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Flow-Aware Link Dimensioning for Guaranteed-QoS Services in Broadband Convergence Networks
Lee, Hoon,Sohraby, Khosrow The Korea Institute of Information and Commucation 2006 Journal of communications and networks Vol.8 No.4
In this work, we propose an analytic framework for dimensioning the link capacity of broadband access networks which provide universal broadband access services to a diverse kind of customers such as patient and impatient customers. The proposed framework takes into account the flow-level quality of service (QoS) of a connection as well as the packet-level QoS, via which a simple and systematic provisioning and operation of the network are provided. To that purpose, we first discuss the necessity of flow-aware network dimensioning by reviewing the networking technologies of the current and future access network. Next, we propose an analytic model for dimensioning the link capacity for an access node of broadband convergence networks which takes into account both the flow and packet level QoS requirements. By carrying out extensive numerical experiment for the proposed model assuming typical parameters that represent real network environment, the validity of the proposed method is assessed.
Power tail asymptotic results of a discrete time queue with long range dependent input
황강욱,Khosrow Sohraby 대한수학회 2003 대한수학회지 Vol.40 No.1
In this paper, we consider a discrete time queueing systemfed by a superposition of an ON and OFF source with heavy tail ON periods andgeometric OFF periods and a D-BMAP (Discrete Batch Markovian Arrival Process).We study the tail behavior of the queue length distribution andboth infinite and finite buffer systems are considered. In the infinitebuffer case, we show that the asymptotic tail behavior of the queue length of thesystem is equivalent to that of the same queueing system with the D-BMAP being replaced bya batch renewal process.In the finite buffer case (of buffer size K), we deriveupper and lower bounds of the asymptoticbehavior of the loss probability as K rightarrow infty.
POWER TAIL ASYMPTOTIC RESULTS OF A DISCRETE TIME QUEUE WITH LONG RANGE DEPENDENT INPUT
Hwang, Gang-Uk,Sohraby, Khosrow Korean Mathematical Society 2003 대한수학회지 Vol.40 No.1
In this paper, we consider a discrete time queueing system fed by a superposition of an ON and OFF source with heavy tail ON periods and geometric OFF periods and a D-BMAP (Discrete Batch Markovian Arrival Process). We study the tail behavior of the queue length distribution and both infinite and finite buffer systems are considered. In the infinite buffer case, we show that the asymptotic tail behavior of the queue length of the system is equivalent to that of the same queueing system with the D-BMAP being replaced by a batch renewal process. In the finite buffer case (of buffer size K), we derive upper and lower bounds of the asymptotic behavior of the loss probability as $K\;\longrightarrow\;\infty$.
Delay Analysis of Orderly Reattempts in Retrial Queueing System with Phase Type Retrial Time
Kumar, M. S.,Sohraby, K.,Kiseon Kim IEEE 2013 IEEE COMMUNICATIONS LETTERS Vol.17 No.5
<P>Retrial queueing systems play a major role in many communication systems. The delay analysis of such systems poses an interesting problem in communication engineering. This has motivated us to analyze the waiting time distribution of a multi-server retrial queueing system with phase type retrial time, impatience and Bernoulli abandonments. The impact of retrial time on waiting time and other system characteristics is analyzed by determining the waiting time distribution. Numerical examples are presented to reveal the impact of the parameters.</P>
Sohrabi, Nasrin,Rasouli, Nahid,Kamkar, Mehdi Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.8
In the present study, at first, azo Schiff base ligand of (N,N'-bis(5-phenylazosalicylaldehyde)-ethylenediamine) ($H_2L$) has been synthesized by condensation reaction of 5-phenylazosalicylaldehyde and ethylenediamine in 2:1 molar ratio, respectively. Then, its cobalt complex (CoL) was synthesized by reaction of $Co(OAc)_2{\cdot}4H_2O$ with ligand ($H_2L$) in 1:1 molar ratio in ethanol solvent. This ligand and its cobalt complex containing azo functional groups were characterized using elemental analysis, $^1H$-NMR, UV-vis and IR spectroscopies. Subsequently, the interaction between native calf thymus deoxyribonucleic acid (ct-DNA) and CoL complex was investigated in 10 mM Tris/HCl buffer solution, pH = 7 using UV-vis absorption, thermal denaturation technique and viscosity measurements. From spectrophotometric titration experiments, the binding constant of CoL complex with ct-DNA was found to be $(2.4{\pm}0.2){\times}10^4M^{-1}$. The thermodynamic parameters were calculated by van't Hoff equation.The enthalpy and entropy changes were $5753.94{\pm}172.66kcal/mol$ and $43.93{\pm}1.18cal/mol{\cdot}K$ at $25^{\circ}C$, respectively. Thermal denaturation experiments represent the increasing of melting temperature of ct-DNA (about $0.93^{\circ}C$) due to binding of CoL complex. The results indicate that the process is entropy-driven and suggest that hydrophobic interactions are the main driving force for the complex formation.
The tissue expression of MCT3, MCT8, and MCT9 genes in women with breast cancer
Sohrabi Ehsan,Moslemi Masoumeh,Rezaie Ehsan,Nafissi Nahid,Khaledi Mansoor,Afkhami Hamed,Fathi Javad,Zekri Ali 한국유전학회 2021 Genes & Genomics Vol.43 No.9
Background Breast cancer (BC) is a common malignancy with a high mortality rate. Malignant cell transformation is associated with metabolic changes. One group of proteins that are afected is the monocarboxylate transporters (MCTs-SLC16A). The MCTs comprise 14 members, and they play an important role in the growth, proliferation, and metabolism of cancer cells by transporting monocarboxylates such as lactate, pyruvate and thyroid hormones. Objective We aimed to evaluate the expression of MCT3 (SLC16A8), MCT8 (SLC16A2) and MCT9 (SLC16A9) genes in breast cancer samples, comparing to normal adjacent tissues. Methods Forty paired breast cancer tumor samples, the adjacent non-tumor and fve healthy tissues were collected. Three cancer cell lines (MCF-7, MDA-MB-231, and SKBR3) were also analyzed. The expression of SLC16A8, SLC16A2 and SLC16A9 were assessed using quantitative real-time PCR. The relationship between gene expression with the pathological features of the tumors, and the hormone receptors status of the patient’s tumors were also analyzed. Results There was a signifcantly lower expression of the MCT3 gene in tumor samples compared to adjacent normal tissue and healthy samples (p value<0.05). There was a signifcant diference in the expression of all three candidate genes between the BC tissues and normal tissues, and for the, tissues with diferent hormone receptor status and the molecular subtypes. Altered MCT8 and MCT9 gene expression was associated with a reduced survival Conclusion MCT3 expression is signifcantly downregulated in breast cancer tissue. MCT3 may represent a novel therapeutic target in breast cancer patients, or in some hormone receptor subgroups.
Sohrabi, Amir,Mirab-Samiee, Siamak,Modarressi, Mohammad Hossein,Izadimood, Narge,Azadmanesh, Kayhan,Rahnamaye-Farzami, Marjan Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Background: HPV related cervical cancer as one of the most common women cancers in developing countries. Regarding accessibility of commercial vaccines, any long or short term modality for integrating preventive immunization against HPV in a national program needs comprehensive information about HPV prevalence and its genotypes. The important role of selecting most accurate diagnostic technologies for obtaining relevant data is underlined by different assays proposed in the literature. The main objective of the present study was to introduce an in-house HPV typing assay using multiplex real time PCR with reliable results and affordable cost for molecular epidemiology surveys and diagnosis. MATERIALS AND METHODS: 112 samples of formalin fixed paraffin embedded tissues and liquid based cytology specimens from patients with known different grades of cervical dysplasia and invasive cancer, were examined by this method and the result were verified by WHO HPV LabNet proficiency program in 2013. RESULTS: HPV was detected in 105 (93.7%) out of 112 samples. The dominant types were HPV 18 (61.6%) and HPV 16 (42.9%). Among the mixed genotypes, HPV 16 and 18 in combination were seen in 12.4% of specimens. CONCLUSIONS: According to acceptable performance, easy access to primers, probes and other consumables, affordable cost per test, this method can be used as a diagnostic assay in molecular laboratories and for further planning of cervical carcinoma prevention programs.