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Performance of and Pressure Elevation Formed by Small-diameter Microtubes Used in Constant-flow Sets
Sae Woon Sohn,노명규,Jong-Hyun Lee,Kyoung-Nam Kim,Chang-sik Kim,Byung Heon Ahn 대한안과학회 2016 Korean Journal of Ophthalmology Vol.30 No.3
Purpose: We explored the performance of and pressure elevation caused by small-diameter microtubes usedto reduce overfiltration. Methods: Using a syringe pump-driven constant-flow setting (2 μL/min), pressures were measured for polytetrafluoroethylene(PTFE) microtubes 5 mm in length with inner diameters of 51, 64, and 76 μm and for polyetherblock amide (PEBAX) microtubes with an inner diameter of 76 μm. Experiments (using microtubes only) wereinitially performed in air, water, and enucleated pig eyes and were repeated under the same conditions usingintraluminal 9/0 nylon stents. Results: The pressures measured in air in 51-, 64-, and 76-μm-diameter PTFE microtubes differed significantly(22.1, 16.9, and 12.2 mmHg, respectively; p < 0.001), and that of the 76-μm-diameter PEBAX microtube was15.8 mmHg (p < 0.001 compared to the 12.2 mmHg of the 76-μm-diameter PTFE microtube). The pressuresmeasured in water also differed significantly among the three microtubes at 3.9, 3.0, and 1.4 mmHg, respectively,while that in the PEBAX microtube was 2.6 mmHg (all p < 0.001). Using the intraluminal stent, the pressurein water of the three different PTFE microtubes increased to 22.6, 18.0, and 4.1 mmHg, respectively, andthat in the PEBAX microtube increased to 10.5 mmHg (all p < 0.001). Similar trends were evident when measurementswere performed in pig eyes. Conclusions: Although microtubes of smaller diameter experienced higher pressure in air, reduction of the innerdiameter to 51 μm did not adequately increase the pressure attained in water or pig eyes. Insertion of an intraluminalstent effectively elevated the latter pressures. PEBAX microtubes created higher pressures than didPTFE microtubes.
손세운,기창원,Sae Woon Sohn,Chang Won Kee 대한안과학회 2007 대한안과학회지 Vol.48 No.4
Purpose: To evaluate the influence of myopia on the progression of normal tension glaucoma. Methods: A retrospective study of 72 patients with normal tension glaucoma who were treated from 1984. Subjects were divided into 4 groups which are myopic group (D<-1), moderate myopic group (D<-3), severe myopic group (D<-6) and non-myopic group (D>-1). The change of MD (Mean deviation) and CPSD (corrected pattern standard deviation) of non-myopic group were compared to other myopic groups. In addition, we corrected each analysis in commensurate with age, basal IOP, post treated IOP, existence of hypertension and diabetes mellitus in order to preclude the possibility which these factors would influence to the progression. Results: There was no statistically significant difference between non-myopic group and each myopic groups in MD and CPSD changes against refraction. Moreover, with the correction of other factors, there was no statistically significant difference (Mixed method, P>0.1). Conclusions: Myopia did not affect the progression of normal tension glaucoma once treated.
김미랑,손세운,기창원,Mi Rang Kim,M,D,Sae Woon Sohn,M,D,Changwon Kee,M,D 대한안과학회 2006 대한안과학회지 Vol.47 No.1
Purpose: We attempted to detect the herpes virus using a polymerase chain reaction (PCR) technique from the aqueous humor of patients who were suspected of having herpetic uveitis. Methods: We obtained aqueous humor from four patients who suffered from elevated intraocular pressure and uveitis but did not respond to steroid and intraocular pressure depressants. We employed the PCR technique for to detect herpes-virus specific DNA. Patients were treated with oral and topical acyclovir. Results: Uveitis of varying severity and progressive iris atrophy was observed in all patients. Varicella zoster virus (VZV) specific DNA was detected in two of four patients. Two patients showed a favorable course but the other two patients showed an unfavorable course due to advanced peripheral anterior synechia and corneal decompensation. Conclusions: Diagnosis of herpetic uveitis was difficult because it was not usually accompanied by dendritic corneal lesions. Herpetic uveitis should be considered whenever anterior uveitis and elevated intraocular pressure accompanies the characteristic iris atrophy. PCR was very useful in detecting the virus DNA in the aqueous humor to enable rapid diagnosis and adequate treatment.