The Rare and Challenging Presentation of Gastric Cancer during Pregnancy: A Report of Three Cases

Pacheco, Sergio,Norero, Enrique,Canales, Claudio,Martinez, Jose Miguel,Herrera, Maria Elisa,Munoz, Carolina,Jarufe, Nicolas The Korean Gastric Cancer Association 2016 Journal of gastric cancer Vol.16 No.4

Pregnancy-associated gastric cancer is extremely rare. In many cases, it is diagnosed at an advanced stage because the symptoms during pregnancy are generally overlooked. We report three cases of gastric cancer during pregnancy with various outcomes. The first case included a patient with stage IV gastric cancer who received palliative chemotherapy. This patient had a preterm birth and died 7 months after diagnosis. The second case received neoadjuvant chemotherapy during pregnancy and a total gastrectomy was performed after delivery. She then received adjuvant chemoradiotherapy. This patient developed pulmonary metastasis and died of recurrence 41 months after surgery. In the third case, a distal subtotal gastrectomy was performed at week 14 of pregnancy, with no complications. The patient received adjuvant chemoradiotherapy. She is currently without recurrence 14 months after surgery. In patients with pregnancy-associated gastric cancer, treatment decisions are predominantly influenced by clinical stage and gestational age at diagnosis.

The Rare and Challenging Presentation of Gastric Cancer during Pregnancy: A Report of Three Cases

Sergio Pacheco,Enrique Norero,Claudio Canales,José Miguel Martínez,María Elisa Herrera,Carolina Muñoz,Nicolás Jarufe 대한위암학회 2016 Journal of gastric cancer Vol.16 No.4

Pregnancy-associated gastric cancer is extremely rare. In many cases, it is diagnosed at an advanced stage because the symptoms during pregnancy are generally overlooked. We report three cases of gastric cancer during pregnancy with various outcomes. The first case included a patient with stage IV gastric cancer who received palliative chemotherapy. This patient had a preterm birth and died 7 months after diagnosis. The second case received neoadjuvant chemotherapy during pregnancy and a total gastrectomy was performed after delivery. She then received adjuvant chemoradiotherapy. This patient developed pulmonary metastasis and died of recurrence 41 months after surgery. In the third case, a distal subtotal gastrectomy was performed at week 14 of pregnancy, with no complications. The patient received adjuvant chemoradiotherapy. She is currently without recurrence 14 months after surgery. In patients with pregnancy- associated gastric cancer, treatment decisions are predominantly influenced by clinical stage and gestational age at diagnosis.

Volatiles from Marina neglecta: Biocide effect on insect vectors of tropical diseases in Southern Mexico

Pacheco-Hernández Yesenia,Jonnathan Castro-Juárez Carlos,Alberto Ramírez-García Sergio,Cruz-Durán Ramiro,Lozoya-Gloria Edmundo,Villa-Ruano Nemesio 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.2

Preventive measures based in the control of insect vectors are considered as the best choice to decrease the incidence of insect-borne diseases. Herein we report on the volatile content of the leaf essential oils from Marina neglecta, a medicinal plant distributed in the tropical regions of southern Mexico. In order to investigate the chemical variation of the essential oils, a volatile screening was performed during the four seasons of the years 2016–2019. Simultaneously, their biological activity was tested on distinct life stages of Meccus pallidipennis, M. bassolsae, Aedes aegypti and A. albopictus. Essential oils were mainly constituted of β-pinene (>30%) β-car yophyllene (>25%) and germacrene D (>13%). Dorsal-abdomen application of essential oils on triatomines, revealed an efficient LC 50 for nymphs of the stages I to III (4 µg/insect), nymphs of the stages IV to V (5–6 µg/ insect), and adults (7–8 µg/insect). The LT 50 for the stages I to III was between 6 and 8 h, whereas that for the stages IV to V and adults oscillated between 12 and 16 h and 22 to 26 h, respectively. Fumigation experiments performed on nymph V, demonstrated that 300 µg L − 1 air produced 100% mortality after 72 h post-treatment. Among tested volatiles, β-pinene and β-caryophyllene produced a comparable mortality rate (p < 0.01) than that of essential oils in the stages assayed. Essential oils showed strong larvicidal (LC 50 , 24–36 µg mL − 1 ) and adul ticidal (35–48 µg mL − 1 ) activities in mosquito species with an LT 50 of 4.5 h and 25–35 min, respectively. The evaluation of β-pinene produced a significant mortality rate (p < 0.01) in larvae whereas germacrene D was the most effective volatile (p < 0.01) against adults of both mosquito species. According to our results, β-pinene was the most effective volatile against the four insect species evaluated and its effect was comparable to that of the essential oil.

Influence of hydrodynamic parameters in plate heat exchangers in ice slurry transport

Jiménez Pacheco Hugo Guillermo,Milon Guzmán Juan José,Miranda Ramos Lilia Mary,Delgado Sarmiento Pavel Kewin,Linares Flores Castro Antonio Erick,Leal Braga Sergio 대한설비공학회 2023 International Journal of Air-Conditioning and Refr Vol.31 No.1

Ice slurry is applied in different refrigeration and air conditioning systems, and among its main advantages is the ability to store latent heat and be pumpable as cold water. This fluid can be used for thermal storage instead of cold water or solid ice, since, at certain concentrations, it can be pumped through heat exchangers. For this technology to be widely used, the equipment must be designed considering the heat exchange characteristics. This study developed an experimental system to study the parameters that influence heat exchange, using ice slurry in a plate heat exchanger and water as a thermal load. Several situations with different flows and initial fractions of ice in ice slurry were analyzed. The input conditions of the thermal load were kept constant, the temperature, the pressure drop and the flow of the ice slurry in the heat exchanger were controlled, according to the Nusselt, Prandtl, and Reynolds coefficients. Results show that the global heat exchange coefficient increases with the increase of the initial ice fraction; the cooling capacity of the heat exchanger increases when ice slurry is used as a fluid. For flow rates greater than 0.16 kg/s and ice fractions above 11%, ice crystals are generated at the heat exchanger outlet, due to the ice slurry’s higher viscosity, at approximately 0.003 Pa at the outlet, since the pressure drop increases as the initial ice fraction increases. Results show ice slurry thermohydraulic behavior. Its use shows favorable characteristics in heat exchange. Ice slurry is applied in different refrigeration and air conditioning systems, and among its main advantages is the ability to store latent heat and be pumpable as cold water. This fluid can be used for thermal storage instead of cold water or solid ice, since, at certain concentrations, it can be pumped through heat exchangers. For this technology to be widely used, the equipment must be designed considering the heat exchange characteristics. This study developed an experimental system to study the parameters that influence heat exchange, using ice slurry in a plate heat exchanger and water as a thermal load. Several situations with different flows and initial fractions of ice in ice slurry were analyzed. The input conditions of the thermal load were kept constant, the temperature, the pressure drop and the flow of the ice slurry in the heat exchanger were controlled, according to the Nusselt , Prandtl , and Reynolds coefficients. Results show that the global heat exchange coefficient increases with the increase of the initial ice fraction; the cooling capacity of the heat exchanger increases when ice slurry is used as a fluid. For flow rates greater than 0.16 kg/s and ice fractions above 11%, ice crystals are generated at the heat exchanger outlet, due to the ice slurry’s higher viscosity, at approximately 0.003 Pa at the outlet, since the pressure drop increases as the initial ice fraction increases. Results show ice slurry thermohydraulic behavior. Its use shows favorable characteristics in heat exchange.