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Study of TiCN Aditions to an 2xxx Series Aluminium Alloy
Ruiz-Navas E.M.,Delgado Tienda M.L.,Benito Gonzalez S.,Gordo E. 한국분말야금학회 2006 한국분말야금학회 학술대회논문집 Vol.2006 No.1
The increasing demand of PM parts for automobile and aerospace applications has caused a strong development of the aluminium based metal matrix composites (MMCs).Aluminium alloys are one of most widely used materials as matrix in MMCs, both in research and development as well as in industrial applications. In the present work, the influence of the ceramic reinforcement addition to a 2xxx series aluminium alloy is studied. Several percentages of TiCN have been added to the Al-Cu alloy using PM techniques, in order to analyze its influence on the liquid phase sintering process and on the final properties of the material.
Commissioning Status of the Linac for the Facility for Rare Isotope Beams
Lidia S.,Ao H.,Barnes B.,Bennett R.,Bernal-Ruiz E.,Bollen G.,Brandon J.,Bull B.,Bultman N.,Casagrande F.,Chabot D.,Cogan S.,Compton C.,Davidson K.,Daykin E.,Georgiobani D.,Gibson P.,Grender I.,Kim S.- 한국물리학회 2020 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.77 No.5
The Facility for Rare Isotope Beams will be completed in late 2021. We report here on the current efforts to commission the first stages of the 200-MeV/u superconducting, continuous wave heavy-ion linac. The statuses of the cryogenic plant and its distribution system, the accelerator cryomodule commissioning and operations, the ion source and front end transport development, the radio-frequency quadrupole commissioning, and thenbeam dynamics development to support high-power operation are reviewed. Plans for commissioning the remainder of the linac systems are presented.
Energy-based damage index for steel structures
E. Bojórquez,A. Terán-Gilmore,S.E. Ruiz,A. Reyes-Salazar 국제구조공학회 2010 Steel and Composite Structures, An International J Vol.10 No.4
Ample research effort has been oriented into developing damage indices with the aim of estimating in a reasonable manner the consequences, in terms of structural damage and deterioration, of severe plastic cycling. Although several studies have been devoted to calibrate damage indices for steel and reinforced concrete members; currently, there is a challenge to study and calibrate the use of such indices for the practical evaluation of complex structures. The aim of this paper is to introduce an energy-based damage index for multi-degree-offreedom steel buildings that accounts explicitly for the effects of cumulative plastic deformation demands. The model has been developed by complementing the results obtained from experimental testing of steel members with those derived from analytical studies regarding the distribution of plastic demands on several steel frames designed according to the Mexico City Building Code. It is concluded that the approach discussed herein is a promising tool for practical structural evaluation of framed structures subjected to large energy demands.
Murillo, M.,Herrera, E.,Carrete, F.O.,Ruiz, O.,Serrato, J.S. Asian Australasian Association of Animal Productio 2012 Animal Bioscience Vol.25 No.10
The objective of the study was to quantify annual and seasonal differences in the chemical composition, in vitro gas production, in situ degradability and ruminal fermentation of grazing steers… diets. Diet samples were collected with four esophageal cannulated steers ($350{\pm}3$ kg BW); and four ruminally cannulated heifers ($342{\pm}1.5$ kg BW) were used to study the dry matter degradation and fermentation in rumen. Data were analyzed with repeated measurements split plot design. The crude protein, in vitro dry matter digestibility and metabolizable energy were higher during the first year of trial and in the summer (p<0.01). The values of calcium, phosphorus, magnesium, zinc and copper were higher in summer (p<0.05). The gas produced by the soluble and insoluble fractions, as well as the constant rate of gas production were greater in summer and fall (p<0.01). The ammonia nitrogen ($NH_3N$) and total volatile fatty acids concentrations in rumen, the soluble and degradable fractions, the constant rate of degradation and the effective degradability of DM and NDF were affected by year (p<0.05) and season (p<0.01). Our study provides new and useful knowledge for the formulation of protein, energetic and mineral supplements that grazing cattle need to improve their productive and reproductive performance.
A thioredoxin fold protein Sh3bgr regulates Enah and is necessary for proper sarcomere formation
Jang, D.G.,Sim, H.J.,Song, E.K.,Medina-Ruiz, S.,Seo, J.K.,Park, T.J. Academic Press 2015 Developmental Biology Vol.405 No.1
The sh3bgr (SH3 domain binding glutamate-rich) gene encodes a small protein containing a thioredoxin-like fold, SH3 binding domain, and glutamate-rich domain. Originally, it was suggested that increased expression of Sh3bgr may cause the cardiac phenotypes in Down's syndrome. However, it was recently reported that the overexpression of Sh3bgr did not cause any disease phenotypes in mice. In this study, we have discovered that Sh3bgr is critical for sarcomere formation in striated muscle tissues and also for heart development. Sh3bgr is strongly expressed in the developing somites and heart in Xenopus. Morpholino mediated-knockdown of sh3bgr caused severe malformation of heart tissue and disrupted segmentation of the somites. Further analysis revealed that Sh3bgr specifically localized to the Z-line in mature sarcomeres and that knockdown of Sh3bgr completely disrupted sarcomere formation in the somites. Moreover, overexpression of Sh3bgr resulted in abnormally discontinues thick firmaments in the somitic sarcomeres. We suggest that Sh3bgr does its function at least partly by regulating localization of Enah for the sarcomere formation. In addition, we provide the data supporting Sh3bgr is also necessary for proper heart development in part by affecting the Enah protein level.
Proposed minimal standards for the use of genome data for the taxonomy of prokaryotes
Chun, Jongsik,Oren, Aharon,Ventosa, Antonio,Christensen, Henrik,Arahal, David Ruiz,da Costa, Milton S.,Rooney, Alejandro P.,Yi, Hana,Xu, Xue-Wei,De Meyer, Sofie,Trujillo, Martha E. Microbiology Society 2018 International journal of systematic and evolutiona Vol.68 No.1
Synaptic Vesicle Protein 2 (SV2) Isoforms
Bandala, Cindy,Miliar-Garcia, A.,Mejia-Barradas, C.M.,Anaya-Ruiz, M.,Luna-Arias, J.P.,Bazan-Mendez, C.I.,Gomez-Lopez, M.,Juarez-Mendez, S.,Lara-Padilla, E. Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
New molecular markers of cancer had emerged with novel applications in cancer prevention and therapeutics, including for breast cancer of unknown causes, which has a high impact on the health of women worldwide. The purpose of this research was to detemine protein and mRNA expression of synaptic vesicle 2 (SV2) isoforms A, B and C in breast cancer cell lines. Cultured cell lines MDA-MB-231, SKBR3, T47D were lysed and their protein and mRNA expression analyzed by real-time PCR and western blot technique, respectively. SV2A, B proteins were identified in non-tumor (MCF-10A) and tumor cell lines (MDA-MB-231 and T47D) while SV2C only was found in the T47D cell line. Furthermore, the genomic expression was consistent with protein expression for a such cell line, but in MDA-MB-231 there was no SV2B genomic expression, and the SV2C mRNA and protein were not found in the non tumoral cell line. These findings suggest a possible cellular transdifferentiation to neural character in breast cancer, of possible relevance to cancer development, and point to possible use of SV2 as molecular marker and a vehicle for cancer treatment with botulinum toxin.