Denoising of A Mixed Noise Color Image Through Special Filter

Sandeep Kumar Agarwal,Prateek Kumar 보안공학연구지원센터 2016 International Journal of Signal Processing, Image Vol.9 No.1

Image denoising is the manipulation of the image data to produce a visually high quality image. At present there are a variety of methods to remove noise from digital images. There are different types of filters like mean filter, median filter, bilateral filter, wiener filter etc. to remove a single type of noise such as salt and pepper noise, speckle noise, Gaussian noise etc. But if the image is corrupted by mixed noise then these filters do not remove the noise exactly. Here a white flower image has been taken for denoising purpose. The white flower image is corrupted by mixed noise at zero mean and different variances to produce different noisy images at zero mean and respective variances. Noisy image is denoised by discrete wavelet transform (DWT) denoising technique using ‘Haar’ wavelet and different filters like median filter, wiener filter and bilateral filter one-by-one to produce noise free image as much as possible. Different parameters like MSE (mean square error), PSNR (peak signal to noise ratio), RMSE (root mean square error), SNR (signal to noise ratio) and SSIM (structural similarity index) estimate the performance of all filters. Special filter is designed with the help of these performance estimations so that a better filter for mixed noise image denoising purpose can be implemented. All mixed noisy images are denoised by the special filters and their performance parameters are estimated. The special filter is a combination of various filters and denoising techniques to remove of mixed noise from a digital image. The comparisons between noisy and denoised images of the special filter and other filters are presented in the form of graphs and tables.

Evaluation of efficacy of Valsalva maneuver for attenuating propofol injection pain: a prospective, randomized, single blind, placebo controlled study

Sanjay Kumar,Sandeep Khuba,Anil Agarwal,Sujeet Gautam,Madhulika Yadav,Aanchal Dixit 대한마취통증의학회 2018 Korean Journal of Anesthesiology Vol.71 No.6

Background: Pain on injection is a limitation with propofol use. The effect of the Valsalva maneuver on pain during propofol injection has not been studied. This maneuver reduces pain through the sinoaortic baroreceptor reflex arc and by distraction. We aimed to assess the efficacy of the Valsalva maneuver in reducing pain during propofol injection. Methods: Eighty American Society of Anesthesiologists class I adult patients undergoing general anesthesia were enrolled and divided into two groups of 40 each. Group I (Valsalva) patients blew into a sphygmomanometer tube raising the mercury column up to 30 mmHg for 20 seconds, while Group II (Control) patients did not. Anesthesia was induced with 1% propofol immediately afterwards. Pain was assessed on a 10-point visual analog scale (VAS), where 0 represented no pain, and 10, the worst imaginable pain, and a 4-point withdrawal response score, where 0 represented no pain, and 3, the worst imaginable pain. Scores were presented as median (interquartile range). Results: We analyzed the data of 70 patients. The incidence of pain was significantly lower in the Valsalva than in the control group (53% vs. 78%, P = 0.029). The withdrawal response score was significantly lower in the Valsalva group (1.00 [0.00–1.00] vs. 2.00 [2.00–3.00], P < 0.001). The VAS score was significantly lower in the Valsalva group (1.00 [0.00–4.00] vs. 7.00 [6.25–8.00], P < 0.001). Conclusions: A prior Valsalva maneuver is effective in attenuating injection pain due to propofol; it is advantageous in being a non-pharmacological, safe, easy, and time-effective technique.

The effect of Valsalva maneuver in attenuating skin puncture pain during spinal anesthesia: a randomized controlled trial

Sanjay Kumar,Sujeet Kumar Singh Gautam,Devendra Gupta,Anil Agarwal,Sanjay Dhirraj,Sandeep Khuba 대한마취통증의학회 2016 Korean Journal of Anesthesiology Vol.69 No.1

Background: Valsalva maneuver reduces pain by activating sinoaortic baroreceptor reflex arc. We planned this study to evaluate the role of valsalva in attenuating spinal needle-puncture pain. Methods: Ninety American Society of Anesthesiologists (ASA) grade I and II enrolled patients undergoing elective surgery were randomized into 3 groups of 30 each. Group I (Control): didn’t blow; group II (Distraction): patients blew into rubber tube; Group III (Valsalva): blew into sphygmomanometer tube and raise mercury column up to 30 mmHg for at least 20 seconds. During above procedures, spinal puncture was performed with 25-gauge spinal needle. Results: Eighty-two patient data were analyzed. Incidence of spinal puncture pain was reduced to 10% (3 of 27) in Valsalva group as compared to 100% (28 of 28 in control group and 27 of 27 in Distraction group) observed in other two groups (P < 0.05). Severity of lumbar puncture pain as assessed by visual analog scale (0−10; where 0 is no pain and 10 is the worst imaginable pain) presented as Median (Interquartile range) were significantly reduced in the Valsalva group (0.0 [0.0] as compared to other 2 groups 2.0 [0.0] in the Distraction group and 3.0 [0.8] in Control group) (P < 0.05). Regarding time taken by CSF to fill spinal needle hub, there was no difference among the three groups (P > 0.05). None patient of all groups had post dural puncture headache (P > 0.05). Conclusions: Valsalva can be performed routinely in ASA I and II patients undergoing spinal anesthesia as it is safe, painless and non-pharmacological method of pain attenuation.

Electroencephalography-based imagined speech recognition using deep long short-term memory network

Prabhakar Agarwal,Sandeep Kumar 한국전자통신연구원 2022 ETRI Journal Vol.44 No.4

This article proposes a subject-independent application of brain–computer interfacing (BCI). A 32-channel Electroencephalography (EEG) device is used to measure imagined speech (SI) of four words (sos, stop, medicine, washroom) and one phrase (come-here) across 13 subjects. A deep long short-term memory (LSTM) network has been adopted to recognize the above signals in seven EEG frequency bands individually in nine major regions of the brain. The results show a maximum accuracy of 73.56% and a network prediction time (NPT) of 0.14 s which are superior to other state-of-the-art techniques in the literature. Our analysis reveals that the alpha band can recognize SI better than other EEG frequencies. To reinforce our findings, the above work has been compared by models based on the gated recurrent unit (GRU), convolutional neural network (CNN), and six conventional classifiers. The results show that the LSTM model has 46.86% more average accuracy in the alpha band and 74.54% less average NPT than CNN. The maximum accuracy of GRU was 8.34% less than the LSTM network. Deep networks performed better than traditional classifiers.

Analysis of Wavelet Denoising of a Colour ImageWith Different Types of Noises

Prateek Kumar,Sandeep Kumar Agarwal 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.6

There are various types of noises that affect quality of an image such as Salt-and-pepper noise, Poison noise, Gaussian noise, Speckle noise etc. Wavelet is a powerful tool for denoising a variety of signals. Here a White Flower image has been taken for denoising purpose with the help of HAAR Transform. The noisy image is first decomposed into five levels to obtain different frequency bands. Then hard thresholding method is used to remove the noisy coefficients by fixing the optimum thresholding value. In this paper, analysis of a colored image is carried out with four different noises at zero mean that are applied on the image to produce noisy images. Residual image is obtained from the original and noisy image & its statistical parameters such as mean, median, mode, standard deviation, mean absolute deviation, median absolute deviation are calculated. In order to enhance the quality of the noisy images, performance parameters of denoised images must be estimated. The comparison between noisy and denoised image is taken in terms of MSE (mean square error), PSNR (peak signal to noise ratio), RMSE (root mean square error), SNR (signal to noise ratio) and SSIM (structural similarity index).

Prevention of epidural catheter migration: a comparative evaluation of two tunneling techniques

Gautam Sujeet,Agarwal Anil,Das Pravin Kumar,Khuba Sandeep,Kumar Sanjay 대한마취통증의학회 2021 Korean Journal of Anesthesiology Vol.74 No.1

BackgroundEpidural analgesia failure episodes can be reduced by catheter fixation techniques with a lower incidence of catheter migration. In this clinical study, we compared the roles of two epidural catheter tunneling techniques for the prevention of epidural catheter migration.MethodsPatients undergoing major abdominal surgery were randomized into three groups of 50 patients each based on the method used to secure the epidural catheter. In the control group (CG), the epidural catheter was secured without tunneling. Tunneling groups 1 and 2 (TG1 and TG2) were defined as tunneling with and without a catheter loop, respectively. The primary outcome measure was the migration of the epidural catheter, while the secondary outcome measures were the adequacy of analgesia and signs of inflammation. All patients were followed up by the acute pain service team twice daily in the postoperative period until the epidural catheter was removed. The results were analyzed by the one-way analysis of variance (ANOVA), chi-square test, and Fisher’s exact test. P values <0.050 were considered significant.ResultsThe three groups were similar with respect to patient characteristics. Catheter migration was significantly reduced in TG2 (two patients) compared to those in the other two groups, i.e., TG1 (eight patients) (P = 0.045) and CG (17 patients) (P = 0.001). No differences were found amongst the three groups in analgesia adequacy and catheter site inflammation (P > 0.050).ConclusionsCatheter migration was significantly reduced by tunneling without a catheter loop in TG2 as compared to the other two groups. Therefore, we suggest routine use of tunneling without a catheter loop technique in anesthesia practice and look forward to future studies with larger sample sizes.

A Multicentre, Multinational, Open-Label, 52-Week Extension Study of Gemigliptin (LC15-0444) Monotherapy in Patients with Type 2 Diabetes Mellitus

양세정,민경완,Sandeep Kumar Gupta,박중열,Vyankatesh K. Shivane,Pankaj Kumar Agarwal,김두만,김용승,백세현 대한당뇨병학회 2021 Diabetes and Metabolism Journal Vol.45 No.4

The purpose of this extension study was to assess the long-term efficacy and safety of gemigliptin 50 mg in patients with type 2 diabetes mellitus (T2DM). Patients with T2DM who had completed the initial 24-week study comparing gemigliptin monotherapy with placebo were eligible to enrol. In the open-label, 28-week extension study, all enrolled patients received gemigliptin, regardless of the treatment received during the initial 24-week study period. The mean reduction±standard deviation (SD) in glycosylated hemoglobin (HbA1c) observed after 24 weeks of treatment (-0.6%±1.1%) was further decreased for the gemi-gemi group and the mean change in HbA1c at week 52 from baseline was -0.9%±1.2% (P<0.0001). For the pbo-gemi group, HbA1c decreased after they were switched to gemigliptin, and the mean change in HbA1c at week 52 from baseline was -0.7%±1.2% (P<0.0001). Furthermore, the overall incidence of adverse events demonstrated that gemigliptin was safe and well tolerated up to 52 weeks.

Evaluation of the Efficacy of Methylprednisolone, Etoricoxib and a Combination of the Two Substances to Attenuate Postoperative Pain and PONV in Patients Undergoing Laparoscopic Cholecystectomy: A Prospective, Randomized, Placebo-controlled Trial

Gautam, Sujeet,Agarwal, Amita,Das, Pravin Kumar,Agarwal, Anil,Kumar, Sanjay,Khuba, Sandeep The Korean Pain Society 2014 The Korean Journal of Pain Vol.27 No.3

Background: Establishment of laparoscopic cholecystectomy as an outpatient procedure has accentuated the clinical importance of reducing early postoperative pain, as well as postoperative nausea and vomiting (PONV). We therefore planned to evaluate the role of a multimodal approach in attenuating these problems. Methods: One hundred and twenty adult patients of ASA physical status I and II and undergoing elective laparoscopic cholecystectomy were included in this prospective, randomized, placebo-controlled study. Patients were divided into four groups of 30 each to receive methylprednisolone 125 mg intravenously or etoricoxib 120 mg orally or a combination of methylprednisolone 125 mg intravenously and etoricoxib 120 mg orally or a placebo 1 hr prior to surgery. Patients were observed for postoperative pain, fentanyl consumption, PONV, fatigue and sedation, and respiratory depression. Results were analyzed by the ANOVA, a Chi square test, the Mann Whitney U test and by Fisher's exact test. P values of less than 0.05 were considered to be significant. Results: Postoperative pain and fentanyl consumption were significantly reduced by methylprednisolone, etoricoxib and their combination when compared with placebo (P<0.05). The methylprednisolone + etoricoxib combination caused a significant reduction in postoperative pain and fentanyl consumption as compared to methylprednisolone or etoricoxib alone (P<0.05); however, there was no significant difference between the methylprednisolone and etoricoxib groups (P>0.05). The methylprednisolone and methylprednisolone + etoricoxib combination significantly reduced the incidence and severity of PONV and fatigue as well as the total number of patients requiring an antiemetic treatment compared to the placebo and etoricoxib (P<0.05). Conclusions: A preoperative single-dose administration of a combination of methylprednisolone and etoricoxib reduces postoperative pain along with fentanyl consumption, PONV, antiemetic requirements and fatigue more effectively than methylprednisolone or etoricoxib alone or a placebo.

Unexplained episode of sensory-motor deficit following lumbar epidural analgesia

Mukherjee, Dibyadip,Gautam, Sujeet,Agarwal, Anil,Khuba, Sandeep,Kumar, Sanjay The Korean Pain Society 2019 The Korean Journal of Pain Vol.32 No.1

Evaluation of the Efficacy of Methylprednisolone, Etoricoxib and a Combination of the Two Substances to Attenuate Postoperative Pain and PONV in Patients Undergoing Laparoscopic Cholecystectomy: A Prospective, Randomized, Placebo-controlled Trial

Sujeet Gautam,Amita Agarwal,Pravin Kumar Das,Anil Agarwal,Sanjay Kumar,Sandeep Khuba 대한통증학회 2014 The Korean Journal of Pain Vol.27 No.3

Background: Establishment of laparoscopic cholecystectomy as an outpatient procedure has accentuated the clinical importance of reducing early postoperative pain, as well as postoperative nausea and vomiting (PONV). We therefore planned to evaluate the role of a multimodal approach in attenuating these problems. Methods: One hundred and twenty adult patients of ASA physical status I and II and undergoing elective laparoscopic cholecystectomy were included in this prospective, randomized, placebo-controlled study. Patients were divided into four groups of 30 each to receive methylprednisolone 125 mg intravenously or etoricoxib 120 mg orally or a combination of methylprednisolone 125 mg intravenously and etoricoxib 120 mg orally or a placebo 1 hr prior to surgery. Patients were observed for postoperative pain, fentanyl consumption, PONV, fatigue and sedation, and respiratory depression. Results were analyzed by the ANOVA, a Chi square test, the Mann Whitney U test and by Fisher’s exact test. P values of less than 0.05 were considered to be significant. Results: Postoperative pain and fentanyl consumption were significantly reduced by methylprednisolone, etoricoxib and their combination when compared with placebo (P<0.05). The methylprednisolone + etoricoxib combination caused a significant reduction in postoperative pain and fentanyl consumption as compared to methylprednisolone or etoricoxib alone (P<0.05); however, there was no significant difference between the methylprednisolone and etoricoxib groups (P>0.05). The methylprednisolone and methylprednisolone + etoricoxib combination significantly reduced the incidence and severity of PONV and fatigue as well as the total number of patients requiring an antiemetic treatment compared to the placebo and etoricoxib (P<0.05). Conclusions: A preoperative single-dose administration of a combination of methylprednisolone and etoricoxib reduces postoperative pain along with fentanyl consumption, PONV, antiemetic requirements and fatigue more effectively than methylprednisolone or etoricoxib alone or a placebo.