Impact of long-term high-intensity interval and moderate-intensity continuous training on subclinical inflammation in overweight/obese adults

José Gerosa-Neto,Barbara M.M. Antunes,Eduardo Z. Campos,Jhennyfer Rodrigues,Gustavo D. Ferrari,José C. Rosa Neto,Carlos R. Bueno Junior,Fábio S. Lira 한국운동재활학회 2016 JER Vol.12 No.6

Numerical analysis of the mechanical behavior of welded I beam-to-RHS column connections

Rosa, Rosicley J.R.,Neto, Juliano G.R. Techno-Press 2019 Coupled systems mechanics Vol.8 No.2

Considering the increasing use of tubular profiles in civil construction, this paper highlights the study on the behavior of welded connections between square hollow section column and I-beam, with emphasis on the assessment of the joint stiffness. Firstly, a theoretical analysis of the welded joints has been done focusing on prescriptions of the technical literature for the types of geometries mentioned. Then, a numerical analysis of the proposed joints were performed by the finite element method (FEM) with the software ANSYS 16.0. In this study, two models were evaluated for different parameters, such as the thickness of the cross section of the column and the sizes of cross section of the beams. The first model describes a connection in which one beam is connected to the column in a unique bending plane, while the second model describes a connection of two beams to the column in two bending planes. From the numerical results, the bending moment-rotation ($M-{\varphi}$) curve was plotted in order to determine the resistant bending moment and classify each connection according to its rotational capacity. Furthermore, an equation was established with the aim of estimating the rotational stiffness of welded I beam-to-RHS column connections, which can be used during the structure design. The results show that most of the connections are semi-rigid, highlighting the importance of considering the stiffness of the connections in the structure design.

Interaction between quinclorac and imidazolinones in the control of resistant Cyperus iria to ALS inhibitors

Avila Neto Roberto Costa,de Souza Pablo Mazzuco,Rubert Jaine,Seibt Tiago André,Thomasi Rosana Marzari,Melo Adriano Arrué,Alves Marcelo Plada,da Rosa Ulguim André 한국작물학회 2023 Journal of crop science and biotechnology Vol.26 No.2

Herbicides belonging to the chemical group imidazolinones and the quinclorac herbicide are important to control weeds in fooded rice. The objective of this research was to evaluate the interaction of imidazolinones with quinclorac to control Cyperus iria resistant to acetolactate synthase inhibitors (ALS). It was conducted two experiments in a greenhouse in a completely randomized design with four replications. Colby’s methodology was used for experiment 1, through the application of quinclorac isolated and in mixture with herbicides imazethapyr, imazapyr e imazapic. The experiment 2, using dose–response curves, tested the herbicides quinclorac isolated and in diferent mixtures with the herbicide imazethapyr. For experiment 1, the expected and observed averages were compared. For experiment 2, the results were analyzed using the sigmoidal logistic model. Additive is the main interaction of mixtures of quinclorac with diferent herbicides from the chemical group of imidazolinones to control resistant C. iria. Mixing with imazethapyr at diferent proportions can cause an additive efect with quinclorac at higher doses.

Potential implications of blood flow restriction exercise on patients with chronic kidney disease: a brief review

Nicholas Rolnick,Ivo Vieira de Sousa Neto,Eduardo Fernandes da Fonseca,Rodrigo Vanerson Passos Neves,Thiago dos Santos Rosa,Dahan da Cunha Nascimento 한국운동재활학회 2022 JER Vol.18 No.2

Combining blood flow restriction (BFR) with exercise is considered a relevant, helpful method in load-compromised individuals and a viable replacement for traditional heavy-load strength training. BFR exercise may be particularly useful for those unable to withstand high mechanical stresses on joints resulting in skeletal muscle dysfunction, such as patients with chronic kidney disease (CKD). Current literature suggests that BFR training displays similar positive health benefits to exercise training alone for CKD patients, including maintenance of muscle strength, glomerular filtration rate maintenance, uremic parameters, inflammatory profile, redox status, glucose homeostasis, blood pressure adjustments, and low adverse reports. In this review of nine studies in CKD patients, we clarify the potential safety and health effects of exercise training with BFR compared to exercise training alone and recommend insights for future research and practical use. Furthermore, we introduce relevant gaps in this emerging field, providing substantial guidance, critical discussion, and valuable preliminary conclusions in this demographic of patients. However, based on the limited studies in this area, more research is necessary to determine the optimal BFR exercise programming.

Remodeling of Neuronal Circuits After Reach Training in Chronic Capsular Stroke

Cho, Jongwook,Kwon, Dae-Hyuk,Kim, Ra Gyung,Song, Hanlim,Rosa-Neto, Pedro,Lee, Min-Cheol,Kim, Hyoung-Ihl SAGE Publications 2016 Neurorehabilitation and neural repair Vol.30 No.10

<P>Background. Subcortical capsular stroke has a poor prognosis, and it is not yet fully understood how and under what circumstances reach training contributes to motor recovery. Objective. This study was performed to investigate changes in neuronal circuits and motor recovery in a chronic capsular stroke model in the presence or absence of reach training. Method. We generated photothrombotic capsular lesions in 42 Sprague-Dawley rats and evaluated motor recovery with or without daily training in a single-pellet reaching task (SPRT). We used 2-deoxy-2-[18F]-fluoro-D-glucose-microPET (positron emission tomography) to assess remodeling of neuronal circuits. Results. SPRT training was selectively beneficial only for the group with incomplete capsular destruction (P < .05), suggesting the relevance of plasticity in the remaining capsular fibers for motor recovery. Groups that did not receive SPRT training showed no motor recovery at all. The microPET analysis demonstrated that motor recovery was correlated with a reduction in cortical diaschisis in ipsilesional motor and sensory cortices and in the contralesional sensory cortex (Pearson's correlation, P < .05). We also observed training-dependent subcortical activation in the contralesional red nucleus, the internal capsule, and the ventral hippocampus (P < .0025; false discovery rate q < 0.05). The groups without reach training did not show the same degree of reduction in diaschisis or activation of the red nucleus. Conclusions. Our results suggest that motor recovery and remodeling of neuronal circuits after capsular stroke depend on the magnitude of the capsular lesion and on the presence or absence of reach training. Task-specific training is strongly indicated only when there is incomplete destruction of the capsular fibers.</P>

Evaluation of Women with Myofascial Abdominal Syndrome Based on Traditional Chinese Medicine

Mitidieri, Andreia,Gurian, Maria Beatriz,Silva, Ana Paula,Tawasha, Kalil,Poli-Neto, Omero,Nogueira, Antonio,Reis, Francisco,Rosa-e-Silva, Julio KOREAN PHARMACOPUNCTURE INSTITUTE 2015 Journal of pharmacopuncture Vol.18 No.4

Objectives: This study used semiology based on traditional Chinese medicine (TCM) to investigate vital energy (Qi) behavior in women with abdominal myofascial pain syndrome (AMPS). Methods: Fifty women diagnosed with chronic pelvic pain (CPP) secondary to AMPS were evaluated by using a questionnaire based on the theories of "yin-yang," "zang-fu", and "five elements". We assessed the following aspects of the illness: symptomatology; specific location of myofascial trigger points (MTrPs); onset, cause, duration and frequency of symptoms; and patient and family history. The patients tongues, lips, skin colors, and tones of speech were examined. Patients were questioned on various aspects related to breathing, sweating, sleep quality, emotions, and preferences related to color, food, flavors, and weather or seasons. Thirst, gastrointestinal dysfunction, excreta (feces and urine), menstrual cycle, the five senses, and characteristic pain symptoms related to headache, musculoskeletal pain, abdomen, and chest were also investigated. Results: Patients were between 22 and 56 years old, and most were married (78%), possessed a elementary school (66%), and had one or two children (76%). The mean body mass index and body fat were 26.86 kg/cm2 (range: 17.7 - 39.0) and 32.4% (range: 10.7 - 45.7), respectively. A large majority of women (96%) exhibited alterations in the kidney meridian, and 98% had an altered gallbladder meridian. We observed major changes in the kidney and the gallbladder Qi meridians in 76% and 62% of patients, respectively. Five of the twelve meridians analyzed exhibited Qi patterns similar to pelvic innervation Qi and meridians, indicating that the paths of some of these meridians were directly related to innervation of the pelvic floor and abdominal region. Conclusion: The women in this study showed changes in the behavior of the energy meridians, and the paths of some of the meridians were directly related to innervation of the pelvic floor and abdominal region.

Sensory-parietal cortical stimulation improves motor recovery in severe capsular infarct

Kim, Ra Gyung,Cho, Jongwook,Ree, Jinkyue,Kim, Hyung-Sun,Rosa-Neto, Pedro,Kim, Jin-Myung,Lee, Min-Cheol,Kim, Hyoung-Ihl SAGE Publications 2016 Journal of cerebral blood flow and metabolism Vol.36 No.12

<P> The prevalence of subcortical white matter strokes in elderly patients is on the rise, but these patients show mixed responses to conventional rehabilitative interventions. To examine whether cortical electrical stimulation can promote motor recovery after white matter stroke, we delivered stimulation to a small or wide region of sensory-parietal cortex for two weeks in a rodent model of circumscribed subcortical capsular infarct. The sham-operated group (SOG) showed persistent and severe motor impairments together with decreased activation in bilateral sensorimotor cortices and striatum. In contrast, sensory-parietal cortex stimulation significantly improved motor recovery: final recovery levels were 72.9% of prelesion levels in the wide stimulation group (WSG) and 37% of prelesion levels in the small stimulation group (SSG). The microPET imaging showed reversal of cortical diaschisis in both groups: in both hemispheres for the WSG, and in the hemisphere ipsilateral to stimulation in the SSG. In addition, we observed activation of the corpus callosum and subcortical corticostriatal structures after stimulation. The results from the c-Fos mapping study were grossly consistent with the microPET imaging. Sensory-parietal cortex stimulation may therefore be a useful strategy for overcoming the limits of rehabilitative training in patients with severe forms of subcortical capsular infarct. </P>

Evaluation of Women with Myofascial Abdominal Syndrome Based on Traditional Chinese Medicine

Andréia Mitidieri,Maria Beatriz Gurian,Ana Paula Silva,Kalil Tawasha,Omero Poli-Neto,Antônio Nogueira,Francisco Reis,Júlio Rosa-e-Silva 대한약침학회 2015 Journal of pharmacopuncture Vol.18 No.4

Objectives: This study used semiology based on traditionalChinese medicine (TCM) to investigate vital energy(Qi) behavior in women with abdominal myofascialpain syndrome (AMPS). Methods: Fifty women diagnosed with chronic pelvicpain (CPP) secondary to AMPS were evaluated by usinga questionnaire based on the theories of “yin-yang,”“zang-fu”, and “five elements”. We assessed the followingaspects of the illness: symptomatology; specific locationof myofascial trigger points (MTrPs); onset, cause, durationand frequency of symptoms; and patient and familyhistory. The patients tongues, lips, skin colors, and tonesof speech were examined. Patients were questioned onvarious aspects related to breathing, sweating, sleepquality, emotions, and preferences related to color, food,flavors, and weather or seasons. Thirst, gastrointestinaldysfunction, excreta (feces and urine), menstrual cycle,the five senses, and characteristic pain symptoms relatedto headache, musculoskeletal pain, abdomen, andchest were also investigated. Results: Patients were between 22 and 56 years old,and most were married (78%), possessed a elementaryschool (66%), and had one or two children (76%). Themean body mass index and body fat were 26.86 kg/cm2(range: 17.7 — 39.0) and 32.4% (range: 10.7 — 45.7), respectively. A large majority of women (96%) exhibitedalterations in the kidney meridian, and 98% hadan altered gallbladder meridian. We observed majorchanges in the kidney and the gallbladder Qi meridiansin 76% and 62% of patients, respectively. Five of thetwelve meridians analyzed exhibited Qi patterns similarto pelvic innervation Qi and meridians, indicatingthat the paths of some of these meridians were directlyrelated to innervation of the pelvic floor and abdominalregion. Conclusion: The women in this study showed changesin the behavior of the energy meridians, and the pathsof some of the meridians were directly related to innervationof the pelvic floor and abdominal region.

Genotoxicity of Turnera subulata and Spondias mombin × Spondias tuberosa Extracts from Brazilian Caatinga Biome

Tiago Felipe Senes-Lopes,Jorge Alberto Lo´pez,Viviane Souza do Amaral,Jose´ Branda˜o-Neto,Adriana Augusto de Rezende,Jefferson Roma´ryo Duarte da Luz,Zaira da Rosa Guterres,Maria das Grac¸as Almeida 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.4

Medicinal plants have been used in primary healthcare since the earliest days of humankind. Turnera subulata and Spondias mombin × Spondias tuberosa are widely used in the Brazilian Northeast to treat several diseases. The aim of this study was to evaluate the genotoxic effects of the leaf extracts of these species by the somatic mutation and recombination test in the somatic cells of Drosophila melanogaster wings. The experiments were performed using standard and high-bioactivation cross and three concentrations of the test substance [aqueous extract (AET and AES) at 5.0, 10.0, and 20.0 mg/mL and ethanolic extract (EET and EES) and ethyl acetate fraction (EAFT and EAFS) at 0.625, 1.25, and 2.5 mg/mL]. Results indicated that the extracts and fractions induced spontaneous frequencies of mutant spots in both D. melanogaster crosses. Nevertheless, the highest concentrations of the tested plant chemical agents were responsible for the statistically significant genotypic effect. T. subulata and S. mombin × S. tuberosa displayed genotoxic effect under the experimental conditions. The results from this study are crucial as they indicated the deleterious and side effects, considering the indiscriminate use of the extracts of these plants for disease treatment.