초내열 합금 Alloy718의 저주기 피로시험에서 반복연화 및 R=X (X=0,-1)효과

최병학,신수근,신정근,김선화,윤기봉,염종택,박노광 국립7개대학공동논문집간행위원회 2005 공업기술연구 Vol.5 No.-

The LCF properties for R=0 as tension-tension and R=-1 as tension-compression were examined in DA alloy718. While the hysteresis loops composed of ?ε_(t), ?ε_(p) and ?σ were figured with similaity in both of R=0 and R=-1, the loops of R=0 were continuely going down along the stress axis during cyclic fatigue progressing. It was caused by Bauschinger effect, which includes a tendancy for stress recovering as an amount of compression stress. The phenomena of cyclic softening in both of R=0 and R=1 seem to be caused by planar slip of dislocations, which was accompanied by shearing the γ'/γ" precipitates during the cyclic fatigue test.

급성 백혈병 환자에서 발생한 감염 양상의 분석(1986~1992)

박선양,오명돈,김양수,백경란,김병국,최강원,김성민 대한감염학회 1993 감염 Vol.25 No.3

Infection is a major complication and potentially life-threatening in patients with acute leukemia. The patients require prompt broad-spectrum antibiotics therapy when fever develops. One of the keys to successful patient management is the recognition of institutional trends of the spectrum of infections and infecting microorganisms. So we evaluated 138 patients with acute leukemia and blastic crisis of chronic myelogenous leukemia admitted to Seoul National University Hospital from July 1986 to June 1992. The results are following: 1) Total number of febrile episodes was 224 and 60% of them occurred after chemotherapy. 2) Microbiologically-defined infection, clinically-defined infection, and unexplained fever accounted for 28%, 45%, 27% of the febrile episodes respectively. 3) Fifty-eight percent of microbiologically-defined infections were caused by gram-negative bactria, and 36% were gram-positive bacteria. There was a tendency to a greater proportion of gram (+) organisms than that of the last study (p>0.1). Escherichia coli was the most common organism, and coagulase-negative staphylococci, Pseudomonas aeruginosa, Klebsiella pneumoniae were common in decreasing order. 4) Pneumonia was the most common type of infection, followed by skin and soft tissue infection, perianal infection, gingivitis and primary septicemia. 5) Seventy-two percent of total infections improved with therapy and this success rate was higher than that of the last study(p<0.001).

아동병동 간호사의 경력에 따른 아동 통증지식에 대한 연구

최선일,최명애 대한기초간호자연과학회 2005 Journal of korean biological nursing science Vol.7 No.1

Purpose : The purpose of this study was to identify pediatric nurses’s knowledge related to children's pain and pediatric nurses’ career including educational experience and to examine whether there is a difference of their knowledge according to their career. Method : Subjects of this study was 115 pediatric nurses of one university hospital who understood purpose of this study and accepted to participate in this study. Subjects responded questionnaire by self report. The data were gathered for 7 days during the period from October 20 to October 27, 2003. The pediatric nurses' knowledge and attitude survey regarding pain developed by Manworren(2001) was used to identify the knowledge related to children’s pain of pediatric nurses. Nurses’ career consisted of level of education, presently working ward, duration of experience at clinic, pediatric clinic and presently working ward and educational experience related to children's pain during undergraduate courses, ward orientation and continuing education. Educational experience regarding children’s pain was measured by whether they had education related to children’s pain during undergraduate courses, ward orientation and continuing education or not and their perception on the contents of education was measured by 5 point Likert type scale. SPSS Windows was used to analyze the data. Scores of the knowledge regarding children’s pain and career including educational experience of pediatric nurses were presented as mean and standard deviation. Mean percentage of correct answers responded by the subjects was presented under the category of introduction, assessment, pharmacological and nonpharmacological intervention for children’s pain. The difference of scores of the knowledge regarding children’s pain according to nurses’ career was analyzed using t-test, ANOVA and Tukey as a post hoc. Statistical significance was accepted at the level of p<.05. Result : Pediatric nurses had deficient knowledge related to children’s pain on the whole and did not trust pain complaint and underestimated the pain. They were short of concrete practical knowledge about pain assessment and pharmacological and nonpharmacological intervention for children’s pain. They were excessively concerned with side effect and addiction of analgesic drugs and had a negative view point on nonpharmacological pain intervention. About 50% of the subjects received education regarding children’s pain while their undergraduate courses. The number of nurses who received education regarding children’s pain while their undergraduate courses was found to be greater among the recently graduated nurses. In ward orientation and continuing education, only less than 10% of the nurses received education regarding children’s pain. Nurses perceived their experienced educational content deficient; experienced educational content consisted of pain introduction, assessment and pharmacological and nonpharmacological intervention for children’s pain while their undergraduate course, ward orientation and continuing education. There were no significant differences of the knowledge regarding children’s pain of pediatric nurses according to level of education, duration of experience at clinic, pediatric clinic and presently working ward. Scores of the knowledge regarding children’s pain of nurses at neonatal ward were significantly greater than those of nurses at pediatric intensive care unit. Scores of the knowledge regarding children’s pain of pediatric nurses who received education during their undergraduate course were significantly greater than those who did not receive it during their undergraduate courses. Also scores of the knowledge regarding children’s pain of pediatric nurses who received one kind of educational experience were significantly greater than those who had no educational experience. Conclusion : Pediatric nurses had deficient knowledge of children's pain and underestimated the pain of children. Also they were short of concrete practical knowledge on pain assessment and intervention for children’s pain.

자궁경부암 냉동조직에서 Polymerase Chain Reaction (PCR)을 이용한 인 유듀종바이러스 (HPV)의 출현과 임상적 특징과의 연관성에 관한 연구

권선호,남상륜,이증훈,노재랑,최준호 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.1

Infection with human papillomavirus(HPV) is considered to be the principal causal agent in the development of the uterine cervical cancer. To detect HPV types prevalent in carcinoma of the uterine cervix, a type-specific, sensitive polymerase chain reaction(PCR)-based assay for HPV types 16, 18, and 33 was applied to 40 cervical carcinomas(39 squamous cell carcinomas and 1 adenocarcinoma), 6 cases of cervical intraepithelial neoplasia(CIN), and 18 samples of cervicitis and histologically normal cervix. PCR was done using 2 sets of Ll primer of HPV-16 and 18, 1 set of E2/E1 primer of HPV-33, and 3 sets of E6 primer of HPV-16, 18, 33. The amplified product was analyzed directly on the basis of the size of the ethidium bromide-stained band visible after agarose gel electrophoresis, which was confirmed by Southern blot hybridization. The results were as follows : 1. As expected, the combined incidence of the common high-risk genital HPVs(types 16, 18 and 33) was high in carcinomas (82.5%) and CIN 111(66.7%), low in CIN 1(33.3%), and nonexistent in the normal controls. 2. By using L1 primers and E1/E2 primers in 46 CINs and cervical carcinomas, HPV DNA was detected in 36(78.3%), which were 65.2%(30/46) for HPV 16, 8.7%(4/46) for HPV 33, 6.5%(3/46) for HPV-18, and only 1 case of mixed infection of HPV-16 and HPV-18 was detected. All normal cervices and cervicitis tissues were negative for HPV 16, 18 and 33. By using E6 primers, 35 (76.1%) cases were positive for HPV DNA, which were 67.4%(31/46) for HPV-16, 4.3%(2/46) each for HPV-18 and HPV-33. HPV 16 is the most common type present in squamous cell carcinoma. 3. There was no difference in detection rates of HPV DNA according to patients age in cervical carcinoma (p=0.188). 4. There were good correlation between the results obtained by PCR using Ll or E1/2 primer and those by E6 primer. The concordance rates were 93.8%(60/64) for HPV-16, 98.4% for HPV-18, and 96.9% for HPV-33. 5. There was no difference in detection rates of HPV DNA according to clinical stage in cervical carcinoma(p=0.2). 6. The detection rate of HPV DNA in case of serum SCC level under lOng/ml was 100%(17/17), which was higher than those in cases of serum SCC levels of 10ng/ml or more. "The detection rate was significantly decreased as serum SCC became high in level(p=0.012). 7. There was no difference in detection rates of HPV DNA according to tumor size in cervical carcinoma (p=0.743). 8. The reccurrence rate of patients with HPV-16 containing tumors was 28.6%((8/28), which was 3.4 times more than that of patients without HPV-16, but it was not statistically significant(p=0.162). The survival rate of patients with HPV-16 containing tumors was 82.1%, which was not different from from that of patients without HPV-16 containing tumrs(p=0.405). In conclusion, papillomavirus, especially HPV-16, played some role in the development of cervical cancer. There was no association between the HPV infection and the clinical characteristics including prognosis. However, in contrast to other studies, HPV type 18 and 33 were not the common type of HPV. Perhaps more cases should be analyzed.

보건소를 이용하는 지역주민의 건강 행위와 건강관련 체력간의 관계

전미양,최명애,이인숙,김태수,김의숙,박선홍 대한보건협회 2002 대한보건연구 Vol.28 No.3

The purpose of this study is to identify relationship health behavior and health related physical fitness in order to provide the basic data for health promotion program for community people. The study was conducted 299 people, during the period from June 1, 2000 to October 30, 2000. The result are as follows. 1. Female comprised was 63.2%(189), while male comprised 36.8%(110). The age range of the subject were from 21 to 59 years old. The subject were aged 30s group 52.5%, 40s group 29.1%, 50s group 12.7%, 20s group 5.7%. Twenty subjects (6.7%) had experience smoking and one subject (0.3%) in female and nineteen subjects (6.4%) in male. Seventy-five subjects (25.1%) had experience drinking and twenty-nine subjects (9.7%) in female, and forty-six (15.4%) in male subjects. ninety-nine subjects had exercise and sixty subjects (20.1%) in female subjects and thirty-mine subject (13%) in male. 2. Body fat and flexibility were higher in female than male subjects, but cardioresperatory endurance, muscular strength and muscular endurance were higher in male than female subjects. 3. There were significant differences in body fat and muscular endurance between age group in both gender subjects, and in cardioresperatory endurance and muscular strength between the age group in male subjects. 4. No significant differences health related fitness between non-smoking and smoking group in both gender subjects. 5. No significant differences health related fitness between non-alcohol and alcohol group in both gender subjects. 6. For female subjects, muscular strength, muscular endurance and flexibility of the exercise group were significantly higher than those of the non exercise group. for male subjects, cardiorespiratory endurance of the exercise group were significantly higher than those of the non exercise group.

鍼灸科 領域에 있어서의 腰脚痛에 對한 臨床的 觀察

金在圭,崔翊善,朴東錫,安秉哲 慶熙大學校韓醫科大學韓醫學硏究所 1980 慶熙韓醫大論文集 Vol.3 No.-

Silica Planar Lightwave Circuit Based Integrated 1 <tex> $\times$</tex> 4 Polarization Beam Splitter Module for Free-Space BB84 Quantum Key Distribution

Choe, Joong-Seon,Ko, Heasin,Choi, Byung-Seok,Kim, Kap-Joong,Youn, Chun Ju IEEE 2018 IEEE photonics journal Vol.10 No.1

<P>We have developed an integrated polarization beam splitter (PBS) module with silica planar lightwave circuit technology for use in BB84 quantum key distribution (QKD). The PBS module is designed to operate on four linear polarizations of the horizontal/vertical/diagonal/antidiagonal direction, and shows the minimum polarization extinction ratio of 17.6 dB. When the module is loaded on the free-space BB84 QKD test-bed, quantum bit error rate and sifted key rate are 2.81% and 415 kb/s at clock rate of 100 MHz, respectively.</P>

In-situ synthesis of Ge/Ti₄O₇ composite with enhanced electrochemical properties

Choe, Hui-Seon,Kim, Min-Cheol,Moon, Sang-Hyun,Kim, Eun-Soo,Kim, Si-Jin,Lee, Gyu-Ho,Won, Ji-Eun,Park, Kyung-Won Elsevier 2018 CERAMICS INTERNATIONAL Vol.44 No.1

<P><B>Abstract</B></P> <P>Germanium (Ge) is a high-capacity material that has been extensively studied due to its relatively high theoretical capacity, excellent electrical conductivity, and high Li diffusion coefficient. However, to overcome the severe volumetric expansion of Ge caused by the alloy/dealloy process during cycling, composite structures consisting of Ge and a highly stable 2nd material need to be developed. In this study, a composite structure consisting of Ge and Ti<SUB>4</SUB>O<SUB>7</SUB> (Ge/Ti<SUB>4</SUB>O<SUB>7</SUB>) is prepared using a facile, in-situ process with GeO<SUB>2</SUB> and TiO<SUB>2</SUB> under an H<SUB>2</SUB> atmosphere at 900°C. Ge/Ti<SUB>4</SUB>O<SUB>7</SUB> exhibits a relatively small particle size of < 1µm compared to pure Ge (> 10µm) prepared in the absence of TiO<SUB>2</SUB>. Ge/Ti<SUB>4</SUB>O<SUB>7</SUB> as an anode for LIB shows a highly reversible capacity and enhanced cycling performance compared to pure Ge electrode. The enhanced electrochemical properties of Ge/Ti<SUB>4</SUB>O<SUB>7</SUB> might be attributed to Ti<SUB>4</SUB>O<SUB>7</SUB> acting as an electronically conductive matrix in the composite, which could buffer the pulverization of Ge during the cycle.</P>

Analysis of size-dependent protein adsorption behavior of Fe₃O₄ nanoparticles

Seon-hwa SEO,Min-seon SONG,Shuwen WANG,Woo-seok CHOE 한국생물공학회 2009 한국생물공학회 학술대회 Vol.2009 No.10

Scolopendra Pharmacopuncture Combined with Electroacupuncture for the Treatment of Ganglion Cysts: A Retrospective Study

Choe, Seon,Jerng, Ui Min,Park, Jeong Hwan,Kim, Sungha,Kim, Sungchul,Lee, Jinbok,Lee, Jun-Hwan,Shin, Minseop KOREAN PHARMACOPUNCTURE INSTITUTE 2020 Journal of pharmacopuncture Vol.23 No.4

Objectives: Ganglion cysts require a sustainable treatment that suppresses their frequent recurrence. This study aimed to explore the clinical effects of Scolopendra pharmacopuncture (SP) and electroacupuncture on ganglion cysts. Methods: We retrospectively reviewed the patient records and follow-up reports for 20 patients with wrist ganglion cysts who received SP and electroacupuncture from April 2016 to March 2017. The cyst diameter, recurrence, visual analog scale (VAS) scores for pain, the Korean version of the disabilities of arm, shoulder, and hand (K-DASH) score, and the Korean version of the patient-rated wrist evaluation (K-PRWE) score before and after treatment were noted. Results: After treatment, the cyst diameter decreased significantly from 13.61 ± 6.41 mm to 5.15 ± 6.18 mm (p < 0.001), and VAS score for pain decreased from 1.31 ± 1.77 to 0.41 ± 0.33 (p = 0.021). Further, the K-DASH score decreased significantly from 8.97 ± 12.66 to 2.21 ± 7.39 (p = 0.016), and score for the function subscale of K-PRWE decreased from 11.37 ± 4.48 to 9.1 ± 3.67 (p = 0.046). No recurrences were reported from the followed-up patients. Any complication related to SP or electroacupuncture was not observed, except mild rash, itching, and swelling at the injection site in four patients. Conclusion: Combination of SP and electroacupuncture may be effective in treating ganglion cysts; further prospective studies with large population are needed to clarify the effect of SP and electroacupuncture.