http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Evaluation of Xpert MTB/RIF assay performance in the diagnosis of abdominal tuberculosis
( Suraj Kumar ),( Sawan Bopanna ),( Saurabh Kedia ),( Pratap Mouli ),( Rajan Dhingra ),( Rajesh Padhan ),( Mikashmi Kohli ),( Jigyasa Chaubey ),( Rohini Sharma ),( Prasenjit Das ),( S Dattagupta ),( G 대한장연구학회 2017 Intestinal Research Vol.15 No.2
Background/Aims: The use of genetic probes for the diagnosis of pulmonary tuberculosis (TB) has been well described. However, the role of these assays in the diagnosis of intestinal tuberculosis is unclear. We therefore assessed the diagnostic utility of the Xpert Mycobacterium tuberculosis /rifampicin (MTB/RIF) assay, and estimated the prevalence of multidrug-resistant (MDR) TB in the Indian population . Methods: Of 99 patients recruited, 37 had intestinal TB; two control groups comprised 43 with Crohn`s disease (CD) and 19 with irritable bowel syndrome. Colonoscopy was performed before starting any therapy; mucosal biopsies were subjected to histopathology, acid-fast bacilli staining, Lowenstein-Jensen culture, and nucleic acid amplification testing using the Xpert MTB/RIF assay. Patients were followed up for 6 months to confirm the diagnosis and response to therapy. A composite reference standard was used for diagnosis of TB and assessment of the diagnostic utility of the Xpert MTB/RIF assay. Results: Of 37 intestinal TB patients, the Xpert MTB/RIF assay was positive in three of 37 (8.1%), but none had MDR-TB. The sensitivity, specificity, positive predictive value, and negative predictive value of the Xpert MTB/RIF assay was 8.1%, 100%, 100%, and, 64.2%, respectively. Conclusions: The Xpert MTB/RIF assay has low sensitivity but high specificity for intestinal TB, and may be helpful in endemic tuberculosis areas, when clinicians are faced with difficulty differentiating TB and CD. Based on the Xpert MTB/RIF assay, the prevalence of intestinal MDR-TB is low in the Indian population. (Intest Res 2017;15:187- 194)
Kim, Hee Kyung,Serai, Suraj,Lindquist, Diana,Merrow, Arnold C,Horn, Paul S,Kim, Dong Hoon,Wong, Brenda L American Roentgen Ray Society 2015 American Journal of Roentgenology Vol.205 No.2
<P>The purpose of this study is to validate the use of MR spectroscopy (MRS) in measuring muscular fat and to compare it with T2 maps in differentiating boys with Duchenne muscular dystrophy (DMD) from healthy boys.</P>
( Sawan Bopanna ),( Maitreyee Roy ),( Prasenjit Das ),( S Dattagupta ),( V Sreenivas ),( V Pratap Mouli ),( Saurabh Kedia ),( Rajan Dhingra ),( Rajesh Pradhan ),( N Suraj Kumar ),( Dawesh P Yadav ),( 대한장연구학회 2016 Intestinal Research Vol.14 No.3
Background/Aims: Recent data suggest that the incidence of ulcerative colitis (UC) related colorectal cancer (CRC) in India is similar to that of West. The optimum method for surveillance is still a debate. Surveillance with random biopsies has been the standard of care, but is a tedious process. We therefore undertook this study to assess the yield of random biopsy in dysplasia surveillance. Methods: Between March 2014 and July 2015, patients of UC attending the Inflammatory Bowel Disease clinic at the All India Institute of Medical Sciences with high risk factors for CRC like duration of disease >15 years and pancolitis, family history of CRC, primary sclerosing cholangitis underwent surveillance colonoscopy for dysplasia. Four quadrant random biopsies at 10 cm intervals were taken (33 biopsies). Two pathologists examined specimens for dysplasia, and the yield of dysplasia was calculated. Results: Twenty-eight patients were included. Twenty-six of these had pancolitis with a duration of disease greater than 15 years, and two patients had associated primary sclerosing cholangis. No patient had a family history of CRC. The mean age at onset of disease was 28.89±8.73 years and the duration of disease was 19.00±8.78 years. Eighteen patients (64.28%) were males. A total of 924 biopsies were taken. None of the biopsies revealed any evidence of dysplasia, and 7/924 (0.7%) were indefinite for dysplasia. Conclusions: Random biopsy for surveillance in longstanding extensive colitis has a low yield for dysplasia and does not suffice for screening. Newer techniques such as chromoendoscopy-guided biopsies need greater adoption.
Endoscopic Ultrasound-Guided Fine-Needle Aspiration of the Adrenal Glands: Analysis of 21 Patients
Rajesh Puri,Ragesh Babu Thandassery,Narendra S. Choudhary,Hardik Kotecha,Smruti Ranjan Misra,Suraj Bhagat,Manish Paliwal,Kaushal Madan,Neeraj Saraf,Haimanti Sarin,Mridula Guleria,Randhir Sud 대한소화기내시경학회 2015 Clinical Endoscopy Vol.48 No.2
Background/Aims: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) cytology of adrenal masses helps in etiological diagnosis. The aim of this study was to evaluate the diagnostic yield of EUS-FNA of adrenal masses in cases where other imaging methods failed and/or were not feasible. Methods: Twenty-one consecutive patients with adrenal masses, in whom adrenal FNA was performed because conventional imaging modalities failed and/or were not feasible, were prospectively evaluated over a period of 3 years. Results: Of the 21 patients (mean age, 56±12.2 years; male:female ratio, 2:1), 12 had pyrexia of unknown origin and the other nine underwent evaluation for metastasis. The median lesion size was 2.4×1.6 cm. Ten patients were diagnosed with tuberculosis (shown by the presence of caseating granulomas [n=10] and acid-fast bacilli [n=4]). Two patients had EUS-FNA results suggestive of histoplasmosis. The other patients had metastatic lung carcinoma (n=6), hepatocellular carcinoma (n=1), and adrenal lipoma (n=1) and adrenal myelolipoma (n=1). EUS results were not suggestive of any particular etiology. No procedure-related adverse events occurred. Conclusions: EUS-FNA is a safe and effective method for evaluating adrenal masses, and it yields diagnosis in cases where tissue diagnosis is impossible or has failed using conventional imaging modalities.
Johnston, Jennifer H,Kim, Hee Kyung,Merrow, Arnold C,Laor, Tal,Serai, Suraj,Horn, Paul S,Kim, Dong Hoon,Wong, Brenda L American Roentgen Ray Society, etc.] 2015 American Journal of Roentgenology Vol.205 No.2
<P>OBJECTIVE. The purpose of this study was to validate derived T2 maps as an objective measure of muscular fat for discrimination between boys with Duchenne muscular dystrophy (DMD) and healthy boys. SUBJECTS AND METHODS. Forty-two boys with DMD (mean age, 9.9 years) and 31 healthy boys (mean age, 11.4 years) were included in the study. Age, body mass index, and clinical function scale grade were evaluated. T1-weighted MR images and T2 maps with and without fat suppression were obtained. Fatty infiltration was graded 0-4 on T1-weighted images, and derived T2 fat values (difference between mean T2 values from T2 maps with and without fat suppression) of the gluteus maximus and vastus lateralis muscles were calculated. Group comparisons were performed. The upper limit of the 95% reference interval of T2 fat values from the control group was applied. RESULTS. There was no significant difference in age or body mass index between groups. All healthy boys and 19 boys (45.2%) with DMD had a normal clinical function scale grade. Grade 1 fatty infiltration was seen in 90.3% (gluteus maximus) and 71.0% (vastus lateralis) of healthy boys versus 33.3% (gluteus maximus) and 52.4% (vastus lateralis) of boys with DMD. T2 fat values of boys with DMD were significantly longer than in the control group (p < 0.001). Using a 95% reference interval for healthy boys for the gluteus maximus (28.3 milliseconds) allowed complete separation from boys with DMD (100% sensitivity, 100% specificity), whereas the values for the vastus lateralis (7.28 milliseconds) resulted in 83.3% sensitivity and 100% specificity. CONCLUSION. Measurement of muscular fat with T2 maps is accurate for differentiating boys with DMD from healthy boys.</P>
Anisotropy and deformation heterogeneity in additive manufactured carbon-reinforced PEEK
Vipin Gupta,N. I. Thiruselvam,D. M. Kulkarni,V. V. Chaudhari,S. Suraj 대한기계학회 2023 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.37 No.6
Carbon-reinforced polyether ether ketone (C-PEEK) is one of the highperformance thermoplastic polymers used in engineering applications. To manufacture C-PEEK parts, a material extrusion process called fused deposition modeling (FDM) is more preferred than other 3D printing technologies such as material jetting, sheet lamination, VAT photopolymerization, binder jetting, directed energy deposition (DED) and powder bed fusion (PBF) due to its low cost and high efficiency. In FDM, the angle between printing and loading directions, called raster angle, is a known cause of material anisotropy. However, less attention has been paid to bring out the effect of raster angle on local state of strain. We fill this gap using digital image correlation (DIC) and scanning electron microscopy (SEM). Standard specimens made using three different raster angles, namely, 0°, 45°, and 90°, were tested upto failure by fracture. 0° raster angle offers the highest strength, whereas 90° raster angle yields the least strength. All specimens fail by brittle fracture. Strain localization that evolves near interfaces between two beads or layers play the most vital role in the failure mechanism.