구내 표준 방사선사진을 이용한 구내방사선촬영기의 선질 평가

이상섭,권혁락,심우현,오승현,이지연,전국진,김기덕,박창서 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.3

Purpose : This study was to evaluate the beam quality of intraoral X-ray equipments used at Yonsei University Dental Hospital (YUDH) using the half value layer (HVL) and the characteristic curve of intraoral standard X-ray film. Materials and Methods : The study was done using the intraoral X-ray equipments used at each clinical department at YUDH. Aluminum filter was used to determine the HVL. Intraoral standard film was used to get the characteristic curve of each intraoral X-ray equipment. Results : Most of the HVLs of intraoral X-ray equipments were higher than the least recommended thickness, but the REX 601 model used at the operative dentistry department and the X-707 model used at the pediatric dentistry department had HVLs lower than the recommended thickness. The slopes of the characteristic curves of films taken using the PANPAS 601 model and REX 601 model at operative dentistry department, the X-705 model of prosthodontic dentistry department, and the REX601 model at the student clinic were relatively low. Conclusion : HVL and the characteristic curve of X-ray film can be used to evaluate the beam quality of intraoral X-ray equipment. In order to get the best X-ray films with the least radiation exposure to patients and best diagnostic information in clinical dentistry, X-ray equipment should be managed in the planned and organized fashion. (Korean J Oral Maxillofac Radiol 2000; 30: 183-188)

차량용 변속기의 조향안전화 제어장치의 개발

송창섭,강서익 한국공작기계학회 1995 한국생산제조학회지 Vol.4 No.2

The operation of heavy tracked vehicle has the problems in the steering that made by misoperations. The protection device is applied to the vehicles. But that device has the engine stop and over load condition problems. The steering safety system is developed on the basis of clutch slip that proved the durability in the dynamo test and field test. The steering safety system caused the performance improvement of vehicles when steering.

산마늘 자생지의 임분구조와 식물종의 연관

김혜진 ( Hye Jin Kim ),윤총원 ( Chung Weon Yun ),도은수 ( Eun Soo Doh ),장준복 ( Jun Pok Chang ),최명석 ( Myung Suk Choi ),양재경 ( Jae Kyung Yang ),박희권 ( Hee Kwon Park ),신학섭 ( Hak Sub Shin ),이서희 ( Seo Hui Lee ),배관호 ( 한국산림과학회 2011 한국산림과학회지 Vol.100 No.4

This study was conducted to describe forest stand characteristics of the habitats of Allium victorialis var. platyphyllum population from the ecological analysis of classification of vegetation types, importance values, species diversity, interspecific association and community similarity in Ulleung Island and Mt. Hambaek, in which investigated by 48 plots (10 m×10 m). The vegetation studied was classified into 1 community group, 2communities, 2 groups and 3 subgroups for a species unit and divided by 5 units for a vegetation unit. In the Fagus engleriana group (vegetation unit 1, 2 and 3), importance value of A. victorialis var. platyphyllum in herb layer showed relatively higher value than other units. Importance value of A. victorialis var. platyphyllum in herb layer had higher value. In the analysis of interspecific association, most of the species associated positively to A. victorialis var. platyphyllum belonged to habitat features of valley area and sub-alpine zone. Therefore, it was considered that the growing environment of A. victorialis var. platyphyllum population was closely correlated to soil moisture and air humidity.

하프코스 마라톤 후 체내의 생화학적 변화 및 회복

최창혁,이현섭,서헌석,김상경,신임희,Choi, Chang-Hyuk,Lee, Hyun-Sub,Seo, Hun-Suk,Kim, Sang-Kyung,Shin, Im-Hee 대한정형외과스포츠의학회 2008 대한정형외과스포츠의학회지 Vol.7 No.1

목적: 하프코스 마라톤 달리기 후에 체내의 생리적 변화를 관찰하여 휴식 기간에 따른 회복 양상을 확인하고자 한다. 대상 및 방법: 하프코스 완주자 13명( 남자 12명, 여자 1명)을 대상으로 하였으며, 평균 연령은 44세(범위: $38{\sim}54$)이었으며 신장은 평균 166 cm (표준편차 6.5), 몸무게는 평균 68 kg(표준편차 7.3)이었다. 생화학적 검사항목은 운동 후 근육 및 심장에 영향을 미치는 혈청효소인 aminotransferases (AST, ALT), CK-MB, Troponin-I 그리고 신장 기능 및 체내의 전해질 균형 상태를 확인할 수 있는 BUN, Creatinine, Na, K의 변화를 확인하였으며, 검사 방법은 출발 전, 완주 직후 및 2일 후, 완주 후 2주에 채혈하여 검사치의 변화의 양상을 확인하였다. 결과: 모든 검사 항목에 있어 측정 시점에 따른 측정 결과는 정상범위 내의 변화를 보였다. 측정 시점에 따른 유의한 변화를 보이지 않았던 검사항목은 ALT (p=0.914) 및 Troponin I (p=0.354)이었으며, BUN, Cr. Na. K등 신장 기능 및 체내의 전해질 균형상태를 반영하는 검사는 완주 직후 증가되었다가 2일 째에 출발전의 수치로 회복되었으며, 근육 및 심장에 영향을 주는 AST 및 CK-MB의 경우 완주 직후 증가된 수치가 2일째까지 유지되거나, 더욱 증가되었다가 2주 후 검사 상 출발전의 수치로 회복되는 양상을 보였다. 결론: 장거리 달리기를 한 후 탈수 현상으로 인한 초기 신장 효소 변화는 2일 정도에 회복이 되었으며, 근육 및 심장의 피로 효소는 약 2주 정도의 시간이 지나야 회복되었다. 따라서 하프코스마라톤을 뛴 후 정상적인 회복을 위해서는 음주경력, 흡연경력 및 달리기 경력에 상관없이 약 2주간의 회복기를 거치는 것이 필요할 것으로 생각되었다. Purpose: To evaluate the recovery time of biochemical changes of body after half-course marathon running. Materials and methods: Thirteen amateur half course marathon runners (12 males and 1 females) were studied. Their average age was 44 years old (range: $38{\sim}54$). Biochemical parameters with blood test including AST, ALT, CK-MB, Treponin, BUN, Cr Na, K were evaluated at finish line, 2nd days, 2nd weeks after running. Results: All the biochemical changes were within normal range throughout recovery time, AST reached its maximum level at finish line and continued until 2nd day after running and returned its pre-running level at 2nd week's test. CK-MB reached its maximum level 2nd day after running and recovered at 2nd week's test. Na, K, BUN and Cr reached to the maximum level at finish line, and recovered to pre-running level at 2nd day's test. Conclusion: In case of half-course marathon, the changes of the kidney enzymes due to dehydration were recovered after 2nd day. And the biochemical indicators of muscle fatigue recovered after 2nd week. It needs at least 2 weeks rest after half-course marathon to recover all the biochemical parameter of the body.

노인성 변화에 따른 안구와 해부생리학적 고찰

김재민,성정섭,서은선,고은경,이석주,유근창,Kim, Jai-Min,Seong, Jeong-Sub,Seo, Eun-Sun,Kho, Eun-Kyung,Lee, Seok-Ju,Yoo, Geun-Chang 한국안광학회 2004 한국안광학회지 Vol.9 No.1

우리 몸은 연령의 증가에 따라 눈과 시력에 노화가 나타난다. 본 연구에서는 안구의 연령에 따른 변화를 노인들을 대상으로 조사하여 연령의 증가에 따른 전안부와 후안부 대한 해부생리학적 변화를 고찰하고자 한다. 광주지역 50-79세 사이의 노령자 219명을 대상으로 문진, 외안부 검사, 시력검사, 눈꺼풀 틈새의 높이와 넓이, 가시홍채직경, 동공크기 등을 측정하였다. 연령의 증가에 따라 50대 이상에서는 눈꺼풀 결막, 각막, 전안방, 홍채, 수정체, 유리체, 맥락막, 망막 및 신경, 암순옹, 대비감도, 굴절이상 등에서 변화가 나타남을 알 수 있다. 눈꺼풀 틈새의 높이와 넓이는 연령의 증가로 젊은이 보다 좁아 졌으나 각막의 수평직경은 거의 변화가 없는 것으로 조사되었다. 따라서 노인의 안구와 시력에 대한 해부생리학적인 정확한 이해가 있어야 노인환자의 안경처방이나 시력관리를 완벽하게 할 수 있을 것으로 사료된다. The Human body is subject to two patterns of senescence, both of which are represented in the eye and vision. This article discusses the anatomical and physiological changes in anterior and posterior segments which occur with age. The areas covered include the globe, lids, tears, conjunctiva, cornea, sclera, anterior chamber angle, iris, lens, choroid, vitreous and retina. A sample of 219 individuals between the ages of 50 and 79 years was tested with case history, slit lamp examination, palpebral fissure, horizontal visible iris diameter(HVID) and pupil size. The palpebral fissure decreases with age while HVID remains constant in all age classes. This study suggests that an understanding of anatomical and physiological changes which occur with age is helpful to all eye clinicians because the aging process affects all of the ocular tissues.

MicroRNA miR-466 inhibits Lymphangiogenesis by targeting prospero-related homeobox 1 in the alkali burn corneal injury model

Seo, Minkoo,Choi, Jun-Sub,Rho, Chang Rae,Joo, Choun-Ki,Lee, Suk Kyeong BioMed Central 2015 JOURNAL OF BIOMEDICAL SCIENCE -BASEL- Vol.22 No.1

<P><B>Background</B></P><P>Lymphangiogenesis is one of the major causes of corneal graft rejection. Among the lymphangiogenic factors, vascular endothelial growth factor (VEGF)-C and -D are considered to be the most potent. Both bind to VEGF receptor 3 (VEGFR3) to activate Prospero homeobox 1 (Prox1), a transcription factor essential for the development and maintenance of lymphatic vasculature. MicroRNAs (miRNAs) bind to the 3' untranslated regions (3' UTRs) of target genes in a sequence-specific manner and suppress gene expression. In the current study, we searched for miRNAs that target the pro-lymphangiogenic factor Prox1.</P><P><B>Results</B></P><P>Among the miRNAs predicted by the bioinformatic analysis to seed match with the 3' UTR of Prox-1, we chose 3 (miR-466, miR-4305, and miR-4795-5p) for further investigation. Both the miR-466 and miR-4305 mimics, but not the miR-4795-5p mimic, significantly reduced the luciferase activity of the Prox-1 3' UTR reporter vector. In primary lymphatic endothelial cells (HDLEC), miR-466 mimic transfection suppressed Prox1 mRNA and protein expression, while miR-4305 mimic transfection did not. Experiments using mutated reporter constructs of the two possible seed match sites on the 3' UTR of Prox1 suggested that the target site 2 directly bound miR-466. HDLEC transfected with the miR-466 mimic suppressed tube formation as compared to the scrambled control. Furthermore, HDLEC transfected with a miR-466 inhibitor showed enhanced tube formation as compared to control inhibitor transfected cells, and this inhibitory effect was counteracted by Prox1 siRNA. The miR-466 mimic reduced angiogenesis and lymphangiogenesis resulting in clearer corneas in an cornea injury rat model compared to the scrambled control.</P><P><B>Conclusions</B></P><P>Our data suggest that miR-446 may have a protective effect on transplanted corneas by suppressing Prox1 expression at the post-transcriptional level. The results of the current study may provide insights into the mechanisms of lymphangiogenesis resulting from corneal graft rejection and alkali-burn injuries, as well as into the development of new treatments for lymphangiogenic eye diseases.</P><P><B>Electronic supplementary material</B></P><P>The online version of this article (doi:10.1186/s12929-014-0104-0) contains supplementary material, which is available to authorized users.</P>

Various Types of Pt-Ni Binary Catalysts Supported on the Carbon Nanotubes as Cathode Catalysts for DMFC

Seo, Yon Ki,Kim, Yong Hwan,Chung, Uoo Chang,Chung, Won Sub Trans Tech Publications, Ltd. 2007 Diffusion and defect data. SSP. [Pt. B], Solid sta Vol.119 No.-

<P>Several methods for loading of Pt-Ni binary catalysts on the CNTs were tested. Using the CNTs treated HNO3, the catalysts supported Pt, Ni separately(Pt&Ni/CNT) and Pt-Ni alloy(Pt- Ni/CNTs) were made respectively. The results of supporting were confirmed by TEM and XRD analysis. TEM images show that metal catalysts were loaded uniformly and finely on the CNTs. By XRD analysis, the peaks of Pt&Ni/CNTs displayed Pt and Ni peaks respectively. Also it was found that the peaks of Pt were shifted to the higher 2theta angle in X-ray diffraction pattern which indicated that Pt-Ni alloy was formed successfully(Pt-Ni/CNTs). In addition, electrochemical tests for cathode catalysts of DMFC were performed. As the results, Pt-Ni/CNTs was most suitable for cathode catalysts of DMFC.</P>

High-dose chemotherapy and autologous peripheral blood stem cell transplantation in the treatment of children and adolescents with Ewing sarcoma family of tumors

Seo, Juhee,Kim, Dong Ho,Lim, Jung Sub,Koh, Jae-Soo,Yoo, Ji Young,Kong, Chang-Bae,Song, Won Seok,Cho, Wan Hyeong,Jeon, Dae-Geun,Lee, Soo-Yong,Lee, Jun Ah The Korean Pediatric Society 2013 Clinical and Experimental Pediatrics (CEP) Vol.56 No.9

Purpose: We performed a pilot study to determine the benefit of high-dose chemotherapy and autologous peripheral blood stem cell transplantation (HDCT/autoPBSCT) for patients with Ewing sarcoma family of tumors. Methods: We retrospectively analyzed the data of patients who received HDCT/autoPBSCT at Korea Cancer Center Hospital. Patients with relapsed, metastatic, or centrally located tumors were eligible for the study. Results: A total of 9 patients (3 male, 6 female), with a median age at HDCT/autoPBSCT of 13.4 years (range, 7.1 to 28.2 years), were included in this study. Patients underwent conventional chemotherapy and local control either by surgery or radiation therapy, and had achieved complete response (CR, n=7), partial response (n=1), or stable disease (n=1) prior to HDCT/autoPBSCT. There was no transplant-related mortality. However, the median duration of overall survival and event-free survival after HDCT/autoPBSCT were 13.3 months (range, 5.3 to 44.5 months) and 6.2 months (range, 2.1 to 44.5 months), respectively. At present, 4 patients are alive and 5 patients who experienced adverse events (2 metastasis, 2 local recur, and 1 progressive disease) survived for a median time of 2.8 months (range, 0.1 to 10.7 months). The 2-year survival after HDCT/autoPBSCT was $44.4%{\pm}16.6%$ and disease status at the time of HDCT/autoPBSCT tended to influence survival ($57.1%{\pm}18.7%$ of cases with CR vs. 0% of cases with non-CR, P=0.07). Conclusion: Disease status at HDCT/autoPBSCT tended to influence survival. Further studies are necessary to define the role of HDCT/autoPBSCT and to identify subgroup of patients who might benefit from this investigational treatment.

Configuration of PV Module Considering the Shadow Condition of PV System

Chang-Uk Lee,Jae-Sub Ko,Tae-Young Seo,Hyouk-Sung Kwon,Dong-Hwa Chung 제어로봇시스템학회 2014 제어로봇시스템학회 국제학술대회 논문집 Vol.2014 No.10

This paper proposes the re-configuration of photovoltaic(PV) module considering the environment conditions of the PV system. The PV system is consisted of the series-parallel connection of the PV module. When shadows or changes of the radiation or an electrical characteristic in the solar cell are happened to PV system, the serious power loss will occur. If the PV module connected in series has the shadows, the output current is restricted to current of shaded PV module. Also if shadow is occurred to the parallel connection PV module, the output voltage is limited to voltage of shaded PV module. These problems are caused power loss. Therefore, this paper proposes the method that makes the output power of the PV module equalize by reconfiguration of PV module using the switching considering these environment conditions. A validity of the method proposed in this paper proves through comparing with performance of conventional PV module.

MPPT Control of Photovoltaic System using FLC-PI Controller

Chang-Uk Lee,Jae-Sub Ko,Tae-Young Seo,Dong-Hwa Chung4 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10