Research on Improved Hadoop Distributed File System in Cloud Rendering

Ren Qin,Gao Jue,Gao Honghao,Bian Minjie,Xu Huahu,Feng Weibing 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.11

With the rapid development of cloud computing technology, it’s the cloud rendering that cloud computing is applied to render the job in CG (Computer Graphic) industry. The cloud rendering can handle a large number of rendering requests which are enormous pressure for back-end servers in system. Facing with massive data and computing resources, the bottleneck of original HDFS (Hadoop Distributed File System) based on cloud computing has become more and more prominent, such as the failure of single Namenode, scalability issues. Therefore, the paper proposed an improved HDFS which evolved a single Namenode into multi-Namenode. In HDFS, Metadata management is very important. So this paper presented a two-level Metadata distribution algorithm. The two-level algorithm was based on the principle that different distribution strategies were used to different categories of Metadata. The experiments verified that the improved HDFS effectively improved the performance of the system.

The role of titanium nitride supports for single-atom platinum-based catalysts in fuel cell technology

Zhang, Ren-Qin,Lee, Tae-Hun,Yu, Byung-Deok,Stampfl, Catherine,Soon, Aloysius The Royal Society of Chemistry 2012 Physical chemistry chemical physics Vol.14 No.48

<P>As a first step towards a microscopic understanding of single-Pt atom-dispersed catalysts on non-conventional TiN supports, we present density-functional theory (DFT) calculations to investigate the adsorption properties of Pt atoms on the pristine TiN(100) surface, as well as the dominant influence of surface defects on the thermodynamic stability of platinized TiN. Optimized atomic geometries, energetics, and analysis of the electronic structure of the Pt/TiN system are reported for various surface coverages of Pt. We find that atomic Pt does not bind preferably to the clean TiN surface, but under typical PEM fuel cell operating conditions, <I>i.e.</I> strongly oxidizing conditions, TiN surface vacancies play a crucial role in anchoring the Pt atom for its catalytic function. Whilst considering the energetic stability of the Pt/TiN structures under varying N conditions, embedding Pt at the surface N-vacancy site is found to be the most favorable under N-lean conditions. Thus, the system of embedding Pt at the surface N-vacancy sites on TiN(100) surfaces could be promising catalysts for PEM fuel cells.</P> <P>Graphic Abstract</P><P>Surface nitrogen vacancies in single-atom platinized titanium nitride (Pt/TiN) offer an alternative way to design cost-effective and durable Pt-based nanocatalysts for low-temperature PEMFC applications. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c2cp41392b'> </P>

Electroacupuncture Promotes Neural Proliferation in Hippocampus of Perimenopausal Depression Rats via Wnt/β-Catenin Signaling Pathway

Qin Jing,Lu Ren,Xue Deng,Nan Zhang,Martin Fu,Ge Wang,Xi-Rong Jiang,Shu-Ru Lin,Cai-Rong Ming 사단법인약침학회 2020 Journal of Acupuncture & Meridian Studies Vol.13 No.3

Background and Objective: Perimenopausal depression is caused by the impaired function of the ovarium before menopause and with a series of symptoms. Electroacupuncture (EA) therapy has been demonstrated to improve clinically depression. However, the mechanism underlying its therapeutic activity remains unknown. This study aimed to investigat the effects of EA treatment on the hippocampal neural proliferation through Wnt signaling pathway. Methods: Chronic unpredictable mild stress (CUMS) combined with bilateral ovariectomy (OVX) were used to establish a rat model of perimenopausal depression. The open field test (OFT) and sucrose preference test (SPT) were used to assess depression-like behaviors in rats. ELISAs were used to measure estrogen (E2), luteinizing hormone (LH) and gonadotropin-releasing hormone (GnRH) levels in the serum. RT-PCR and Western blot assay were utilized for measuring the mRNA expressions and protein expressions of GSK-3β/β-catenin. Results: Four-week EA treatment at three points including “Shenshu” (BL23), “Baihui” (GV20) and “Sanyinjiao” (SP6) simultaneously ameliorated depression-like behaviors in rats with CUMS and OVX, whereas rescued the decreased serum level of E2 and prevented the increased serum levels of GnRH and LH. EA treatment ameliorated CUMS and OVX-induced alterations of glycogen synthase kinase-3b (GSK-3β) and β-catenin mRNA levels, β-catenin and phosphorylated β-catenin (p-β-catenin) protein levels. Conclusions: The results showed that EA treatment promoted hippocampal neural proliferation in perimenopausal depression rats via activating the Wnt/b-catenin signaling pathway, indicating that EA may represent an efficacious therapy for perimenopausal depression.

HDAC6 siRNA Inhibits Proliferation and Induces Apoptosis of HeLa Cells and its Related Molecular Mechanism

Qin, Hai-Xia,Cui, Hong-Kai,Pan, Ying,Yang, Jun,Ren, Yan-Fang,Hua, Cai-Hong,Hua, Fang-Fang,Qiao, Yu-Huan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.7

Objective: To investigate the effects of histone deacetylase 6 (HDAC6) siRNA on cell proliferation and cell apoptosis of the HeLa cervical carcinoma cell line and the molecular mechanisms involved. Methods: Division was into three groups: A, the untreated group; B, the control siRNA group; and C, the HDAC6 siRNA group. Lipofectamine 2000 was used for siRNA transfection, and Western blot analysis was used to determine the protein levels. Cell proliferation and apoptosis were characterized using a CCK-8 assay and flow cytometry, respectively. Results: HDAC6 protein expression in the HDAC6 siRNA-transfection group was significantly lower (P < 0.05) than in the untreated and control siRNA groups. The CCK-8 kit results demonstrated that the proliferation of HeLa cells was clearly inhibited in the HDAC6 siRNA transfection group (P < 0.05). In addition, flow cytometry revealed that the early apoptotic rate ($26.0%{\pm}0.87%$) was significantly elevated (P < 0.05) as compared with the untreated group ($10.6%{\pm}1.19%$) and control siRNA group ($8.61%{\pm}0.98%$). Furthermore, Western blot analysis indicated that bcl-2 protein expression in the HDAC6 siRNA-transfection group was down-regulated, whereas the expression of p21 and bax was up-regulated. Conclusion: HDAC6 plays an essential role in the occurrence and development of cervical carcinoma, and the down-regulation of HDAC6 expression may be useful molecular therapeutic method.

Mini-Array of Multiple Tumor-associated Antigens (TAAs) in the Immunodiagnosis of Esophageal Cancer

Qin, Jie-Jie,Wang, Xiao-Rui,Wang, Peng,Ren, Peng-Fei,Shi, Jian-Xiang,Zhang, Hong-Fei,Xia, Jun-Fen,Wang, Kai-Juan,Song, Chun-Hua,Dai, Li-Ping,Zhang, Jian-Ying Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6

Sera of cancer patients may contain antibodies that react with a unique group of autologous cellular antigens called tumor-associated antigens (TAAs). The present study aimed to determine whether a mini-array of multiple TAAs would enhance antibody detection and be a useful approach in esophageal cancer detection and diagnosis. Our mini-array of multiple TAAs consisted of eleven antigens, p53, pl6, Impl, CyclinB1, C-myc, RalA, p62, Survivin, Koc, CyclinD1 and CyclinE full-length recombinant proteins. Enzyme-linked immunosorbent assays (ELISA) were used to detect autoantibodies against eleven selected TAAs in 174 sera from patients with esophageal cancer, as well as 242 sera from normal individuals. In addition, positive results of ELISA were confirmed by Western blotting. In a parallel screening trial, with the successive addition of antigen to a final total of eleven TAAs, there was a stepwise increase in positive antibody reactions. The eleven TAAs were the best parallel combination, and the sensitivity and specificity in diagnosing esophageal cancer was 75.3% and 81.0%, respectively. The positive and negative predictive values were 74.0% and 82.0%, respectively, indicating that the parallel assay of eleven TAAs raised the diagnostic precision significantly. In addition, the levels of antibodies to seven antigens, comprising p53, Impl, C-myc, RalA, p62, Survivin, and CyclinD1, were significantly different in various stages of esophageal cancer, which showed that autoantibodies may be involved in the pathogenesis and progression of esophageal cancer. All in all, this study further supports our previous hypothesis that a combination of antibodies might acquire higher sensitivity for the diagnosis of certain types of cancer. A customized mini-array of multiple carefully-selected TAAs is able to enhance autoantibody detection in the immunodiagnosis of esophageal cancer and autoantibodies to TAAs might be reference indicators of clinical stage.

Association of Urinary Cesium with Breast Cancer Risk

Qin, Ya-Chao,Tang, Lu-Ying,Su, Yi,Chen, Li-Juan,Su, Feng-Xi,Lin, Ying,Zhang, Ai-Hua,Ren, Ze-Fang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: The aim of this study is to examine the association of urinary cesium with breast cancer risk. Materials and Methods: We collected survey data and urine specimens from 240 women with incident invasive breast cancer before their treatment and 246 age-matched female controls between October 2009 and July 2010. Urinary concentrations of cesium were determined by inductively coupled plasma mass spectrometry. Interviews were conducted by face-to-face to obtain information on potential breast cancer risk factors. Logistic regression analysis was used to estimate the associations. Results: Creatinine-adjusted levels [median ($25^{th}$, $75^{th}$) ug/g] of cesium in cases and controls were 17.6 (13.1, 24.0) and 19.3 (15.3, 25.7), respectively. After adjustment for potential risk factors, women in the second and highest tertile of cesium showed a decreased risk of breast cancer in a dose-dependent manner as compared with those in the lowest tertile [ORs and 95% CIs: 0.75 (0.46-1.22) and 0.50 (0.30-0.82), respectively]. This decrease was more evident in women with ER positive or localized clinical stage in an exploratory stratification analysis. Conclusions: These findings suggest that cesium may have anticancer efficacy and urinary cesium has potential as a biomarker for breast cancer risk assessment.

Mechanical Properties of Special-shaped Mo Fiber Reinforced Mineral-filled Polymer Composite

Xiuhua Ren,Chao Zhang,Jianhua Zhang,Peng Liu,Guangjiu Qin 한국섬유공학회 2021 Fibers and polymers Vol.22 No.2

With superior vibration alleviation property, mineral-filled polymer composite (MFPC) has attracted moreattention in the field of mechanical manufacturing. However, the application of MFPC is limited by its inferior mechanicalstrength. Straight-line and special-shaped Mo fibers were respectively added into MFPC to improve its mechanical propertiesin the paper. The influences of fiber shape and matrix performance on interface bonding property of fiber-matrix were studiedsystematically. And the effects of fiber shape and fiber content on compressive and flexural strength of MFPC wereseparately discussed. Finite element analysis was employed to further verify experimental results. Compared with straightlinefiber, both pulling ability and interfacial bonding strength of special-shaped Mo fiber are greatly improved when massratio r of resin and curing agent is identical. For the same fiber, interface bonding strength of r=4:1 is obviously greater thanthat of r=7:1. The maximum mechanical strength is achieved when mass fraction of fibers is 1.2 %. Mechanical properties ofMFPC reinforced by special-shaped fibers are much better than those reinforced by straight-line fibers. By contrast, thereinforcing effect of M-shaped fibers is optimal, followed by N-shaped, U-shaped the third, and V-shaped the minimum,which consists with the results of finite element simulation.

Five new sesquiterpene lactones from Inula hupehensis

Jie Ren,Jiang Jiang Qin,Xiangrong Cheng,Shi Kai Yan,Hui Zi Jin,Wei Dong Zhang 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.11

Four new pseudoguaianolides (1–4), one newguaianolide (5), together with ten known compounds(6–15) were isolated from the aerial parts of Inula hupehensis. Their structures were elucidated mainly on the basisof 1D and 2D spectroscopic methods and circular dichroismanalysis. In addition, compounds 1–10 and 13 weretested for their inhibitory effects against LPS-induced NOproduction in RAW264.7 macrophages. Compounds 2, 6, 8and 9 exhibited significant inhibitory activities with IC50values in the range of 0.6–6.6 lM.

Complete Parametric Solutions to the Fundamental Problem in High-order Fully Actuated System Approach

Guang-Ren Duan,Qin Zhao,Tianyi Zhao 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.1

The high-order fully actuated system (HOFAS) approach has recently been proposed, aiming at establishing a unified architecture for control of general nonlinear systems. Its core idea is to firstly obtain a HOFAS model for a dynamical system, and then to cancel the nonlinearity using the full-actuation property. Based on this, the control problem of both linear and many types of nonlinear systems is finally turned into a specific eigenstructure assignment problem of a particular matrix pair. Because of this, the specific eigenstructure assignment problem is considered as the fundamental problem of the HOFAS approach, and is investigated in detail in this paper. A general parametric solution is established in an iterative form with all the degrees of freedom provided, and special solutions for some commonly used cases are also given. These form a database for various design problems and provide some ready-to-use results. Finally, illustrative examples demonstrate the usage of the database.

Study on Dynamic Characteristics and Load Sharing of a Herringbone Planetary Gear with Manufacturing Errors

Fei Ren,Datong Qin,Teik Chin Lim,류성기 한국정밀공학회 2014 International Journal of Precision Engineering and Vol. No.

In this paper, a new and generalized dynamic model for a herringbone planetary gear train (HPGT) is proposed to investigate thefree and forced vibration characteristics, as well as load sharing characteristics by employing the lumped-parameter approach. Theproposed model takes into account manufacturing eccentric errors of the components and tooth profile errors of all gears. The modelcan be used for the vibration performance and dynamic load sharing analysis of the HPGT with different types of manufacturingerrors and arbitrary number of planets. The free and forced vibration, as well as the load sharing of an HPGT with three planetsare numerically computed with the model presented, and these are analyzed respectively in time domain and frequency domain. Theeffects of the manufacturing eccentric error and tooth profile error as well as component float on load sharing are discussedrespectively. Results indicate that manufacturing errors have an impact on dynamic characteristics and load sharing. The float cansignificantly reduce the load sharing coefficient of the system.