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손세운,기창원,Sae Woon Sohn,Chang Won Kee 대한안과학회 2007 대한안과학회지 Vol.48 No.4
Purpose: To evaluate the influence of myopia on the progression of normal tension glaucoma. Methods: A retrospective study of 72 patients with normal tension glaucoma who were treated from 1984. Subjects were divided into 4 groups which are myopic group (D<-1), moderate myopic group (D<-3), severe myopic group (D<-6) and non-myopic group (D>-1). The change of MD (Mean deviation) and CPSD (corrected pattern standard deviation) of non-myopic group were compared to other myopic groups. In addition, we corrected each analysis in commensurate with age, basal IOP, post treated IOP, existence of hypertension and diabetes mellitus in order to preclude the possibility which these factors would influence to the progression. Results: There was no statistically significant difference between non-myopic group and each myopic groups in MD and CPSD changes against refraction. Moreover, with the correction of other factors, there was no statistically significant difference (Mixed method, P>0.1). Conclusions: Myopia did not affect the progression of normal tension glaucoma once treated.
김미랑,손세운,기창원,Mi Rang Kim,M,D,Sae Woon Sohn,M,D,Changwon Kee,M,D 대한안과학회 2006 대한안과학회지 Vol.47 No.1
Purpose: We attempted to detect the herpes virus using a polymerase chain reaction (PCR) technique from the aqueous humor of patients who were suspected of having herpetic uveitis. Methods: We obtained aqueous humor from four patients who suffered from elevated intraocular pressure and uveitis but did not respond to steroid and intraocular pressure depressants. We employed the PCR technique for to detect herpes-virus specific DNA. Patients were treated with oral and topical acyclovir. Results: Uveitis of varying severity and progressive iris atrophy was observed in all patients. Varicella zoster virus (VZV) specific DNA was detected in two of four patients. Two patients showed a favorable course but the other two patients showed an unfavorable course due to advanced peripheral anterior synechia and corneal decompensation. Conclusions: Diagnosis of herpetic uveitis was difficult because it was not usually accompanied by dendritic corneal lesions. Herpetic uveitis should be considered whenever anterior uveitis and elevated intraocular pressure accompanies the characteristic iris atrophy. PCR was very useful in detecting the virus DNA in the aqueous humor to enable rapid diagnosis and adequate treatment.