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Rahul Sinha(Rahul Sinha ),Sonali Singh(Sonali Singh ),Gautam Kamila(Gautam Kamila ),Ashish Upadhyay(Ashish Upadhyay ) 대한소아신경학회 2022 대한소아신경학회지 Vol.31 No.1
Purpose: This study investigated the diagnostic utility of short-term video electroencephalography (EEG) recordings at a tertiary care center in North India. Methods: A retrospective analysis was conducted of 30 minutes of video EEG recordings done between January 2021 and January 2022 in children between 1 and 10 years of age. Demographic and clinical data were collected from the EEG register. Age, sex, the clinical diagnosis, the number of anti-seizure medicines (ASMs), the activation procedures used, and EEG abnormalities were recorded. Results: Data from 100 children (male-to-female ratio, 1.9:1) were analysed. The mean age was 5.39±2.02 years. The indications for EEG recordings were epileptic disorders, neurodevelopmental disorders, paroxysmal non-epileptic events, and miscellaneous in 66%, 18%, 9%, and 7% of children, respectively. EEG abnormalities were seen in 50 children (50%) and about 45% of children were on two or more ASMs. EEG abnormalities in sleep were seen in 35 of 66 (53%) children, whereas abnormalities were observed on awake recordings with activation procedures (hyperventilation and photic) in 23 of 34 (68%) children; this difference was not statistically significant (P=0.16) Conclusion: EEG abnormalities were significantly more common in children taking multiple ASMs; however, there was no statistically significant difference in the EEG yield between asleep and awake records with activation procedures. A better selection of patients for routine EEG, through an assessment of their clinical history and comorbidities, is warranted to increase its diagnostic yield.
Rahul Sinha,Ankit Kumar Meena,Maneesh Uniyal,Sonali Singh,Ashish Upadhyay 대한소아신경학회 2024 대한소아신경학회지 Vol.32 No.1
Purpose: This study aimed to evaluate the knowledge, attitudes, and practices (KAP) of parents or caregivers of children suffering from migraines at a tertiary care center in North India. Methods: We conducted a cross-sectional study involving 100 parents or caregivers, using convenience sampling. A 20-item questionnaire was administered in English and also translated into the local language (Hindi). The study included children with migraines who visited the pediatric outpatient department within a 6-month period (December 2022 to May 2023). Results: Over 60% of caregivers were aware of the chronic nature of the illness, its triggering factors, the role of family history, and the importance of lifestyle modifications. However, only 46% understood the pathophysiology of the illness, and 53% were aware of the medication used for childhood migraines. More than 85% of caregivers believed that recurrent headaches necessitate a doctor’s consultation, may require regular visits for optimal treatment, and were willing to alter their child’s lifestyle to prevent headaches. However, a significant percentage of caregivers (47%) practised self-medication for their children’s headaches. Most caregivers believed that lifestyle modifications and avoiding triggers were the best treatments for migraines. There were significant associations (P<0.05) between the level of education and responses to questions related to migraine definition, prophylaxis, treatment, investigations, lifestyle modifications, and screen time. Conclusion: Most participants were well-educated on migraine, and their KAP regarding migraine prevention and treatment were generally adequate. However, the practice of self-medication without professional guidance is a significant concern.
Rahul Sinha,Dharmesh Soneji,Gautam Kamila,Sonali Singh,Ashish Upadhyay 대한소아신경학회 2023 대한소아신경학회지 Vol.31 No.3
Purpose: The present study investigated the clinical profile of children with primary headache at a tertiary care center in North India. Methods: A retrospective observational study was conducted between January 2021 and October 2022. In total, 100 children 5 to 18 years of age who attended the pediatric outpatient department or the emergency department with primary headache were included. Children with secondary causes of headache were excluded. Results: This study included 100 children (40 boys, 60 girls), and the female-to-male ratio was 1.5:1. The patients ranged in age from 5 to 18 years (mean±standard deviation, 10.1±2.8). Migraine headaches were most commonly reported (60%) followed by tension-type headache (28%) and others (12%). The throbbing type of pain was most common (43%), followed by the tightening type in 32%. The pain location was bilateral frontal in 47% of patients, followed by bitemporal in 20% and occipital in 17%. Most of the children (87%) had a headache duration of 2 to 4 hours. The common precipitating factors were skipped meals (25%), bright light (18%), lack of sleep (16%), and schoolwork (15%). A family history was present in around 62%. Around 70% of children required prophylactic medications (flunarizine and propranolol). Long screen time (2 to 4 hours/day) and a family history of headache were significantly associated with primary headache (P<0.05). Conclusion: The present study highlights that migraine is most common cause of primary headache in children, and every effort should be made for the early detection and management of headaches among children.
Tricholithobezoar: An Unusual Late Complication of Neourethral Reconstruction in Aphallia
Vishwajeet Singh,Deepak Sharanappa Nagathan,Rahul Janak Sinha,Dheeraj Kumar Gupta 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.5
An 18-year-old man born with aphallia had undergone phallic reconstruction in childhood followed by total urethral reconstruction with a buccal mucosal graft and groin-based pedicle (Singapore) flap urethroplasty at 13 years of age. The patient presented with obstructive voiding symptoms lasting 6 months followed by acute urinary retention. The results of a voiding cystourethrogram showed a filling defect in the distal urethra that had been reconstructed by use of the skin flap. On urethroscopy, a 3 cm×2cm sized tricholithobezoar was seen in the distal urethra. Pneumatic lithotripsy followed by bulbar urethrolithotomy was performed in the same operation to extract the bezoar. The remaining hairs were mechanically epilated. The patient has been doing well for 6 months of follow-up.
Leiomyosarcoma, a Nonurothelial Bladder Tumor: A Rare Entity With Therapeutic Diversity
Dheeraj Kumar Gupta,Vishwajeet Singh,Rahul Janak Sinha,Vijay Kumar,Deepak Sharanappa Nagathan,Satya Narayan Sankhwar 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.6
A 22-year-old young woman presented with dysuria and lower urinary tract symptoms that had persisted for 6 months. She was diagnosed with a tumor near the bladder neck. Transurethral resection was done under anaesthesia. The histopathological examination with immunohistochemical staining showed the tumor to be a low-grade leiomyosarcoma. Adjuvant chemoradiation was given, and the patient has been doing well for 12 months of follow-up. Nonurothelial tumors of the bladder are rare and consensus is lacking regarding their definitive treatment. Furthermore, little is known about the natural history and prognosis of this type of bladder sarcoma. We present a minimally invasive treatment for this relatively rare tumor in which bladder preservation was achieved with no evidence of local or distant recurrences during the follow-up to date.
Nandi, Dip K.,Sahoo, Sumanta,Kim, Tae Hyun,Cheon, Taehoon,Sinha, Soumyadeep,Rahul, Ramesh,Jang, Yujin,Bae, Jong-Seong,Heo, Jaeyeong,Shim, Jae-Jin,Kim, Soo-Hyun Elsevier 2018 Electrochemistry communications Vol.93 No.-
<P><B>Abstract</B></P> <P>Molybdenum nitride (MoN<SUB>x</SUB>) was directly grown on 3-dimensional Ni-foam (NF) at relatively low temperature of 250 °C by atomic layer deposition (ALD) and then tested as an electrode for charge storage. The successful formation of MoN<SUB>x</SUB>@NF composite was confirmed by several characterization techniques. The scanning and transmission electron microscopy analyses showed the extremely uniform and conformal coating of the MoN<SUB>x</SUB> on NF. The presence of NF influenced the redox-reactions in the composite and established the composite as a potential electrode for efficient charge-storage. High areal capacity (geometrical) of 130 mC/cm<SUP>2</SUP> was achieved at a current density of 2 mA/cm<SUP>2</SUP>. The excellent cyclic stability reflected the conducting nature of the composite.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Low temperature ALD-grown MoN<SUB>x</SUB> on 3D Ni-foam is tested as a charge-storage electrode. </LI> <LI> The uniform and conformal growth of MoN<SUB>x</SUB> on Ni-foam is confirmed. </LI> <LI> High areal capacity (130 mC/cm<SUP>2</SUP>) is achieved with >100% capacity retention. </LI> <LI> The robustness of the MoN<SUB>x</SUB>@Ni-foam composite is revealed by post-cycling analysis. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>