Effect of Bradyrhizobium japonicum on Chlorophyll Content, Nodulation, and Plant Growth in Soybean

Roshan Sharma Poudyal,B. N. Prasad 韓國作物學會 2005 Korean journal of crop science Vol.50 No.4

Study on effectiveness of Bradyrhizobium japonicum on soybean [Glycine max (L.) Merr.], local cultivar 'Sathiya' were carried out in the garden soil of Trib-huvan University. Different parameters like nodulation, chlorophyll content in fresh leaves and growth of plant in inoculated and uninoculated plant was studied. Pot experiment was conducted in the green house to evaluate the effectiveness of B. japonicum on soybean. It was observed that B. japonicum inoculation increased the number of nodules, shoot length of plant and total chlorophyll content in fresh leaves of soybean plant. However, root length was decreased in all inoculated plants.

Effects of strip-tilled cover cropping on the population density of thrips and predatory insects in a cucurbit agroecosystem

Roshan Manandhar,Koon-Hui Wang,Cerruti R.R. Hooks,Mark G. Wright 한국응용곤충학회 2017 Journal of Asia-Pacific Entomology Vol.20 No.4

Strip-till cover cropping provides a structurally complex habitat (both diverse above ground vegetation and modified soil surface environment) in subsequent crops, which can contribute to suppressing herbivores in the cash crop, through either enhancing conservation biological control or altering herbivore behavior to the complex habitat. Two field trials (spring and autumn) were conducted to examine effects of strip-tilled cover crops (sunn hemp and marigold) on population densities of thrips (primarily, Frankliniella occidentalis and Thrips palmi) and generalist predators (Orius spp. and ground beetles, Aephnidius spp.) in cucurbit plantings. The results showed that strip-tilled cover crop treatments reduced thrips densities on cucurbit crops compared to the conventional monoculture. The strip-tilled treatments suppressed thrips densities more consistently in the autumn than in the spring trial. The reduced densities of thrips in strip-tilled cover crop plots were not attributable to the enhanced activity of predatory insects, but were most likely due to the disruption of host locating ability of thrips. Our study showed that the strip-till cover cropping could be an effective pest management technique for sustainable cucurbit production.

FACTORS AFFECTING ENERGY EFFICIENCY INVESTMENTS

Roshan Chhetri,Duane Robinson,Young-Ho LEE 한국신재생에너지학회 2017 AFORE Vol.2017 No.11

Preparation and evaluation of 17-allyamino- 17-demethoxygeldanamycin (17-AAG)-loaded poly(lactic acid-co-glycolic acid) nanoparticles

Roshan Pradhan,Bijay Kumar Poudel,최주연,최임순,신범수,최한곤,용철순,김종오 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.5

In the present study, we developed the novel17-allyamino-17-demethoxygeldanamycin (17-AAG)-loadedpoly(lactic acid-co-glycolic acid) (PLGA) nanoparticles(NPs) using the combination of sodium lauryl sulfateand poloxamer 407 as the anionic and non-ionic surfactantfor stabilization. The PLGA NPs were prepared by emulsification/solvent evaporation method. Both the drug/polymer ratio and phase ratio were 1:10 (w/w). The optimizedformulation of 17-AAG-loaded PLGA NPs had aparticle size and polydispersity index of 151.6 ± 2.0 and0.152 ± 0.010 nm, respectively, which was further supportedby TEM image. The encapsulation efficiency anddrug loading capacity were 69.9 and 7.0 %, respectively. In vitro release study showed sustained release. Whenin vitro release data were fitted to Korsmeyer–Peppasmodel, the n value was 0.468, which suggested that thedrug was released by anomalous or non-Fickian diffusion. In addition, 17-AAG-loaded PLGA NPs in 72 h, displayedapproximately 60 % cell viability reduction at 10 lg/ml17-AAG concentration, in MCF-7 cell lines, indicatingsustained release from NPs. Therefore, our resultsdemonstrated that incorporation of 17-AAG into PLGANPs could provide a novel effective nanocarrier for thetreatment of cancer.

Microwave-assisted one pot-synthesis of amino acid ionic liquids in water: simple catalysts for styrene carbonate synthesis under atmospheric pressure of CO2

Roshan, K.,Jose, T.,Kim, D.,Cherian, K.,Park, D. Royal Society of Chemistry 2014 Catalysis Science & Technology Vol.4 No.4

A novel variety of ionic liquids based on naturally occurring amino acids is expeditiously synthesized in water using microwave energy. The amino acid ionic liquids (AAILs) exhibit eminent catalytic activities towards the synthesis of styrene carbonate from styrene oxide and carbon dioxide at atmospheric pressure. The synergistic interaction of the hydrogen-bonding groups with the nucleophile in the AAIL is believed to be the key factor behind the catalytic cycloaddition. Among the various kinds of AAILs tested, the basic AAILs were found to be the most efficient owing to the presence of extra amino groups that could activate the carbon dioxide molecule by formation of a carbamate salt. The AAILs showed appreciable reusability over four cycles without compromising the selectivity towards styrene carbonate synthesis and hence represents an easily synthesizable series of eco-friendly catalysts for CO2 fixation.

Fabrication of a uniformly sized fenofibrate microemulsion by membrane emulsification

( Roshan Pradhan ),( Dong Won Lee ),( Han Gon Choi ),( Chul Soon Yong ),( Jong Oh Kim ) 영남대학교 약품개발연구소 2013 영남대학교 약품개발연구소 연구업적집 Vol.23 No.0

Fenofibrate-loaded microemulsions composed of Labrafil M 1944 CS, Capryol PGMC and fenofibrate as the dispersed phase and Labrasol in demineralised water as the continuous phase were prepared by utilising a Shirasu-porous-glass (SPG) membrane emulsification technique. The process parameters were optimised by adjusting the feed pressure (15-45 kPa), agitator speed (250-800 rpm) and temperature of the continuous phase (25-45°C). As a result, narrowly distributed microemulsions were obtained via SPG membrane emulsification at an agitator speed of 250 rpm, a feed pressure of 30 kPa and a continuous phase temperature of 25°C. Furthermore, TEM images clearly showed that the microemulsionprepared by SPG membrane emulsification had a uniform, spherical morphology with a narrow size distribution. Our results indicated that the SPGmembrane emulsification technique is highly efficient for the preparation of narrowly distributed microemulsions with relatively smaller particle sizes compared with the common stirring method.

COMINIMAXNESS OF LOCAL COHOMOLOGY MODULES WITH RESPECT TO IDEALS OF DIMENSION ONE

Roshan-Shekalgourabi, Hajar The Honam Mathematical Society 2018 호남수학학술지 Vol.40 No.2

Let R be a commutative Noetherian ring, a be an ideal of R and M be an R-module. It is shown that if $Ext^i_R(R/a,M)$ is minimax for all $i{\leq}{\dim}\;M$, then the R-module $Ext^i_R(N,M)$ is minimax for all $i{\geq}0$ and for any finitely generated R-module N with $Supp_R(N){\subseteq}V(a)$ and dim $N{\leq}1$. As a consequence of this result we obtain that for any a-torsion R-module M that $Ext^i_R(R/a,M)$ is minimax for all $i{\leq}dim$ M, all Bass numbers and all Betti numbers of M are finite. This generalizes [8, Corollary 2.7]. Also, some equivalent conditions for the cominimaxness of local cohomology modules with respect to ideals of dimension at most one are given.

Development of a rebamipide solid dispersion system with improved dissolution and oral bioavailability

Roshan Pradhan,Tuan Hiep Tran,최주연,최임순,최한곤,용철순,김종오 대한약학회 2015 Archives of Pharmacal Research Vol.38 No.4

The purpose of this study was to improve thegastric solubility and bioavailability of rebamipide (RBM)by preparing the RBM solid dispersion tablet (RBM-SDT)from solid dispersion powder prepared by spray-dryingtechnique. For preparation of rebamipide solid dispersions(RBM-SDs), solubility study was performed in varioushydrophilic carriers and alkalizers, among which sodiumalginate and sodium carbonate were selected as thehydrophilic polymer and alkalizer, respectively. Differentcombinations of drug–polymer–alkalizer were dissolved inaqueous solution and spray-dried in order to obtain soliddispersions. Noticeable improvement in aqueous solubility(approximately 200 times) and in vitro dissolution rate wasobserved by RBM-SDs, compared to RBM powder. Theoptimized formulation of RBM-SD powder consisted ofRBM powder/sodium alginate/sodium carbonate at theweight ratio of 1/2/2. The transformation of crystallineRBM to amorphous RBM-SD powder was clearly demonstratedby powder X-ray diffraction, differential scanningcalorimetry (DSC) and scanning electron microscopy. The optimized RBM-SD was formulated in tablet dosageform, containing approximately 2 % sodium lauryl sulphateand poloxamer F68 as wetting agents. The RBMSDTexhibited enhanced dissolution in hydrochloric acidbuffer (pH 1.2) and distilled water. Moreover, pharmacokineticstudy in rats showed higher AUC and Cmax forRBM-SDT than those for RBM powder and commercialproduct. Thus, the developed RBM-SDT formulation canbe more efficacious for improving oral bioavailability ofRBM.

The unprecedented catalytic activity of alkanolamine CO₂ scrubbers in the cycloaddition of CO₂ and oxiranes: a DFT endorsed study

Roshan, Kuruppathparambil Roshith,Kim, Bo Mi,Kathalikkattil, Amal Cherian,Tharun, Jose,Won, Yong Son,Park, Dae Won The Royal Society of Chemistry 2014 Chemical communications Vol.50 No.89

<P>A novel application of alkanolamines, widely employed as CO<SUB>2</SUB> scrubbers in catalyzing the insertion of CO<SUB>2</SUB> into epoxides generating cyclic carbonates in excellent yield and selectivity <I>via</I> the synergistic activity of hydroxyl and amine groups, is unravelled along with computational studies.</P> <P>Graphic Abstract</P><P>A novel use of alkanolamines as catalysts for CO<SUB>2</SUB> conversion to cyclic carbonates under metal- and halide-free conditions. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c4cc04195j'> </P>

Long-Term Results of Endoscopic Lumbar Discectomy by “Destandau’s Technique”

Roshan Bhaisare,Bhavna Kamble,Kisan Patond 대한척추외과학회 2016 Asian Spine Journal Vol.10 No.2

Study Design: Prospective study. Purpose: The aim of the study was to present long-term results from a 10-year follow-up after endoscopic lumbar discectomy (ELD) by “Destandau’s technique”. Overview of Literature: Endoscopic disc surgery by Destandau’s technique using ENDOSPINE Karl Storz system is a relatively new technique. It was introduced in 1993. It has been gaining popularity among the spine surgeons, as it is attractive for small skin incision and allows a gentle and excellent tissue dissection with excellent visualization. Many authors have published results of their own studies; however, in all these studies the long-term follow up of the patients has not been emphasized. Methods: A total of 21 patients selected on basis of strict inclusion criteria’s underwent ELD from November 2004 to March 2005. Surgery outcome was assessed by using “Prolo’s Anatomic-Functional-Economic Rating System” (1986). Patients were followed up to 10 years. In addtion, we compared the results of our study with other studies. Results: Outcomes were excellent in 17 patients (80.95%), good in 3 (14.28%) and fair in 1 (4.78%), with no patients having a poor result. In our study, 19 patients (90.47%) were able to resume their previous works/jobs, and only 2 (9.52%) needed to change their jobs for lighter work. No patient retired from his or her previous daily routine following the operation. Conclusions: The initial and long-term results are very good for endoscopic lumbar discectomy by Destandau’s technique. In properly selected patients it is a safe and minimally invasive technique, and we recommend ELD in properly selected patients.