http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : 최미영 ( Mi Yung Choi ) (검색결과 3 건)
- 무료
- 기관 내 무료
- 유료
-
최혁기 ( Hyeog Gi Choi ),김창현 ( Chang Hyun Kim ),박시내 ( Shi Nae Park ),최미영 ( Mi Yung Choi ),남승규 ( Seung Gyu Nam ),박성천 ( Sung Chun Park ),이성재 ( Sung Jae Lee ),이종민 ( Chong Min Lee ),이세윤 ( Sei Yun Lee ),여상원 ( 한국조직공학·재생의학회 2009 조직공학과 재생의학 Vol.6 No.4
The somatic stem cells in the auditory organs can be utilized for the treatment of sensory neuronal hearing loss. The aim of this study was to isolate and culture of adult stem cells from guinea pig spiral ganglion in order to investigate the presence of soamtic stem cells in auditory organs of adult mammals. Spiral ganglions were obtained from the cochlea of guinea pigs, which weigh about 300 g. The tissues were dissociated and cultured in a medium added with epidermal growth factor and fibroblast growth factor. Then they were labeled with many markers for the stem cells and their differentiated cells, and identified under immunofluorecence microscope to find out the presence of somatic stem cells. The cultured cells can differentiate into neuronal cells positive for β III tubulin and glial cells positive for S-100. They were confirmed to be differentiated cells from neurosphere as the positive results for known stem cell marker such as bromodeoxyuridine(BrdU) and nestin. It was confirmed that the neural stem cells were existed in the spiral ganglion of guinea pig, which have the capability of self renewal and differentiation into specific neural cells. This fact presents a possibility of stem cell treatment for the patients of hearing impairment.
-
난청 동물모델에서 신경성장인자에 의한 청력회복과 나선 신경절재생에 관한 연구
오정훈 ( Jung Hoon Oh ),박시내 ( Shi Nae Park ),최혁기 ( Hyeog Gi Choi ),최미영 ( Mi Yung Choi ),한민아 ( Min Ah Han ),박경호 ( Kyoung Ho Park ),여상원 ( Sang W. Yeo ) 한국조직공학·재생의학회 2008 조직공학과 재생의학 Vol.5 No.4
Cochlear prostheses for the sensorineural hearing impairment are dependent on survival and excitability of the auditory nerve. Multiple neurotrophic factors have been shown to have important roles in the survival of auditory neurons and protecting spiral ganglion cells. This study evaluated the efficacy of brain-derived neurotrophic factor(BDNF) combined with glial-cell derived neurotrophic factor(GDNF) and neurotrophin-3(NT-3), insulin growth factor(IGF), and epidermal growth factor(EGF) with fibroblast growth factor(FGF) application in 2 weeks post-deafening guinea pigs. Healthy 30 guinea pigs were deafened by infusion of kanamycin and ethacrynic acid. Myringotomy was done in both ears, gelfoams immersed with neurotrophic factors were placed on the round window membrane while gelfoams immersed with saline were applied to control ear. On 1 week after drug application, hearing test was done and the cochleae were collected in every 2 weeks. And the number of spiral ganglion cells was quantitatively analyzed. Significant hearing restoration was observed in group 1(BDNF, GDNF, NT-3 treated group) & group 2(IGF treated group). The number of spiral ganglion cells of group 1 on 5 week after the treatment, and group 3(EGF, FGF treated group) on 3 week after the treatment were significantly increased them compared with control group. However, no statistically significant regeneration was observed in group 2. These findings demonstrate that BDNF+GDNF+NT-3 neurotrophic factor application through round window membrane have the potential for regeneration of spiral ganglion cells & hearing restoration.
-
Neostigmine 투여후 Succinylchline 의 근이완 회복 지연
신양식,박광원,남순호,최미영 대한마취과학회 1992 Korean Journal of Anesthesiology Vol.25 No.1
We report a case of slow recovery of the neuromuscular block induced by succinylcholine (SCC) immediately after administration of neostigmine for the reversal of pancuronium. Left hemithyroidectomy was performed in a 4l kg female patient under general endotracheal inhalation anesthesia with 50%-nitrous oxide and 2.0%-enflurane. Four mg of pancuronium was used for muscular relaxation to facilitate the controlled ventilaion on the anesthesia ventilator. At the end of the operation, one and a half hours from the injection of pancuronium, 10 mg of pyridostigmine was administered to reverse the neuromuscular blockade. Five minutes later, 25 mg of succinylcholine was given for reintubation. Following this event, train-of-four stimuli was applied under the uncalibrated mode with Datex Relaxograph because apnea followed by SCC appeared for more than 30 minutes. Neuromuscular monitoring revealed fade to less than 50% of the T, ratio. The ventilator was applied for the recovery of neuromuscular blockade for one hour. There was no more late complications after transfer to the ward. The literature relating to this iatrogenic complication and phase II block after SCC is reviewed and discussed.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
