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Park, Jong-Hyun,Noh, Jin-Chul,Park, Hyang-Mi,Jung, Yu-Soek,Park, Sei-Hyeog,Hong, H. Christian,Shin, Hye-Jung The Korean Society of Pediatric Gastroenterology 2012 Pediatric gastroenterology, hepatology & nutrition Vol.15 No.1
Cholelithiasis and choledocholithiasis are uncommon pediatric diseases, although clinicians have seen them with increasing frequency in children in recent years. Moreover, no case of Epstein-Barr virus (EBV) infection with cholelithiasis and choledocholithiasis has been previously reported in the English literature. We report a pediatric patient with EBV infection, a gall bladder stone, and a common bile duct stone, may have had GB and CBD stones prior to her EBV infection, whom we successfully treated with antibiotics and laparoscopic cholecystectomy for cholecystitis.
박세혁(Sei Hyeog Park),임선구(Sun Gu Lim),양시준(Shi Jun Yang),김종흥(Jong Heung Kim) 한국간담췌외과학회 2010 한국간담췌외과학회지 Vol.14 No.1
Gallbladder carcinoma is the most common primary hepatobiliary carcinoma and the fifth most common malignancy of the GI tract. The most common type of gallbladder carcinoma is adenocarcinoma. Squamous cell carcinoma of the gallbladder is rarer and is responsible for up to 12.7% of gallbladder tumors. A 78-year-old man was incidentally suspected of having a gallbladder mass on an abdominal CT scan and underwent laparoscopic cholecystectomy. Pathology results confirmed the mass as a squamous cell carcinoma. Here we report a case of keratinizing squamous cell carcinoma of the gallbladder and review the literature.
Jong Hyun Park,Hye Jung Shin,Jin Chul Noh,Hyang Mi Park,Yu Soek Jung,Sei Hyeog Park,H. Christian Hong 대한소아소화기영양학회 2012 Pediatric gastroenterology, hepatology & nutrition Vol.15 No.1
Cholelithiasis and choledocholithiasis are uncommon pediatric diseases, although clinicians have seen them with increasing frequency in children in recent years. Moreover, no case of Epstein-Barr virus (EBV) infection with cholelithiasis and choledocholithiasis has been previously reported in the English literature. We report a pediatric patient with EBV infection, a gall bladder stone, and a common bile duct stone, may have had GB and CBD stones prior to her EBV infection, whom we successfully treated with antibiotics and laparoscopic cholecystectomy for cholecystitis.
박인규(In-Kyu Park),오흥권(Heung-kwon Oh),박세혁(Sei Hyeog Park),박종민(Jong-Min Park) 대한종양외과학회 2012 Korean Journal of Clinical Oncology Vol.8 No.2
목적 : 사회경제적 위치에 따라 위암 환자의 임상 결과에 차이가 있다는 여러 연구결과가 있음에도 불구하고 우리나라에서는 연구가 부족한 실정이다. 이 연구는 공공병원에서 위암으로 수술을 시행 받은 환자의 건강보험 종류에 따른 단기 임상 결과의 차이를 알아보고자 하였다. 대상 및 방법 : 2007년 3월부터 2012년 7월까지 위암으로 수술을 시행 받은 186명의 환자들을 후향적으로 분석하였다. 사회경제적 위치는 의료급여 수급권자를 하위 계층으로, 건강보험 가입자를 상위 계층으로 구분하여 수술 후 임상 결과를 조사하였다. 결과 : 186명의 환자 중 의료급여 수급권자는 81명, 건강보험 가입자는 105명이었다. 각 군의 평균연령은 63.6세와 65.3세, 동반질환은 65.4%와 78.1% 무증상 검진율은 32.1%와 46.7%였다. 근치적 절제율은 74.1%와 85.7%, 합병 절제율은 34.6%와 21.9%, 조기 위암의 비율은 33.3%, 51.4%로 의료 급여 수급권자에서 진행된 병기의 환자가 많았다. 근치적 절제 후 재발율은 16.7%와 5.6%였다. 결론 : 의료급여 수급권자들의 경우 조기 진단이 늦어져 진행성 위암의 비율이 높았으며, 수술 시 근치적 절제율이 낮고, 재발율 또한 높게 나타남을 알 수 있었다. Introduction : Although there are several studies which have shown the difference between the clinical outcome and socioeconomic status, there is still insufficient research in Korea. This study will show the difference of short term clinical outcome according to the type of health insurance for patients who have had surgery for gastric cancer in public hospital. Methods : From March 2007 to July 2012, 186 patients who underwent surgery for gastric cancer were retrospectively analyzed. Patients were examined by socioeconomic status. It classified patient in two groups. One was lower class for patients who were beneficiaries of medical aid. Another was upper class for patients who benefitted from health insurance. Results : 186 patients were 81 beneficiaries and 105 health insurance patients. The mean age was 63.6 years and 65.3 years for each group. Comorbidity disease was 65.4% and 78.1%. Asymptomatic checkup rate was 32.1% and 46.7%. Radical resection was 74.1% and 85.7%. Combined resection was 34.6% and 21.9%. There were many currently advanced stage patients in beneficiaries. The recurrence rate was 16.7% and 5.6% after radical resection. Conclusions : Medical aid beneficiaries had the higher proportion of progressive gastric cancer due to lack of an early screening and the low radical resection rate after undergoing operation. The rate of recurrence was high for beneficiaries too.
박재민(Jae Min Park),김은영(Eunyoung Kim),정일용(Il Yong Chung),박세혁(Sei-Hyeog Park),박종민(Jong-Min Park),윤여규(Yeo-Kyu Youn),오흥권(Heung-Kwon Oh),김중석(Joong-Suck Kim),주성홍(Sung-Hong Joo) 대한종양외과학회 2014 Korean Journal of Clinical Oncology Vol.10 No.2
Purpose: In this study, we compared characteristics of cancer of North Korean defectors to South Korean. In order to clarify the clinicopathologic characteristics of cancer in North Korean defectors. Methods: This study is a retrospective study through chart review of patients diagnosed as cancer at National Medical Center from 2008 to 2013. Control group included South Korean cancer patients who were diagnosed as cervical cancer, thyroid cancer, liver cancer, stomach cancer at same hospital during same period. Two groups were analyzed and compared by sex, age, past medical history, cancer origin, cancer stage, and treatment. Results: Among 1,760 North Korean defector patient registered in National Medical Center, 61 patients were diagnosed as cancer, which was 3.5%. Cervical cancer (19.7%), thyroid cancer (19.7%), liver cancer (14.1%) and stomach cancer (10.3%) were 4 most frequent cancer. In South Korean cancer patient, percentage was as follows: thyroid cancer (33.7%), stomach cancer (7.8%), liver cancer (7.3%), cervical cancer (3.7%). Conclusion: Cancers closely related to socio-economic status, such as cervical cancer and hepatitis-B related liver cancer, were relatively more frequent in North Korean defectors than South Koreans. As for cancers in which early diagnosis is important such as thyroid cancer and stomach cancer, there were no significant differences in age-prevalence, disease course and treatment.
최혁기 ( Hyeog Gi Choi ),김창현 ( Chang Hyun Kim ),박시내 ( Shi Nae Park ),최미영 ( Mi Yung Choi ),남승규 ( Seung Gyu Nam ),박성천 ( Sung Chun Park ),이성재 ( Sung Jae Lee ),이종민 ( Chong Min Lee ),이세윤 ( Sei Yun Lee ),여상원 ( 한국조직공학·재생의학회 2009 조직공학과 재생의학 Vol.6 No.4
The somatic stem cells in the auditory organs can be utilized for the treatment of sensory neuronal hearing loss. The aim of this study was to isolate and culture of adult stem cells from guinea pig spiral ganglion in order to investigate the presence of soamtic stem cells in auditory organs of adult mammals. Spiral ganglions were obtained from the cochlea of guinea pigs, which weigh about 300 g. The tissues were dissociated and cultured in a medium added with epidermal growth factor and fibroblast growth factor. Then they were labeled with many markers for the stem cells and their differentiated cells, and identified under immunofluorecence microscope to find out the presence of somatic stem cells. The cultured cells can differentiate into neuronal cells positive for β III tubulin and glial cells positive for S-100. They were confirmed to be differentiated cells from neurosphere as the positive results for known stem cell marker such as bromodeoxyuridine(BrdU) and nestin. It was confirmed that the neural stem cells were existed in the spiral ganglion of guinea pig, which have the capability of self renewal and differentiation into specific neural cells. This fact presents a possibility of stem cell treatment for the patients of hearing impairment.
최병서,오흥권,Sei Hyeog Park,박중민 대한위암학회 2013 Journal of gastric cancer Vol.13 No.1
Purpose: Laparoscopic gastrectomy has been adopted for the treatment of gastric cancer, and despite the technical difficulties, totally laparoscopic distal gastrectomy has been considered less invasive than laparoscopy-assisted distal gastrectomy. Although there have been many reports regarding the feasibility and safety of totally laparoscopic distal gastrectomy at large volume centers, few reports have been conducted at low-volume centers. The purpose of this study is to try to assess the feasibility and safety of totally laparoscopic distal gastrectomy at a low volume center through the analysis of short-term outcomes of totally laparoscopic distal gastrectomy compared with laparoscopy-assisted distal gastrectomy. Materials and Methods: The clinical data and short-term surgical outcomes of 35 patients who had undergone laparoscopy-assisted distal gastrectomy between April 2007 and March 2010, and 37 patients who underwent totally laparoscopic distal gastrectomy between April 2010 and August 2012 were retrospectively reviewed. Results: There was no significant difference in the demographic and clinical data. However the reconstruction method and extent of lymphadenectomy showed statistically significant differences. Operation time and estimated blood loss did not show significant differences. Surgical and medical complications did not show significant differences but postoperative courses including time-to-first oral intake and postoperative hospital stay were significantly increased. Conclusions: Our study shows that totally laparoscopic distal gastrectomy is technically feasible at a low volume center. Therefore, totally laparoscopic distal gastrectomy can be considered as one of the surgical treatment for early gastric cancer. However the possibility that totally laparoscopic distal gastrectomy may have less benefit should also be considered.
Byeonghun Oh,Sei Hyeog Park,Eunyoung Kim,Eun Jeong Ahn,Jong-Min Park 대한내시경복강경외과학회 2016 Journal of Minimally Invasive Surgery Vol.19 No.2
Purpose: Several studies have reported that laparoscopic cholecystectomy with percutaneous transhepatic gallbladder drainage (PTGBD) is associated with a reduced duration of surgery and a lower rate of conversion to open laparotomy compared with laparoscopic cholecystectomy without PTGBD and delayed laparoscopic cholecystectomy after conservative therapy. However, these results are contradictory. This retrospective study investigated the safety and the usefulness of laparoscopic cholecystectomy combined with pre-operative PTGBD in patients with acute cholecystitis. Method: The clinicopathologic data and surgical outcomes of 101 patients who underwent laparoscopic cholecystectomy between January 2010 and September 2015 were retrospectively reviewed. Result: Patients in the PTGBD group vs. the non-PTGBD group were significantly older (mean age: 65.47 ± 12.2 vs. 56.32 ± 13.7; p = 0.001). Underlying diseases were also significantly more common in the PTGBD group (75.4% vs. 45.5%; p = 0.002). There were no significant differences between the two groups in terms of operative time, blood loss, rate of open conversion, postoperative oral intake, postoperative hospital stay. Total hospital day was significantly longer in the PTGBD group (11.14 ± 7.22 vs. 6.23 ± 5.17; p = 0.049). There was no significant difference in the postoperative complications between the two groups. All patients in this study lived. Conclusion: This study suggested that satisfactory results can be achieved with selective preoperative PTGBD in older and sicker patients with acute cholecystitis.