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      • KCI등재후보

        A Modified Single Port Minimally Invasive Video Assisted Thyroid and Parathyroid Surgery Technique Using Tubular Retractor System

        Yadav Sanjay Kumar,Jha Chandan Kumar,Johri Goonj 대한내분비외과학회 2021 The Koreran journal of Endocrine Surgery Vol.21 No.2

        Minimally invasive video assisted thyroid and parathyroid surgery (MIVAT/MIVAP) has become a common approach worldwide and is being performed for malignant thyroid nodules and bilateral neck exploration for parathyroid as well (1). It is a central gasless approach as compared to the endoscopic approach proposed by Gagner (2) and other approaches described using CO2 insufflation, external retraction, lateral access as proposed by Henry et al. (3). The advantages of MIVAT/MIVAP are smaller incision, early post-operative recovery and lesser pain leading to better patient satisfaction. Other advantages arise due to the use of magnifying endoscope enabling an easier identification of the recurrent laryngeal nerves (RLNs), external branch of superior laryngeal nerves and parathyroids (4). We here describe a modified single port MIVAT/MIVAP technique using tubular retractor system.

      • SCISCIESCOPUS

        Fluorescence sensing of Cu<sup>2+</sup> ion and imaging of fungal cell by ultra-small fluorescent carbon dots derived from <i>Acacia concinna</i> seeds

        Bhamore, Jigna R.,Jha, Sanjay,Park, Tae Jung,Kailasa, Suresh Kumar Elsevier 2018 Sensors and actuators. B Chemical Vol.277 No.-

        <P><B>Abstract</B></P> <P>In this work, we explored the use of <I>Acacia concinna</I> seeds (shikakai) as a green precursor for the fabrication of ultra-small fluorescent carbon dots (CDs). The synthesized ultra-small fluorescent CDs sense only Cu<SUP>2+</SUP> ion through strong chelation between Cu<SUP>2+</SUP> ion and organic groups of CDs. As a result, highly selective fluorescence “turn-off” probe was developed for assay of Cu<SUP>2+</SUP> ion, causing remarkable fluorescence intensity quenching, which has ability to sense Cu<SUP>2+</SUP> ion even at 0.0043 μM (4.3 nM). Furthermore, the ultra-small fluorescent CDs act as biocompatible probes for multicolour imaging of fungal (<I>Penicillium</I> sp.) cells. The practical application of the developed sensor was demonstrated by assaying of Cu<SUP>2+</SUP> ion in spiked water samples, which confirms their significant analytical and bioanalytical applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Fabrication of fluorescent shikakai CDs from <I>Acacia concinna</I> fruit. </LI> <LI> Shikakai CDs act as fluorescent sensor for Cu<SUP>2+</SUP> ion sensing. </LI> <LI> Shikakai CDs-based fluorescent platform exhibited higher sensitivity. </LI> <LI> Shikakai CDs act as strong chelator to trap Cu<SUP>2+</SUP> ion, shows detection limit of 0.0043 μM. </LI> <LI> Multi-color fungal cell imaging was carried out using shikakai CDs. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Synthesis of fluorescent carbon dots from shikakai for fluorescence detection of Cu<SUP>2+</SUP> ion and fungal cell imaging.</P> <P>[DISPLAY OMISSION]</P>

      • SCISCIESCOPUS

        Facile green synthesis of carbon dots from <i>Pyrus pyrifolia</i> fruit for assaying of Al<sup>3+</sup> ion <i>via</i> chelation enhanced fluorescence mechanism

        Bhamore, Jigna R.,Jha, Sanjay,Singhal, Rakesh Kumar,Park, Tae Jung,Kailasa, Suresh Kumar Elsevier 2018 Journal of molecular liquids Vol.264 No.-

        <P><B>Abstract</B></P> <P>In this work, we synthesized fluorescent carbon dots (CDs) using <I>Pyrus pyrifolia</I> (pear) fruit <I>via</I> hydrothermal method at 180 °C for 6 h without using any further treatment or surface passivating agents. The synthesized CDs possess intense blue fluorescence under UV lamp at 365 nm and exhibit emission peak at 471 nm when excited at 390 nm. Because of specific surface functional groups, the synthesized CDs showed high selectivity to detect Al<SUP>3+</SUP> ion through chelation enhanced fluorescence (CHEF) mechanism. The emission peak intensity of CDs at 471 nm was gradually enhanced with increasing concentration of Al<SUP>3+</SUP> ion, thereby Al<SUP>3+</SUP> ion was quantified by plotting calibration curve over the range of 0.005–50 μM with a detection limit of 0.0025 μM (2.5 nM). The nanoprobe was subsequently evaluated by assaying Al<SUP>3+</SUP> ion from spiked water samples, signifying the utility of nanoprobe for assaying of Al<SUP>3+</SUP> ion real samples. Furthermore, we also demonstrate that the bioimaging ability of CDs for imaging of <I>Bacillus subtilis</I> bacterial cell, suggesting that the nanoprobe can be used for cell imaging applications.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Fluorescent carbon dots are derived from <I>Pyrus pyrifolia</I> (pear) fruit. </LI> <LI> Al<SUP>3+</SUP> ion was detected <I>via</I> chelation enhanced fluorescence mechanism. </LI> <LI> Al<SUP>3+</SUP> ion detection limit is 0.0025 μM (2.5 nM). </LI> <LI> The CDs acted as probes for imaging of <I>Bacillus subtilis</I> bacterial cells. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Schematic representation for fabrication of CDs using pear fruit and sensing of Al<SUP>3+</SUP> ion <I>via</I> chelation enhanced fluorescence mechanism.</P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Prediction of weld zone shape with effect of tool pin profile in friction stir welding process

        Prashant Prakash,Ravi Shankar Anand,Sanjay Kumar Jha 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.1

        This article investigates the effect of tool pin profile on weld zone shape using computational fluid dynamics techniques in friction stir welding process. The effect of tool pin profile on weld zone shape was investigated by four different pin profile tools: Cylindrical, conical, cylindrical-conical and stepped-conical. In the numerical simulation process, workpiece material and tool are considered as non-Newtonian fluids and solid material, respectively. And simulation is carried out under transient state condition. Temperature distribution and material flow profile developed by the tool pin profile are analyzed for the understanding of viscosity profile of the weld zone region. Critical iso-viscosity surface is developed from the viscosity profile to determine the difference between deformed and undeformed material, which is finally used to determine the weld zone shape. The simulation result shows that maximum temperature and material flow velocity are produced by stepped-conical pin profile tool with respect to all other tools. It is observed from the iso-viscosity surface analysis that a vaseshaped geometry developed around the contact region of the tool and workpiece. The weld zone shape produced by stepped-conical pin profile tool is cylinder dominant vase shape, and weld zone shape of all other tools is basin dominant vase shape. Numerical model was also validated with experimental results of temperature distribution and weld zone shape thickness which showed good agreement.

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