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      • An Improved Intrusion Detection System for SDN using Multi-Stage Optimized Deep Forest Classifier

        Saritha Reddy, A,Ramasubba Reddy, B,Suresh Babu, A International Journal of Computer ScienceNetwork S 2022 International journal of computer science and netw Vol.22 No.4

        Nowadays, research in deep learning leveraged automated computing and networking paradigm evidenced rapid contributions in terms of Software Defined Networking (SDN) and its diverse security applications while handling cybercrimes. SDN plays a vital role in sniffing information related to network usage in large-scale data centers that simultaneously support an improved algorithm design for automated detection of network intrusions. Despite its security protocols, SDN is considered contradictory towards DDoS attacks (Distributed Denial of Service). Several research studies developed machine learning-based network intrusion detection systems addressing detection and mitigation of DDoS attacks in SDN-based networks due to dynamic changes in various features and behavioral patterns. Addressing this problem, this research study focuses on effectively designing a multistage hybrid and intelligent deep learning classifier based on modified deep forest classification to detect DDoS attacks in SDN networks. Experimental results depict that the performance accuracy of the proposed classifier is improved when evaluated with standard parameters.

      • KCI등재

        Semi solid matrix formulations of meloxicam and tenoxicam: an in vitro and in vivo evaluation

        Saritha Alladi,Nalini R. Shastri 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.5

        The objective of this study was to improve thedissolution and subsequently the therapeutic efficacy ofpoorly water soluble BCS class-II drugs meloxicam andtenoxicam, by lipid semi solid matrix (SSM) systems filledin hard gelatin capsules by liquid fill technology. Thepresent research involved preparation of SSM formulationsusing Gelucire 44/14 as a carrier due to its self emulsifying,wetting and hydrophilic properties. The SSM capsuleswere characterized by assay, in vitro dissolution studies,moisture uptake, FTIR and DSC. The optimized formulationswere also evaluated for their in vivo anti inflammatoryactivity in rat model. Six to ten fold enhancementin vitro drug release, in both acidic and basic media, wasobtained with formulations containing drug to carrier in 1:6ratio. The absence of drug peak in DSC scans indicatedcomplete dissolution of the drug in carrier, while IRrevealed no chemical interaction of pure drug and Gelucire44/14. The optimized SSM formulations of meloxicam andtenoxicam showed a rapid decrease in paw edema with asignificant increase in anti-inflammatory activity. The SSMformulations were successful in providing rapid release ofdrugs with improved dissolution and in vivo anti-inflammatoryactivity by liquid fill technology in hard gelatincapsules.

      • KCI등재

        Change detection in urban landscapes: a tensor factorization approach

        S. Saritha,G. Santhosh Kumar 대한공간정보학회 2019 Spatial Information Research Vol.27 No.5

        Analysis of urban landscape has been an interesting research challenge for decades. The advent of machine learning and data mining techniques have geared the problem from simple analysis of data to knowledge discovery from data. This work attempts to mine urban landscapes to find the change pattern which has happened over the region for a period of interest. The work proposes a spatiotemporal-metric miner, which uses the spatial, temporal and landscape metric data to discover the change that has occurred in a region. The model works on a hierarchical basis, wherein, the regions of interest are chosen in a landscape and are aggregated to find the change that has happened over the entire region. The entire model is built by taking advantage of the tensorized representation of data, and thus resulting in the effective mining of tensors. The growth of a landscape is evaluated regarding two parameters, namely, Inter-class Growth Index and Intra-class Growth Index. Experiments are performed on the landscape regions of Indian cities, and a ranking of cities is presented based on the growth indices, which are validated against standards. In the experiments, Jaipur city showed the highest Inter-class Growth Index value of 2.68 and Surat city had an Intra-class Growth Index of 0.78.

      • SCOPUSSCIEKCI등재

        The global distribution of permanent canine hypodontia: A systematic review

        Sivarajan, Saritha,Mani, Shani Ann,John, Jacob,Fayed, Mona M. Salah,Kook, Yoon-Ah,Wey, Mang Chek The Korean Association Of Orthodontists 2021 대한치과교정학회지 Vol.51 No.1

        Objective: To systematically review studies on canine agenesis prevalence in different populations and continents, based on the jaw, sex, location, and associated dental anomalies. Methods: Electronic and hand searches of English literature in PubMed, Web of Science, Scopus, OpenGrey, and Science Direct were conducted, and the authors were contacted when necessary. Observational studies (population-based, hospital/clinic-based, and cross-sectional) were included. For study appraisal and synthesis, duplicate selection was performed independently by two reviewers. Study quality was assessed using a modified Strengthening the Reporting of Observational Studies in Epidemiology checklist, with main outcome of prevalence of canine agenesis. Results: The global population prevalence of canine agenesis was 0.30% (0.0-4.7%), highest in Asia (0.54%), followed by Africa (0.33%), and the least in Europe and South America (0.19% in both continents). Canine agenesis was more common in the maxilla (88.57%), followed by both maxilla and mandible (8.57%), and the least common was mandible-only presentation (2.86%). The condition was more common in females (female:male ratio = 1.23), except in Asia (female:male ratio = 0.88) and Africa (female:male ratio = 1). In Asia, unilateral agenesis was almost twice as prevalent as bilateral, but in Europe, the bilateral form was more common. Conclusions: The overall prevalence of canine agenesis is 0.30%, with the highest prevalence in Asia, followed by Africa, Europe, and South America. The condition is more common in the maxilla than the mandible, and in females than males (except in Asia and Africa), with unilateral agenesis being more common in Asia and the bilateral form showing a greater prevalence in Europe.

      • SCISCIESCOPUS

        Ratiometric fluorescence chemosensor based on tyrosine derivatives for monitoring mercury ions in aqueous solutions

        Thirupathi, Ponnaboina,Saritha (né,e Gudelli), Ponnaboina,Lee, Keun-Hyeung The Royal Society of Chemistry 2014 Organic & Biomolecular Chemistry Vol.12 No.36

        <P>Ratiometric fluorescent chemosensors <B>1</B> and <B>2</B> were synthesized based on tyrosine amino acid derivatives with a pyrene fluorophore. <B>1</B> and <B>2</B> showed high selectivity for Hg(<SMALL>II</SMALL>) ions among 13 metal ions in aqueous solutions. Both <B>1</B> and <B>2</B> sensitively detected Hg(<SMALL>II</SMALL>) ions in aqueous solutions by ratiometric response without interference of any of the other tested metal ions including Cu(<SMALL>II</SMALL>), Cd(<SMALL>II</SMALL>), Pb(<SMALL>II</SMALL>), and Ag(<SMALL>I</SMALL>) ions. <B>1</B> and <B>2</B> had tight binding affinities (5.72 × 10<SUP>13</SUP> M<SUP>−2</SUP>, 1.15 × 10<SUP>13</SUP> M<SUP>−2</SUP>) for Hg(<SMALL>II</SMALL>) with nano-molar detection limits. The binding mode was characterized with the help of organic spectroscopic data, which revealed that the methoxyphenyl moieties of <B>1</B> and <B>2</B> played a vital role in the coordination of Hg(<SMALL>II</SMALL>). The deprotonation of the sulfonamide group is not a critical process for the binding of mercury ions. The methoxyphenyl moiety, sulfonamide group, and the C-terminal amide moiety of <B>1</B> and <B>2</B> as ligands for Hg(<SMALL>II</SMALL>) played crucial roles in the stabilization of the 2 : 1 complexes.</P> <P>Graphic Abstract</P><P>Ratiometric fluorescent chemosensors <B>1</B> and <B>2</B> were synthesized based on tyrosine amino acid derivatives with a pyrene fluorophore. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4ob01044b'> </P>

      • SCOPUSKCI등재

        Sperm DNA fragmentation negatively influences the cumulative live birth rate in the intracytoplasmic sperm injection cycles of couples with unexplained infertility

        Repalle, Deepthi,Saritha, Kallimakula Venkata Reddy,Bhandari, Shilpa The Korean Society for Reproductive Medicine 2022 Clinical and Experimental Reproductive Medicine Vol.49 No.3

        Objective: This study aimed to determine the effect of sperm DNA fragmentation (SDF) on the cumulative live birth rate (CLBR) in intracytoplasmic sperm injection (ICSI) cycles in couples with unexplained infertility. Methods: We conducted a prospective study of 145 couples who underwent ICSI cycles for unexplained infertility. Based on the SDF rate, patients were categorized into a low SDF group (SDF ≤30%, n=97) and a high SDF group (SDF >30%, n=48). SDF was assessed using the acridine orange test on density gradient centrifugation prepared samples. The CLBR was calculated as the first live birth event per woman per egg collection over 2 years. Results: The high SDF group (SDF >30%) showed a significantly lower CLBR (p<0.05) and a significantly higher miscarriage rate (p<0.05) than the low SDF group (SDF ≤30%). No significant difference was observed in the implantation and cumulative pregnancy rates between the two SDF groups. The total number of embryo transfers was stratified further into fresh and frozen embryo transfers. In the fresh embryo transfers, there were significant differences in the implantation rates, clinical pregnancy rates, and live birth rates (p<0.05) between the low SDF and high SDF groups. However, in the frozen embryo transfers, there were no significant differences in clinical outcomes between the two groups. In the multivariable logistic regression analysis, SDF was a predictor of CLBR (p<0.05) when adjusted for possible confounding factors. Conclusion: High SDF was associated with a lower CLBR and a higher miscarriage rate in the ICSI cycles of couples with unexplained infertility.

      • KCI등재

        Boron-rich boron carbide from soot: a low-temperature green synthesis approach

        Swapna M. S.,Saritha Devi H. V.,Sankararaman S. 한국세라믹학회 2020 한국세라믹학회지 Vol.57 No.6

        Boron carbide is a promising super-hard semiconducting material for refractory applications ranging from the nuclear industry to spacecraft. The present work is the fi rst report of not only turning futile soot, containing carbon allotropes in varying composition, into boron-rich boron carbide (BC), but also developing it by a low-cost, low-temperature, and green synthesis method. The BC synthesised from gingelly oil soot is subjected to structural, morphological, and optical characterisations. The fi eld emission scanning electron microscope shows beautiful fl ower-like morphology, and the thermogravimetric analysis reveals the high-temperature stability of the sample synthesised. The Tauc plot of the sample indicates a 2.38 eV direct bandgap. The formation of BC and boron-rich carbide evidenced by X-ray diff raction studies is confi rmed through Raman and Fourier transform infrared spectroscopic signatures of B–C and C–B–C bonds. The fl uorescence, power spectrum, and CIE analyses carried out suggest the blue light emission for excitation at 350 nm.

      • KCI등재

        Effect of annealing on the physical properties of thermally evaporated In2S3 thin films

        S. Rasool,K. Saritha,K.T. Ramakrishna Reddy,M.S. Tivanov,A.V. Trofimova,S.E. Tikoto,L. Bychto,A. Patryn,M. Maliński,V.F. Gremenok 한국물리학회 2019 Current Applied Physics Vol.19 No.2

        The structural, compositional, morphological and optical properties of In2S3 thin films, prepared by thermal evaporation technique and annealed in sulfur ambient at different temperatures have been investigated. The grazing incident X-ray diffraction patterns have indicated polycrystalline form and predominantly cubic structure of annealed In2S3 films. The scanning electron microscopy revealed textured surface with uniformly distributed grains and the grain size increased with increase of annealing temperature. The optical parameters of the films have been determined using conventional transmission and reflection spectra as well as from surface photovoltage measurements.

      • KCI등재

        Synthesis, Characterization and Determination of HOMO-LUMO of the Substituted 1,3,5-Triazine Molecule for the Applications of Organic Electronics

        Pakkath, Rajeesh,Reddy, Eeda Koti,Kuriakose, Sheena,Saritha, C,Sajith, Ayyiliath M,Karuvalam, Ranjith Pakkath,Haridas, Karickal Raman Korean Chemical Society 2019 대한화학회지 Vol.63 No.5

        The most important parameter of organic molecules for energy harvesting application focuses mainly on their band gap (HOMO-LUMO). In this report, we synthesized differently substituted 1,3,5-triazine based organic molecule which on future processing can be used in organic electronics like solar cells and OLED's. The energy gap of the synthesized novel analogue was calculated using cyclic voltammetry, UV-Visible spectroscopy and compared with density functional theory (DFT) studies.

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