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        Effect of Macleaya cordata and Magnolia officinalis plant extracts on oxidative stress control in lambs fed a high-concentrate diet

        Lima, Tiago Ronimar Ferreira,Gallo, Sarita Bonagurio,Rosa, Alessandra Fernandes,Silva, Saulo da Luz e,Brochado, Thais,Bezerra, Helena Viel Alves,Putrino, Soraia Marques,Martins, Marcela Buosi,Leme, Pa Asian Australasian Association of Animal Productio 2020 Animal Bioscience Vol.33 No.6

        Objective: The objective of this experiment was to compare conventional antioxidants and plant extracts for oxidative stress control in lambs fed a high-concentrate diet. Methods: Forty-eight male Dorper×Santa Ines lambs with an initial weight of 20±1.49 kg and 60 days of age, were used to evaluate the effects of feeding a combination of Macleaya cordata and Magnolia officinalis plant extracts (0 vs 320 mg/kg dry matter [DM]) in combination with selenium+vitamin E (0 vs 100 IU/kg DM of vitamin E and 0.1 mg/kg DM of selenium) in a completely randomized block design in a 2×2 factorial arrangement. The animals were housed in individual pens and received a high-concentrate diet consisting of 80% whole corn and 20% protein pellet for 60 days. The animals were weighed at the beginning of the experiment and every 14 days for performance monitoring. Three blood samplings were performed during the experimental period for the evaluation of oxidative and protein parameters. Results: The treatments with vitamin E and selenium as additives had a positive influence on final weight, daily weight gain, carcass weight, and selenium content in longissimus muscle (p = 0.01). Plant extracts tended to improve final weight (p = 0.064) and daily weight gain (p = 0.059), showing similar effect as selenium and vitamin E. There was no effect of treatment on blood proteins, indicating that the animals were healthy throughout the experiment. Conclusion: The use of plant extracts had a similar effect as the addition of selenium and vitamin E, with dietary inclusion of additives resulting in better performance of lambs but both supplements did not have strong influence on oxidative stress.

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        Geochemistry of mudrock units from the Meso-Cenozoic Algarve Basin, Portugal

        Maria J. Trindade,Maria I. Dias,Fernando Rocha,Maria I. Prudêncio,Rosa Marques 한국지질과학협의회 2018 Geosciences Journal Vol.22 No.5

        Geochemistry of mudrock units deposited in the sedimentary basin of Algarve (South Portugal) during Mesozoic and Cenozoic depositional cycles were studied, aiming a better knowledge of the evolution of the Basin. Two types of mudrock units were found: (i) silicic and Ca-poor (Cretaceous and Cenozoic), and (ii) calcareous (Middle–Upper Jurassic Ca-rich mudrock units and Upper Triassic to Lower Jurassic Mg-rich redbeds). LILE appear to be controlled by a K-bearing phyllosilicate, which is consistent with the abundant illite in the redbeds. Positive trends of: (i) Sc, Cr, Th, LREE with Al2O3 suggests their incorporation in clay minerals, and (ii) HREE with TiO2, Zr and Hf point to their presence in heavy minerals. The source area of the Algarve mudrock units was dominated by felsic rocks; features typical of a mafic source occur in some Upper Triassic to Lower Jurassic samples. Carboniferous metasediments of the basement were probably the first order source for the Algarve sedimentary basin. A more severe weathering in the Cenozoic and Cretaceous mudrock units occurred, whereas diagenetic enrichment in potassium is observed in the Upper Triassic to Lower Jurassic continental redbeds.

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        Cuphea calophylla var. mesostemon (Koehne) S.A. Graham: A Whole-Ethnopharmacological Investigation

        Lislaine Maria Klider,Camila Dias Machado,Valter Paes de Almeida,Cleide Adriane Signor Tirloni,Aline Aparecida Macedo Marques,Rhanany Alan Calloi Palozi,Bethânia Rosa Lorençone,Paulo Vitor Moreira Rom 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.4

        Several species of Cuphea are used medicinally and are reported to have cardioprotective, diuretic, and antihypertensive properties. In Brazil, Cuphea species are collectively called “sete-sangrias” due to their similar appearances and are also used interchangeably for the same therapeutic purposes. So the aim of the study was to characterize morphoanatomy of leaves and stems, evaluate the safety, and investigate the diuretic, hypotensive, vasodilatory, and antioxidant properties of ethanol-soluble fraction of Cuphea calophylla var. mesostemon (Koehne) S.A. Graham. Initially, the morphoanatomical characterization of the leaves and stems of C. calophylla var. mesostemon was performed. For the pharmacological evaluation, the ethanol-soluble fraction from Cuphea calophylla (ESCC) was obtained and chemically characterized by high-performance liquid chromatography coupled with a diode array detector and tandem mass spectrometry techniques. Then, acute toxicity, diuretic, hypotensive, antioxidant, and vasodilatory effects were evaluated in Wistar rats. The main chemical compounds identified from ESCC were gallic acid derivatives, ellagitannins, and flavonoids. ESCC showed no acute toxic effect. ESCC showed no acute toxic effect and the estimated median lethal dose (LD50) was above 2000 mg/kg. ESCC treatment (30, 100, and 300 mg/kg) did not present any significant acute diuretic or hypotensive effects. However, an important reduction in the elimination of electrolytes was observed after the acute administration, and a significant increase in renal sodium elimination was observed after 7 days of treatment. In the cardiac tissue, the groups treated with ESCC presented significant increase in superoxide dismutase activity.

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