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이승욱(SeungWook Lee),박영우(YongWoo Park),한양선(Yang Sun Han),장판식(Pahn-Shick Chang),이종미(Jong-Mee Lee),김영석(Young Suk Kim),이재환(JaeHwan Lee) 한국식품과학회 2009 한국식품과학회지 Vol.41 No.2
청육장은 볶은 대두를 이용하여 제조된 청국장에 해산물, 육류를 함께 가열한 반가 식품의 일종이다. 140과 220℃에서 각각 21.0과 6.0분 간 볶은 대두와 이를 이용한 청국장, 청육장의 총 아이소플라본을 HPLC로 분석하였다. 총 아이소플라본 함량(μmol/g)은 생 대두 대비 약 79-80, 56-65, 47-50%이었다. 볶음 공정으로 인해 malonyl-β-glucosides 함량은 유의적으로 감소한 반면 acetyl-β-glucosides와 β-glucosides의 함량은 유의적으로 증가하였다(p < 0.05). 청국장과 청육장의 주된 아이소플라본은 β-glucosides이었다. 생 대두와 볶은 대두에서는 succinyl-β-daidzin과 succinyl-β-genistin은 검출되지 않았고, 청국장과 청육장에서 succinyl-β-genistin의 peak area는 succinyl-β-daidzin 보다 더 높게 검출되었다. Cheongyukjang, a Banga food, is a heavy soy-soup prepared by boiling cheonggukjang, sea foods, and meats. Soybeans roasted at 140℃ for 21.0 min and 220℃ for 6.0 min, respectively, were used for cheonggukjang preparation. Distributions of isoflavones in raw soybeans, roasted soybeans, cheonggukjang, and cheongyukjang were analyzed by high performance liquid chromatography. The total isoflavones in roasted soybeans, cheonggukjang and cheongyukjang were about 79-80, 56-65, and 47-50% of those in raw soybeans, respectively. Roasting caused significant increases in acetyl derivatives and β-glucoside isoflavones, and significant decreases in malonyl derivatives (p < 0.05). The major isoflavones in cheonggukjang and cheongyukjang were β-glucosides. Succinyl-β-daidzin and succinyl-β-genistin, which are recognized as new metabolites of isoflavones, were not detected in raw and roasted soybeans. Peak areas of succinyl-β-genistin were higher than thse of succinyl-β-daidzin, in both cheongyukjang and cheonggukjang.
Development of an integrated breeding platform for data-driven crop improvement
Yeisoo Yu(Yeisoo Yu),SeungWook Lee(SeungWook Lee),Suhyeon Park(Suhyeon Park),Changyuel Lee(Changyuel Lee),Youngsil Kim(Youngsil Kim),Daegyu Kim(Daegyu Kim),Seok Jae Yun(Seok Jae Yun),Dae Kwan Kim(Da 한국육종학회 2023 한국육종학회 공동학술발표집 Vol.2023 No.-
Lee, Kyung-Min,Oh, Taek-Joo,Kim, So-Hyun,Kim, Hye-Youn,Chung, Hyunmi,Min, Daniel Seungwook,Auh, Joong-Hyuck,Lee, Hong Jin,Lee, Jaehwi,Choi, Hyung-Kyoon Korean Society of Food Science and Technology 2016 Food Science and Biotechnology Vol.25 No.4
In this study, comprehensive metabolic profiles of mulberry fruits (Morus alba Linnaeus) at various maturation stages were determined using GC-MS and HPLC. In total, 48 compounds, including 3 alcohols, 16 amino acids, 7 organic acids, 2 sugars, 4 phenolics, 2 terpenes, 3 vitamins, 9 fatty acids, and 2 cyanidins were identified in the mulberry samples. Levels of chlorogenic acid, cryptochlorogenic acid, neochlorogenic acid, ascorbic acid, and ${\delta}-tocopherol$, and total fatty acid content were significantly higher in the semi-matured mulberry fruits. Furthermore, levels of glycerol, citrate, fructose, glucose, 3-O-glucoside, and cyanidin-3-O-rutinoside were significantly higher at the fully matured stage than at the other stages. Twelve biosynthetic pathways were suggested as major pathways involved in mulberry fruit maturation. The information obtained in this study will provide a basis for future investigations toward quality control or metabolic engineering for development of mulberry fruits possessing commercially valuable characteristics.
A Guideline of Computer-based Training Design Considering HCI Principles and Usability Evaluation
Seungwook Lee,Jiyoung Kim,Wongi Hong,Joohyun Jung,Youngwon Choi,Byeongho Bak 대한인간공학회 2015 대한인간공학회 학술대회논문집 Vol.2015 No.10
Objective: The aim of this study is to establish a guidelines of CBT(Computer-Based Training) GUI design considering HCI(Human-Computer Interaction) principles and Usability evaluation components. Background: There are many studies on the GUI(Graphic User Interface) design guidelines such as mobile applications and website; however, lacked of consideration for a specialized field such as the military. Method : A three research was applied in the study. (1) Define HCI Principles, (2) Review of existing CBTs and Web-based training system, (3) Research of Usability evaluation criterion components Results: A guideline of CBT design was consisted of 8 design components, and develop for three screen(log-in/initial/learning) and 4 areas(title/menu/contents/script) in the integrated 12 Usability evaluation components. Conclusion: A guideline of CBT design can be applicable to develop CBT screen design in the integrated usability.
Hybrid Temperature Sensor Network for Area-Efficient On-Chip Thermal Map Sensing
Seungwook Paek,Wongyu Shin,Jaeyoung Lee,Hyo-Eun Kim,Jun-Seok Park,Lee-Sup Kim IEEE 2015 IEEE journal of solid-state circuits Vol.50 No.2
<P>Spatial thermal distribution of a chip is an essential information for dynamic thermal management. To get a rich thermal map, the sensor area is required to be reduced radically. However, squeezing the sensor size is about to face its physical limitation. In this background, we propose an area-efficient thermal sensing technique: hybrid temperature sensor network. The proposed sensor architecture fully exploits the spatial low-pass filtering effect of thermal systems, which implies that most of the thermal information resides in very low spatial frequency region. Our on-chip sensor network consists of a small number of accurate thermal sensors and a large number of tiny relative thermal sensors, responsible for low and high spatial frequency thermal information respectively. By combining these sensor readouts, a thermal map upsampler synthesizes a higher spatial resolution thermal map with a proposed guided upsampling algorithm.</P>
Lee, Hansol,Lee, Joonsung,Joe, Eunhae,Yang, Seungwook,Choi, Young-suk,Wang, Eunkyung,Song, Ho-Taek,Kim, Dong-Hyun Korean Society of Magnetic Resonance in Medicine 2015 Investigative Magnetic Resonance Imaging Vol.19 No.4
Purpose: For a single time-point hyperpolarized $^{13}C$ magnetic resonance spectroscopy imaging (MRSI) of animal models, scan-time window after injecting substrates is critical in terms of signal-to-noise ratio (SNR) of downstream metabolites. Pre-scans of time-resolved magnetic resonance spectroscopy (MRS) can be performed to determine the scan-time window. In this study, based on two-site exchange model, protocol-specific simulation approaches were developed for $^{13}C$ MRSI and the optimal scan-time window was determined to maximize the SNR of downstream metabolites. Materials and Methods: The arterial input function and conversion rate constant from injected substrates (pyruvate) to downstream metabolite (lactate) were precalibrated, based on pre-scans of time-resolved MRS. MRSI was simulated using two-site exchange model with considerations of scan parameters of MRSI. Optimal scan-time window for mapping lactate was chosen from simulated lactate intensity maps. The performance was validated by multiple in vivo experiments of BALB/C nude mice with MDA-MB-231 breast tumor cells. As a comparison, MRSI were performed with other scan-time windows simply chosen from the lactate signal intensities of pre-scan time-resolved MRS. Results: The optimal scan timing for our animal models was determined by simulation, and was found to be 15 s after injection of the pyruvate. Compared to the simple approach, we observed that the lactate peak signal to noise ratio (PSNR) was increased by 230%. Conclusion: Optimal scan timing to measure downstream metabolites using hyperpolarized $^{13}C$ MRSI can be determined by the proposed protocol-specific simulation approaches.