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        Rehabilitation Nutrition and Exercise Therapy for Sarcopenia

        Kakehi Shingo,Wakabayashi Hidetaka,Inuma Hayato,Inose Tomomi,Shioya Moeka,Aoyama Yohei,Hara Taiki,Uchimura Kosuke,Tomita Kazusa,Okamoto Mizuki,Yoshida Masato,Yokota Shohei,Suzuki Hayato 대한남성과학회 2022 The World Journal of Men's Health Vol.40 No.1

        Sarcopenia is an age-related loss of skeletal muscle associated with adverse outcomes such as falls, fractures, disability, and increased mortality in older people and hospitalized patients. About half of older male nursing home residents have sarcopenia. The diagnostic criteria by the European Working Group on Sarcopenia in Older People (EWGSOP) and the Asian Working Group for Sarcopenia (AWGS) have led to increased interest in sarcopenia. Exercise and nutritional management are crucial for the prevention and treatment of sarcopenia. Nutritional therapy for sarcopenia that includes 20 g of whey protein and 800 IU of vitamin D twice a day improves lower limb strength. Exercise therapy for sarcopenia, such as resistance training and 6 months of home exercises, improves muscle strength and physical function. Combination therapy that includes both nutritional and exercise therapy improves gait speed and knee extension strength more than either exercise alone or nutrition therapy alone. Excessive bedrest and mismanagement of nutrition in medical facilities can lead to iatrogenic sarcopenia. Iatrogenic sarcopenia is sarcopenia caused by the activities of health care workers in health care facilities. Appropriate nutritional management and exercise programs through rehabilitation nutrition are important for prevention and treatment of iatrogenic sarcopenia. Nutritional and exercise therapy should be started very early after admission and adjusted to the level of inflammation and disease status. Repeated assessment, diagnosis, goal setting, interventions, and monitoring using the rehabilitation nutrition care process is important to maximize treatment effectiveness and improve patients’ functional recovery and quality of life.

      • Fabrication of Semi-Artificial Cellulose Fiber Production System Using Cellulose Spinning Machinery of Bacteria

        ( Go Takayama ),( Shingo Yokota ),( Tetsuo Kondo ) 한국목재공학회 2021 한국목재공학회 학술발표논문집 Vol.2021 No.1

        Nanocelluloses, which are produced by nano-downsizing processes of pulp fibers, have attracted much attention in recent years due to their excellent physical properties and specific surface characteristics. For material design using nanocelluloses, facile understanding of the relationship between structure and property is an essential issue. In contrast, as the 3D-stractural formation starting from biosynthesis of native nanocelluloses has been still complexed as a bottom-up mechanism, it prevents the control of their hierarchical structure in native systems including bacterial producing system. A model system of cellulose fiber spinning mechanism would contribute to the further understanding of the 3D-hierachical structure formation of nanocelluloses. Biosynthesis of native cellulose accompanied with polymerization and crystallization processes is well known to be achieved through synthetic enzyme complexes called Terminal Complexes (TCs). However, the following process including assembly of the nanofibrils secreted from cells has been still unclear, even though the combination of the biosynthesis and the following assembly process is of importance to establish the nano/micro fibrils of cellulose. Then, this unique process leads to the remarkable characteristics of native cellulose fibers. A cellulose-producing bacterium, Gluconacetobacter, has been extensively studied as a model-organism of the cellulose biosynthesis and there have been many studies on in vitro reconstruction of the cellulose synthesis activity. In this study, for the above goal, we first explored a method to extract intact TCs of Gluconacetobacter xylinus from the cell without outer cell walls, and then cellulose fiber spinning activity of the extracted TCs were examined to confirm the intact ability. Namely, bacteria (ATCC23769) were subjected to cell wall digestion treatment and then were burst by osmotic shock to obtain cell membrane fragments holding intact TCs. Finally, cellulose synthesis reaction was conducted using the burst cells.

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        Comparative Analysis of the WISC between Two ADHD Subgroups

        Yoichiro Kubo,Tetsufumi Kanazawa,Yasuo Kawabata,Koyuki Tanaka,Tatsushi Okayama,Miho Fujta,Atsushi Tsutsumi,Shingo Yokota,Hiroshi Yoneda 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.2

        ObjectiveaaThe prevalence of attention deficit/hyperactivity disorder (ADHD) in school-age children is 7.2%, and ADHD is divided into clinical subtypes. MethodsaaThe current study explored whether specific cognitive profiles as assessed using the Wechsler Intelligence Scale for Children (WISC)-IV could be obtained for each clinical ADHD subtype (ADHD-Inattentive type and ADHD-Combined type) and investigated the correlation between WISC scores and parental age at their children’s birth or birthweight. The enrolled sample comprised 12 ADHD- I and 15 ADHD-C subjects. ResultsaaAn impaired Processing Speed Index was found in ADHD-I. The age of the father at the child’s birth and birthweight positively correlated with the full scale intelligence quotient (FSIQ) score in the WISC assessment. ConclusionaaInattentiveness within the behaviors of the children with ADHD-I is partly due to the impaired processing speed, therefore effective support for ADHD will be conducted if educator decreases their speaking speed. Since biological basis of ADHD is still largely unknown, future studies using both psychological and biological methods will reveal the etiology of ADHD. These scientific assessments will provide information for more effective approaches in the care of children with ADHD.

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