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- 저자 : Rongwu Wang (검색결과 3 건)
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Jiatai Gu,Zhenzhen Quan,Liming Wang,Hongnan Zhang,Ni Wang,Xiaohong Qin,Rongwu Wang,Jianyong Yu 한국섬유공학회 2022 Fibers and polymers Vol.23 No.6
Membranes with the functions of waterproofness and breathability are of great interest due to their huge scientificand commercial value in many practical applications. However, designing such membranes with a desirable performance bysimple and efficient fabrication process remains a tremendous challenge. Herein, novel binary structured composite fibrousmembranes were developed for waterproof and breathable applications via simple one-step multi-jet electrospinningtechnology. This composite membranes were made up of polyvinylidene fluoride (PVDF) and polyacrylonitrile (PAN). PVDF was incorporated into the PAN fiber matrix as a modifier to improve the hydrophobic behavior of fibers. Meanwhile,PVDF microspheres/fibers were employed as building blocks to orderly embed in PAN/PVDF fiber framework, impartingthe composite membranes with fluffy micro-nano hierarchical structures. Consequently, with the integrated features of robusthydrophobicity as well as elaborate fiber-microsphere binary structure, the resultant composite membranes exhibitedsynergistically modest waterproof and breathable performances with the hydrostatic pressure of 18.04 kPa, water vaportransmittance (WVT) rate of 4.65 kg m-2 d-1, and air permeability of 64.19 mm s-1. This simple preparation process andunique composite structure may provide a new insight to design and fabricate waterproof and breathable membranes forvariously potential applications, including the protective clothing, separation membrane, and filter.
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Pan Zhang,Gaihuan Ren,Lulu Tian,Bo Li,Zhanzhao Li,Hongqin Yu,Rongwu Wang,Jianxin He 한국섬유공학회 2022 Fibers and polymers Vol.23 No.8
The waterproof and moisture permeable fabric with thermal regulation not only has the protective function forhuman body, but also meets the comfort of human clothing, which is a challenging and innovative research. Herein, we reportan environmentally friendly, simple, and high-efficiency strategy to fabricate waterproof and breathable nanofibermembranes with outstanding thermal regulation ability by introducing stearic acid (SA) into the hydrophobic siliceouspolyurethane (SIPU) solution by a facile one-step electrospinning. Owing to the addition of SA, the waterproofness of SIPU/SA nanofiber membranes is greatly improved, meanwhile, the addition of SA acted as a phase change material to imparttemperature regulation performance in appropriate temperature range to the SIPU/SA nanofiber membranes. By adjusting theaddition amount of the SA, eco-friendly and multifunctional SIPU/SA nanofiber membranes are systemically optimized withgood waterproofness (79 kPa), moisture breathability (8.0 kg m-2 d-1), and outstanding temperature regulation performance(latent heat up to 40 J/g), satisfied tensile strength (6.2 MPa) and excellent breaking elongation of 182 %. The obtained SIPU/SA nanofiber membranes can be suitable for the design of multifunctional wearable textiles for various applications,especially in outdoor protective clothing, medical clothing, intelligent clothing and military products.
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Rong Wu,Sen Zhou,Minglong Liu,Haiqian An,Zhe Wang,Tianxi Liu 연세대학교의과대학 2022 Yonsei medical journal Vol.63 No.3
Purpose: Vascular calcification (VC) is a common complication of end-stage renal disease (ESRD). This study aimed to examinechanges in the expression of miR-21-5p in ESRD patients with VC and to explore its clinical value in predicting the occurrenceand progression of uremic VC. Materials and Methods: 120 ESRD patients were divided into patients without VC group (n=38) and patients with VC group(n=82). All patients were followed up for 2 years to evaluate VC progression. qRT-PCR was used to detect serum miR-21-5p levels. Receiver operating characteristic curves were constructed to assess diagnostic value. Kaplan-Meier and log-rank methods wereutilized to calculate associations between VC progression and risk factors. Results: Serum miR-21-5p levels were significantly higher in ESRD patients with VC than in those without VC and increased progressivelywith increasing disease severity. Serum miR-21-5p levels were able to distinguish patients with VC from those withoutVC, with an area under the curve value of 0.883, a sensitivity of 81.7%, and a specificity of 84.2%. After 2 years of follow-up, miR-21-5p expression had increased in patients with worse VC severity, compared with those with stable VC severity. Patients withhigh miR-21-5p levels were more likely to develop more severe VC, indicating an association between miR-21-5p and VC progression(log-rank p=0.002). Multivariable Cox regression analysis suggested that serum miR-21-5p is an independent predictive factorof VC progression in ESRD patients (hazard ratio=2.064, 95% confidence interval=1.225–3.478, p=0.006). Conclusion: miR-21-5p is overexpressed in the serum of ESRD patients with VC. Our results suggest that overexpression of miR-21-5p is closely associated with VC progression.
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