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류진호,정경운,위준선,문정미,전병조,문원식,김용권,소정일,허탁,민용일 대한응급의학회 2001 대한응급의학회지 Vol.12 No.4
Background: Although cardiopulmonary resuscitation(CPR) is a very effective therapy in cardiac arrest, it is hard to prove the true effectiveness of CPR. Several studies about out-of-hospital and emergency department CPR exist, but only a few reports about in-hospital CPR are available. This study was designed to investigate in-hospital cardiac arrest, to analyze the result of CPR, and to evaluate the problems associated with in-hospital CPR. Methods: A clinical analysis of 71 cases of in-hospital CPR announcement from January 2000 to August 2000 was performed. The initial rhythm on cardiac arrest, return of spontaneous circulation(ROSC), and the survivals were analyzed in the case of the 46 true cardiac arrest patients. Results: During 8 months, there were 71 cases of in-hospital CPR announcement. Among them, there were 46 cases of true cardiac arrest and 25 cases of non-cardiac arrest. Of the 46 true cardiac-arrest cases, 27(58.7%) experienced ROSC, 15(32.6) survived for over 24 hours, and 7(15.2%) survived to be discharged. The initial rhythms on cardiac arrest were 30 cases(65.2%) of asystole, 14(30.4%) of PEA(pulseless electrical activity), and 2(4.3%) of ventricular fibrillation, with ROSC being 17 cases(56.7%), 9(64.3%) and 1(50.0%) cases and discharged survivors being 4 cases(13.3%), 3(21.4%) and 0(0.0%) cases, respectively. Conclusion: Extraordinarily high proportions of asystole and PEA were seen in the initial rhythm of cardiac arrest, and those were associated with high survival rates. Although further study is needed to evaluate the course leading to this high proportion of asystole and PEA, this result suggests that if the EMS system in the hospital is activated promptly and systematically, a better outcome will be achieved in case of cardiac arrest with asystole and PEA.
김준호,류무수,이몽희 한국색채교육학회 1998 한국색채조형학회지 Vol.7 No.1
The various ways of measuring colors have been. developed as the role of colors becomes important nowadays. But the colors bear meanings and get the appeal through the longuage, too. The color adjectives in Korean have various derivational forms. This peper is to study the structure of the color adjectives in Korean, and to analyse the actual use conditions of them, and thus to find out the corresponding color values to them.
부인과암에서 P-Glycoprotein 발현에 관한 면역조직화학적 연구
손영선,노홍태,류춘수,이오성 대한부인종양 콜포스코피학회 1997 Journal of Gynecologic Oncology Vol.8 No.1
The expression of P-glycoprotein in gynecological tissues was studied by immunohi-stochemical staining methods. Aspects of study included the expression of P-glycoprotein in different tissues throughout the clinical treatment regimen, the relationship between the expression of P-glycoprotein and the degree of pathologic malignancy, and the expression of P-glycoprotein in cancerous tissue before and after chemotherapy. Studies were based on patients who were admitted to the Department of Obstetrics and Gynecology of Chungnam National University Hospital from January 1988 to December 1993. Tissue samples collected prior to chemotherapy included 34 ovarian cancers, 73 cervical cancers, and ll endometrial cancers. Pre and post-chemotherapy tissue samples included 11 ovarian cancers and 15 cervical cancers. Normal tissue samples included 12 from the ovaries, 15 from the cervix, and 10 from the endometrium. Result are as follows : 1. P-glycoprotein was mainly found in the cytoplasm of both normal tissue cells and cells of tissuess prior to chemotherapy. After chemotherapy it was found more intensely in the cell membrane than in the cytoplasm. 2. For normal tissue, P-glycoprotein was found in 25% of ovarian tissues, 33.3% of uterine cervical tissues, and 40.0% of endometrial tissues. 3. For canverous tissues prior to chemotherapy, P-glycoprotein was found in 45.5% of ovarian cancer cases, 47.9% of uterine cervical cancer cases, and 45.5% of endometrial cancer cases. There was no stastically meaningful difference in these rates in cancerous normal tissues. 4. The expression of P-glycoprotein in cancerous tissues prior to chemotherapy was not related to histologic type. 5. For ovarian cancer tissue, P-glycoprotein was expressed in 45.5% of cases prior to chemotherapy, and 54.4% of cases subsequent to chemotherapy. For uterine cervical cancer tissue, P-glycoprotein expression rates before and after chemotherapy was 46.7% and 60.0% respectively and there was a statistically meaningful difference(p$lt;0.05) 6. There was no relationship between P-glycoprotein expression in cancer tissues after chermotherapy and the presense of cisplatin in chemotherapeutic drugs. 7. For uterine cervical cancer tissues prior to chemotherapy, there was no relationship between the degree histologic differentation and the expression of P-glycoprotein 8. For cancerous tissues there was no relationship between clinical stage and the expression of P-glycoprotein In conclusion, the expression of P-glycoprotein was identified in the tissues before the drug exposure. However, there was no relationship between the expression of P-glycoprotein and histologic type, clinical stage, and effectiveness of chemotherapy. This may be related to P-glycoprotein inducing a cellular resistance to chemotherapeutic agents, although the importance of this resitance is thought to be small. Futher studies of P-glycoprotein are needed to delineate its role in cellular anticancer drug resistance.
Systemic Sclerosis Sine Scleroderma
김채기 ( Chae Gi Kim ),류헌모 ( Hun Mo Rhoo ),권중구 ( Joong Goo Kwon ),이창형 ( Chang Hyeong Lee ),송용호 ( Yong Ho Song ),최정윤 ( Jung Yoon Choe ) 대한류마티스학회 2000 대한류마티스학회지 Vol.7 No.3
Systemic sclerosis (SSc) is a generalized connective tissue disorder of unknown etiology. Clinically, there is a broad spectrum of disease ranging from widespread severe skin thickening to skin thickening limited to the distal extremities. In rare cases of systemic sclerosis, no cutaneous change only with internal organ involvement has been reported, which is called `systemic sclerosis sine scleroderma (ssSSc)`. We describe a patient with Raynaud`s phenomenon, who showed intestinal pseudoobstruction as a presenting symptom but did not show any skin change. She had also an esophageal motility disorder, but other organ involvement was not evident. Antinuclear antibody was positive. Her obstruction symptoms were improved by decompression by nasogastric tube and pharmaceutical treatment with erythromycin and octreotide.
고혈압 환자에서 24 시간 활동 혈압과 좌심실비대와의 상관관계에 대한 연구
김상욱(Sang Wook Kim),유재격(Jae Kyuk Rhoo),김현대(Hyun Dae Kim),이은우(Eun Woo Lee),이성윤(Sung Yun Lee),박승호(Seung Ho Park),류왕성(Wang Seong Ryu),유언호(Un Ho Ryoo) 대한내과학회 1993 대한내과학회지 Vol.45 No.1
N/A Background: 24-hour noninvasive ambulatory blood pressure monitoring (ABPM) has been shown to be superior to casual BP in predicting target organ involvement in patients with hypertension and assessing anti-hypertensive therapy. This study was done to examine the relation of BP decline from day to night to the echocardiographic parameters of left ventricular anatomy in unselected hypertensive patients and normotensive subjects undergoing 24-hour noninvasive ABPM. Methods: The effect of variation of blood pressure on the echocardiographic parameters of left ventricular hypertrophy were investigated in 71 consecutive subjects. (47 patients with essential hypertension and 24 healthy normotensive subjects). 24-hour noninvasive ambulatory blood pressure monitoring and cross-sectional and M-mode echocardiography were done to examine the relation between ABPM and echocardiographic LVH. Results: 24-hour ambulatory blood pressure was lower than casual blood pressure, and weak relation was noted particularly in patients with mild-to-moderate hypertension. The continuous monitoring of BP throughout day shows characteristic circadian pattern. The highest BP was recorded at 10 am and lowest value was at 2 am-4 am. Ambulatory daytime blood pressure (6 am-8pm) was higher 15% than night-time blood pressure (8 pm-6 am), The correlation coefficient of daytime systolic blood pressure was r=0.42 (p<0.01), twenty-four hours systolic BP was r=0.41 (p<0.05). The daytime and 24 hours systolic BP seems to be more closely related to LVH than night-time BP, but the correlation was not high enough in our study. Conclusion: 24-hour ambulatory blood pressure monitoring is more useful than casual BP in patients with hypertension, and LVH in echocardiography is more closely related to daytime and 24 hours systolic BP than night-time BP.