Examination of Genetic Relationships of Silkworm Stocks in Korea by Additive Isozyme Analysis

Sohn, Bong-Hee,Kim, Hyun-Su,Kang, Pil-Don,Lee, Sang-Uk,Seong, Su-Il Korean Society of Sericultural Science 2002 International Journal of Industrial Entomology Vol.5 No.2

Previously, genetic relationships among 321 silkworm races preserved in the Department of Sericulture and Entomology, NIAST, RDA were studied using six isozymes comprising 20 loci. As a part of additional studies, three additional isozymes with 7 loci [phos-phoglucomutase (PGM), glucose phosphate isomerase (GPI), malete dehydrogenase (MDH)] from hemolymphs, midgets, and eggs were employed to reevaluate the previous dendrogram (UPGMA method). Although the current study supported the recognition of the previously identified major groups, some minor changes were apparent among the selected 47 forms. The current study showed that the polymorphic loci of GPI from eggs and MDH from hemolymph appear to be responsible characters for generating a new major group in the genetic relationship. Interpreting the data with current additive isozymes may represent more robust genetic relatioships among 321 silkworm races preserved in Korea, until further evidence is available.

Examination of Genetic Relationships of Silkworm Stocks in Korea by Additive Isozyme Analysis

( Bong Hee Sohn ),( Hyun Su Kim ),( Pil Don Kang ),( Sang Uk Lee ),( Su Il Seong ) 한국잠사학회 2002 International Journal of Industrial Entomology Vol.5 No.2

소아기 양성 외전신경마비 1례

손수예(Su Ye Sohn) · 신정희(Jeong Hee Shin) · 이장훈(Jang Hoon Lee) · 은소희(So-Hee Eun) · 은백린(Baik-Lin Eun) 대한소아신경학회 2010 대한소아신경학회지 Vol.18 No.1

저자들은 복시와 두통을 호소하고 편측 눈의 바깥쪽 회전이 완전히 제한된 소아에서 편측 외전신경마비 이외의 신경학적 검사상 정상 소견을 보이고,정상 뇌 MRI 소견 및 정상 뇌압, 그리고 미생물학검사에서 정상으로 특발성 외전신경마비로 진단하였고, 특별한 치료 없이 10일 내에 회복된 양성 경과를 보인 증례를 경험하여 보고하는 바이다. Benign abducens nerve palsy is rare in children. Identifiable causes of abducens nerve palsy include neoplasm, elevated intracranial pressure, infection and trauma. Isolated abducens nerve palsy with unknown etiology is classified as benign or idiopathic. The diagnosis is made by excluding underlying pathologies. Prognosis is favorable. Most patients have been found to recover spontaneously within 6 months. Recurrent palsy is observed in some patients and is more pronounced in younger girls with left-sided palsy. Even the recurrent cases, however, are still benign. We report a case of benign abducens nerve palsy presenting diplopia and headache with normal results from MRIs and microbiologic studies. The patient underwent rapid, spontaneous recovery.

고시 수재 의약품의 용출규격 설정 - 구연산니카메테이트 정, 노르플록사신 캡슐

김희연(Hee Yun Kim),최선희(Seon Hee Choi),방수진(Su Jin Bang),한경진(Kyung Jin Han),최승희(Sung Hee Choi),백지윤(Ji Yun Baek),김동섭(Dong Sup Kim),김영옥(Young Ok Kim),손경희(Kyung Hee Sohn),송영미(Young Me Song),사홍기(Hong Kee Sah) 大韓藥學會 2010 약학회지 Vol.54 No.5

Despite the fact that the dissolution test can serve as an effective tool for drug quality control and prediction of in vivo drug performance, there are a number of drugs with no established dissolution specifications because they were developed quite a long time ago. Under this circumstances, KFDA started the new project that establishes dissolution method and specifications for drugs with no dissolution specifications listed in the Korea Pharmaceutical Codex (KPC). This project aims for promoting the appropriate management of oral solid dosage forms. Seoul regional KFDA selected 2 items, Nicametate citrate tablet and Norfloxacin capsule, for establishing dissolution specifications. We went through the following procedures to develop the dissolution method and specifications: (1) Validation of dissolution test equipment, (2) Purchase of test drugs, (3) Preliminary test with one of the test products (1 lot), (4) Validation of analysis methods (3 lots), (5) Final tests and cross tests among other laboratory to establish dissolution specifications, (6) Additional test with the other test drugs. The outcome of this study will be reflected in revision of the KPC. It is believed that the quality control and evaluation of oral solid dosage forms listed in KPC will be advanced with the revision which adds additional dissolution test and specifications for the drugs with no established dissolution specifications.

일부 한국여대생의 로마진단기준에 의한 변비 실태조사 및 변비에 영향을 미치는 생활요인

정수진(Jung Su-Jin),채수완(Chae Soo-Wan),손희숙(Sohn Hee-Sook),김숙배(Kim Sook-Bae),노정옥(Rho Jeong-Ok),백상호(Baik Sang-Ho),강명희(Kang Myung-Hee),김건희(Kim Gun-Hee),김미현(Kim Mi-Hyun),김현숙(Kim Hyun-Sook),박은주(Park Eun-Ju),허영 韓國營養學會 2011 Journal of Nutrition and Health Vol.44 No.5

본 연구의 목적은 한국 일부 여대생 978명 대상으로 로마진단기준에 의한 변비 실태를 조사하고 변비증상을 가진 자와 정상배변 습관을 가진자들의 생활습관 배변상태 월경불편감 의생활 주거생활 식습관 및 식이섭취실태 등을 조사하여 변비와 관련성을 살펴보고 이를 영양교육 자료의 기초를 삼고자 실시하였다. 조사대상자는 인구비례에 근거한 전국 5개지역 소재 (서울/경기 경상 충청 전라 강원지역) 4년제 대학에 재학 중인 여대생 978명을 대상으로 2008년 5월부터 6월까지 조사를 실시하였다. 1) 조사대상자의 평균연령은 21.6세로 로마기준 II에 의한 변비실태 조사는 정상배변군과 변비군 각각 714명 (73.0%)과 264명 (27.0%)로 나타나 변비유병률은 27.0%로 나타났다. 2) 변비군에서 체중 (p < 0.05)과 체질량지수 (p < 0.05)는 정상배변군보다 더 높게 나타났고 비만도가 높을수록 변비발생 (p < 0.01)과 배변장애요인수 (p < 0.01)가 높았다. 3) 변비군의 경우 기능성대장질환 (p < 0.001)과 과민성대장질환 (p < 0.001) 치질 (p < 0.01)발생률과 대변모양이 비정상적 (p < 0.05)비율이 정상배변군보다 더 높게 나타나 배변상태와 변비여부와 관련성이 있는 것으로 나타났고 속쓰림증과 상복부 통증증상은 정상배변군에서 변비군보다 더 높게 나타났다 (p < 0.001). 4) 배변상태에 이상이 있고 변비가 있을 때 월경불편감을 느끼는 정도가 더 크게 나타났다. 5) 의류 (속옷류) 착용 시 인체에 나타나는 불편한 증상은 정상배변군보다 변비군에서 유의적으로 더 높았고 의류착용시 편안함이 높을수록 변비 (p < 0.01) 배변장애요인수 (p < 0.01) 기능성대장질환 (p < 0.01) 과민성대장질환 (p < 0.01) 및 월경불편감 (p < 0.01)은 유의적으로 낮았다. 6) 조사대상자의 평상시 식사의 규칙성 조사결과 변비군에서 아침식사가 불규칙적인 경우는 30.3% (p < 0.05) 점심식사와 저녁식사의 불규칙적인 경우는 각각 33.3% (p < 0.05)와 30.8% (p < 0.05)로 나타나 정상배변군보다 더 높게 나타났다. 또한 규칙적인 식사를 할수록 변비증세 (p < 0.01) 배변장애요인수 (p < 0.01) 기능성대장질환 (p < 0.01) 월경불편감 (p < 0.01) 음주률 (p < 0.01) 및 외식률 (p < 0.05)이 낮았다. 7) 식품군다양성점수 (DDS)는 정상배변군에서 4.22점인 반면 변비군에서는 4.12점보다 더 높게 나타나 (p < 0.05) 변비군의 경우 식사의 다양성이 낮았다. 8) 조사대상자의 주생활 요인 인자와 변비여부와의 관련성은 나타나지 않았다. 9) 변비상태와 건강관련 항목과의 관련성을 조사결과 변비가 있을수록 배변장애요인수 (p < 0.01),기능성대장질환 (p < 0.01) 과민성대장증후군 (p < 0.01) 및 월경불편감(p < 0.01)이 높은 것으로 나타났다. 본 연구결과 여대생들의 변비 증세를 감소시키기 위해서는 식생활습관의 정정과 함께 규칙적인 하루 3끼 식습관유지가 중요하고 식품 선택 시 다양하게 골고루 규칙적으로 섭취하는 것이 필요하다. 의류 착용 시 편안한 옷차림을 유지하고 속옷착용 시에도 편안하고 쾌적함을 유지를 통해 신체증후에 나타는 증상을 최소화하는 것이 변비 개선에 중요할 것으로 사료된다. 추후 가임기 성인여성 변비 예방을 위한 올바른 생활습관을 유지 및 개선 할 수 있는 실생활 교육지침과 기초자료 제공이 필요하다. This study investigated the actual status of constipation. In total 978 female students in Korea participated. We identified the relationship among constipation and life style clothing patterns housing patterns dietary habits and dietary intake in a constipation symptom group and a normal group. The actual constipation rate based on the Rome II criteria was 27.0% (n = 264). Body weight (p < 0.05) and body mass index (p < 0.05) in the constipation group were significantly higher than those in the normal group. The incidence of functional bowel disease and irritable bowel syndrome in the constipation group were significantly higher than those in the normal group. The discomfort of wearing underwear was significantly higher in the constipation group than that in the normal group. The constipation group revealed a significantly higher rate of irregular dietary habits than those in the normal group. The dietary diversity score of the normal group was 4.22 (p < 0.05) which was significantly higher than that of constipation group (4.12). No significant difference in life style factors was observed. It is necessary for university female students to correct their dietary habits maintain food intake of three times per day and select diverse foods. Furthermore it is necessary for university female students to wear comfortable clothing to lessen symptoms and improve constipation rates.

The study on the breast types and characteristics of Chinese female adults. (Ver. 1) -Focused on the female college students in Shanghai-

( Hee Soon Sohn ),( Su Joung Cha ) 한국패션비즈니스학회 2009 패션 비즈니스 Vol.13 No.3

The metabolic syndrome and body composition in childhood cancer survivors

Sohn, Young-Bae,Kim, Su-Jin,Park, Sung-Won,Kim, Se-Hwa,Cho, Sung-Yoon,Lee, Soo-Hyun,Yoo, Keon-Hee,Sung, Ki-Woong,Chung, Jae-Hoon,Koo, Hong-Hoe,Jin, Dong-Kyu The Korean Pediatric Society 2011 Clinical and Experimental Pediatrics (CEP) Vol.54 No.6

Purpose: Long-term survivors of childhood cancer appear to have an increased risk for the metabolic syndrome, subsequent type 2 diabetes and cardiovascular disease in adulthood compared to healthy children. The purpose of this study was to investigate the frequency of the metabolic syndrome and associated factors in childhood cancer survivors at a single center in Korea. Methods: We performed a retrospective review of medical records of 98 childhood cancer survivors who were diagnosed and completed anticancer treatment at Samsung Medical Center, Seoul, Korea between Jan. 1996 and Dec. 2007. Parameters of metabolic syndrome were evaluated between Jan. 2008 and Dec. 2009. Clinical and biochemical findings including body fat percentage were analyzed. Results: A total of 19 (19.4%) patients had the metabolic syndrome. The median body fat percentage was 31.5%. The body mass index and waist circumference were positively correlated with the cranial irradiation dose (r=0.38, P<0.001 and r=0.44, P<0.00, respectively). Sixty-one (62.2%) patients had at least one abnormal lipid value. The triglyceride showed significant positive correlation with the body fat percentage (r=0.26, P=0.03). The high density lipoprotein cholesterol showed significant negative correlation with the percent body fat (r=- 0.26, P=0.03). Conclusion: Childhood cancer survivors should have thorough metabolic evaluation including measurement of body fat percentage even if they are not obese. A better understanding of the determinants of the metabolic syndrome during adolescence might provide preventive interventions for improving health outcomes in adulthood.

Callus formation is associated with hyperproliferation, incomplete differentiation of keratinocytes, and increased expression of adhesion molecules

Su Hee Kim,Sooil Kim,Hye In Choi,Young Jin Choi,Young Sook Lee,Kyung Cheol Sohn,Young Lee,Chang Deok Kim,Tae Jin Yoon,Jeung Hoon Lee,Young Ho Lee 대한체질인류학회 2010 대한체질인류학회 학술대회 연제 초록 Vol.53 No.-

Comparison of brassiere sales patterns in Korea and China

( Su Joung Cha ),( Hee Soon Sohn ) 한국패션비즈니스학회 2008 패션 비즈니스 Vol.12 No.6

A Study on the Actual Conditions of Brassiere Wearing for Girl Students

( Hee Soon Sohn ),( Su Joung Cha ) 한국패션비즈니스학회 2005 패션 비즈니스 Vol.9 No.6

The purpose of this study is to help develop high quality brassieres with functionality and comfort, fitting adolescents` physical features during their growth period. This study conducts a comparative analysis of juvenile brassiere and adult brassiere to identify the problems of brassieres in the market. The raw data for this study was processed by SPSS 10.1. The results of this study are summarized as follows: 1. The results of this survey show that the girls` satisfaction of their breasts has correlations between breast protrusion degree and volume. The girls think that if they have protrusive breasts their breast volume is big, and their breast satisfaction level shows high. 2. The results show that the objective of brassiere wearing is to prevent breasts sag and rupture, make good breast shape, balance their entire body shape, and make beautiful outer garment line. Brassiere functions are to prevent jiggle of breasts, make a good body line, and cover the nipples. For the grader school students, they are wearing brassiere to make a good balanced body and as their breasts developed, they are wearing brassiere for beautiful body shape not just to cover up their breasts. 3. In regard to brassiere cup size recognition, as students have higher grade at school, they have better recognition abouxt their cup size. As they are better aware of their cup size, they have better satisfaction with their cup size. Therefore, choosing the right size of brassiere for their bust is very important. 4. Girl students` brassiere preference shows that 317 students (56.9%) prefer white for brassiere colors, following pink and flesh color. Their most preferred brassiere material is cotton (354 people, 63.6%) because cotton is not sensitive even for weak skin. For brassiere style, 273 students (49%) prefer round style, following spots and mold. Their most preferred brassiere style is stake. In addition, brassiere should not press their breasts because their breasts are developing during puberty period.