Clinical Outcome in Male Patients With Detrusor Overactivity With Impaired Contractility

Shuo Liu,Lewis Chan,Vincent Tse 대한배뇨장애요실금학회 2014 International Neurourology Journal Vol.18 No.3

Purpose: To review the clinical outcomes of patients with voiding dysfunction who have detrusor overactivity with impaired contractility (DOIC) diagnosed with urodynamic studies. Methods: Urodynamic reports from 2005 to 2009 were reviewed, and 54 male patients had findings consistent with DOIC. Patients with acontractile or neuropathic bladders were excluded. Clinical outcomes were obtained from patient records. Results: Of 54 men, 8 presented with voiding symptoms, 17 had storage symptoms, and 29 had mixed symptoms. Twenty-two had a previous transurethral resection of the prostate. The median follow-up was 12 months. Four patients received no intervention. Two patients were taught intermittent self-catheterization. Five patients underwent surgery to reduce outlet resistance and all reported improvement. Forty-three patients were started on pharmacotherapy; symptomatic improvement was reported by 9 of 16 patients commenced on anticholinergics alone, 6 of 16 on alpha-blockers alone, and 4 of 5 treated with a combination of alpha-blockers and anticholinergics. Eleven patients experienced no difference on pharmacotherapy and 2 reported deterioration. One patient developed acute urinary retention (18 months after commencing treatment with alpha-blockers). No patient had urosepsis. Conclusions: Anticholinergics and alpha-blockers appear to be safe in patients with DOIC. The risk of urinary retention and sepsis is low. The majority of patients report symptomatic benefit from either drugs or surgical treatment.

Effect of Run Ze Tonic in Mice with Kidney-Yin Deficiency

Shuo Liu,Si-yao Ma,Wen-yi Zhu,Jia Liang,Hong Meng 한국피부과학연구원 2021 아시안뷰티화장품학술지 Vol.19 No.1

목적: 본 연구는 Run Ze Tonic의 신장-음 결핍 마우스의 갑상선 호르몬, 부신 기능, 성 호르몬 및 주기적 뉴클레오티드에 미치는 영향을 관찰하고자 한다. 방법: ICR 마우스를 정상 대조군, 모델 그룹, Run Ze Tonic 고용량 그룹, 중간 용량 그룹 및 저용량 그룹으로 분류하였으며, 매 그룹은 20마리씩 구성하였다. 신장-음 결핍 마우스 모델은 연속 10 일 동안 1 일 1 회 레보 티록신 나트륨을 위내 직접 투여에 의해 확립되었다. 각 그룹의 마우스의 일반특징 및 체중을 관찰하고 장기지수를 측정하였다. 그리고 ELISA 방법으로 테트라 요오 도티 로닌 (T4), 트리 요오 도티 로닌 (T3), 갑상선 호르몬 (TSH), 코르티코 트로 핀 방출 호르몬 (CRH), 부 신피질 자극 호르몬 (ACTH), 코르티 코스 테론 (CORT), 테스토스테론 (T), 에스트라 디올 (E2), 고리 형 아데노신 모노 포스페이트 (cAMP) , 사 이 클릭 구아노 신 모노 포스페이트 (cGMP)를 측정하였다. 결과: Run Ze Tonic 고용량군은 신장-음결핍 마우스의 일반적인 신체 징후를 개선하고, 체중을 증가시키고(p<0.05), TSH 함량을 증가시킨다(p<0.01). 고용량 군에서 T3 및 T4 수치가 유의하게 감소하 였으며(p<0.01), ACTH 수준도 유의하게 감소하였다(p<0.05). 신장 음 결핍 암컷 마우스는 고용량 군에서 성 호르몬 E2 및 E2/T 비 율이 유의하게 감소(p<0.01)하였다. 신장 음이 결핍 된 수컷 마우스의 경우 고용량 군에서 성 호르몬 T함량이 유의하게 증가되었다 (p<0.05). 그리고 고용량 군에서 고리 형 뉴클레오티드 시스템의 cAMP 수치가 감소하였다(p<0.01). 결론: Run Ze Tonic은 내분비 계에서 호르몬 수치 장애, 부신 피질 기능 및 에너지 대사 균형을 조절하여 음양을 키우고 신장을 강화하는 역할을 할 수 있다고 사료된다. Purpose: To observe the effects of Run Ze Tonic on thyroid hormone, adrenal function, sex hormones and cyclic nucleotide of mice with kidney-yin deficiency. Methods: ICR mice were randomly grouped into normal control group, model group, Run Ze Tonic high dose group, the middle dose group and low dose group, male and female in half. The kidney-yin deficiency mice models were established by intragastric administration of levothyroxine sodium before intragastric administration of corresponding drugs once a day for 10 consecutive days. One day after the last administration, the effects were observed by measuring weight. And tetraiodothyronine (T4), triiodothyronine (T3), thyrotropin (TSH), corticotropin releasing hormone (CRH), adrenocorticotropic hormone (ACTH), corticosterone (CORT), testosterone (T), estradiol (E2), cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP) were tested by ELISA method. Results: Compared with the model group, the body weight, TSH level increased significantly (p <0.01, p<0.05), and T3, T4, ACTH level decreased significantly in high dose group (p <0.01, p <0.05). The E2 level in female decreased significantly in high dose group (p <0.01), the same as the ratio of E2/T (p <0.01). The T level in male increased significantly in high dose group (p <0.01), the same as the ratio of E2/T (p <0.01). And cAMP level decreased in the high dose group(p <0.05). Conclusion: Run Ze Tonic may play the role of nourishing yin and strengthening kidney by adjusting hormone level disorder, adrenal cortex function and balancing energy metabolism in endocrine system.

The Effect of On-line Product Presentation : A Comparative Study between 3D and General Product Presentation

Shuo liu 한국유통과학회 2017 The Journal of Industrial Distribution & Business( Vol.8 No.5

Purpose – This research aims to examine the effects of 3D online products presentation by comparing it with general presentation. Research design, data, and methodology – To rigorously investigate the differences of effects between 3D presentation and general presentation, this study examines the differences of the two presentations in vividness, informedness, entertainment, product trust, and purchase intention. This research designed two different forms of online product presentations, 3D and general presentation for an experiment. Results – The research findings indicate that 1) the vividness of online product presentation has a positive impact on the informedness and entertainment. While both vividness and informedness product presentation have a positive impact on product trust, the entertainment of online product presentation has no significant impact. 2) Vividness, informedness, entertainment, product trust, and purchasing intention showed significant differences between 3D and general product presentations. 3) Overall, 3D product presentation showed a stronger impact on purchasing intention than the general product presentation. Conclusions – This research expands the area of business presentation by comparing the differences of 3D and general presentation methods. This study made a great contribution to theory development, and also to guidelines for practice. These insights could be used by organizations in developing realistic environments for business presentations.

Dual 코일 하이브리드 제습 냉방 시스템 제안 및 성능 분석

유석(Shuo Liu),설염(Yan Xue),장휴산(Hyu San Jang),이태하(Tae Ha Leigh),정창호(Chang Ho Jeong),여명석(Myoung Souk Yeo) 대한설비공학회 2021 대한설비공학회 학술발표대회논문집 Vol.2021 No.6

Currently, the design and development of air conditioning systems increasingly requires consideration of indoor comfort, which makes the control of indoor humidity particularly important. Considering the miniaturization and complexity of the system structure, a heat pump assisted hybrid desiccant cooling system (HPDC system) using condenser waste heat to regenerate the desiccant was proposed in the previous study. Based on the problem of uncontrollable outlet temperature of this system, this paper has proposed an improved dual coil HPDC system and the corresponding system control logic and performed the thermal energy analysis by EnergyPlus software. The results show that the proposed system is able to maintain both the design indoor temperature and humidity. With the control logic, the increase in the number of cooling coil did not increase the cooling thermal energy consumption of the system, on the contrary, it was reduced by 2.1% compared to the previous system. But the design capacity of the second cooling coil should be larger than that of the previous system.

재열 시스템과 하이브리드 제습 냉방 시스템의 특성 비교 분석

유석(Shuo Liu),정창호(Chang Ho Jeong),여명석(Yeo Myoung Souk) 대한설비공학회 2020 대한설비공학회 학술발표대회논문집 Vol.2020 No.6

This study has compared the PTAC w/reheat system and the heat-pump assisted hybrid desiccant cooling (HPDC) system. EnergyPlus was applied to simulate the indoor thermal comfort and evaluate the system performance and dehumidification performance of HPDC system. As a result, compared with the PTAC w/reheat system, energy consumption of the HPDC system can be significantly reduced, and no additional heat source is needed to regenerate the desiccant wheel. The indoor temperature and humidity can be controlled within comfort range. There is the situation that indoor relative humidity exceeds the design relative humidity during the HPDC system operation, which accounts for 0.8% of the system operation time and only occurs when the outdoor temperature is low. The system performance of HPDC system improves with the increase of outdoor temperature and humidity, but the performance trend of the PTAC w/reheat system is opposite. The dehumidification performance of the HPDC system decreases with the increase of dehumidification load.

A Study of Storm Surge Disasters Based on Extreme Value Distribution Theory

Yang, Shuo,Liu, Xin,Liu, Qiang,Guan, Li,Lee, Jae Myung,Jung, Kwang Hyo Coastal Education and Research Foundation 2017 Journal of coastal research Vol.33 No.6

Gut-derived lipopolysaccharide promotes alcoholic hepatosteatosis and subsequent hepatocellular carcinoma by stimulating neutrophil extracellular traps through toll-like receptor 4

Yang Liu,Xin Zhang,Shuo Chen,Jiazhong Wang,Shuo Yu,Yiming Li,Meng Xu,Harouna Aboubacar,Junhui Li,Tao Shan,Jixin Wang,Gang Cao 대한간학회 2022 Clinical and Molecular Hepatology(대한간학회지) Vol.28 No.3

Background/Aims: Binge drinking leads to many disorders, including alcoholic hepatosteatosis, which is characterized by intrahepatic neutrophil infiltration and increases the risk of hepatocellular carcinoma (HCC). Molecular mechanisms may involve the migration of bacterial metabolites from the gut to the liver and the activation of neutrophil extracellular traps (NETs). Methods: Serum samples from both binge drinking and alcohol-avoiding patients were analyzed. Mouse models of chronic plus binge alcohol-induced hepatosteatosis and HCC models were used. Results: A marker of NETs formation, lipopolysaccharide (LPS), was significantly higher in alcoholic hepatosteatosis and HCC patients and mice than in controls. Intrahepatic inflammation markers and HCC-related cytokines were decreased in mice with reduced NET formation due to neutrophil elastase (NE) deletion, and liver-related symptoms of alcohol were also alleviated in NE knockout mice. Removal of intestinal bacteria with antibiotics led to decreases in markers of NETs formation and inflammatory cytokines upon chronic alcohol consumption, and development of alcoholic hepatosteatosis and HCC was also attenuated. These functions were restored upon supplementation with the bacterial product LPS. When mice lacking toll-like receptor 4 (TLR4) received chronic alcohol feeding, intrahepatic markers of NETs formation decreased, and hepatosteatosis and HCC were alleviated. Conclusions: Formation of NETs following LPS stimulation of TLR4 upon chronic alcohol use leads to increased alcoholic steatosis and subsequent HCC.

太极拳馆高质量发展的双元平衡路径

刘硕(Shuo Liu),李爱增(Aizeng Li),张帅帅(Shuaishuai Zhang) YIXIN 출판사 2023 Journal of Humanities and Social Sciences Vol.1 No.2

作为体育场馆的重要组成部分以及构建更高水平的全民健身公共服务体系重要推动力,太极拳馆应紧跟时代步伐,走向高质量发展的道路。本文在太极拳馆高质量发展的机会和困境分析之后,提出以双元平衡为理论基础的经济效益与社会效益双元平衡的发展路径。 As an important component of sports venues and an important driving force for building a higher-level public service system for national fitness, Tai Chi gymnasium should keep up with the pace of the times and move towards high-quality development. After analyzing the opportunities and difficulties of high-quality development of Tai Chi Gymnasium, this article proposes a development path based on the dual balance of economic and social benefits.

Status, Trend and Strategy on Municipal Wastewater Management in China

Wang Baozhen,Wang Lin,Liu Shuo,Wang Li,Wang Zheng 대전대학교 환경문제연구소 2007 환경문제연구소 논문집 Vol.11 No.-

Solidification of uranium mill tailings by MBS-MICP and environmental implications

Niu Qianjin,Li Chunguang,Liu Zhenzhong,Li Yongmei,Meng Shuo,He Xinqi,Liu Xinfeng,Wang Wenji,He Meijiao,Yang Xiaolei,Liu Qi,Liu Longcheng 한국원자력학회 2022 Nuclear Engineering and Technology Vol.54 No.10

Uranium mill tailing ponds (UMTPs) are risk source of debris flow and a critical source of environmental U and Rn pollution. The technology of microbial induced calcium carbonate precipitation (MICP) has been extensively studied on reinforcement of UMTs, while little attention has been paid to the effects of MICP on U & Rn release, especially when incorporation of metakaolin and bacillus subtilis (MBS). In this study, the reinforcement and U & Rn immobilization role of MBS -MICP solidification in different grouting cycle for uranium mill tailings (UMTs) was comprehensively investigated. The results showed that under the action of about 166.7 g/L metakaolin and ~50% bacillus subtilis, the solidification cycle of MICP was shortened by 50%, the solidified bodies became brittle, and the axial stress increased by up to 7.9%, and U immobilization rates and Rn exhalation rates decrease by 12.6% and 0.8%, respectively. Therefore, the incorporation of MBS can enhance the triaxial compressive strength and improve the immobilization capacity of U and Rn of the UMTs bodies solidified during MICP, due to the reduction of pore volume and surface area, the formation of more crystals general gypsum and gismondine, as well as the enhancing of coprecipitation and encapsulation capacity