Casey P. Spinelli,Joe Iwanaga,Mi-Sun Hur,Aaron S. Dumont,R. Shane Tubbs 대한해부학회 2022 Anatomy & Cell Biology Vol.55 No.2

the Digital Grand Tour

Monica Meini,Gianfranco Spinelli 세계문화관광학회 2008 Conference Proceedings Vol.9 No.0

The theme of travel is, at least in theory, a breeding ground of a meeting between the rationalist perspective and the humanistic or cognitive perspective in geography. Indeed the two approaches have often followed opposite routes, one being anchored to the objective description and the other reaching the subjectivism of behaviour geography. This article tries to fit in that multiple perspective which aims to reconcile rationalist and cognitive analysis, focusing on a multidimensional approach in the description and representation of places. This contribution seeks to experiment with new ways of spreading travel culture by using the specific instruments of the geographer. It is also an attempt to verify the reliability of the new means of expression and of the new multimedia techniques starting from proper geographical instruments such as GIS and basing hypertext flexibility on cartographic tangibility. We intend to clarify the reasons and the epistemological framework of our proposal and to analyse specific applications such as that we have realized with reference to a journey in the United States: the hypermap named Amerigo. The fundamental innovative aspect is the inclusion of the subjective dimension, coming from travel experience, within a system of objective references linked to geographical coordinates.

Metastatic Squamous Cell Carcinoma of the Lower Lip: Analysis of the 5-Year Survival Rate

Tommaso Agostini,Giuseppe Spinelli,Francesco Arcuri,Raffaella Perello 대한두개안면성형외과학회 2017 Archives of Craniofacial Surgery Vol.18 No.2

Background: The author analyse the impact of extracapsular lymph node spread and bone engagement in the ipsilateral neck of patients suffering squamous cell carcinoma (SCC) of the lower lip. Methods: The data of 56 neck dissections performed in patients suffering SCC of the lower lip between January 2000 and December 2008 were retrospectively analysed. Statistical analysis was performed with the Kaplan-Meier life table method, and the survival rate was investigated with the log rank statistic and significance test. The values were considered statistically significant at p<0.05. Results: Nine patients took advantage from simultaneous treatment of tumor and prophylactic neck dissection (level I–III), reaching 100% survival rate. Patients suffering metastasized disease, who received radical neck dissection at the time of tumor treatment, presented 83.3% survival rate. Patients who underwent previous surgery and radiotherapy presented worse prognosis although radical neck dissection in case of extra-capsular spread only (24.7%) and osseous engagement (22.2%). Conclusion: Prophylactic neck dissection (level I–III) is recommended in T3–T4 N0 SCC. Simultaneous treatment of tumor and cervical lymph nodes provides a better prognosis as respect to delayed nodal management. Extra-capsular spread with or without bone engagement represents independent risk factor responsible for high mortality rate of SCC of the lower lip.

Conventional Versus Biological Therapy for Prevention of Postoperative Endoscopic Recurrence in Patients With Crohn`s Disease: an International, Multicenter,and Observational Study

( Paulo Gustavo Kotze ),( Antonino Spinelli ),( Rodolff Nunes Da Silva ),( Ivan Folchini De Barcelos ),( Fabio Vieira Teixeira ),( Rogerio Saad Hossne ),( Idblan Carvalho De Albuquerque ),( Marcia Ola 대한장연구학회 2015 Intestinal Research Vol.13 No.3

Background/Aims: Postoperative endoscopic recurrence (PER) occurs in nearly 80% of patients 1 year after ileocecal resection in patients with Crohn`s disease (CD). Biological agents were more effective in reducing the rates of PER in comparison with conventional therapy, in prospective trials. The aim of this study was to compare the PER rates of biological versus conventional therapy after ileocecal resections in patients with CD in real-world practice. Methods: The MULTIPER (Multicenter International Postoperative Endoscopic Recurrence) database is a retrospective analysis of PER rates in CD patients after ileocecalresection, from 7 referral centers in 3 different countries. All consecutive patients who underwent ileocecal resections between 2008 and 2012 and in whom colonoscopies had been performed up to 12 months after surgery, were included. Recurrence was defined as Rutgeerts` score ≥i2. The patients were allocated to either biological or conventional therapy after surgery,and PER rates were compared between the groups. Results: Initially, 231patients were evaluated, and 63 were excluded. Of the 168 patients in the database, 96 received anti-tumor necrosis factor agents and 72 were treated with conventional therapy after resection. The groups were comparable regarding age, gender, and perianal disease. There was longer disease duration, more previous resections, and more open surgical procedures in patients on biologicals postoperatively. PER was identified in 25/96 (26%) patients on biological therapy and in 24/72 (33.3%) patients on conventional therapy (P =0.310). Conclusions: Inthis retrospective observational analysis from an international database, no difference was observed between biological and conventional therapy in preventing PER after ileocecal resections in CD patients. (Intest Res 2015;13:259-265)

Utilization of woody pruning residues of apple trees

Najibeh Gilanipoor,Rafaele Spinelli,Ramin Naghdi,Akbar Najafi 한국산림과학회 2020 Forest Science And Technology Vol.16 No.4

Utilize agricultural residues from pruning brings many advantages including employment, social and economic benefit, rural development, natural forest protection, increased energy efficiency, and lower costs of raw material for the production of particleboard industry. In this study, the use of wood utilization of pruning residues from apple trees has been investi�gated by using chipping at the landing chipping methods (LCMs) and farm chipping meth�ods (FCM). These methods were conducted on seven farms, totaling 9.2 ha. A time study was used to estimate operation time and cost. Transportation of chips from the study area to factories was done with semi-trailers, trucks, and pickup trucks. The residue yield was between 1.8 and 2.0 green ton per hectare. The maximum time was related to chipping and the collection of residues and the most delay was mechanical. The residues were collected, chipped, and transported to the particleboard factory at a cost between US$10.18 and US$19.46 per ton, and the profit rate between US$15.5 and US$24.8 per ton depending on chipping methods and secondary transport system. Cost and the total time of LCM were lower than the FCM, and also production rate of LCM was higher than the FCM; therefore, this method was more effective in processing residues from apple trees. Regression techni�ques showed that in LCM, the effect of diameter and age was significant on residue process�ing time and in FCM, the effect of diameter, age, residue density, and functional the area was significant in residue processing time.

Pinching in Steel Rack Joints: Numerical Modelling and Eff ects on Structural Response

Federico Gusella,Maurizio Orlando,Paolo Spinelli 한국강구조학회 2019 International Journal of Steel Structures Vol.19 No.1

The structural behaviour of beam-to-column joints plays a key role in the seismic response of frame structures. Regarding to steel storage pallet racks, experimental tests have highlighted that the hysteresis loop of their joints is characterized by the pinching, with the consequence of a reduction of the dissipated hysteretic energy and load carrying capacity. In this paper the authors propose a simplifi ed numerical pinching model capable to simulate the mechanical response of beam-tocolumn joints under cyclic loads. To develop and check this model, several comparisons are performed with both literature data and experimental results of laboratory tests. The proposed model is characterised by three links placed in parallel: two “composed links” describe the non-linear bending moment-rotation curve of the joint, and a linear elastic link transfers the axial and shear force from the beam to the column. The model is appropriate for predicting the down-aisle seismic response of rack systems and it can be easily implemented in commercial software packages, commonly used for non-linear seismic vulnerability analyses. Moreover, features of the model can be estimated from a few structural data and it does not require to perform expensive cyclic experimental tests. For a deeper understanding of the eff ects of pinching in the seismic response and to highlight the potentiality of the proposed model a case-study example is also considered. The case-study concerns a rack system, whose beam-to-column joints are modelled using two numerical approaches which diff er in the deterioration of the rotational stiff ness of joints. Non-linear dynamic analyses, with simulated ground acceleration time-histories, have been carried.

The Correlation Between Dendritic Microstructure and Mechanical Properties of Directionally Solidified Hypoeutectic Al-Ni Alloys

Manuel V. Canté,José E. Spinelli,Noé Cheung,Amauri Garcia 대한금속·재료학회 2010 METALS AND MATERIALS International Vol.16 No.1

Al-Ni hypoeutectic alloys were directionally solidified under upward transient heat flow conditions. The aim of the present study is to set up correlations between the as-cast microstructure and the resulting mechanical properties of these alloys. The dependence of primary and secondary dendrite arm spacing on the alloy solute content and on solidification thermal parameters is also analyzed. The results include transient metal/mold heat transfer coefficient, tip growth rate, cooling rate, dendrite arm spacing, ultimate tensile strength, yield tensile strength and elongation. Expressions relating dendrite spacing to solidification thermal parameters and mechanical properties to the scale of the dendritic microstructure have been determined. It was found that the ultimate tensile strength and the yield tensile strength increase with increasing alloy solute content and with decreasing primary and secondary dendrite arm spacing. In contrast, the elongation was found to be independent of both alloy composition and dendritic arrangement.

Experimental capacity of perforated cold-formed steel open sections under compression and bending

Maurizio Orlando,Giovanni Lavacchini,Barbara Ortolani,Paolo Spinelli 국제구조공학회 2017 Steel and Composite Structures, An International J Vol.24 No.2

This study evaluates the reliability of present European codes in predicting the collapse load of columns made with perforated cold-formed steel (CFS) profiles under combined axial load and bending. To this aim, a series of experimental tests on slender open-section specimens have been performed at varying load eccentricity. Preliminarily, stub column tests have also been performed to calculate the effective section properties of the investigated profile. By comparison of experimental data with code-specified M-N strength domains, the authors demonstrate that present code formulations may underestimate the collapse load of thin-walled perforated open sections. The study is the first step of a wider experimental and numerical study aimed at better describing strength domains of perforated CFS open sections.